acompound

Showing entry for gamma-Fagarine

General Compound Information
BXGC Id	BXGC0001437
Compound Name	gamma-Fagarine
Structure
Formula	C13H11NO3
InchiKey	KFBCTNNQFGONHB-UHFFFAOYSA-N
SMILES	COC1=CC=CC2=C1N=C1OC=CC1=C2OC
Inchi	InChI=1S/C13H11NO3/c1-15-10-5-3-4-8-11(10)14-13-9(6-7-17-13)12(8)16-2/h3-7H,1-2H3
IUPAC	4,8-dimethoxyfuro[2,3-b]quinoline
Molecular Weight	229.23
Pubchem Id	107936
Chembl Id	CHEMBL252925

Targets of Information Source

DrugBank

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type

PDB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1

Binding DB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM

CHEMBL

CHEMBL252925

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
P38398	BXGT010037	Breast cancer type 1 susceptibility protein	reviewed	Enzyme	BRCA1	Potency	-	25118	nM
Q194T2	BXGT013743	Non-structural protein 1	unreviewed	-	NS1	Potency	'='	3981	nM
P80244	BXGT011887	ATP-dependent Clp protease proteolytic subunit	reviewed	-	clpP	Potency	-	15848	nM
P15428	BXGT008121	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	reviewed	-	HPGD	Potency	'='	28183	nM
P63092	BXGT011495	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	reviewed	-	GNAS	Potency	-	11220	nM
Q96QE3	BXGT019718	ATPase family AAA domain-containing protein 5	reviewed	-	ATAD5	Potency	-	20596	nM
B2RXH2	BXGT002006	Lysine-specific demethylase 4E	reviewed	-	KDM4E	Potency	'='	31622	nM
P22303	BXGT008751	Acetylcholinesterase	reviewed	Enzyme	ACHE	IC50	-	-	-
P22303	BXGT008751	Acetylcholinesterase	reviewed	Enzyme	ACHE	Inhibition	'='	24	%
P00352	BXGT005510	Retinal dehydrogenase 1	reviewed	Enzyme	ALDH1A1	Potency	'='	35481	nM
O89049	BXGT005293	Thioredoxin reductase 1, cytoplasmic	reviewed	-	Txnrd1	Potency	-	22387	nM
P00761	BXGT005645	Trypsin	reviewed	-		AC50	'='	9778	nM
Q96KQ7	BXGT019687	Histone-lysine N-methyltransferase EHMT2	reviewed	Epigenetic regulator	EHMT2	Potency	-	28183	nM
P08659	BXGT006805	Luciferin 4-monooxygenase	reviewed	-		Potency	-	26854	nM
Q9NR56	BXGT021179	Muscleblind-like protein 1	reviewed	Nucleic acid binding	MBNL1	Potency	-	39810	nM

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF00557	Black salsify	Scorzonera hispanica	Vegetables
BXGF00823	Fruits		Fruits
BXGF00875	Glycosmis pseudoracemosa	Glycosmis pseudoracemosa	Medicinal Plant
BXGF00929	Ficus conraui	Ficus conraui	Human Edible Plant
BXGF01005	Dictamnus dasycarpus	Dictamnus dasycarpus	Medicinal Plant
BXGF01063	Corydalis persica	Corydalis persica	Others
BXGF01067	Salta triflora	Salta triflora	Others
BXGF01119	Trapa japonica	Trapa japonica	Medicinal Plant
BXGF01136	Inula grantioides	Inula grantioides	Medicinal Plant
BXGF01152	Vernonia chloropappa	Vernonia chloropappa	Others
BXGF01339	Diospyros peregrina	Diospyros peregrina	Medicinal Plant
BXGF01363	Diospyros elliptifolia	Diospyros elliptifolia	Others
BXGF01395	Juniperus horizontalis	Juniperus horizontalis	Medicinal Plant
BXGF01445	Acronychia laurifolia	Acronychia laurifolia	Medicinal Plant
BXGF01525	Diospyros abyssinica	Diospyros abyssinica	Medicinal Plant
BXGF01572	Cratystylis conocephala	Cratystylis conocephala	Others
BXGF01577	Strychnos spinosa	Strychnos spinosa	Medicinal Plant
BXGF01579	Esenbeckia hartmanii	Esenbeckia hartmanii	Others
BXGF01587	Talipariti tiliaceum	Talipariti tiliaceum	Medicinal Plant
BXGF01645	Beaucarnea recurvata	Beaucarnea recurvata	Others
BXGF01714	Amomum daniellii	Amomum daniellii	Others
BXGF01730	Aeollanthus buchnerianus	Aeollanthus buchnerianus	Others
BXGF01852	Plectranthus caninus	Plectranthus caninus	Medicinal Plant
BXGF01935	Lathyrus tingitanus	Lathyrus tingitanus	Human Edible Plant
BXGF01969	Echium plantagineum	Echium plantagineum	Medicinal Plant
BXGF01970	Rauvolfia salicifolia	Rauvolfia salicifolia	Others
BXGF01990	Balanophora japonica	Balanophora japonica	Medicinal Plant
BXGF02070	Espeletiopsis purpurascens	Espeletiopsis purpurascens	Others
BXGF02252	Leptospermum recurvum	Leptospermum recurvum	Others
BXGF02350	Cota tinctoria	Cota tinctoria	Medicinal Plant
BXGF02424	Pycnarrhena australiana	Pycnarrhena australiana	Others
BXGF02480	Amomum reticulatum	Amomum reticulatum	Others
BXGF02577	Zanthoxylum planispinum	Zanthoxylum planispinum	Medicinal Plant
BXGF02629	Clausena vestita	Clausena vestita	Others
BXGF02746	Zanthoxylum avicennae	Zanthoxylum avicennae	Medicinal Plant
BXGF02804	Hernandia sonora	Hernandia sonora	Medicinal Plant
BXGF02838	Helianthus niveus	Helianthus niveus	Medicinal Plant
BXGF02933	Hosta sieboldiana	Hosta sieboldiana	Medicinal Plant
BXGF02969	Plectranthus hereroensis	Plectranthus hereroensis	Others
BXGF03031	Poa sphondylodes	Poa sphondylodes	Others
BXGF03227	Cynoglossum viridiflorum	Cynoglossum viridiflorum	Others
BXGF03254	Zanthoxylum integrifoliolum	Zanthoxylum integrifoliolum	Medicinal Plant
BXGF03427	Phellodendron chinense	Phellodendron chinense	Medicinal Plant
BXGF03433	Inula salsoloides	Inula salsoloides	Others
BXGF03557	Eutrochium purpureum	Eutrochium purpureum	Medicinal Plant
BXGF03625	Alchornea cordifolia	Alchornea cordifolia	Medicinal Plant
BXGF03639	Caralluma russeliana	Caralluma russeliana	Others
BXGF03657	Dalbergia monetaria	Dalbergia monetaria	Medicinal Plant
BXGF03676	Ursinia anthemoides	Ursinia anthemoides	Others
BXGF03682	Imperata cylindrica	Imperata cylindrica	Medicinal Plant
BXGF03694	Otholobium pubescens	Otholobium pubescens	Others
BXGF03706	Tetradium glabrifolium	Tetradium glabrifolium	Others
BXGF03716	Polypodium aureum	Polypodium aureum	Others
BXGF03733	Alpinia officinarum	Alpinia officinarum	Medicinal Plant
BXGF03756	Casimiroa edulis	Casimiroa edulis	Medicinal Plant
BXGF03792	Helianthus californicus	Helianthus californicus	Others
BXGF03828	Phellodendron amurense	Phellodendron amurense	Medicinal Plant
BXGF03829	Morinda coreia	Morinda coreia	Medicinal Plant
BXGF03909	Iris sanguinea	Iris sanguinea	Others
BXGF03914	Jacobaea cannabifolia	Jacobaea cannabifolia	Others
BXGF03960	Conium maculatum	Conium maculatum	Medicinal Plant
BXGF03979	Aglaia pyramidata	Aglaia pyramidata	Others
BXGF03992	Schrebera swietenoides	Schrebera swietenoides	Human Edible Plant
BXGF04008	Senecio gilliesi	Senecio gilliesi	Others
BXGF04020	Celastrus monospermus	Celastrus monospermus	Others
BXGF04078	Solanum spirale	Solanum spirale	Medicinal Plant
BXGF04101	Agave deserti	Agave deserti	Human Edible Plant
BXGF04111	Asclepias subulata	Asclepias subulata	Medicinal Plant
BXGF04201	Zanthoxylum simulans	Zanthoxylum simulans	Medicinal Plant
BXGF04256	Phellodendron chinese	Phellodendron chinese	Others
BXGF04354	Sophora leachiana	Sophora leachiana	Medicinal Plant
BXGF04382	Murraya paniculata	Murraya paniculata	Medicinal Plant
BXGF04412	Rhododendron edgeworthii	Rhododendron edgeworthii	Others
BXGF04443	Populus candicans	Populus candicans	Others
BXGF04655	Gutenbergia marginata	Gutenbergia marginata	Others
BXGF04670	Griselinia scandens	Griselinia scandens	Others
BXGF04684	Podocalyx loranthoides	Podocalyx loranthoides	Others
BXGF04702	Vernonia lilacina	Vernonia lilacina	Others
BXGF04703	Trixis grisebachii	Trixis grisebachii	Others
BXGF04721	Helicia erratica	Helicia erratica	Human Edible Plant
BXGF04774	Croton hutchinsonianus	Croton hutchinsonianus	Others
BXGF04790	Cicer cuneatum	Cicer cuneatum	Others
BXGF04803	Bulbine asphodeloides	Bulbine asphodeloides	Medicinal Plant
BXGF04805	Ipomoea carnea	Ipomoea carnea	Medicinal Plant
BXGF04810	Yucca elata	Yucca elata	Medicinal Plant
BXGF04828	Hyptis urticoides	Hyptis urticoides	Others
BXGF04833	Monachosorum maximowiczii	Monachosorum maximowiczii	Others
BXGF04888	Sarcophyton infundibuliforme	Sarcophyton infundibuliforme	Others
BXGF04895	Delphinium speciosum	Delphinium speciosum	Others
BXGF04899	Nardia scalaris	Nardia scalaris	Others
BXGF04929	Passiflora morifolia	Passiflora morifolia	Human Edible Plant
BXGF05082	Orixa japonica	Orixa japonica	Medicinal Plant
BXGF05111	Trifolium montanum	Trifolium montanum	Others
BXGF05165	Ruta graveolens	Ruta graveolens	Medicinal Plant
BXGF05186	Hortonia floribunda	Hortonia floribunda	Others
BXGF05188	Corynanthe pachyceras	Corynanthe pachyceras	Others
BXGF05331	Centaurea arenaria	Centaurea arenaria	Others
BXGF05386	Aegle marmelos	Aegle marmelos	Medicinal Plant
BXGF05455	Peucedanum oroselinum	Peucedanum oroselinum	Others
BXGF05463	Ageratina saltillensis	Ageratina saltillensis	Others
BXGF05471	Cynoglossum amabile	Cynoglossum amabile	Medicinal Plant
BXGF05549	Saussurea stella	Saussurea stella	Others
BXGF05598	Vicia balansae	Vicia balansae	Others
BXGF05638	Gutenbergia cordifolia	Gutenbergia cordifolia	Medicinal Plant
BXGF05660	Glycosmis cochinchinensis	Glycosmis cochinchinensis	Human Edible Plant
BXGF05746	Atalantia wightii	Atalantia wightii	Others
BXGF05797	Salvia polystachya	Salvia polystachya	Medicinal Plant
BXGF05827	Spiraea prunifolia	Spiraea prunifolia	Medicinal Plant
BXGF05939	Grewia villosa	Grewia villosa	Medicinal Plant
BXGF06136	Euonymus europaeus	Euonymus europaeus	Medicinal Plant
BXGF06143	Persicaria tinctoria	Persicaria tinctoria	Medicinal Plant
BXGF06247	Phyllodium pulchellum	Phyllodium pulchellum	Medicinal Plant
BXGF06286	Mikania scandens	Mikania scandens	Medicinal Plant
BXGF06326	Cotylelobium scabriusculum	Cotylelobium scabriusculum	Others

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}