Showing entry for (E)-Resveratrol


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0001767
Compound Name(E)-Resveratrol
Structure
FormulaC14H12O3
InchiKeyLUKBXSAWLPMMSZ-OWOJBTEDSA-N
SMILESOC1=CC=C(\C=C\C2=CC(O)=CC(O)=C2)C=C1
InchiInChI=1S/C14H12O3/c15-12-5-3-10(4-6-12)1-2-11-7-13(16)9-14(17)8-11/h1-9,15-17H/b2-1+
IUPAC5-[(E)-2-(4-hydroxyphenyl)ethenyl]benzene-1,3-diol
Molecular Weight228.25
Pubchem Id445154
Chembl IdCHEMBL165
Targets of Information Source
DrugBank DB02709
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
P16083 BXGT008187 Ribosyldihydronicotinamide dehydrogenase [quinone] reviewed - NQO2 investigational -
P68400 BXGT011599 Casein kinase II subunit alpha reviewed Kinase CSNK2A1 investigational -
P23219 BXGT008837 Prostaglandin G/H synthase 1 reviewed Enzyme PTGS1 investigational inhibitor
P35354 BXGT009816 Prostaglandin G/H synthase 2 reviewed Enzyme PTGS2 investigational inhibitor
P16050 BXGT008184 Arachidonate 15-lipoxygenase reviewed Enzyme ALOX15 investigational -
P09917 BXGT006941 Arachidonate 5-lipoxygenase reviewed Enzyme ALOX5 investigational -
P35869 BXGT009877 Aryl hydrocarbon receptor reviewed Transcription factor AHR investigational -
Q8TCG2 BXGT018798 Phosphatidylinositol 4-kinase type 2-beta reviewed Enzyme PI4K2B investigational -
P08648 BXGT006804 Integrin alpha-5 reviewed - ITGA5 investigational -
P05106 BXGT006315 Integrin beta-3 reviewed Receptor ITGB3 investigational -
P05067 BXGT006306 Amyloid-beta precursor protein reviewed Enzyme modulator APP investigational -
P37840 BXGT010015 Alpha-synuclein reviewed Transporter SNCA investigational -
Q96EB6 BXGT019646 NAD-dependent protein deacetylase sirtuin-1 reviewed Epigenetic regulator SIRT1 investigational -
P03372 BXGT006059 Estrogen receptor reviewed Nuclear receptor ESR1 investigational -
P48039 BXGT010607 Melatonin receptor type 1A reviewed G-protein coupled receptor MTNR1A investigational -
P49286 BXGT010691 Melatonin receptor type 1B reviewed G-protein coupled receptor MTNR1B investigational -
Q86T13 BXGT017603 C-type lectin domain family 14 member A reviewed - CLEC14A investigational -
O75469 BXGT005128 Nuclear receptor subfamily 1 group I member 2 reviewed Nuclear receptor NR1I2 investigational -
Q14994 BXGT013519 Nuclear receptor subfamily 1 group I member 3 reviewed Nuclear receptor NR1I3 investigational -
P11166 BXGT007661 Solute carrier family 2, facilitated glucose transporter member 1 reviewed Transporter SLC2A1 investigational -
P16152 BXGT008201 Carbonyl reductase [NADPH] 1 reviewed - CBR1 investigational inhibitor
Q07869 BXGT012945 Peroxisome proliferator-activated receptor alpha reviewed Nuclear receptor PPARA investigational -
P37231 BXGT009972 Peroxisome proliferator-activated receptor gamma reviewed Nuclear receptor PPARG investigational -
P31749 BXGT009574 RAC-alpha serine/threonine-protein kinase reviewed Kinase AKT1 investigational inhibitor
Q92945 BXGT019397 Far upstream element-binding protein 2 reviewed Enzyme KHSRP investigational -
P54577 BXGT011055 Tyrosine--tRNA ligase, cytoplasmic reviewed Enzyme YARS investigational inhibitor
PDB STL
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
P30074 BXGT009397 Chalcone synthase 2 reviewed CHS2 - - - - -
P02766 BXGT005953 Transthyretin reviewed TTR Transporter - - - -
P16083 BXGT008187 Ribosyldihydronicotinamide dehydrogenase [quinone] reviewed NQO2 - - - 35 -
Q9SLV5 BXGT021592 Resveratrol synthase unreviewed - - - - -
P05631 BXGT006372 ATP synthase subunit gamma, mitochondrial reviewed ATP5F1C - - - - -
P63316 BXGT011517 Troponin C, slow skeletal and cardiac muscles reviewed TNNC1 Calcium-binding protein - - - -
Q9NZL9 BXGT021277 Methionine adenosyltransferase 2 subunit beta reviewed MAT2B - - - - -
O43704 BXGT004615 Sulfotransferase family cytosolic 1B member 1 reviewed SULT1B1 - - - - -
P09960 BXGT006952 Leukotriene A-4 hydrolase reviewed LTA4H - - 212000 - -
P08799 BXGT006825 Myosin-2 heavy chain reviewed mhcA - - - - -
P81460 BXGT011951 Concanavalin-A reviewed - - - - -
Q9NXA8 BXGT021245 NAD-dependent protein deacylase sirtuin-5, mitochondrial reviewed SIRT5 Epigenetic regulator - - - -
P37231 BXGT009972 Peroxisome proliferator-activated receptor gamma reviewed PPARG Nuclear receptor - - - -
P03372 BXGT006059 Estrogen receptor reviewed ESR1 Nuclear receptor - - - -
P54577 BXGT011055 Tyrosine--tRNA ligase, cytoplasmic reviewed YARS1 Enzyme - - - -
P59071 BXGT011259 Basic phospholipase A2 VRV-PL-VIIIa reviewed - - - - -
P16083 BXGT008187 Ribosyldihydronicotinamide dehydrogenase [quinone] reviewed NQO2 - - - - -
Q96EB6 BXGT019646 NAD-dependent protein deacetylase sirtuin-1 reviewed SIRT1 Epigenetic regulator - - - -
Q2GA76 BXGT014069 Dioxygenase unreviewed Saro_0802 - - - - -
Q4QDU3 BXGT014873 UTP--glucose-1-phosphate uridylyltransferase unreviewed UGP - - - - -
Q7S860 BXGT017096 Carotenoid oxygenase 1 unreviewed cao-1 - - - - -
B5MGN7 BXGT024478 Glycosyltransferase unreviewed PaGT2 - - - - -
Binding DB 23926
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
reviewed BXGT003957 Aryl hydrocarbon receptor reviewed AHR 169 - - -
reviewed BXGT006059 Estrogen receptor reviewed Nuclear receptor ESR1 785 - - -
reviewed BXGT008187 Ribosyldihydronicotinamide dehydrogenase [quinone] reviewed NQO2 - 960 - -
reviewed BXGT012754 Transcription factor p65 reviewed Transcription factor RELA - - - 5203
reviewed BXGT022194 Zinc finger protein mex-5 reviewed mex-5 - - - 163131
reviewed BXGT006661 Cathepsin L1 reviewed Enzyme CTSL - >59642 - -
reviewed BXGT006016 Large T antigen reviewed - - 26200 - -
reviewed BXGT020189 Serine/threonine-protein kinase 33 reviewed Kinase STK33 - - - 12330
reviewed BXGT013656 Cytochrome P450 1B1 reviewed Enzyme CYP1B1 177 - - -
reviewed BXGT010983 Alpha-glucosidase MAL12 reviewed MAL12 21500 26400 - -
reviewed BXGT008837 Prostaglandin G/H synthase 1 reviewed Enzyme PTGS1 >10000 - - -
reviewed BXGT009816 Prostaglandin G/H synthase 2 reviewed Enzyme PTGS2 >10000 - - -
reviewed BXGT012754 Transcription factor p65 reviewed Transcription factor RELA - 20000 - -
reviewed BXGT007687 Tyrosinase reviewed Tyr - 10780 - -
reviewed BXGT006400 Prostaglandin G/H synthase 1 reviewed PTGS1 - 67300 - -
reviewed BXGT006400 Prostaglandin G/H synthase 1 reviewed PTGS1 - 2800 - -
reviewed BXGT006952 Leukotriene A-4 hydrolase reviewed LTA4H - 366000 - -
reviewed BXGT006805 Luciferin 4-monooxygenase reviewed - - 59 - -
reviewed BXGT007717 Aromatase reviewed Enzyme CYP19A1 - 25000 - -
reviewed BXGT006427 Tyrosine-protein kinase Lck reviewed Kinase LCK - 112000 - -
reviewed BXGT007687 Tyrosinase reviewed Tyr 2900000 - - -
reviewed BXGT007760 Ornithine decarboxylase reviewed Enzyme ODC1 - 19000 - -
reviewed BXGT008837 Prostaglandin G/H synthase 1 reviewed Enzyme PTGS1 - 195500 - -
reviewed BXGT008837 Prostaglandin G/H synthase 1 reviewed Enzyme PTGS1 - 2840 - -
reviewed BXGT008837 Prostaglandin G/H synthase 1 reviewed Enzyme PTGS1 - 830 - -
reviewed BXGT008187 Ribosyldihydronicotinamide dehydrogenase [quinone] reviewed NQO2 - 450 - -
reviewed BXGT008294 Protein kinase C alpha type reviewed Kinase PRKCA - - - 5780000
reviewed BXGT008930 Alpha-1D adrenergic receptor reviewed Adra1d - 19950 - -
reviewed BXGT011858 Prostaglandin G/H synthase 2 reviewed PTGS2 - 3490 - -
reviewed BXGT008837 Prostaglandin G/H synthase 1 reviewed Enzyme PTGS1 - 380 - -
reviewed BXGT009816 Prostaglandin G/H synthase 2 reviewed Enzyme PTGS2 - 33150 - -
reviewed BXGT004563 Polyphenol oxidase 2 reviewed PPO2 - 55610 - -
reviewed BXGT009816 Prostaglandin G/H synthase 2 reviewed Enzyme PTGS2 - 996 - -
reviewed BXGT006400 Prostaglandin G/H synthase 1 reviewed PTGS1 - 535 - -
reviewed BXGT009816 Prostaglandin G/H synthase 2 reviewed Enzyme PTGS2 - 990 - -
reviewed BXGT008369 Tyrosine-protein phosphatase non-receptor type 1 reviewed PTPN1 - >1000000 - -
reviewed BXGT016509 Transient receptor potential cation channel subfamily A member 1 reviewed Trpa1 - 19900 - -
reviewed BXGT016509 Transient receptor potential cation channel subfamily A member 1 reviewed Trpa1 - 750 - -
reviewed BXGT016509 Transient receptor potential cation channel subfamily A member 1 reviewed Trpa1 - 2740 - -
reviewed BXGT016509 Transient receptor potential cation channel subfamily A member 1 reviewed Trpa1 - 1400 - -
reviewed BXGT008187 Ribosyldihydronicotinamide dehydrogenase [quinone] reviewed NQO2 - 1400 - -
reviewed BXGT008187 Ribosyldihydronicotinamide dehydrogenase [quinone] reviewed NQO2 - 913 - -
reviewed BXGT006306 Amyloid-beta precursor protein reviewed Enzyme modulator APP - 4100 - -
reviewed BXGT006306 Amyloid-beta precursor protein reviewed Enzyme modulator APP - 2600 - -
reviewed BXGT006265 Cytochrome P450 1A1 reviewed Enzyme CYP1A1 - 34000 - -
reviewed BXGT013656 Cytochrome P450 1B1 reviewed Enzyme CYP1B1 - 55000 - -
reviewed BXGT006952 Leukotriene A-4 hydrolase reviewed LTA4H - 212000 - -
reviewed BXGT013624 Nuclear factor erythroid 2-related factor 2 reviewed Enzyme NFE2L2 - - - 5400
reviewed BXGT012941 Bcl-2-like protein 1 reviewed Signaling BCL2L1 - 190000 - -
reviewed BXGT009355 Nitric oxide synthase, inducible reviewed Nos2 - 15000 - -
reviewed BXGT009816 Prostaglandin G/H synthase 2 reviewed Enzyme PTGS2 - 750 - -
reviewed BXGT006400 Prostaglandin G/H synthase 1 reviewed PTGS1 - 6650 - -
reviewed BXGT008039 Tyrosinase reviewed Enzyme TYR - 3680000 - -
reviewed BXGT009301 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 reviewed Enzyme CD38 - >100000 - -
reviewed BXGT016460 Lysosomal alpha-glucosidase reviewed Gaa - >400000 - -
reviewed BXGT008901 Sucrase-isomaltase, intestinal reviewed Si - >400000 - -
reviewed BXGT006700 Aldo-keto reductase family 1 member B1 reviewed Akr1b1 - 25000 - -
reviewed BXGT007717 Aromatase reviewed Enzyme CYP19A1 41670 - - -
reviewed BXGT009355 Nitric oxide synthase, inducible reviewed Nos2 - 23200 - -
reviewed BXGT005570 Tyrosine-protein kinase ABL1 reviewed Kinase ABL1 - 28000 - -
reviewed BXGT006741 ATP-dependent translocase ABCB1 reviewed Transporter ABCB1 - 60000 - -
reviewed BXGT008837 Prostaglandin G/H synthase 1 reviewed Enzyme PTGS1 - 4120 - -
reviewed BXGT009816 Prostaglandin G/H synthase 2 reviewed Enzyme PTGS2 - 34610 - -
reviewed BXGT018362 NAD-dependent protein deacetylase sirtuin-2 reviewed Epigenetic regulator SIRT2 - - - >300000
reviewed BXGT021211 NAD-dependent protein deacetylase sirtuin-3, mitochondrial reviewed Epigenetic regulator SIRT3 - - - >300000
reviewed BXGT019646 NAD-dependent protein deacetylase sirtuin-1 reviewed Epigenetic regulator SIRT1 - - - 46200
reviewed BXGT009816 Prostaglandin G/H synthase 2 reviewed Enzyme PTGS2 - 32000 - -
reviewed BXGT006400 Prostaglandin G/H synthase 1 reviewed PTGS1 - - 11700 -
reviewed BXGT008837 Prostaglandin G/H synthase 1 reviewed Enzyme PTGS1 - 1100 - -
reviewed BXGT009816 Prostaglandin G/H synthase 2 reviewed Enzyme PTGS2 - 1300 - -
reviewed BXGT005690 Carbonic anhydrase 2 reviewed CA2 2770 - - -
reviewed BXGT006627 Carbonic anhydrase 3 reviewed CA3 9090 - - -
reviewed BXGT008802 Carbonic anhydrase 4 reviewed CA4 4470 - - -
reviewed BXGT009796 Carbonic anhydrase 5A, mitochondrial reviewed CA5A 4750 - - -
reviewed BXGT022229 Carbonic anhydrase 5B, mitochondrial reviewed CA5B 4640 - - -
reviewed BXGT008844 Carbonic anhydrase 6 reviewed CA6 8070 - - -
reviewed BXGT010364 Carbonic anhydrase 7 reviewed CA7 4350 - - -
reviewed BXGT013670 Carbonic anhydrase 9 reviewed CA9 810 - - -
reviewed BXGT004601 Carbonic anhydrase 12 reviewed CA12 950 - - -
reviewed BXGT018499 Carbonic anhydrase 13 reviewed CA13 4090 - - -
reviewed BXGT021769 Carbonic anhydrase 14 reviewed CA14 830 - - -
reviewed BXGT019994 Carbonic anhydrase 15 reviewed Ca15 9360 - - -
reviewed BXGT005689 Carbonic anhydrase 1 reviewed CA1 2210 - - -
reviewed BXGT019994 Carbonic anhydrase 15 reviewed Ca15 2570 - - -
reviewed BXGT005689 Carbonic anhydrase 1 reviewed CA1 2180 - - -
reviewed BXGT005690 Carbonic anhydrase 2 reviewed CA2 1750 - - -
reviewed BXGT013670 Carbonic anhydrase 9 reviewed CA9 9530 - - -
reviewed BXGT004601 Carbonic anhydrase 12 reviewed CA12 8130 - - -
reviewed BXGT006627 Carbonic anhydrase 3 reviewed CA3 6750 - - -
reviewed BXGT008802 Carbonic anhydrase 4 reviewed CA4 4010 - - -
reviewed BXGT022229 Carbonic anhydrase 5B, mitochondrial reviewed CA5B 3240 - - -
reviewed BXGT008844 Carbonic anhydrase 6 reviewed CA6 8630 - - -
reviewed BXGT010364 Carbonic anhydrase 7 reviewed CA7 8980 - - -
reviewed BXGT018499 Carbonic anhydrase 13 reviewed CA13 8250 - - -
reviewed BXGT021769 Carbonic anhydrase 14 reviewed CA14 1950 - - -
reviewed BXGT009796 Carbonic anhydrase 5A, mitochondrial reviewed CA5A 2860 - - -
reviewed BXGT007717 Aromatase reviewed Enzyme CYP19A1 - 25400 - -
reviewed BXGT006812 Cytochrome P450 3A4 reviewed Enzyme CYP3A4 20000 - - -
reviewed BXGT019646 NAD-dependent protein deacetylase sirtuin-1 reviewed Epigenetic regulator SIRT1 - - - 23600
reviewed BXGT005730 Myc proto-oncogene protein reviewed Transcription factor MYC - 60000 - -
reviewed BXGT008187 Ribosyldihydronicotinamide dehydrogenase [quinone] reviewed NQO2 - 6900 - -
reviewed BXGT008187 Ribosyldihydronicotinamide dehydrogenase [quinone] reviewed NQO2 88 - - -
reviewed BXGT008187 Ribosyldihydronicotinamide dehydrogenase [quinone] reviewed NQO2 - - 54 -
CHEMBL CHEMBL165
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
O42713 BXGT004563 Polyphenol oxidase 2 reviewed - PPO2 Inhibition '=' 13 %
O42713 BXGT004563 Polyphenol oxidase 2 reviewed - PPO2 Inhibition '=' 47 %
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 5011 nM
P27338 BXGT009172 Amine oxidase [flavin-containing] B reviewed - MAOB IC50 - - -
P00352 BXGT005510 Retinal dehydrogenase 1 reviewed Enzyme ALDH1A1 Potency '=' 31622 nM
Q9ULX7 BXGT021769 Carbonic anhydrase 14 reviewed - CA14 Ki '=' 830 nM
P05979 BXGT006400 Prostaglandin G/H synthase 1 reviewed - PTGS1 Activity - - -
P23219 BXGT008837 Prostaglandin G/H synthase 1 reviewed Enzyme PTGS1 IC50 '=' 1100 nM
P35354 BXGT009816 Prostaglandin G/H synthase 2 reviewed Enzyme PTGS2 IC50 '=' 1300 nM
Q64669 BXGT016128 NAD(P)H dehydrogenase [quinone] 1 reviewed - Nqo1 CD '=' 21 uM
P10275 BXGT007552 Androgen receptor reviewed Nuclear receptor AR Potency - 28183 nM
P51450 BXGT010847 Nuclear receptor ROR-gamma reviewed - Rorc Potency '=' 3981 nM
Q92731 BXGT019366 Estrogen receptor beta reviewed Nuclear receptor ESR2 Activity '=' 27 %
P25021 BXGT009004 Histamine H2 receptor reviewed G-protein coupled receptor HRH2 IC50 - - -
P03372 BXGT006059 Estrogen receptor reviewed Nuclear receptor ESR1 Potency - 35481 nM
P10275 BXGT007552 Androgen receptor reviewed Nuclear receptor AR Potency - 19952 nM
P32245 BXGT009614 Melanocortin receptor 4 reviewed G-protein coupled receptor MC4R Ki - - -
P21397 BXGT008644 Amine oxidase [flavin-containing] A reviewed - MAOA Ki - - -
P11229 BXGT007676 Muscarinic acetylcholine receptor M1 reviewed G-protein coupled receptor CHRM1 IC50 - - -
P08172 BXGT006737 Muscarinic acetylcholine receptor M2 reviewed G-protein coupled receptor CHRM2 IC50 - - -
P20309 BXGT008562 Muscarinic acetylcholine receptor M3 reviewed G-protein coupled receptor CHRM3 IC50 - - -
P20309 BXGT008562 Muscarinic acetylcholine receptor M3 reviewed G-protein coupled receptor CHRM3 Ki - - -
P08912 BXGT006840 Muscarinic acetylcholine receptor M5 reviewed G-protein coupled receptor CHRM5 IC50 - - -
P29477 BXGT009355 Nitric oxide synthase, inducible reviewed - Nos2 Ki - - -
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 Ki - - -
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 IC50 - - -
P28564 BXGT009272 5-hydroxytryptamine receptor 1B reviewed - Htr1b IC50 - - -
P28335 BXGT009255 5-hydroxytryptamine receptor 2C reviewed G-protein coupled receptor HTR2C Ki - - -
Q64669 BXGT016128 NAD(P)H dehydrogenase [quinone] 1 reviewed - Nqo1 Ratio '=' 2 -
O42713 BXGT004563 Polyphenol oxidase 2 reviewed - PPO2 Inhibition - - -
Q96QE3 BXGT019718 ATPase family AAA domain-containing protein 5 reviewed - ATAD5 Potency - 14581 nM
P08684 BXGT006812 Cytochrome P450 3A4 reviewed Enzyme CYP3A4 mechanism based inhibition - - -
Q64669 BXGT016128 NAD(P)H dehydrogenase [quinone] 1 reviewed - Nqo1 CD '>' 50 uM
P05067 BXGT006306 Amyloid-beta precursor protein reviewed Enzyme modulator APP Inhibition '=' 49 %
P11511 BXGT007717 Aromatase reviewed Enzyme CYP19A1 IC50 '=' 25000 nM
Q16678 BXGT013656 Cytochrome P450 1B1 reviewed Enzyme CYP1B1 Activity '=' 56 %
P29477 BXGT009355 Nitric oxide synthase, inducible reviewed - Nos2 Inhibition '=' 71 %
P00734 BXGT005630 Prothrombin reviewed Enzyme F2 Inhibition - - -
P05480 BXGT006364 Neuronal proto-oncogene tyrosine-protein kinase Src reviewed - Src Activity - - -
Q96EB6 BXGT019646 NAD-dependent protein deacetylase sirtuin-1 reviewed Epigenetic regulator SIRT1 Activity - - -
O42713 BXGT004563 Polyphenol oxidase 2 reviewed - PPO2 Inhibition '=' 16 %
P09960 BXGT006952 Leukotriene A-4 hydrolase reviewed - LTA4H IC50 '=' 366000 nM
P08912 BXGT006840 Muscarinic acetylcholine receptor M5 reviewed G-protein coupled receptor CHRM5 Ki - - -
P49146 BXGT010681 Neuropeptide Y receptor type 2 reviewed G-protein coupled receptor NPY2R IC50 - - -
P29476 BXGT009354 Nitric oxide synthase, brain reviewed - Nos1 Ki - - -
P18031 BXGT008369 Tyrosine-protein phosphatase non-receptor type 1 reviewed - PTPN1 IC50 '>' 1000000 nM
Q01158 BXGT012573 Luciferin 4-monooxygenase reviewed - Inhibition - - -
O75762 BXGT005151 Transient receptor potential cation channel subfamily A member 1 reviewed Ion channel TRPA1 Inhibition '=' 37 %
P22303 BXGT008751 Acetylcholinesterase reviewed Enzyme ACHE Inhibition - - -
P16083 BXGT008187 Ribosyldihydronicotinamide dehydrogenase [quinone] reviewed - NQO2 Ki '=' 88 nM
O15118 BXGT004127 NPC intracellular cholesterol transporter 1 reviewed Transporter NPC1 Potency '=' 18356 nM
P51450 BXGT010847 Nuclear receptor ROR-gamma reviewed - Rorc Potency '=' 14068 nM
P41595 BXGT010267 5-hydroxytryptamine receptor 2B reviewed G-protein coupled receptor HTR2B IC50 - - -
P05979 BXGT006400 Prostaglandin G/H synthase 1 reviewed - PTGS1 IC50 '=' 535 nM
P21397 BXGT008644 Amine oxidase [flavin-containing] A reviewed - MAOA Inhibition - - -
Q96EB6 BXGT019646 NAD-dependent protein deacetylase sirtuin-1 reviewed Epigenetic regulator SIRT1 Activity '=' 1 -
Q6RI86 BXGT016509 Transient receptor potential cation channel subfamily A member 1 reviewed - Trpa1 IC50 '=' 19900 nM
P04798 BXGT006265 Cytochrome P450 1A1 reviewed Enzyme CYP1A1 mechanism based inhibition - - -
Q13951 BXGT013407 Core-binding factor subunit beta reviewed - CBFB Potency - 28183 nM
Q01196 BXGT012575 Runt-related transcription factor 1 reviewed Transcription factor RUNX1 Potency - 28183 nM
Q9EQ79 BXGT020295 Alkaline phosphatase unreviewed - Activity - - -
P19785 BXGT008514 Estrogen receptor reviewed - Esr1 Activity - - -
Q16678 BXGT013656 Cytochrome P450 1B1 reviewed Enzyme CYP1B1 Ki '=' 800 nM
P28907 BXGT009301 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 reviewed Enzyme CD38 IC50 '>' 100000 nM
P21397 BXGT008644 Amine oxidase [flavin-containing] A reviewed - MAOA IC50 '=' 17410 nM
P81908 BXGT011959 Cholinesterase reviewed - BCHE IC50 '=' 752460 nM
Q99700 BXGT019949 Ataxin-2 reviewed Nucleic acid binding ATXN2 Potency - 6309 nM
P51151 BXGT010837 Ras-related protein Rab-9A reviewed - RAB9A Potency '=' 29092 nM
Q27686 BXGT013930 Pyruvate kinase reviewed - PYK Potency '=' 17782 nM
P00352 BXGT005510 Retinal dehydrogenase 1 reviewed Enzyme ALDH1A1 Potency '=' 39810 nM
O42713 BXGT004563 Polyphenol oxidase 2 reviewed - PPO2 IC50 '=' 55610 nM
P11511 BXGT007717 Aromatase reviewed Enzyme CYP19A1 Inhibition '=' 34 %
Q64669 BXGT016128 NAD(P)H dehydrogenase [quinone] 1 reviewed - Nqo1 Survival '=' 86 %
P27338 BXGT009172 Amine oxidase [flavin-containing] B reviewed - MAOB IC50 '=' 29370 nM
Q9NR56 BXGT021179 Muscleblind-like protein 1 reviewed Nucleic acid binding MBNL1 Potency - 39810 nM
P01106 BXGT005730 Myc proto-oncogene protein reviewed Transcription factor MYC IC50 '=' 60000 nM
B2RXH2 BXGT002006 Lysine-specific demethylase 4E reviewed - KDM4E Potency '=' 22387 nM
Q92887 BXGT019389 Canalicular multispecific organic anion transporter 1 reviewed Transporter ABCC2 Activity '=' 75 %
Q96EB6 BXGT019646 NAD-dependent protein deacetylase sirtuin-1 reviewed Epigenetic regulator SIRT1 EC50 '=' 46200 nM
Q96EB6 BXGT019646 NAD-dependent protein deacetylase sirtuin-1 reviewed Epigenetic regulator SIRT1 Activity '=' 201 %
P11167 BXGT007662 Solute carrier family 2, facilitated glucose transporter member 1 reviewed - Slc2a1 Activity - - -
P20781 BXGT008598 Glycine receptor subunit beta reviewed - Glrb Ki - - -
P07727 BXGT006662 Glycine receptor subunit alpha-1 reviewed - Glra1 Ki - - -
P24524 BXGT008974 Glycine receptor subunit alpha-3 reviewed - Glra3 Ki - - -
P22771 BXGT008806 Glycine receptor subunit alpha-2 reviewed - Glra2 Ki - - -
P05979 BXGT006400 Prostaglandin G/H synthase 1 reviewed - PTGS1 Kd '=' 11700 nM
P11511 BXGT007717 Aromatase reviewed Enzyme CYP19A1 IC50 '>' 40 ug.mL-1
O43524 BXGT004599 Forkhead box protein O3 reviewed - FOXO3 Activity - - -
P08684 BXGT006812 Cytochrome P450 3A4 reviewed Enzyme CYP3A4 Kinact '=' 0 min-1
P04637 BXGT006243 Cellular tumor antigen p53 reviewed Transcription factor TP53 Potency '=' 10000 nM
P09960 BXGT006952 Leukotriene A-4 hydrolase reviewed - LTA4H IC50 '=' 212000 nM
P07451 BXGT006627 Carbonic anhydrase 3 reviewed - CA3 Ki '=' 9090 nM
P29274 BXGT009327 Adenosine receptor A2a reviewed G-protein coupled receptor ADORA2A Ki - - -
P23975 BXGT008935 Sodium-dependent noradrenaline transporter reviewed Transporter SLC6A2 Ki '=' 2293 nM
P25025 BXGT009006 C-X-C chemokine receptor type 2 reviewed G-protein coupled receptor CXCR2 Ki - - -
P15127 BXGT008085 Insulin receptor reviewed - Insr Ki - - -
P12530 BXGT007827 Arachidonate 15-lipoxygenase reviewed - ALOX15 IC50 - - -
P35372 BXGT009823 Mu-type opioid receptor reviewed G-protein coupled receptor OPRM1 Ki - - -
P05067 BXGT006306 Amyloid-beta precursor protein reviewed Enzyme modulator APP Inhibition '=' 64 %
Q03431 BXGT012714 Parathyroid hormone/parathyroid hormone-related peptide receptor reviewed G-protein coupled receptor PTH1R Potency - 3981 nM
Q64669 BXGT016128 NAD(P)H dehydrogenase [quinone] 1 reviewed - Nqo1 Survival '=' 88 %
P05979 BXGT006400 Prostaglandin G/H synthase 1 reviewed - PTGS1 IC50 '=' 6650 nM
P31749 BXGT009574 RAC-alpha serine/threonine-protein kinase reviewed Kinase AKT1 Activity - - -
P11169 BXGT007664 Solute carrier family 2, facilitated glucose transporter member 3 reviewed Transporter SLC2A3 Activity - - -
Q96EB6 BXGT019646 NAD-dependent protein deacetylase sirtuin-1 reviewed Epigenetic regulator SIRT1 Activity '=' 250 %
Q9NPD5 BXGT021151 Solute carrier organic anion transporter family member 1B3 reviewed Transporter SLCO1B3 Inhibition '=' 116 %
P35354 BXGT009816 Prostaglandin G/H synthase 2 reviewed Enzyme PTGS2 IC50 '=' 750 nM
P29477 BXGT009355 Nitric oxide synthase, inducible reviewed - Nos2 IC50 '=' 15000 nM
O42713 BXGT004563 Polyphenol oxidase 2 reviewed - PPO2 Activity - - -
P22303 BXGT008751 Acetylcholinesterase reviewed Enzyme ACHE Ki - - -
P23975 BXGT008935 Sodium-dependent noradrenaline transporter reviewed Transporter SLC6A2 IC50 '=' 2312 nM
P50052 BXGT010768 Type-2 angiotensin II receptor reviewed G-protein coupled receptor AGTR2 IC50 - - -
P41597 BXGT010268 C-C chemokine receptor type 2 reviewed - CCR2 Ki - - -
P35354 BXGT009816 Prostaglandin G/H synthase 2 reviewed Enzyme PTGS2 IC50 - - -
P11509 BXGT007716 Cytochrome P450 2A6 reviewed - CYP2A6 Ki - - -
P33261 BXGT009707 Cytochrome P450 2C19 reviewed - CYP2C19 IC50 '=' 3000 nM
P25101 BXGT009018 Endothelin-1 receptor reviewed G-protein coupled receptor EDNRA IC50 - - -
Q9Y2D0 BXGT022229 Carbonic anhydrase 5B, mitochondrial reviewed - CA5B Ki '=' 4640 nM
P35354 BXGT009816 Prostaglandin G/H synthase 2 reviewed Enzyme PTGS2 IC50 '=' 32000 nM
P03956 BXGT006120 Interstitial collagenase reviewed Enzyme MMP1 IC50 - - -
P28482 BXGT009263 Mitogen-activated protein kinase 1 reviewed Kinase MAPK1 Ki - - -
P30542 BXGT009436 Adenosine receptor A1 reviewed G-protein coupled receptor ADORA1 IC50 - - -
P30542 BXGT009436 Adenosine receptor A1 reviewed G-protein coupled receptor ADORA1 Ki - - -
P07943 BXGT006700 Aldo-keto reductase family 1 member B1 reviewed - Akr1b1 Ki - - -
P21554 BXGT008662 Cannabinoid receptor 1 reviewed G-protein coupled receptor CNR1 IC50 - - -
P03372 BXGT006059 Estrogen receptor reviewed Nuclear receptor ESR1 Ki - - -
P32241 BXGT009613 Vasoactive intestinal polypeptide receptor 1 reviewed G-protein coupled receptor VIPR1 Ki - - -
P10636 BXGT007596 Microtubule-associated protein tau reviewed - MAPT Potency '=' 10000 nM
P08684 BXGT006812 Cytochrome P450 3A4 reviewed Enzyme CYP3A4 Potency '=' 3981 nM
O15118 BXGT004127 NPC intracellular cholesterol transporter 1 reviewed Transporter NPC1 Potency '=' 5623 nM
P00352 BXGT005510 Retinal dehydrogenase 1 reviewed Enzyme ALDH1A1 Potency '=' 35481 nM
P41968 BXGT010275 Melanocortin receptor 3 reviewed G-protein coupled receptor MC3R IC50 - - -
P21728 BXGT008686 D(1A) dopamine receptor reviewed G-protein coupled receptor DRD1 Ki - - -
P35462 BXGT009835 D(3) dopamine receptor reviewed G-protein coupled receptor DRD3 IC50 - - -
Q01959 BXGT012624 Sodium-dependent dopamine transporter reviewed Transporter SLC6A3 IC50 - - -
P15823 BXGT008160 Alpha-1B adrenergic receptor reviewed - Adra1b Ki - - -
P25100 BXGT009017 Alpha-1D adrenergic receptor reviewed G-protein coupled receptor ADRA1D Ki - - -
P08588 BXGT006795 Beta-1 adrenergic receptor reviewed G-protein coupled receptor ADRB1 Ki - - -
P07550 BXGT006636 Beta-2 adrenergic receptor reviewed G-protein coupled receptor ADRB2 IC50 - - -
P41597 BXGT010268 C-C chemokine receptor type 2 reviewed - CCR2 IC50 - - -
P51151 BXGT010837 Ras-related protein Rab-9A reviewed - RAB9A Potency '=' 3981 nM
P10636 BXGT007596 Microtubule-associated protein tau reviewed - MAPT Potency '=' 7079 nM
Q01453 BXGT012588 Peripheral myelin protein 22 reviewed Cellular structure PMP22 Potency '=' 42561 nM
O15296 BXGT004148 Arachidonate 15-lipoxygenase B reviewed Enzyme ALOX15B Potency - 19952 nM
Q9Y271 BXGT022222 Cysteinyl leukotriene receptor 1 reviewed G-protein coupled receptor CYSLTR1 Ki - - -
P25929 BXGT009078 Neuropeptide Y receptor type 1 reviewed G-protein coupled receptor NPY1R IC50 - - -
O76074 BXGT005174 cGMP-specific 3',5'-cyclic phosphodiesterase reviewed - PDE5A IC50 - - -
O76074 BXGT005174 cGMP-specific 3',5'-cyclic phosphodiesterase reviewed - PDE5A Ki - - -
P12822 BXGT007850 Angiotensin-converting enzyme reviewed - ACE IC50 - - -
P04626 BXGT006238 Receptor tyrosine-protein kinase erbB-2 reviewed Kinase ERBB2 IC50 - - -
P10636 BXGT007596 Microtubule-associated protein tau reviewed - MAPT Potency '=' 8912 nM
G5EF15 BXGT003524 Cytoplasmic zinc-finger protein unreviewed - pos-1 EC50 '>' 300000 nM
P05067 BXGT006306 Amyloid-beta precursor protein reviewed Enzyme modulator APP Inhibition '=' 63 %
P37231 BXGT009972 Peroxisome proliferator-activated receptor gamma reviewed Nuclear receptor PPARG Potency - 35481 nM
P28223 BXGT009239 5-hydroxytryptamine receptor 2A reviewed G-protein coupled receptor HTR2A Ki - - -
O70528 BXGT005068 5-hydroxytryptamine receptor 4 reviewed - HTR4 Ki - - -
P18089 BXGT008379 Alpha-2B adrenergic receptor reviewed G-protein coupled receptor ADRA2B IC50 - - -
P18825 BXGT008426 Alpha-2C adrenergic receptor reviewed G-protein coupled receptor ADRA2C Ki - - -
P13945 BXGT007972 Beta-3 adrenergic receptor reviewed G-protein coupled receptor ADRB3 IC50 - - -
P30411 BXGT009424 B2 bradykinin receptor reviewed G-protein coupled receptor BDKRB2 Ki - - -
P32238 BXGT009611 Cholecystokinin receptor type A reviewed G-protein coupled receptor CCKAR Ki - - -
P05177 BXGT006336 Cytochrome P450 1A2 reviewed Enzyme CYP1A2 Ki - - -
P10635 BXGT007595 Cytochrome P450 2D6 reviewed - CYP2D6 Ki - - -
P25101 BXGT009018 Endothelin-1 receptor reviewed G-protein coupled receptor EDNRA Ki - - -
O89049 BXGT005293 Thioredoxin reductase 1, cytoplasmic reviewed - Txnrd1 Potency - 18887 nM
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 IC50 - - -
Q690N0 BXGT016199 Progesterone receptor unreviewed - PGR IC50 - - -
P05067 BXGT006306 Amyloid-beta precursor protein reviewed Enzyme modulator APP Activity - - -
P00352 BXGT005510 Retinal dehydrogenase 1 reviewed Enzyme ALDH1A1 Potency '=' 22387 nM
P03372 BXGT006059 Estrogen receptor reviewed Nuclear receptor ESR1 Potency - 31622 nM
P97697 BXGT012214 Inositol monophosphatase 1 reviewed - Impa1 Potency '=' 10000 nM
Q16637 BXGT013646 Survival motor neuron protein reviewed Epigenetic regulator SMN1 Potency '=' 35481 nM
Q9JKS8 BXGT020831 Alkaline phosphatase unreviewed - Akp3 Activity - - -
P35367 BXGT009821 Histamine H1 receptor reviewed G-protein coupled receptor HRH1 Ki - - -
P11274 BXGT007681 Breakpoint cluster region protein reviewed Enzyme modulator BCR AC50 '>' 100000 nM
P00519 BXGT005570 Tyrosine-protein kinase ABL1 reviewed Kinase ABL1 AC50 '>' 100000 nM
P06239 BXGT006427 Tyrosine-protein kinase Lck reviewed Kinase LCK IC50 '=' 112000 nM
P03372 BXGT006059 Estrogen receptor reviewed Nuclear receptor ESR1 Potency - 7079 nM
P79208 BXGT011858 Prostaglandin G/H synthase 2 reviewed - PTGS2 IC50 '=' 3490 nM
P23219 BXGT008837 Prostaglandin G/H synthase 1 reviewed Enzyme PTGS1 IC50 '=' 2840 nM
P35869 BXGT009877 Aryl hydrocarbon receptor reviewed Transcription factor AHR Ratio - - -
Q12809 BXGT013267 Potassium voltage-gated channel subfamily H member 2 reviewed Ion channel KCNH2 IC50 - - -
P29477 BXGT009355 Nitric oxide synthase, inducible reviewed - Nos2 IC50 '=' 23200 nM
P02545 BXGT005889 Prelamin-A/C reviewed - LMNA Potency '=' 5 nM
P16083 BXGT008187 Ribosyldihydronicotinamide dehydrogenase [quinone] reviewed - NQO2 IC50 '=' 960 nM
P10828 BXGT007624 Thyroid hormone receptor beta reviewed Nuclear receptor THRB Potency '=' 112201 nM
P02768 BXGT005955 Serum albumin reviewed Transporter ALB Ka - - -
Q99N23 BXGT019994 Carbonic anhydrase 15 reviewed - Ca15 Ki '=' 9360 nM
Q99714 BXGT019954 3-hydroxyacyl-CoA dehydrogenase type-2 reviewed Enzyme HSD17B10 Potency '=' 39810 nM
Q96EB6 BXGT019646 NAD-dependent protein deacetylase sirtuin-1 reviewed Epigenetic regulator SIRT1 EC1.5 '=' 46 uM
P05979 BXGT006400 Prostaglandin G/H synthase 1 reviewed - PTGS1 Activity '=' 47 %
P35869 BXGT009877 Aryl hydrocarbon receptor reviewed Transcription factor AHR Activity '=' 1 %
P06746 BXGT006496 DNA polymerase beta reviewed Enzyme POLB Potency '=' 44668 nM
P00918 BXGT005690 Carbonic anhydrase 2 reviewed - CA2 Ki '=' 2770 nM
Q8N1Q1 BXGT018499 Carbonic anhydrase 13 reviewed - CA13 Ki '=' 4090 nM
P79208 BXGT011858 Prostaglandin G/H synthase 2 reviewed - PTGS2 Selectivity index '=' 0 -
P05979 BXGT006400 Prostaglandin G/H synthase 1 reviewed - PTGS1 Selectivity index '=' 0 -
Q8IXJ6 BXGT018362 NAD-dependent protein deacetylase sirtuin-2 reviewed Epigenetic regulator SIRT2 EC50 '>' 300000 nM
Q96EB6 BXGT019646 NAD-dependent protein deacetylase sirtuin-1 reviewed Epigenetic regulator SIRT1 Activity '=' 1 -
P15428 BXGT008121 15-hydroxyprostaglandin dehydrogenase [NAD(+)] reviewed - HPGD Potency '=' 25118 nM
P35354 BXGT009816 Prostaglandin G/H synthase 2 reviewed Enzyme PTGS2 IC50 '=' 34610 nM
P17252 BXGT008294 Protein kinase C alpha type reviewed Kinase PRKCA EC50 '=' 5780000 nM
P03372 BXGT006059 Estrogen receptor reviewed Nuclear receptor ESR1 Ki '=' 785 nM
Q12778 BXGT013263 Forkhead box protein O1 reviewed - FOXO1 Inhibition '<' 40 %
Q8I2J3 BXGT018207 M18 aspartyl aminopeptidase unreviewed - PF3D7_0932300 IC50 '=' 2242 nM
Q99714 BXGT019954 3-hydroxyacyl-CoA dehydrogenase type-2 reviewed Enzyme HSD17B10 Potency '=' 31622 nM
P05067 BXGT006306 Amyloid-beta precursor protein reviewed Enzyme modulator APP IC50 '=' 15110 nM
Q96EB6 BXGT019646 NAD-dependent protein deacetylase sirtuin-1 reviewed Epigenetic regulator SIRT1 Activity '=' 1 -
P02545 BXGT005889 Prelamin-A/C reviewed - LMNA Potency '=' 35481 nM
O75874 BXGT005157 Isocitrate dehydrogenase [NADP] cytoplasmic reviewed - IDH1 Potency - 32642 nM
P35354 BXGT009816 Prostaglandin G/H synthase 2 reviewed Enzyme PTGS2 IC50 '=' 33150 nM
P10636 BXGT007596 Microtubule-associated protein tau reviewed - MAPT Potency '=' 5623 nM
P08183 BXGT006741 ATP-dependent translocase ABCB1 reviewed Transporter ABCB1 AC50 '>' 100000 nM
P02545 BXGT005889 Prelamin-A/C reviewed - LMNA Potency '=' 12589 nM
P10636 BXGT007596 Microtubule-associated protein tau reviewed - MAPT Potency '=' 15848 nM
P02768 BXGT005955 Serum albumin reviewed Transporter ALB Ka '=' 1 10'5/M
P23219 BXGT008837 Prostaglandin G/H synthase 1 reviewed Enzyme PTGS1 IC50 '=' 195500 nM
Q9FBZ2 BXGT020360 Prenyltransferase homolog unreviewed - SCO7190 Km '=' 440000 nM
P51450 BXGT010847 Nuclear receptor ROR-gamma reviewed - Rorc Potency '=' 14125 nM
P10636 BXGT007596 Microtubule-associated protein tau reviewed - MAPT Potency '=' 12589 nM
P43166 BXGT010364 Carbonic anhydrase 7 reviewed - CA7 Ki '=' 4350 nM
P10636 BXGT007596 Microtubule-associated protein tau reviewed - MAPT Potency '=' 17782 nM
O42713 BXGT004563 Polyphenol oxidase 2 reviewed - PPO2 Inhibition '=' 20 %
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 10000 nM
Q01959 BXGT012624 Sodium-dependent dopamine transporter reviewed Transporter SLC6A3 Ki - - -
P00811 BXGT005666 Beta-lactamase reviewed - ampC Potency '=' 44668 nM
P41968 BXGT010275 Melanocortin receptor 3 reviewed G-protein coupled receptor MC3R Ki - - -
P08173 BXGT006738 Muscarinic acetylcholine receptor M4 reviewed G-protein coupled receptor CHRM4 Ki - - -
P29477 BXGT009355 Nitric oxide synthase, inducible reviewed - Nos2 IC50 - - -
P25105 BXGT009021 Platelet-activating factor receptor reviewed G-protein coupled receptor PTAFR Ki - - -
P23739 BXGT008901 Sucrase-isomaltase, intestinal reviewed - Si IC50 '>' 400000 nM
B2RXH2 BXGT002006 Lysine-specific demethylase 4E reviewed - KDM4E Potency '=' 25118 nM
O42713 BXGT004563 Polyphenol oxidase 2 reviewed - PPO2 Inhibition '=' 90 %
P35354 BXGT009816 Prostaglandin G/H synthase 2 reviewed Enzyme PTGS2 IC50 '=' 996 nM
Q16637 BXGT013646 Survival motor neuron protein reviewed Epigenetic regulator SMN1 Potency '=' 12589 nM
Q9FBZ2 BXGT020360 Prenyltransferase homolog unreviewed - SCO7190 Kcat '=' 0 10'3/s
P11274 BXGT007681 Breakpoint cluster region protein reviewed Enzyme modulator BCR IC50 '=' 28000 nM
P00519 BXGT005570 Tyrosine-protein kinase ABL1 reviewed Kinase ABL1 IC50 '=' 28000 nM
P08684 BXGT006812 Cytochrome P450 3A4 reviewed Enzyme CYP3A4 Ki '=' 20000 nM
P09217 BXGT006872 Protein kinase C zeta type reviewed - Prkcz IC50 '=' 40 ug.mL-1
Q9WTQ0 BXGT021929 Protein kinase C theta type reviewed - Prkcq IC50 '=' 40 ug.mL-1
Q64617 BXGT016127 Protein kinase C eta type reviewed - Prkch IC50 '=' 40 ug.mL-1
P09215 BXGT006870 Protein kinase C delta type reviewed - Prkcd IC50 '=' 40 ug.mL-1
P63319 BXGT011518 Protein kinase C gamma type reviewed - Prkcg IC50 '=' 40 ug.mL-1
P09216 BXGT006871 Protein kinase C epsilon type reviewed - Prkce IC50 '=' 40 ug.mL-1
P68403 BXGT011600 Protein kinase C beta type reviewed - Prkcb IC50 '=' 40 ug.mL-1
P05696 BXGT006379 Protein kinase C alpha type reviewed - Prkca IC50 '=' 40 ug.mL-1
P03372 BXGT006059 Estrogen receptor reviewed Nuclear receptor ESR1 Potency - 10000 nM
P11511 BXGT007717 Aromatase reviewed Enzyme CYP19A1 IC50 - - -
Q9FBZ2 BXGT020360 Prenyltransferase homolog unreviewed - SCO7190 Ratio '=' 0 -
P04798 BXGT006265 Cytochrome P450 1A1 reviewed Enzyme CYP1A1 IC50 '=' 34000 nM
P07711 BXGT006661 Cathepsin L1 reviewed Enzyme CTSL IC50 '>' 59642 nM
P08659 BXGT006805 Luciferin 4-monooxygenase reviewed - Potency '=' 5011 nM
Q64669 BXGT016128 NAD(P)H dehydrogenase [quinone] 1 reviewed - Nqo1 Activity '>' 20 uM
Q6RI86 BXGT016509 Transient receptor potential cation channel subfamily A member 1 reviewed - Trpa1 Efficacy '<' 10 %
O60341 BXGT004873 Lysine-specific histone demethylase 1A reviewed Epigenetic regulator KDM1A IC50 '=' 10200 nM
P05067 BXGT006306 Amyloid-beta precursor protein reviewed Enzyme modulator APP Inhibition '=' 61 %
P04150 BXGT006154 Glucocorticoid receptor reviewed Nuclear receptor NR3C1 Potency - 28183 nM
P11712 BXGT007738 Cytochrome P450 2C9 reviewed - CYP2C9 Ki - - -
P06239 BXGT006427 Tyrosine-protein kinase Lck reviewed Kinase LCK Ki - - -
P24557 BXGT008976 Thromboxane-A synthase reviewed - TBXAS1 IC50 - - -
P50406 BXGT010796 5-hydroxytryptamine receptor 6 reviewed G-protein coupled receptor HTR6 IC50 - - -
P37231 BXGT009972 Peroxisome proliferator-activated receptor gamma reviewed Nuclear receptor PPARG Potency - 31622 nM
Q6RI86 BXGT016509 Transient receptor potential cation channel subfamily A member 1 reviewed - Trpa1 IC50 '=' 2740 nM
O43570 BXGT004601 Carbonic anhydrase 12 reviewed - CA12 Ki '=' 950 nM
P03372 BXGT006059 Estrogen receptor reviewed Nuclear receptor ESR1 Activity - - -
P14679 BXGT008039 Tyrosinase reviewed Enzyme TYR Inhibition '=' 36 %
P49798 BXGT010745 Regulator of G-protein signaling 4 reviewed Enzyme modulator RGS4 Potency - 15003 nM
P25100 BXGT009017 Alpha-1D adrenergic receptor reviewed G-protein coupled receptor ADRA1D IC50 - - -
P08588 BXGT006795 Beta-1 adrenergic receptor reviewed G-protein coupled receptor ADRB1 IC50 - - -
P13945 BXGT007972 Beta-3 adrenergic receptor reviewed G-protein coupled receptor ADRB3 Ki - - -
P05181 BXGT006337 Cytochrome P450 2E1 reviewed - CYP2E1 Ki - - -
B2RXH2 BXGT002006 Lysine-specific demethylase 4E reviewed - KDM4E Potency '=' 39810 nM
P10275 BXGT007552 Androgen receptor reviewed Nuclear receptor AR Potency - 12589 nM
P11021 BXGT007644 Endoplasmic reticulum chaperone BiP reviewed - HSPA5 Potency - 130 nM
P15207 BXGT008096 Androgen receptor reviewed - Ar Ki - - -
P42345 BXGT010304 Serine/threonine-protein kinase mTOR reviewed Kinase MTOR Potency '=' 3689 nM
P23739 BXGT008901 Sucrase-isomaltase, intestinal reviewed - Si Inhibition '=' 35 %
P11511 BXGT007717 Aromatase reviewed Enzyme CYP19A1 Ki '=' 41670 nM
Q96KQ7 BXGT019687 Histone-lysine N-methyltransferase EHMT2 reviewed Epigenetic regulator EHMT2 Potency - 7943 nM
P04150 BXGT006154 Glucocorticoid receptor reviewed Nuclear receptor NR3C1 IC50 - - -
P08311 BXGT006762 Cathepsin G reviewed Enzyme CTSG Ki - - -
P06241 BXGT006429 Tyrosine-protein kinase Fyn reviewed Kinase FYN Ki - - -
P28564 BXGT009272 5-hydroxytryptamine receptor 1B reviewed - Htr1b Ki - - -
Q08209 BXGT012968 Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform reviewed - PPP3CA IC50 - - -
P19327 BXGT008472 5-hydroxytryptamine receptor 1A reviewed - Htr1a Ki - - -
Q16637 BXGT013646 Survival motor neuron protein reviewed Epigenetic regulator SMN1 Potency '=' 8912 nM
P08659 BXGT006805 Luciferin 4-monooxygenase reviewed - Inhibition '=' 6 %
Q96EB6 BXGT019646 NAD-dependent protein deacetylase sirtuin-1 reviewed Epigenetic regulator SIRT1 EC50 '=' 23600 nM
Q49PX0 BXGT014770 N1L unreviewed - VACV_BRZ_SERRO2_026 IC50 '=' 21900 nM
Q49PX0 BXGT014770 N1L unreviewed - VACV_BRZ_SERRO2_026 Tm '=' 54 degrees C
Q6P7A9 BXGT016460 Lysosomal alpha-glucosidase reviewed - Gaa Inhibition '=' 36 %
Q92731 BXGT019366 Estrogen receptor beta reviewed Nuclear receptor ESR2 Activity - - -
P27695 BXGT009199 DNA-(apurinic or apyrimidinic site) lyase reviewed - APEX1 Potency - 35481 nM
P35354 BXGT009816 Prostaglandin G/H synthase 2 reviewed Enzyme PTGS2 IC50 '=' 990 nM
P04150 BXGT006154 Glucocorticoid receptor reviewed Nuclear receptor NR3C1 Potency - 35481 nM
P05979 BXGT006400 Prostaglandin G/H synthase 1 reviewed - PTGS1 IC50 '=' 380 nM
P27487 BXGT009187 Dipeptidyl peptidase 4 reviewed Enzyme DPP4 IC50 '=' 0 nM
Q02769 BXGT012668 Squalene synthase reviewed - Fdft1 IC50 '>' 50000 nM
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 18837 nM
P05067 BXGT006306 Amyloid-beta precursor protein reviewed Enzyme modulator APP IC50 '=' 11890 nM
Q12809 BXGT013267 Potassium voltage-gated channel subfamily H member 2 reviewed Ion channel KCNH2 Ki - - -
P11509 BXGT007716 Cytochrome P450 2A6 reviewed - CYP2A6 IC50 - - -
O75762 BXGT005151 Transient receptor potential cation channel subfamily A member 1 reviewed Ion channel TRPA1 Inhibition '=' -3 %
P16083 BXGT008187 Ribosyldihydronicotinamide dehydrogenase [quinone] reviewed - NQO2 IC50 '=' 450 nM
P03372 BXGT006059 Estrogen receptor reviewed Nuclear receptor ESR1 FC '=' 0 -
Q92731 BXGT019366 Estrogen receptor beta reviewed Nuclear receptor ESR2 FC '=' 0 -
P23219 BXGT008837 Prostaglandin G/H synthase 1 reviewed Enzyme PTGS1 IC50 '=' 4120 nM
Q99549 BXGT019932 M-phase phosphoprotein 8 reviewed Epigenetic regulator MPHOSPH8 Potency - 158 nM
P35456 BXGT009834 Urokinase plasminogen activator surface receptor reviewed - Plaur Potency - 20749 nM
P20918 BXGT008615 Plasminogen reviewed - Plg Potency - 20749 nM
P06869 BXGT006517 Urokinase-type plasminogen activator reviewed - Plau Potency - 20749 nM
P05067 BXGT006306 Amyloid-beta precursor protein reviewed Enzyme modulator APP Inhibition '=' 57 %
Q64669 BXGT016128 NAD(P)H dehydrogenase [quinone] 1 reviewed - Nqo1 Ratio '=' 0 -
P15428 BXGT008121 15-hydroxyprostaglandin dehydrogenase [NAD(+)] reviewed - HPGD Potency '=' 10000 nM
P35218 BXGT009796 Carbonic anhydrase 5A, mitochondrial reviewed - CA5A Ki '=' 4750 nM
P07943 BXGT006700 Aldo-keto reductase family 1 member B1 reviewed - Akr1b1 IC50 '=' 25000 nM
P05979 BXGT006400 Prostaglandin G/H synthase 1 reviewed - PTGS1 IC50 '=' 67300 nM
P23219 BXGT008837 Prostaglandin G/H synthase 1 reviewed Enzyme PTGS1 Activity - - -
P05979 BXGT006400 Prostaglandin G/H synthase 1 reviewed - PTGS1 Inhibition '=' 75 %
P11511 BXGT007717 Aromatase reviewed Enzyme CYP19A1 Imax '=' 67 %
Q862F3 BXGT017581 Similar to alpha-tubulin isoform 1 unreviewed - IC50 '>' 40000 nM
Q862L2 BXGT017582 Similar to alpha-tubulin isoform 1 unreviewed - IC50 '>' 40000 nM
Q6B856 BXGT016212 Tubulin beta-2B chain reviewed - TUBB2B IC50 '>' 40000 nM
P42858 BXGT010341 Huntingtin reviewed - HTT Potency '=' 2238 nM
Q9NTG7 BXGT021211 NAD-dependent protein deacetylase sirtuin-3, mitochondrial reviewed Epigenetic regulator SIRT3 EC50 '>' 300000 nM
P18825 BXGT008426 Alpha-2C adrenergic receptor reviewed G-protein coupled receptor ADRA2C IC50 - - -
P51681 BXGT010878 C-C chemokine receptor type 5 reviewed G-protein coupled receptor CCR5 IC50 - - -
P21917 BXGT008707 D(4) dopamine receptor reviewed G-protein coupled receptor DRD4 Ki - - -
P51450 BXGT010847 Nuclear receptor ROR-gamma reviewed - Rorc Potency '=' 10000 nM
P23944 BXGT008930 Alpha-1D adrenergic receptor reviewed - Adra1d IC50 '=' 19950 nM
Q99720 BXGT019955 Sigma non-opioid intracellular receptor 1 reviewed - SIGMAR1 IC50 - - -
P21452 BXGT008653 Substance-K receptor reviewed G-protein coupled receptor TACR2 IC50 - - -
P37288 BXGT009977 Vasopressin V1a receptor reviewed G-protein coupled receptor AVPR1A Ki - - -
P11926 BXGT007760 Ornithine decarboxylase reviewed Enzyme ODC1 IC50 '=' 19000 nM
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 21136 nM
O42275 BXGT004559 Acetylcholinesterase reviewed - ache IC50 '=' 165240 nM
Q96EB6 BXGT019646 NAD-dependent protein deacetylase sirtuin-1 reviewed Epigenetic regulator SIRT1 Activity '=' 48 uM
Q6P7A9 BXGT016460 Lysosomal alpha-glucosidase reviewed - Gaa IC50 '>' 400000 nM
Q49PX0 BXGT014770 N1L unreviewed - VACV_BRZ_SERRO2_026 Activity - - -
Q07817 BXGT012941 Bcl-2-like protein 1 reviewed Signaling BCL2L1 IC50 '=' 190000 nM
O75496 BXGT005132 Geminin reviewed - GMNN Potency - 29092 nM
P54132 BXGT011032 Bloom syndrome protein reviewed - BLM Potency '=' 50118 nM
P51450 BXGT010847 Nuclear receptor ROR-gamma reviewed - Rorc Potency '=' 1995 nM
P51450 BXGT010847 Nuclear receptor ROR-gamma reviewed - Rorc Potency '=' 1778 nM
Q96EB6 BXGT019646 NAD-dependent protein deacetylase sirtuin-1 reviewed Epigenetic regulator SIRT1 max activation '=' 200 %
P30988 BXGT009491 Calcitonin receptor reviewed G-protein coupled receptor CALCR Ki - - -
Q92731 BXGT019366 Estrogen receptor beta reviewed Nuclear receptor ESR2 IC50 - - -
Q92731 BXGT019366 Estrogen receptor beta reviewed Nuclear receptor ESR2 Ki - - -
P35367 BXGT009821 Histamine H1 receptor reviewed G-protein coupled receptor HRH1 IC50 - - -
P32241 BXGT009613 Vasoactive intestinal polypeptide receptor 1 reviewed G-protein coupled receptor VIPR1 IC50 - - -
P43140 BXGT010360 Alpha-1A adrenergic receptor reviewed - Adra1a Ki - - -
P07943 BXGT006700 Aldo-keto reductase family 1 member B1 reviewed - Akr1b1 IC50 - - -
P25024 BXGT009005 C-X-C chemokine receptor type 1 reviewed G-protein coupled receptor CXCR1 Ki - - -
P23219 BXGT008837 Prostaglandin G/H synthase 1 reviewed Enzyme PTGS1 IC50 '=' 625 nM
P11712 BXGT007738 Cytochrome P450 2C9 reviewed - CYP2C9 IC50 '=' 7000 nM
P29466 BXGT009349 Caspase-1 reviewed Enzyme CASP1 IC50 - - -
P27361 BXGT009176 Mitogen-activated protein kinase 3 reviewed Kinase MAPK3 IC50 - - -
P37288 BXGT009977 Vasopressin V1a receptor reviewed G-protein coupled receptor AVPR1A IC50 - - -
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 reviewed Enzyme NFE2L2 Potency - 37578 nM
Q04206 BXGT012754 Transcription factor p65 reviewed Transcription factor RELA EC50 '=' 5203 nM
P19838 BXGT008526 Nuclear factor NF-kappa-B p105 subunit reviewed Transcription factor NFKB1 EC50 '=' 5203 nM
Q00653 BXGT012541 Nuclear factor NF-kappa-B p100 subunit reviewed Transcription factor NFKB2 EC50 '=' 5203 nM
Q96EB6 BXGT019646 NAD-dependent protein deacetylase sirtuin-1 reviewed Epigenetic regulator SIRT1 Activity '=' 1 -
O42713 BXGT004563 Polyphenol oxidase 2 reviewed - PPO2 Inhibition '=' 47 %
P51449 BXGT010846 Nuclear receptor ROR-gamma reviewed Nuclear receptor RORC Potency - 2371 nM
P05067 BXGT006306 Amyloid-beta precursor protein reviewed Enzyme modulator APP Inhibition '=' 78 %
P35354 BXGT009816 Prostaglandin G/H synthase 2 reviewed Enzyme PTGS2 Inhibition '=' 72 %
P43220 BXGT010367 Glucagon-like peptide 1 receptor reviewed G-protein coupled receptor GLP1R Potency - 28183 nM
P16083 BXGT008187 Ribosyldihydronicotinamide dehydrogenase [quinone] reviewed - NQO2 IC50 '=' 913 nM
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform reviewed Kinase PIK3CA IC50 '=' 250 nM
P42338 BXGT010303 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform reviewed Kinase PIK3CB IC50 '=' 500 nM
P15428 BXGT008121 15-hydroxyprostaglandin dehydrogenase [NAD(+)] reviewed - HPGD Potency '=' 14125 nM
Q92731 BXGT019366 Estrogen receptor beta reviewed Nuclear receptor ESR2 RBA '=' 0 -
P10253 BXGT007550 Lysosomal alpha-glucosidase reviewed Enzyme GAA Potency '=' 39506 nM
Q96EB6 BXGT019646 NAD-dependent protein deacetylase sirtuin-1 reviewed Epigenetic regulator SIRT1 Activity '=' 1 -
O42275 BXGT004559 Acetylcholinesterase reviewed - ache Inhibition '=' 15 %
P12530 BXGT007827 Arachidonate 15-lipoxygenase reviewed - ALOX15 Ki - - -
P25105 BXGT009021 Platelet-activating factor receptor reviewed G-protein coupled receptor PTAFR IC50 - - -
P08246 BXGT006756 Neutrophil elastase reviewed Enzyme ELANE IC50 - - -
Q08209 BXGT012968 Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform reviewed - PPP3CA Ki - - -
P08246 BXGT006756 Neutrophil elastase reviewed Enzyme ELANE Ki - - -
P21728 BXGT008686 D(1A) dopamine receptor reviewed G-protein coupled receptor DRD1 IC50 - - -
P25024 BXGT009005 C-X-C chemokine receptor type 1 reviewed G-protein coupled receptor CXCR1 IC50 - - -
Q03164 BXGT012700 Histone-lysine N-methyltransferase 2A reviewed - KMT2A Potency '=' 12589 nM
O00255 BXGT003903 Menin reviewed - MEN1 Potency '=' 12589 nM
P04637 BXGT006243 Cellular tumor antigen p53 reviewed Transcription factor TP53 Potency '=' 6309 nM
P00915 BXGT005689 Carbonic anhydrase 1 reviewed - CA1 Ki '=' 2210 nM
P23280 BXGT008844 Carbonic anhydrase 6 reviewed - CA6 Ki '=' 8070 nM
Q16665 BXGT013653 Hypoxia-inducible factor 1-alpha reviewed Transcription factor HIF1A Potency '=' 10000 nM
B2RXH2 BXGT002006 Lysine-specific demethylase 4E reviewed - KDM4E Potency '=' 31622 nM
O42275 BXGT004559 Acetylcholinesterase reviewed - ache IC50 '>' 1000000 nM
P11511 BXGT007717 Aromatase reviewed Enzyme CYP19A1 Inhibition '=' 63 %
Q96QE3 BXGT019718 ATPase family AAA domain-containing protein 5 reviewed - ATAD5 Potency - 6510 nM
P23219 BXGT008837 Prostaglandin G/H synthase 1 reviewed Enzyme PTGS1 Selectivity index '=' 0 -
P35354 BXGT009816 Prostaglandin G/H synthase 2 reviewed Enzyme PTGS2 Selectivity index '=' 0 -
P08183 BXGT006741 ATP-dependent translocase ABCB1 reviewed Transporter ABCB1 IC50 '=' 60000 nM
P10636 BXGT007596 Microtubule-associated protein tau reviewed - MAPT Potency '=' 22387 nM
Q16637 BXGT013646 Survival motor neuron protein reviewed Epigenetic regulator SMN1 Potency '=' 14125 nM
Q96EB6 BXGT019646 NAD-dependent protein deacetylase sirtuin-1 reviewed Epigenetic regulator SIRT1 Activity '=' 1 -
P05067 BXGT006306 Amyloid-beta precursor protein reviewed Enzyme modulator APP IC50 '=' 1100 nM
P05067 BXGT006306 Amyloid-beta precursor protein reviewed Enzyme modulator APP Inhibition '=' 42 %
P08913 BXGT006841 Alpha-2A adrenergic receptor reviewed G-protein coupled receptor ADRA2A IC50 - - -
P50052 BXGT010768 Type-2 angiotensin II receptor reviewed G-protein coupled receptor AGTR2 Ki - - -
P21554 BXGT008662 Cannabinoid receptor 1 reviewed G-protein coupled receptor CNR1 Ki - - -
P00918 BXGT005690 Carbonic anhydrase 2 reviewed - CA2 IC50 - - -
P51679 BXGT010877 C-C chemokine receptor type 4 reviewed G-protein coupled receptor CCR4 IC50 - - -
Q03181 BXGT012701 Peroxisome proliferator-activated receptor delta reviewed Nuclear receptor PPARD Potency - 31622 nM
P14679 BXGT008039 Tyrosinase reviewed Enzyme TYR IC50 '=' 3680000 nM
P05067 BXGT006306 Amyloid-beta precursor protein reviewed Enzyme modulator APP IC50 '=' 4100 nM
P17252 BXGT008294 Protein kinase C alpha type reviewed Kinase PRKCA Activity '=' 60 %
P05067 BXGT006306 Amyloid-beta precursor protein reviewed Enzyme modulator APP IC50 '=' 2600 nM
P11511 BXGT007717 Aromatase reviewed Enzyme CYP19A1 IC50 '=' 25400 nM
P35354 BXGT009816 Prostaglandin G/H synthase 2 reviewed Enzyme PTGS2 Ki - - -
P04035 BXGT006129 3-hydroxy-3-methylglutaryl-coenzyme A reductase reviewed - HMGCR Ki - - -
P41143 BXGT010223 Delta-type opioid receptor reviewed G-protein coupled receptor OPRD1 IC50 - - -
P08311 BXGT006762 Cathepsin G reviewed Enzyme CTSG IC50 - - -
P05067 BXGT006306 Amyloid-beta precursor protein reviewed Enzyme modulator APP Flu intensity '=' 294 -
P05067 BXGT006306 Amyloid-beta precursor protein reviewed Enzyme modulator APP Kd '=' 38500 nM
P08659 BXGT006805 Luciferin 4-monooxygenase reviewed - IC50 '=' 58 nM
Q03164 BXGT012700 Histone-lysine N-methyltransferase 2A reviewed - KMT2A Potency '=' 39810 nM
O00255 BXGT003903 Menin reviewed - MEN1 Potency '=' 39810 nM
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 reviewed Enzyme NFE2L2 Potency - 5804 nM
P51450 BXGT010847 Nuclear receptor ROR-gamma reviewed - Rorc Potency '=' 2511 nM
P11344 BXGT007687 Tyrosinase reviewed - Tyr Ki '=' 2900000 nM
P51450 BXGT010847 Nuclear receptor ROR-gamma reviewed - Rorc Potency '=' 3965 nM
P04150 BXGT006154 Glucocorticoid receptor reviewed Nuclear receptor NR3C1 Ki - - -
P12822 BXGT007850 Angiotensin-converting enzyme reviewed - ACE Ki - - -
P17252 BXGT008294 Protein kinase C alpha type reviewed Kinase PRKCA IC50 - - -
P00533 BXGT005575 Epidermal growth factor receptor reviewed Kinase EGFR Ki - - -
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 16360 nM
P08659 BXGT006805 Luciferin 4-monooxygenase reviewed - Potency - 1901 nM
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 reviewed Enzyme NFE2L2 Potency - 19331 nM
P16083 BXGT008187 Ribosyldihydronicotinamide dehydrogenase [quinone] reviewed - NQO2 Kd '=' 54 nM
P28482 BXGT009263 Mitogen-activated protein kinase 1 reviewed Kinase MAPK1 IC50 - - -
P81908 BXGT011959 Cholinesterase reviewed - BCHE Inhibition '=' 36 %
O42713 BXGT004563 Polyphenol oxidase 2 reviewed - PPO2 Inhibition '=' 27 %
O70528 BXGT005068 5-hydroxytryptamine receptor 4 reviewed - HTR4 IC50 - - -
P31645 BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 IC50 - - -
P25103 BXGT009020 Substance-P receptor reviewed G-protein coupled receptor TACR1 Ki - - -
P15207 BXGT008096 Androgen receptor reviewed - Ar IC50 - - -
P17948 BXGT008358 Vascular endothelial growth factor receptor 1 reviewed Kinase FLT1 IC50 - - -
P0DMS8 BXGT007506 Adenosine receptor A3 reviewed G-protein coupled receptor ADORA3 IC50 - - -
P25025 BXGT009006 C-X-C chemokine receptor type 2 reviewed G-protein coupled receptor CXCR2 IC50 - - -
P33261 BXGT009707 Cytochrome P450 2C19 reviewed - CYP2C19 Ki - - -
O42713 BXGT004563 Polyphenol oxidase 2 reviewed - PPO2 Inhibition '=' 38 %
P30988 BXGT009491 Calcitonin receptor reviewed G-protein coupled receptor CALCR IC50 - - -
P51681 BXGT010878 C-C chemokine receptor type 5 reviewed G-protein coupled receptor CCR5 Ki - - -
P08684 BXGT006812 Cytochrome P450 3A4 reviewed Enzyme CYP3A4 Ki - - -
P29274 BXGT009327 Adenosine receptor A2a reviewed G-protein coupled receptor ADORA2A IC50 - - -
P0DMS8 BXGT007506 Adenosine receptor A3 reviewed G-protein coupled receptor ADORA3 Ki - - -
P30411 BXGT009424 B2 bradykinin receptor reviewed G-protein coupled receptor BDKRB2 IC50 - - -
P11021 BXGT007644 Endoplasmic reticulum chaperone BiP reviewed - HSPA5 Potency - 1166 nM
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 9200 nM
P01106 BXGT005730 Myc proto-oncogene protein reviewed Transcription factor MYC MED '=' 55 uM
Q6RI86 BXGT016509 Transient receptor potential cation channel subfamily A member 1 reviewed - Trpa1 IC50 '=' 1400 nM
P22748 BXGT008802 Carbonic anhydrase 4 reviewed - CA4 Ki '=' 4470 nM
P17252 BXGT008294 Protein kinase C alpha type reviewed Kinase PRKCA Inhibition '=' 5 %
P17252 BXGT008294 Protein kinase C alpha type reviewed Kinase PRKCA Activity - - -
P15289 BXGT008102 Arylsulfatase A reviewed Enzyme ARSA Potency - 379 nM
Q03181 BXGT012701 Peroxisome proliferator-activated receptor delta reviewed Nuclear receptor PPARD Potency - 35481 nM
P05979 BXGT006400 Prostaglandin G/H synthase 1 reviewed - PTGS1 IC50 '=' 2800 nM
Q16678 BXGT013656 Cytochrome P450 1B1 reviewed Enzyme CYP1B1 IC50 '=' 55000 nM
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 reviewed Enzyme NFE2L2 FC '=' 3 -
P38398 BXGT010037 Breast cancer type 1 susceptibility protein reviewed Enzyme BRCA1 Potency - 12589 nM
Q96EB6 BXGT019646 NAD-dependent protein deacetylase sirtuin-1 reviewed Epigenetic regulator SIRT1 Ratio EC50 '=' 2 -
P21917 BXGT008707 D(4) dopamine receptor reviewed G-protein coupled receptor DRD4 IC50 - - -
P28223 BXGT009239 5-hydroxytryptamine receptor 2A reviewed G-protein coupled receptor HTR2A IC50 - - -
P32238 BXGT009611 Cholecystokinin receptor type A reviewed G-protein coupled receptor CCKAR IC50 - - -
P05177 BXGT006336 Cytochrome P450 1A2 reviewed Enzyme CYP1A2 IC50 '=' 3000 nM
P41145 BXGT010225 Kappa-type opioid receptor reviewed G-protein coupled receptor OPRK1 Ki - - -
Q690N0 BXGT016199 Progesterone receptor unreviewed - PGR Ki - - -
P14780 BXGT008053 Matrix metalloproteinase-9 reviewed Enzyme MMP9 IC50 - - -
P17252 BXGT008294 Protein kinase C alpha type reviewed Kinase PRKCA Ki - - -
Q16539 BXGT013634 Mitogen-activated protein kinase 14 reviewed Kinase MAPK14 IC50 - - -
Q16539 BXGT013634 Mitogen-activated protein kinase 14 reviewed Kinase MAPK14 Ki - - -
P18089 BXGT008379 Alpha-2B adrenergic receptor reviewed G-protein coupled receptor ADRA2B Ki - - -
P03372 BXGT006059 Estrogen receptor reviewed Nuclear receptor ESR1 RBA '=' 0 -
P32245 BXGT009614 Melanocortin receptor 4 reviewed G-protein coupled receptor MC4R IC50 - - -
P08575 BXGT006793 Receptor-type tyrosine-protein phosphatase C reviewed Enzyme PTPRC Ki - - -
P19327 BXGT008472 5-hydroxytryptamine receptor 1A reviewed - Htr1a IC50 - - -
P03372 BXGT006059 Estrogen receptor reviewed Nuclear receptor ESR1 IC50 - - -
P11229 BXGT007676 Muscarinic acetylcholine receptor M1 reviewed G-protein coupled receptor CHRM1 Ki - - -
P80244 BXGT011887 ATP-dependent Clp protease proteolytic subunit reviewed - clpP Potency - 25118 nM
P03070 BXGT006016 Large T antigen reviewed - IC50 - 26200 nM
Q9NZ45 BXGT021269 CDGSH iron-sulfur domain-containing protein 1 reviewed - CISD1 Inhibition - - -
P05067 BXGT006306 Amyloid-beta precursor protein reviewed Enzyme modulator APP Inhibition '=' 45 %
P37231 BXGT009972 Peroxisome proliferator-activated receptor gamma reviewed Nuclear receptor PPARG Potency - 17782 nM
P05067 BXGT006306 Amyloid-beta precursor protein reviewed Enzyme modulator APP Inhibition '=' 69 %
P05067 BXGT006306 Amyloid-beta precursor protein reviewed Enzyme modulator APP Activity '=' 24 %
P22303 BXGT008751 Acetylcholinesterase reviewed Enzyme ACHE IC50 '>' 5000 nM
P08913 BXGT006841 Alpha-2A adrenergic receptor reviewed G-protein coupled receptor ADRA2A Ki - - -
P51679 BXGT010877 C-C chemokine receptor type 4 reviewed G-protein coupled receptor CCR4 Ki - - -
P05067 BXGT006306 Amyloid-beta precursor protein reviewed Enzyme modulator APP Inhibition '=' 63 %
Q16790 BXGT013670 Carbonic anhydrase 9 reviewed - CA9 Ki '=' 810 nM
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 8052 nM
Q96EB6 BXGT019646 NAD-dependent protein deacetylase sirtuin-1 reviewed Epigenetic regulator SIRT1 max activation '=' 802 %
P05067 BXGT006306 Amyloid-beta precursor protein reviewed Enzyme modulator APP IC50 '=' 15900 nM
Q03164 BXGT012700 Histone-lysine N-methyltransferase 2A reviewed - KMT2A Potency '=' 22387 nM
O00255 BXGT003903 Menin reviewed - MEN1 Potency '=' 22387 nM
Q64669 BXGT016128 NAD(P)H dehydrogenase [quinone] 1 reviewed - Nqo1 Ratio '=' 1 -
A6XA80 BXGT001522 Leukotriene C4 synthase reviewed - LTC4S Ki - - -
P08172 BXGT006737 Muscarinic acetylcholine receptor M2 reviewed G-protein coupled receptor CHRM2 Ki - - -
P49146 BXGT010681 Neuropeptide Y receptor type 2 reviewed G-protein coupled receptor NPY2R Ki - - -
P29476 BXGT009354 Nitric oxide synthase, brain reviewed - Nos1 IC50 - - -
P04626 BXGT006238 Receptor tyrosine-protein kinase erbB-2 reviewed Kinase ERBB2 Ki - - -
P35462 BXGT009835 D(3) dopamine receptor reviewed G-protein coupled receptor DRD3 Ki - - -
P10635 BXGT007595 Cytochrome P450 2D6 reviewed - CYP2D6 IC50 - - -
P41595 BXGT010267 5-hydroxytryptamine receptor 2B reviewed G-protein coupled receptor HTR2B Ki - - -
P42345 BXGT010304 Serine/threonine-protein kinase mTOR reviewed Kinase MTOR Potency '=' 18492 nM
P25103 BXGT009020 Substance-P receptor reviewed G-protein coupled receptor TACR1 IC50 - - -
Q9UBT6 BXGT021664 DNA polymerase kappa reviewed - POLK Potency - 14125 nM
P08659 BXGT006805 Luciferin 4-monooxygenase reviewed - Inhibition '=' 99 %
A6XA80 BXGT001522 Leukotriene C4 synthase reviewed - LTC4S IC50 - - -
P28335 BXGT009255 5-hydroxytryptamine receptor 2C reviewed G-protein coupled receptor HTR2C IC50 - - -
P50406 BXGT010796 5-hydroxytryptamine receptor 6 reviewed G-protein coupled receptor HTR6 Ki - - -
Q99720 BXGT019955 Sigma non-opioid intracellular receptor 1 reviewed - SIGMAR1 Ki - - -
P24557 BXGT008976 Thromboxane-A synthase reviewed - TBXAS1 Ki - - -
O75762 BXGT005151 Transient receptor potential cation channel subfamily A member 1 reviewed Ion channel TRPA1 IC50 '=' 750 nM
P29477 BXGT009355 Nitric oxide synthase, inducible reviewed - Nos2 Inhibition '=' 86 %
O02747 BXGT003957 Aryl hydrocarbon receptor reviewed - AHR Ki '=' 169 nM
P83916 BXGT012025 Chromobox protein homolog 1 reviewed Epigenetic regulator CBX1 Potency - 0 nM
P81908 BXGT011959 Cholinesterase reviewed - BCHE IC50 - - -
P23219 BXGT008837 Prostaglandin G/H synthase 1 reviewed Enzyme PTGS1 IC50 '=' 830 nM
Q9XUB2 BXGT022194 Zinc finger protein mex-5 reviewed - mex-5 EC50 '=' 163131 nM
Q08499 BXGT012988 cAMP-specific 3',5'-cyclic phosphodiesterase 4D reviewed - PDE4D IC50 - - -
P22303 BXGT008751 Acetylcholinesterase reviewed Enzyme ACHE Inhibition '=' 1 %
P02766 BXGT005953 Transthyretin reviewed Transporter TTR Activity '=' 9 %
P04798 BXGT006265 Cytochrome P450 1A1 reviewed Enzyme CYP1A1 Activity '=' 11 %
O60341 BXGT004873 Lysine-specific histone demethylase 1A reviewed Epigenetic regulator KDM1A Inhibition - - -
Q96EB6 BXGT019646 NAD-dependent protein deacetylase sirtuin-1 reviewed Epigenetic regulator SIRT1 Inhibition - - -
P31645 BXGT009558 Sodium-dependent serotonin transporter reviewed Transporter SLC6A4 Ki - - -
P14416 BXGT008011 D(2) dopamine receptor reviewed G-protein coupled receptor DRD2 IC50 - - -
P20781 BXGT008598 Glycine receptor subunit beta reviewed - Glrb IC50 - - -
P07727 BXGT006662 Glycine receptor subunit alpha-1 reviewed - Glra1 IC50 - - -
P24524 BXGT008974 Glycine receptor subunit alpha-3 reviewed - Glra3 IC50 - - -
P22771 BXGT008806 Glycine receptor subunit alpha-2 reviewed - Glra2 IC50 - - -
P25021 BXGT009004 Histamine H2 receptor reviewed G-protein coupled receptor HRH2 Ki - - -
P04035 BXGT006129 3-hydroxy-3-methylglutaryl-coenzyme A reductase reviewed - HMGCR IC50 - - -
P33032 BXGT009689 Melanocortin receptor 5 reviewed G-protein coupled receptor MC5R IC50 - - -
Q96QE3 BXGT019718 ATPase family AAA domain-containing protein 5 reviewed - ATAD5 Potency - 2908 nM
P14780 BXGT008053 Matrix metalloproteinase-9 reviewed Enzyme MMP9 Ki - - -
P06241 BXGT006429 Tyrosine-protein kinase Fyn reviewed Kinase FYN IC50 - - -
P03956 BXGT006120 Interstitial collagenase reviewed Enzyme MMP1 Ki - - -
P08575 BXGT006793 Receptor-type tyrosine-protein phosphatase C reviewed Enzyme PTPRC IC50 - - -
O42713 BXGT004563 Polyphenol oxidase 2 reviewed - PPO2 Inhibition '=' 10 %
Q96EB6 BXGT019646 NAD-dependent protein deacetylase sirtuin-1 reviewed Epigenetic regulator SIRT1 max activation '=' 239 %
P06276 BXGT006430 Cholinesterase reviewed - BCHE Inhibition - - -
P06276 BXGT006430 Cholinesterase reviewed - BCHE Inhibition '=' 0 %
P51450 BXGT010847 Nuclear receptor ROR-gamma reviewed - Rorc Potency '=' 25118 nM
P00918 BXGT005690 Carbonic anhydrase 2 reviewed - CA2 Ki - - -
Q9Y271 BXGT022222 Cysteinyl leukotriene receptor 1 reviewed G-protein coupled receptor CYSLTR1 IC50 - - -
P00533 BXGT005575 Epidermal growth factor receptor reviewed Kinase EGFR IC50 - - -
P06239 BXGT006427 Tyrosine-protein kinase Lck reviewed Kinase LCK IC50 - - -
P43140 BXGT010360 Alpha-1A adrenergic receptor reviewed - Adra1a IC50 - - -
P55789 BXGT011126 FAD-linked sulfhydryl oxidase ALR reviewed Enzyme GFER AC50 '=' 4021 nM
Q8WZA2 BXGT019025 Rap guanine nucleotide exchange factor 4 reviewed Enzyme modulator RAPGEF4 Potency - 19952 nM
Q96QE3 BXGT019718 ATPase family AAA domain-containing protein 5 reviewed - ATAD5 Potency - 4109 nM
P05067 BXGT006306 Amyloid-beta precursor protein reviewed Enzyme modulator APP Activity '=' 61 %
Q96EB6 BXGT019646 NAD-dependent protein deacetylase sirtuin-1 reviewed Epigenetic regulator SIRT1 EC50 '=' 87200 nM
Q04206 BXGT012754 Transcription factor p65 reviewed Transcription factor RELA IC50 '=' 2500 nM
P19838 BXGT008526 Nuclear factor NF-kappa-B p105 subunit reviewed Transcription factor NFKB1 IC50 '=' 2500 nM
Q00653 BXGT012541 Nuclear factor NF-kappa-B p100 subunit reviewed Transcription factor NFKB2 IC50 '=' 2500 nM
O42713 BXGT004563 Polyphenol oxidase 2 reviewed - PPO2 IC50 '=' 26630 nM
P05067 BXGT006306 Amyloid-beta precursor protein reviewed Enzyme modulator APP Activity '=' 86 %
P22303 BXGT008751 Acetylcholinesterase reviewed Enzyme ACHE IC50 - - -
P05181 BXGT006337 Cytochrome P450 2E1 reviewed - CYP2E1 IC50 - - -
P05067 BXGT006306 Amyloid-beta precursor protein reviewed Enzyme modulator APP Activity '=' 108 %
P06276 BXGT006430 Cholinesterase reviewed - BCHE IC50 '>' 5000 nM
P05067 BXGT006306 Amyloid-beta precursor protein reviewed Enzyme modulator APP Inhibition - - -
P56817 BXGT011200 Beta-secretase 1 reviewed Enzyme BACE1 Inhibition '=' 41 %
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 12762 nM
P35869 BXGT009877 Aryl hydrocarbon receptor reviewed Transcription factor AHR Potency - 17782 nM
O14746 BXGT004091 Telomerase reverse transcriptase reviewed Enzyme TERT IC50 '=' 85000 nM
P08173 BXGT006738 Muscarinic acetylcholine receptor M4 reviewed G-protein coupled receptor CHRM4 IC50 - - -
P04637 BXGT006243 Cellular tumor antigen p53 reviewed Transcription factor TP53 Potency - 50118 nM
P10696 BXGT007603 Alkaline phosphatase, germ cell type reviewed Enzyme ALPG Activity - - -
P05067 BXGT006306 Amyloid-beta precursor protein reviewed Enzyme modulator APP Activity '=' 100 %
Q9UNA4 BXGT021785 DNA polymerase iota reviewed - POLI Potency - 44668 nM
Q99700 BXGT019949 Ataxin-2 reviewed Nucleic acid binding ATXN2 Potency - 35481 nM
P35869 BXGT009877 Aryl hydrocarbon receptor reviewed Transcription factor AHR Potency - 25118 nM
P15127 BXGT008085 Insulin receptor reviewed - Insr IC50 - - -
P17948 BXGT008358 Vascular endothelial growth factor receptor 1 reviewed Kinase FLT1 Ki - - -
P33032 BXGT009689 Melanocortin receptor 5 reviewed G-protein coupled receptor MC5R Ki - - -
P21397 BXGT008644 Amine oxidase [flavin-containing] A reviewed - MAOA IC50 '=' 449 nM
P25929 BXGT009078 Neuropeptide Y receptor type 1 reviewed G-protein coupled receptor NPY1R Ki - - -
P21452 BXGT008653 Substance-K receptor reviewed G-protein coupled receptor TACR2 Ki - - -
P29466 BXGT009349 Caspase-1 reviewed Enzyme CASP1 Ki - - -
P08684 BXGT006812 Cytochrome P450 3A4 reviewed Enzyme CYP3A4 IC50 '=' 600 nM
P05067 BXGT006306 Amyloid-beta precursor protein reviewed Enzyme modulator APP Inhibition '=' 68 %
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 8199 nM
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 reviewed Enzyme NFE2L2 Potency - 5955 nM
P05067 BXGT006306 Amyloid-beta precursor protein reviewed Enzyme modulator APP Activity '=' 4 %
P51450 BXGT010847 Nuclear receptor ROR-gamma reviewed - Rorc Potency '=' 35481 nM
P02766 BXGT005953 Transthyretin reviewed Transporter TTR Inhibition '=' 94 %
P05067 BXGT006306 Amyloid-beta precursor protein reviewed Enzyme modulator APP Flu intensity '=' 113 -
Q92731 BXGT019366 Estrogen receptor beta reviewed Nuclear receptor ESR2 FC '=' 1 -
P16083 BXGT008187 Ribosyldihydronicotinamide dehydrogenase [quinone] reviewed - NQO2 IC50 '=' 6900 nM
Q04206 BXGT012754 Transcription factor p65 reviewed Transcription factor RELA IC50 '=' 20000 nM
P05067 BXGT006306 Amyloid-beta precursor protein reviewed Enzyme modulator APP Inhibition '=' 61 %
O15648 BXGT004185 ATP-dependent 6-phosphofructokinase reviewed - pfk Potency - 9528 nM
O75762 BXGT005151 Transient receptor potential cation channel subfamily A member 1 reviewed Ion channel TRPA1 EC50 '>' 30000 nM
P81908 BXGT011959 Cholinesterase reviewed - BCHE IC50 '=' 400000 nM
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 reviewed Enzyme NFE2L2 Potency - 4855 nM
P80457 BXGT011911 Xanthine dehydrogenase/oxidase reviewed - XDH IC50 - - -
P16083 BXGT008187 Ribosyldihydronicotinamide dehydrogenase [quinone] reviewed - NQO2 IC50 '=' 1400 nM
O42275 BXGT004559 Acetylcholinesterase reviewed - ache IC50 - - -
Q6RI86 BXGT016509 Transient receptor potential cation channel subfamily A member 1 reviewed - Trpa1 IC50 '=' 750 nM
P15428 BXGT008121 15-hydroxyprostaglandin dehydrogenase [NAD(+)] reviewed - HPGD Potency '=' 31622 nM
P05067 BXGT006306 Amyloid-beta precursor protein reviewed Enzyme modulator APP Inhibition '=' 80 %
P05067 BXGT006306 Amyloid-beta precursor protein reviewed Enzyme modulator APP Inhibition '=' 39 %
P02766 BXGT005953 Transthyretin reviewed Transporter TTR Activity '=' 28 %
O75762 BXGT005151 Transient receptor potential cation channel subfamily A member 1 reviewed Ion channel TRPA1 FC '=' 0 -
Q16678 BXGT013656 Cytochrome P450 1B1 reviewed Enzyme CYP1B1 Ki '=' 11200 nM
O89049 BXGT005293 Thioredoxin reductase 1, cytoplasmic reviewed - Txnrd1 Potency - 23778 nM
P35354 BXGT009816 Prostaglandin G/H synthase 2 reviewed Enzyme PTGS2 IC50 '=' 5000 nM
Q9Y6L6 BXGT022334 Solute carrier organic anion transporter family member 1B1 reviewed Transporter SLCO1B1 Inhibition '=' 157 %
Q96EB6 BXGT019646 NAD-dependent protein deacetylase sirtuin-1 reviewed Epigenetic regulator SIRT1 EC1.5 '=' 46 uM
P05067 BXGT006306 Amyloid-beta precursor protein reviewed Enzyme modulator APP Flu intensity '=' 272 -
Q92731 BXGT019366 Estrogen receptor beta reviewed Nuclear receptor ESR2 Activity '=' 0 %
P07550 BXGT006636 Beta-2 adrenergic receptor reviewed G-protein coupled receptor ADRB2 Ki - - -
P23219 BXGT008837 Prostaglandin G/H synthase 1 reviewed Enzyme PTGS1 Ki - - -
O75762 BXGT005151 Transient receptor potential cation channel subfamily A member 1 reviewed Ion channel TRPA1 Inhibition '=' 2 %
Q13153 BXGT013319 Serine/threonine-protein kinase PAK 1 reviewed Kinase PAK1 IC50 '=' 15000 nM
P05067 BXGT006306 Amyloid-beta precursor protein reviewed Enzyme modulator APP Activity '=' 7 %
P05067 BXGT006306 Amyloid-beta precursor protein reviewed Enzyme modulator APP IC50 '=' 15300 nM
P05067 BXGT006306 Amyloid-beta precursor protein reviewed Enzyme modulator APP Inhibition '=' 30 %
P21397 BXGT008644 Amine oxidase [flavin-containing] A reviewed - MAOA IC50 - - -
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 18356 nM
P02766 BXGT005953 Transthyretin reviewed Transporter TTR Kd '=' 470 nM
P05067 BXGT006306 Amyloid-beta precursor protein reviewed Enzyme modulator APP Inhibition '=' 64 %
P05067 BXGT006306 Amyloid-beta precursor protein reviewed Enzyme modulator APP Flu intensity '=' 250 -
P07339 BXGT006604 Cathepsin D reviewed Enzyme CTSD IC50 '=' 138000 nM
P05067 BXGT006306 Amyloid-beta precursor protein reviewed Enzyme modulator APP Ka '=' 1 10'5/M
P05067 BXGT006306 Amyloid-beta precursor protein reviewed Enzyme modulator APP Inhibition '=' 48 %
P27361 BXGT009176 Mitogen-activated protein kinase 3 reviewed Kinase MAPK3 Ki - - -
P15823 BXGT008160 Alpha-1B adrenergic receptor reviewed - Adra1b IC50 - - -
P14416 BXGT008011 D(2) dopamine receptor reviewed G-protein coupled receptor DRD2 Ki - - -
O75762 BXGT005151 Transient receptor potential cation channel subfamily A member 1 reviewed Ion channel TRPA1 IC50 '>' 30000 nM
P05067 BXGT006306 Amyloid-beta precursor protein reviewed Enzyme modulator APP Inhibition '=' 57 %
P05067 BXGT006306 Amyloid-beta precursor protein reviewed Enzyme modulator APP Inhibition '=' 61 %
P05067 BXGT006306 Amyloid-beta precursor protein reviewed Enzyme modulator APP Activity '=' 44 %
P56817 BXGT011200 Beta-secretase 1 reviewed Enzyme BACE1 Inhibition '<' 50 %
P05067 BXGT006306 Amyloid-beta precursor protein reviewed Enzyme modulator APP Activity '=' 90 %
P14679 BXGT008039 Tyrosinase reviewed Enzyme TYR Activity '=' 80 %
P03372 BXGT006059 Estrogen receptor reviewed Nuclear receptor ESR1 FC '=' 0 -
Q6RI86 BXGT016509 Transient receptor potential cation channel subfamily A member 1 reviewed - Trpa1 EC50 - - -
P05067 BXGT006306 Amyloid-beta precursor protein reviewed Enzyme modulator APP Inhibition '=' 51 %
P05067 BXGT006306 Amyloid-beta precursor protein reviewed Enzyme modulator APP IC50 '=' 12430 nM
P05067 BXGT006306 Amyloid-beta precursor protein reviewed Enzyme modulator APP Activity '=' 58 %
P06276 BXGT006430 Cholinesterase reviewed - BCHE IC50 - - -
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 reviewed Enzyme NFE2L2 EC50 '=' 5400 nM
P05067 BXGT006306 Amyloid-beta precursor protein reviewed Enzyme modulator APP Activity '=' 75 %
P02766 BXGT005953 Transthyretin reviewed Transporter TTR Activity_index '=' 0 -
P03372 BXGT006059 Estrogen receptor reviewed Nuclear receptor ESR1 Activity '=' 0 %
P05067 BXGT006306 Amyloid-beta precursor protein reviewed Enzyme modulator APP Inhibition '=' 65 %
P05067 BXGT006306 Amyloid-beta precursor protein reviewed Enzyme modulator APP Activity '=' 61 %
P22303 BXGT008751 Acetylcholinesterase reviewed Enzyme ACHE Activity - - -
P05067 BXGT006306 Amyloid-beta precursor protein reviewed Enzyme modulator APP Inhibition '=' 78 %
P05067 BXGT006306 Amyloid-beta precursor protein reviewed Enzyme modulator APP Flu intensity '=' 229 -
P05067 BXGT006306 Amyloid-beta precursor protein reviewed Enzyme modulator APP Activity '=' 78 %
P11344 BXGT007687 Tyrosinase reviewed - Tyr Activity '=' 80 %
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF00006 Garden onion Allium cepa Vegetables
BXGF00016 Peanut Arachis hypogaea Nuts
BXGF00036 Turnip Brassica rapa var. rapa Herbs and Spices
BXGF00065 Cucumber Cucumis sativus Gourds
BXGF00083 Strawberry Fragaria X ananassa Fruits
BXGF00087 Sea-buckthornberry Hippophae rhamnoides Fruits
BXGF00116 Mulberry Morus Fruits
BXGF00129 Parsnip Pastinaca sativa Vegetables
BXGF00135 Date Phoenix dactylifera Fruits
BXGF00138 Pine nut Pinus Nuts
BXGF00140 Pistachio Pistacia vera Nuts
BXGF00156 Redcurrant Ribes rubrum Fruits
BXGF00171 Garden tomato Solanum lycopersicum Vegetables
BXGF00191 Highbush blueberry Vaccinium corymbosum Fruits
BXGF00192 American cranberry Vaccinium macrocarpon Fruits
BXGF00193 Bilberry Vaccinium myrtillus Fruits
BXGF00194 Lingonberry Vaccinium vitis-idaea Fruits
BXGF00198 Adzuki bean Vigna angularis Pulses
BXGF00201 Climbing bean Vigna umbellata Pulses
BXGF00204 Common grape Vitis vinifera Fruits
BXGF00213 European cranberry Vaccinium oxycoccos Fruits
BXGF00230 Carrot Daucus carota ssp. sativus Vegetables
BXGF00570 Grape wine Beverages
BXGF00571 Berry wine Beverages
BXGF00585 Vinegar Baking goods
BXGF00642 Chocolate Cocoa and cocoa products
BXGF00806 Alcoholic beverages Beverages
BXGF00821 Nuts Nuts
BXGF00823 Fruits Fruits
BXGF00829 Green bell pepper Capsicum annuum Vegetables
BXGF00830 Yellow bell pepper Capsicum annuum Vegetables
BXGF00833 Italian sweet red pepper Capsicum annuum Vegetables
BXGF00834 Yellow wax bean Phaseolus vulgaris Pulses
BXGF00838 Japanese pumpkin Cucurbita maxima Gourds
BXGF00840 Romaine lettuce Lactuca sativa L. var. longifolia Vegetables
BXGF00931 Ipomoea digitata Ipomoea digitata Medicinal Plant
BXGF00947 Artocarpus dadah Artocarpus dadah Medicinal Plant
BXGF00981 Flacourtia jangomas Flacourtia jangomas Medicinal Plant
BXGF01022 Heliotropium hirsutum Heliotropium hirsutum Medicinal Plant
BXGF01034 Annona cornifolia Annona cornifolia Human Edible Plant
BXGF01088 Maytenus imbricata Maytenus imbricata Others
BXGF01126 Polygonum cuspidatum Polygonum cuspidatum Medicinal Plant
BXGF01174 Salvia syriaca Salvia syriaca Others
BXGF01176 Curcuma xanthorrhiza Curcuma xanthorrhiza Medicinal Plant
BXGF01187 Onobrychis arenaria Onobrychis arenaria Others
BXGF01204 Solanum laxum Solanum laxum Medicinal Plant
BXGF01223 Eria mollis Eria mollis Others
BXGF01228 Ageratina adenophora Ageratina adenophora Medicinal Plant
BXGF01241 Eleutherococcus sessiliflorus Eleutherococcus sessiliflorus Medicinal Plant
BXGF01302 Dysoxylum cumingianum Dysoxylum cumingianum Others
BXGF01344 Psychotria stachyoides Psychotria stachyoides Others
BXGF01391 Dodonaea viscosa Dodonaea viscosa Medicinal Plant
BXGF01456 Eucalyptus melliodora Eucalyptus melliodora Others
BXGF01460 Dracaena cochinchinensis Dracaena cochinchinensis Medicinal Plant
BXGF01555 Scutellaria amoena Scutellaria amoena Medicinal Plant
BXGF01568 Teucrium yemense Teucrium yemense Others
BXGF01595 Senecio toluccanus Senecio toluccanus Human Edible Plant
BXGF01614 Goniothalamus malayanus Goniothalamus malayanus Others
BXGF01641 Neobalanocarpus heimii Neobalanocarpus heimii Others
BXGF01683 Aconitum tasiromontanum Aconitum tasiromontanum Others
BXGF01721 Humulus lupulus Humulus lupulus Medicinal Plant
BXGF01764 Dendriopoterium menendezii Dendriopoterium menendezii Others
BXGF01794 Adansonia grandidieri Adansonia grandidieri Human Edible Plant
BXGF01812 Physalis alkekengi Physalis alkekengi Medicinal Plant
BXGF01834 Lysimachia mauritiana Lysimachia mauritiana Others
BXGF01836 Aphyllocladus denticulatus Aphyllocladus denticulatus Others
BXGF01850 Bassia muricata Bassia muricata Medicinal Plant
BXGF01883 Swertia franchetiana Swertia franchetiana Medicinal Plant
BXGF01947 Senecio subdentatus Senecio subdentatus Others
BXGF01989 Helipterum roseum Helipterum roseum Others
BXGF02006 Aconitum seravschanicum Aconitum seravschanicum Others
BXGF02050 Hedysarum connatum Hedysarum connatum Others
BXGF02085 Sideritis chamaedryfolia Sideritis chamaedryfolia Others
BXGF02088 Zanthoxylum tetraspermum Zanthoxylum tetraspermum Medicinal Plant
BXGF02125 Artemisia assoana Artemisia assoana Others
BXGF02183 Dumortiera hirsuta Dumortiera hirsuta Medicinal Plant
BXGF02246 Lepisorus ussuriensis Lepisorus ussuriensis Medicinal Plant
BXGF02273 Trifolium dubium Trifolium dubium Medicinal Plant
BXGF02295 Alstonia spathulata Alstonia spathulata Others
BXGF02326 Phoebe pittieri Phoebe pittieri Others
BXGF02361 Hypericum laricifolium Hypericum laricifolium Medicinal Plant
BXGF02400 Hylotelephium telephium Hylotelephium telephium Medicinal Plant
BXGF02410 Adiantum lunulatum Adiantum lunulatum Medicinal Plant
BXGF02460 Peltostigma guatemalense Peltostigma guatemalense Others
BXGF02491 Acacia adunca Acacia adunca Others
BXGF02515 Viguiera incana Viguiera incana Others
BXGF02529 Astragalus sempervirens Astragalus sempervirens Others
BXGF02554 Marrubium anisodon Marrubium anisodon Medicinal Plant
BXGF02565 Piper caninum Piper caninum Medicinal Plant
BXGF02593 Wikstroemia retusa Wikstroemia retusa Others
BXGF02606 Naucleopsis ternstroemiiflora Naucleopsis ternstroemiiflora Others
BXGF02634 Andrographis lineata Andrographis lineata Medicinal Plant
BXGF02642 Vigna umbeuata Vigna umbeuata Others
BXGF02662 Rheum wittrocki Rheum wittrocki Medicinal Plant
BXGF02773 Carica pennata Carica pennata Others
BXGF02795 Baccharis patagonica Baccharis patagonica Others
BXGF02823 Cassia dentata Cassia dentata Medicinal Plant
BXGF02831 Hoya australis Hoya australis Others
BXGF03131 Astragalus cibarius Astragalus cibarius Medicinal Plant
BXGF03158 Rheum officinale Rheum officinale Medicinal Plant
BXGF03205 Veratrum dahuricum Veratrum dahuricum Others
BXGF03291 Vernonia menthaefolia Vernonia menthaefolia Others
BXGF03318 Capsicum tetragonum Capsicum tetragonum Others
BXGF03353 Aconitum heterophylloides Aconitum heterophylloides Others
BXGF03485 Justicia secunda Justicia secunda Others
BXGF03739 Gymnosporia diversifolia Gymnosporia diversifolia Others
BXGF03934 Lycoris traubii Lycoris traubii Others
BXGF03947 Rumex maritimus Rumex maritimus Medicinal Plant
BXGF03988 Rheum coreanum Rheum coreanum Others
BXGF04053 Smilax china Smilax china Medicinal Plant
BXGF04065 Vatica rassak Vatica rassak Medicinal Plant
BXGF04205 Aster sedifolius Aster sedifolius Others
BXGF04209 Chaenomeles sinensis Chaenomeles sinensis Medicinal Plant
BXGF04258 Rubia cordifolia Rubia cordifolia Medicinal Plant
BXGF04350 Lygodium flexuosum Lygodium flexuosum Medicinal Plant
BXGF04539 Rheum palmatum Rheum palmatum Medicinal Plant
BXGF04607 Morus alba Morus alba Medicinal Plant
BXGF04691 Oroxylum indicum Oroxylum indicum Medicinal Plant
BXGF04709 Strychnos staudtii Strychnos staudtii Others
BXGF04727 Dictyoloma incanescens Dictyoloma incanescens Others
BXGF04738 Saccharum spontaneum Saccharum spontaneum Medicinal Plant
BXGF04746 Crotalaria anagyroides Crotalaria anagyroides Medicinal Plant
BXGF04758 Caragana sinica Caragana sinica Medicinal Plant
BXGF04778 Dasymaschalon sootepense Dasymaschalon sootepense Others
BXGF04782 Croton poilanei Croton poilanei Others
BXGF04794 Tsuga mertensiana Tsuga mertensiana Medicinal Plant
BXGF04800 Leptactina senegambica Leptactina senegambica Others
BXGF04820 Panax ginseng Panax ginseng 0
BXGF04834 Guatteria melosma Guatteria melosma Others
BXGF04860 Securinega melanthesoides Securinega melanthesoides Others
BXGF04865 Euonymus sachalinensis Euonymus sachalinensis Medicinal Plant
BXGF04870 Felicia erigeroides Felicia erigeroides Others
BXGF04879 Lupinus paniculatus Lupinus paniculatus Others
BXGF04881 Fallopia multiflora Fallopia multiflora Medicinal Plant
BXGF04886 Boehmeria nivea Boehmeria nivea Medicinal Plant
BXGF04986 Ampelopsis brevipedunculata Ampelopsis brevipedunculata Medicinal Plant
BXGF05018 Lavandula vera Lavandula vera Medicinal Plant
BXGF05046 stuhlmannia moavi stuhlmannia moavi Others
BXGF05187 Calostephane divaricata Calostephane divaricata Others
BXGF05261 Artemisia chinensis Artemisia chinensis Medicinal Plant
BXGF05362 Veratrum grandiflorum Veratrum grandiflorum Medicinal Plant
BXGF05369 Daemonorops draco Daemonorops draco Medicinal Plant
BXGF05398 Fritillaria persica Fritillaria persica Medicinal Plant
BXGF05439 Thalictrum glaucum Thalictrum glaucum Others
BXGF05448 Dryopteris crassirhizoma Dryopteris crassirhizoma Medicinal Plant
BXGF05476 Broussonetia papyrifera Broussonetia papyrifera Medicinal Plant
BXGF05507 Eupatorium glutinosum Eupatorium glutinosum Others
BXGF05616 Trinia scabra Trinia scabra Others
BXGF05666 Polyalthia evecta Polyalthia evecta Human Edible Plant
BXGF05742 Caragana aurantiaca Caragana aurantiaca Others
BXGF05787 Smilax glabra Smilax glabra Medicinal Plant
BXGF05857 Iris domestica Iris domestica Medicinal Plant
BXGF05862 Premna odorata Premna odorata Medicinal Plant
BXGF05877 Rheum tanguticum Rheum tanguticum Medicinal Plant
BXGF05899 Coprosma lucida Coprosma lucida Medicinal Plant
BXGF06007 Canthium berberidifolium Canthium berberidifolium Medicinal Plant
BXGF06011 Enceliopsis argophylla Enceliopsis argophylla Others
BXGF06037 Cotyledon secunda Cotyledon secunda Others
BXGF06095 Rheum undulatum Rheum undulatum Medicinal Plant
BXGF06140 Tanacetum parthenium Tanacetum parthenium Medicinal Plant
BXGF06165 Phalaenopsis cornu-cervi Phalaenopsis cornu-cervi Others
BXGF06219 Cotula filicula Cotula filicula Others
BXGF06227 Rauvolfia vomitoria Rauvolfia vomitoria Medicinal Plant
BXGF06237 Gnetum latifolium Gnetum latifolium Medicinal Plant
BXGF06281 Miliusa velutina Miliusa velutina Medicinal Plant
BXGF06289 Leucosceptrum canum Leucosceptrum canum Medicinal Plant
BXGF06290 Cinnamosma macrocarpa Cinnamosma macrocarpa Others
BXGF06328 Garcinia quaesita Garcinia quaesita Human Edible Plant
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease