acompound

Showing entry for Aromadendrin

General Compound Information
BXGC Id	BXGC0002079
Compound Name	Aromadendrin
Structure
Formula	C15H12O6
InchiKey	PADQINQHPQKXNL-LSDHHAIUSA-N
SMILES	O[C@@H]1[C@H](OC2=CC(O)=CC(O)=C2C1=O)C1=CC=C(O)C=C1
Inchi	InChI=1S/C15H12O6/c16-8-3-1-7(2-4-8)15-14(20)13(19)12-10(18)5-9(17)6-11(12)21-15/h1-6,14-18,20H/t14-,15+/m0/s1
IUPAC	(2R,3R)-3,5,7-trihydroxy-2-(4-hydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-4-one
Molecular Weight	288.25
Pubchem Id	122850
Chembl Id	CHEMBL9323

Targets of Information Source

DrugBank

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type

PDB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1

Binding DB

50240348

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
reviewed	BXGT005592	Pancreatic triacylglycerol lipase	reviewed		PNLIP	-	>100000	-	-
reviewed	BXGT011911	Xanthine dehydrogenase/oxidase	reviewed		XDH	-	93800	-	-
reviewed	BXGT004563	Polyphenol oxidase 2	reviewed		PPO2	-	>100000	-	-
reviewed	BXGT009938	Receptor-type tyrosine-protein kinase FLT3	reviewed	Kinase	FLT3	-	>10000	-	-

CHEMBL

CHEMBL9323

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
O42713	BXGT004563	Polyphenol oxidase 2	reviewed	-	PPO2	Inhibition	'='	6	%
O42713	BXGT004563	Polyphenol oxidase 2	reviewed	-	PPO2	Inhibition	'='	6	%
P80457	BXGT011911	Xanthine dehydrogenase/oxidase	reviewed	-	XDH	Inhibition	'='	66	%
P83916	BXGT012025	Chromobox protein homolog 1	reviewed	Epigenetic regulator	CBX1	Potency	-	2511	nM
P11511	BXGT007717	Aromatase	reviewed	Enzyme	CYP19A1	IC50	'>'	40	ug.mL-1
O75496	BXGT005132	Geminin	reviewed	-	GMNN	Potency	-	819	nM
O42713	BXGT004563	Polyphenol oxidase 2	reviewed	-	PPO2	Inhibition	'='	4	%
O42713	BXGT004563	Polyphenol oxidase 2	reviewed	-	PPO2	Inhibition	'='	21	%
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Inhibition	-	-	-
P80457	BXGT011911	Xanthine dehydrogenase/oxidase	reviewed	-	XDH	IC50	'='	93800	nM
P00591	BXGT005592	Pancreatic triacylglycerol lipase	reviewed	-	PNLIP	IC50	'>'	100000	nM
P36888	BXGT009938	Receptor-type tyrosine-protein kinase FLT3	reviewed	Kinase	FLT3	IC50	'>'	10000	nM
O42713	BXGT004563	Polyphenol oxidase 2	reviewed	-	PPO2	Inhibition	'='	7	%
O42713	BXGT004563	Polyphenol oxidase 2	reviewed	-	PPO2	IC50	'>'	100000	nM
P05067	BXGT006306	Amyloid-beta precursor protein	reviewed	Enzyme modulator	APP	IC50	'>'	500000	nM
P00591	BXGT005592	Pancreatic triacylglycerol lipase	reviewed	-	PNLIP	Inhibition	'='	10	%

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF00038	Tea	Camellia sinensis	Teas
BXGF00055	Pummelo	Citrus maxima	Fruits
BXGF00124	Common oregano	Origanum vulgare	Herbs and Spices
BXGF00145	Sweet cherry	Prunus avium	Fruits
BXGF00146	Sour cherry	Prunus cerasus	Fruits
BXGF00199	Gram bean	Vigna mungo	Pulses
BXGF00503	Rowal	Pangium edule	Herbs and Spices
BXGF00811	Citrus		Fruits
BXGF00847	Albizia gummifera	Albizia gummifera	Vegetables
BXGF00957	Allagopappus viscosissimus	Allagopappus viscosissimus	Others
BXGF01051	Callicarpa japonica	Callicarpa japonica	Medicinal Plant
BXGF01061	Avrainvillea longicaulis	Avrainvillea longicaulis	Others
BXGF01068	Inulanthera calva	Inulanthera calva	Others
BXGF01173	Astragalus spinosus	Astragalus spinosus	Others
BXGF01235	Swertia decussata	Swertia decussata	Medicinal Plant
BXGF01269	Peltogyne pubescens	Peltogyne pubescens	Others
BXGF01318	Nicotiana raimondii	Nicotiana raimondii	Others
BXGF01321	Ranunculus peltatus	Ranunculus peltatus	Others
BXGF01349	Hydrangea serrata	Hydrangea serrata	Medicinal Plant
BXGF01376	Acicarpha tribuloides	Acicarpha tribuloides	Others
BXGF01437	Lunularia cruciata	Lunularia cruciata	Others
BXGF01546	Vallaris heynei	Vallaris heynei	Medicinal Plant
BXGF01597	Senegalia catechu	Senegalia catechu	Medicinal Plant
BXGF01599	Helichrysum cephaloideum	Helichrysum cephaloideum	Medicinal Plant
BXGF01684	Hemionitis japonica	Hemionitis japonica	Others
BXGF01793	Sedum obtuso-lineare	Sedum obtuso-lineare	Others
BXGF01890	Trollius chinensis	Trollius chinensis	Medicinal Plant
BXGF02027	Achillea lycaonica	Achillea lycaonica	Others
BXGF02053	Hypericum balearicum	Hypericum balearicum	Others
BXGF02064	Corymbia citriodora	Corymbia citriodora	Medicinal Plant
BXGF02139	Scolopia chinensis	Scolopia chinensis	Others
BXGF02171	Centaurea musimomum	Centaurea musimomum	Others
BXGF02199	Bryum argenteum	Bryum argenteum	Medicinal Plant
BXGF02341	Euphorbia amygdaloides	Euphorbia amygdaloides	Medicinal Plant
BXGF02380	Entada phaseoloides	Entada phaseoloides	Medicinal Plant
BXGF02421	Hesperis matronalis	Hesperis matronalis	Medicinal Plant
BXGF02449	Jatropha macrorhiza	Jatropha macrorhiza	Others
BXGF02523	Andira inermis	Andira inermis	Medicinal Plant
BXGF02540	Jackiella javanica	Jackiella javanica	Medicinal Plant
BXGF02587	Rhus vulgaris	Rhus vulgaris	Human Edible Plant
BXGF02610	Cladrastis platycarpa	Cladrastis platycarpa	Others
BXGF02646	Eremanthus seidelii	Eremanthus seidelii	Others
BXGF02687	Papaver tatricum	Papaver tatricum	Others
BXGF02732	Senecio adenophyllus	Senecio adenophyllus	Others
BXGF02768	Lilium umbellatum	Lilium umbellatum	Others
BXGF02784	Artemisia rehan	Artemisia rehan	Others
BXGF02796	Centaurea arbutifolia	Centaurea arbutifolia	Others
BXGF02807	Elephantopus hirtiflorus	Elephantopus hirtiflorus	Others
BXGF02828	Nematolepis phebalioides	Nematolepis phebalioides	Others
BXGF02839	Solidago flexicaulis	Solidago flexicaulis	Human Edible Plant
BXGF02854	Ligularia cymbulifera	Ligularia cymbulifera	Others
BXGF02877	Coprosma areolata	Coprosma areolata	Medicinal Plant
BXGF02901	Senecio zoellneri	Senecio zoellneri	Others
BXGF02907	Oreopteris quelpaertensis	Oreopteris quelpaertensis	Others
BXGF02948	Viguiera linearis	Viguiera linearis	Others
BXGF03094	Menispermum dauricum	Menispermum dauricum	Medicinal Plant
BXGF03110	Gleditsia sinensis	Gleditsia sinensis	Medicinal Plant
BXGF03118	Piper acutifolium	Piper acutifolium	Medicinal Plant
BXGF03247	Anastatica hierochuntica	Anastatica hierochuntica	Medicinal Plant
BXGF03308	Bidens tripartita	Bidens tripartita	Medicinal Plant
BXGF03313	Magnolia montana	Magnolia montana	Medicinal Plant
BXGF03363	Hypericum japonicum	Hypericum japonicum	Medicinal Plant
BXGF03405	Genista sessilifolia	Genista sessilifolia	Others
BXGF03467	Corydalis sewerzowi	Corydalis sewerzowi	Medicinal Plant
BXGF03493	Trapa bicornis	Trapa bicornis	Medicinal Plant
BXGF03504	Sterculia foetida	Sterculia foetida	Medicinal Plant
BXGF03594	Cacalia robusta	Cacalia robusta	Others
BXGF03609	Xyris indica	Xyris indica	Medicinal Plant
BXGF03629	Aconitum palmatum	Aconitum palmatum	Medicinal Plant
BXGF03650	Onoseris alata	Onoseris alata	Others
BXGF03659	Carpesium faberi	Carpesium faberi	Others
BXGF03668	Vellozia streptophylla	Vellozia streptophylla	Others
BXGF03681	Aconitum tianschanicum	Aconitum tianschanicum	Others
BXGF03691	Solanum diflorum	Solanum diflorum	Others
BXGF03699	Staehelina fruticosa	Staehelina fruticosa	Others
BXGF03708	Gomphostemma parviflorum	Gomphostemma parviflorum	Others
BXGF03717	Chlamydomonas allensworthii	Chlamydomonas allensworthii	Others
BXGF03727	Hippobroma longiflora	Hippobroma longiflora	Others
BXGF03731	Rosulabryum capillare	Rosulabryum capillare	Others
BXGF03733	Alpinia officinarum	Alpinia officinarum	Medicinal Plant
BXGF03736	Psilotum nudum	Psilotum nudum	Medicinal Plant
BXGF03748	Ventilago leiocarpa	Ventilago leiocarpa	Medicinal Plant
BXGF03754	Sapindus emarginatus	Sapindus emarginatus	Medicinal Plant
BXGF03774	Citrus rugulosa	Citrus rugulosa	Others
BXGF03784	Codonopsis cordifolioidea	Codonopsis cordifolioidea	Human Edible Plant
BXGF03819	Ariocarpus fissuratus	Ariocarpus fissuratus	Human Edible Plant
BXGF03982	Maytenus retusa	Maytenus retusa	Others
BXGF04053	Smilax china	Smilax china	Medicinal Plant
BXGF04060	Aglaia australiensis	Aglaia australiensis	Others
BXGF04255	Gmelina asiatica	Gmelina asiatica	Medicinal Plant
BXGF04263	Glycine soja	Glycine soja	Medicinal Plant
BXGF04274	Macadamia ternifolia	Macadamia ternifolia	Medicinal Plant
BXGF04284	Heliotropium hirsutissimum	Heliotropium hirsutissimum	Others
BXGF04301	Dorstenia dinklagei	Dorstenia dinklagei	Others
BXGF04328	Croton zehntneri	Croton zehntneri	Others
BXGF04389	Humulus japonicus	Humulus japonicus	Medicinal Plant
BXGF04659	Phyllanthus emblica	Phyllanthus emblica	Medicinal Plant
BXGF04772	Sapium haematospermum	Sapium haematospermum	Medicinal Plant
BXGF04817	Euonymus alatus	Euonymus alatus	Medicinal Plant
BXGF04837	Nekemias grossedentata	Nekemias grossedentata	Others
BXGF04967	Cudrania tricuspidata	Cudrania tricuspidata	Medicinal Plant
BXGF04986	Ampelopsis brevipedunculata	Ampelopsis brevipedunculata	Medicinal Plant
BXGF05041	Desmodium styracifolium	Desmodium styracifolium	Medicinal Plant
BXGF05050	Diplacus longiflorus	Diplacus longiflorus	Others
BXGF05128	Pittocaulon velatum	Pittocaulon velatum	Others
BXGF05129	Achillea pseudopectinata	Achillea pseudopectinata	Others
BXGF05202	Flemingia philippinensis	Flemingia philippinensis	Medicinal Plant
BXGF05212	Trollius europaeus	Trollius europaeus	Medicinal Plant
BXGF05285	Aglaia formosana	Aglaia formosana	Others
BXGF05328	Syzygium nervosum	Syzygium nervosum	Human Edible Plant
BXGF05366	Lepidosperma ustulatum	Lepidosperma ustulatum	Others
BXGF05432	Ampelopsis glandulosa var. brevipedunculata	Ampelopsis glandulosa var. brevipedunculata	Others
BXGF05476	Broussonetia papyrifera	Broussonetia papyrifera	Medicinal Plant
BXGF05526	Salvia miltiorrhiza	Salvia miltiorrhiza	Medicinal Plant
BXGF05532	Aniba rosaeodora	Aniba rosaeodora	Medicinal Plant
BXGF05678	Dunalia solanacea	Dunalia solanacea	Others
BXGF05761	Berberis floribunda	Berberis floribunda	Medicinal Plant
BXGF05787	Smilax glabra	Smilax glabra	Medicinal Plant
BXGF05820	Jamesoniella colorata	Jamesoniella colorata	Medicinal Plant
BXGF05833	Dahlstedtia pentaphylla	Dahlstedtia pentaphylla	Others
BXGF05875	Fumaria micrantha	Fumaria micrantha	Others
BXGF05876	Gleditsia japonica	Gleditsia japonica	Medicinal Plant
BXGF05935	Pterodon emarginatus	Pterodon emarginatus	Others
BXGF05948	Berlinia tomentosa	Berlinia tomentosa	Others
BXGF06014	Cymodocea nodosa	Cymodocea nodosa	Others
BXGF06077	Bonamia spectabilis	Bonamia spectabilis	Others
BXGF06129	Atuna racemosa	Atuna racemosa	Human Edible Plant
BXGF06180	Astragalus pycnanthus	Astragalus pycnanthus	Others
BXGF06223	Pulsatilla campanella	Pulsatilla campanella	Medicinal Plant
BXGF06294	Arum maximum	Arum maximum	Others

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}