acompound

Showing entry for Lormetazepam

　　　　　　　　　　　　　　　

General Compound Information
BXGC Id	BXGC0003885
Compound Name	Lormetazepam
Structure
Formula	C16H12Cl2N2O2
InchiKey	FJIKWRGCXUCUIG-UHFFFAOYSA-N
SMILES	CN1C2=C(C=C(Cl)C=C2)C(=NC(O)C1=O)C1=CC=CC=C1Cl
Inchi	InChI=1S/C16H12Cl2N2O2/c1-20-13-7-6-9(17)8-11(13)14(19-15(21)16(20)22)10-4-2-3-5-12(10)18/h2-8,15,21H,1H3
IUPAC	7-chloro-5-(2-chlorophenyl)-3-hydroxy-1-methyl-2,3-dihydro-1H-1,4-benzodiazepin-2-one
Molecular Weight	335.19
Pubchem Id	13314
Chembl Id	CHEMBL22097

Targets of Information Source

DrugBank

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
P14867	BXGT008061	Gamma-aminobutyric acid receptor subunit alpha-1	reviewed	Ion channel	GABRA1	approved	-
P47869	BXGT010590	Gamma-aminobutyric acid receptor subunit alpha-2	reviewed	Ion channel	GABRA2	approved	-
P34903	BXGT009769	Gamma-aminobutyric acid receptor subunit alpha-3	reviewed	Ion channel	GABRA3	approved	-
P48169	BXGT010622	Gamma-aminobutyric acid receptor subunit alpha-4	reviewed	Ion channel	GABRA4	approved	-
P31644	BXGT009557	Gamma-aminobutyric acid receptor subunit alpha-5	reviewed	Ion channel	GABRA5	approved	-
Q16445	BXGT013629	Gamma-aminobutyric acid receptor subunit alpha-6	reviewed	Ion channel	GABRA6	approved	-
P18505	BXGT008409	Gamma-aminobutyric acid receptor subunit beta-1	reviewed	Ion channel	GABRB1	approved	-
P47870	BXGT010591	Gamma-aminobutyric acid receptor subunit beta-2	reviewed	Ion channel	GABRB2	approved	-
P28472	BXGT009260	Gamma-aminobutyric acid receptor subunit beta-3	reviewed	Ion channel	GABRB3	approved	-
O14764	BXGT004094	Gamma-aminobutyric acid receptor subunit delta	reviewed	Ion channel	GABRD	approved	-
P78334	BXGT011834	Gamma-aminobutyric acid receptor subunit epsilon	reviewed	Ion channel	GABRE	approved	-
Q8N1C3	BXGT018498	Gamma-aminobutyric acid receptor subunit gamma-1	reviewed	Ion channel	GABRG1	approved	-
P18507	BXGT008411	Gamma-aminobutyric acid receptor subunit gamma-2	reviewed	Ion channel	GABRG2	approved	-
Q99928	BXGT019975	Gamma-aminobutyric acid receptor subunit gamma-3	reviewed	Ion channel	GABRG3	approved	ligand
O00591	BXGT003939	Gamma-aminobutyric acid receptor subunit pi	reviewed	Ion channel	GABRP	approved	-
Q9UN88	BXGT021783	Gamma-aminobutyric acid receptor subunit theta	reviewed	Ion channel	GABRQ	approved	positive allosteric modulator

PDB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1

Binding DB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM

CHEMBL

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF00175	Potato	Solanum tuberosum	Vegetables

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}