Showing entry for 3-Hydroxyanthranilic acid


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0004762
Compound Name3-Hydroxyanthranilic acid
Structure
FormulaC7H7NO3
InchiKeyWJXSWCUQABXPFS-UHFFFAOYSA-N
SMILESNC1=C(O)C=CC=C1C(O)=O
InchiInChI=1S/C7H7NO3/c8-6-4(7(10)11)2-1-3-5(6)9/h1-3,9H,8H2,(H,10,11)
IUPAC2-amino-3-hydroxybenzoic acid
Molecular Weight153.14
Pubchem Id86
Chembl IdCHEMBL445304
Targets of Information Source
DrugBank DB03644
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Q51792 BXGT014966 Trans-2,3-dihydro-3-hydroxyanthranilate isomerase reviewed - phzF experimental -
PDB 3HA
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Q51792 BXGT014966 Trans-2,3-dihydro-3-hydroxyanthranilate isomerase reviewed phzF - - - 1400 -
Q1LCS4 BXGT013813 3-hydroxyanthranilate 3,4-dioxygenase reviewed nbaC - - - - -
A0A022MRT4 BXGT025565 AMP-dependent synthetase and ligase unreviewed natL2 - - - - -
A0A022MQ12 BXGT025566 Amidohydrolase unreviewed natAM - - - - -
Binding DB n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
CHEMBL CHEMBL445304
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
Q15118 BXGT013540 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial reviewed Kinase PDK1 Activity - - -
P03070 BXGT006016 Large T antigen reviewed - IC50 - 20090 nM
O94925 BXGT005342 Glutaminase kidney isoform, mitochondrial reviewed Enzyme GLS Potency - 35481 nM
Q9BHT9 BXGT020096 Glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase unreviewed - G6PD-6PGL IC50 '>' 80000 nM
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 reviewed Enzyme NFE2L2 Potency - 20596 nM
P9WMR3 BXGT012397 Replicative DNA helicase reviewed - dnaB AC50 '=' 27170 nM
Q9UNA4 BXGT021785 DNA polymerase iota reviewed - POLI Potency - 39810 nM
P11413 BXGT007701 Glucose-6-phosphate 1-dehydrogenase reviewed Enzyme G6PD IC50 '=' 24000 nM
O75874 BXGT005157 Isocitrate dehydrogenase [NADP] cytoplasmic reviewed - IDH1 Potency - 50118 nM
O89049 BXGT005293 Thioredoxin reductase 1, cytoplasmic reviewed - Txnrd1 Potency - 79432 nM
Q9BHT9 BXGT020096 Glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase unreviewed - G6PD-6PGL IC50 '=' 1440 nM
O75164 BXGT005104 Lysine-specific demethylase 4A reviewed - KDM4A Potency - 56234 nM
Q9UBT6 BXGT021664 DNA polymerase kappa reviewed - POLK Potency - 56234 nM
P55212 BXGT011112 Caspase-6 reviewed Enzyme CASP6 AC50 '=' 1590 nM
P10747 BXGT007609 T-cell-specific surface glycoprotein CD28 reviewed - CD28 Activity - - -
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 29092 nM
P9WHJ3 BXGT012297 Protein RecA reviewed - recA EC50 '=' 5430 nM
P55210 BXGT011110 Caspase-7 reviewed Enzyme CASP7 AC50 '=' 6140 nM
Q9BHT9 BXGT020096 Glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase unreviewed - G6PD-6PGL IC50 '=' 40900 nM
P55211 BXGT011111 Caspase-9 reviewed Enzyme CASP9 AC50 '>' 70000 nM
P9WMR3 BXGT012397 Replicative DNA helicase reviewed - dnaB AC50 '>' 380000 nM
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF00809 Brassicas Vegetables
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease