acompound

Showing entry for Cyclocurcumin

　　　　　　　　　　　　　　　

General Compound Information
BXGC Id	BXGC0005139
Compound Name	Cyclocurcumin
Structure
Formula	C21H20O6
InchiKey	IZLBLUIBVMGMIY-ZZXKWVIFSA-N
SMILES	COC1=C(O)C=CC(\C=C\C2=CC(=O)CC(O2)C2=CC(OC)=C(O)C=C2)=C1
Inchi	InChI=1S/C21H20O6/c1-25-20-9-13(4-7-17(20)23)3-6-16-11-15(22)12-19(27-16)14-5-8-18(24)21(10-14)26-2/h3-11,19,23-24H,12H2,1-2H3/b6-3+
IUPAC	2-(4-hydroxy-3-methoxyphenyl)-6-[(E)-2-(4-hydroxy-3-methoxyphenyl)ethenyl]-3,4-dihydro-2H-pyran-4-one
Molecular Weight	368.38
Pubchem Id	69879809
Chembl Id	CHEMBL4098368

Targets of Information Source

DrugBank

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type

PDB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1

Binding DB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM

CHEMBL

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
P27732	BXGT009204	Voltage-dependent L-type calcium channel subunit alpha-1D	reviewed	-	Cacna1d	Inhibition	-	-	-
Q02485	BXGT012654	Voltage-dependent L-type calcium channel subunit alpha-1S	reviewed	-	Cacna1s	Inhibition	-	-	-
P22002	BXGT008717	Voltage-dependent L-type calcium channel subunit alpha-1C	reviewed	-	Cacna1c	Inhibition	-	-	-
P27732	BXGT009204	Voltage-dependent L-type calcium channel subunit alpha-1D	reviewed	-	Cacna1d	IC50	'='	13500	nM
Q02485	BXGT012654	Voltage-dependent L-type calcium channel subunit alpha-1S	reviewed	-	Cacna1s	IC50	'='	13500	nM
P22002	BXGT008717	Voltage-dependent L-type calcium channel subunit alpha-1C	reviewed	-	Cacna1c	IC50	'='	13500	nM
P27732	BXGT009204	Voltage-dependent L-type calcium channel subunit alpha-1D	reviewed	-	Cacna1d	IC50	'='	18500	nM
Q02485	BXGT012654	Voltage-dependent L-type calcium channel subunit alpha-1S	reviewed	-	Cacna1s	IC50	'='	18500	nM
P22002	BXGT008717	Voltage-dependent L-type calcium channel subunit alpha-1C	reviewed	-	Cacna1c	IC50	'='	18500	nM
P27732	BXGT009204	Voltage-dependent L-type calcium channel subunit alpha-1D	reviewed	-	Cacna1d	Kd	'='	6309	nM
Q02485	BXGT012654	Voltage-dependent L-type calcium channel subunit alpha-1S	reviewed	-	Cacna1s	Kd	'='	6309	nM
P22002	BXGT008717	Voltage-dependent L-type calcium channel subunit alpha-1C	reviewed	-	Cacna1c	Kd	'='	6309	nM
P27732	BXGT009204	Voltage-dependent L-type calcium channel subunit alpha-1D	reviewed	-	Cacna1d	IC50	'='	14900	nM
Q02485	BXGT012654	Voltage-dependent L-type calcium channel subunit alpha-1S	reviewed	-	Cacna1s	IC50	'='	14900	nM
P22002	BXGT008717	Voltage-dependent L-type calcium channel subunit alpha-1C	reviewed	-	Cacna1c	IC50	'='	14900	nM

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF00068	Turmeric	Curcuma longa	Herbs and Spices
BXGF00818	Herbs and Spices		Herbs and Spices

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}