Showing entry for (+)-Syringaresinol


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0007668
Compound Name(+)-Syringaresinol
Structure
FormulaC22H26O8
InchiKeyKOWMJRJXZMEZLD-HCIHMXRSSA-N
SMILES[H][C@]12CO[C@H](C3=CC(OC)=C(O)C(OC)=C3)[C@@]1([H])CO[C@@H]2C1=CC(OC)=C(O)C(OC)=C1
InchiInChI=1S/C22H26O8/c1-25-15-5-11(6-16(26-2)19(15)23)21-13-9-30-22(14(13)10-29-21)12-7-17(27-3)20(24)18(8-12)28-4/h5-8,13-14,21-24H,9-10H2,1-4H3/t13-,14-,21+,22+/m0/s1
IUPAC4-[(1S,3aR,4S,6aR)-4-(4-hydroxy-3,5-dimethoxyphenyl)-hexahydrofuro[3,4-c]furan-1-yl]-2,6-dimethoxyphenol
Molecular Weight418.44
Pubchem Id443023
Chembl IdCHEMBL361362
Targets of Information Source
DrugBank n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
PDB n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Binding DB 50349826
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
reviewed BXGT004599 Forkhead box protein O3 reviewed FOXO3 - - 1730000 -
reviewed BXGT012701 Peroxisome proliferator-activated receptor delta reviewed Nuclear receptor PPARD - - - 18110
reviewed BXGT012701 Peroxisome proliferator-activated receptor delta reviewed Nuclear receptor PPARD - - 27620 -
reviewed BXGT004563 Polyphenol oxidase 2 reviewed PPO2 - >1000000 - -
reviewed BXGT008369 Tyrosine-protein phosphatase non-receptor type 1 reviewed PTPN1 - 15010 - -
CHEMBL CHEMBL361362
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
P35396 BXGT009824 Peroxisome proliferator-activated receptor delta reviewed - Ppard FC '=' 4 -
Q03181 BXGT012701 Peroxisome proliferator-activated receptor delta reviewed Nuclear receptor PPARD Activity - - -
P35396 BXGT009824 Peroxisome proliferator-activated receptor delta reviewed - Ppard FC '=' 1 -
O96394 BXGT005423 Arginase unreviewed - IC50 '=' 13700 nM
P18031 BXGT008369 Tyrosine-protein phosphatase non-receptor type 1 reviewed - PTPN1 IC50 '=' 15010 nM
P35396 BXGT009824 Peroxisome proliferator-activated receptor delta reviewed - Ppard Activity - - -
P11387 BXGT007696 DNA topoisomerase 1 reviewed Enzyme TOP1 Effect '=' 15 %
Q03181 BXGT012701 Peroxisome proliferator-activated receptor delta reviewed Nuclear receptor PPARD EC50 '=' 18110 nM
O43524 BXGT004599 Forkhead box protein O3 reviewed - FOXO3 Kd '=' 1730000 nM
P35396 BXGT009824 Peroxisome proliferator-activated receptor delta reviewed - Ppard FC '=' 3 -
P11387 BXGT007696 DNA topoisomerase 1 reviewed Enzyme TOP1 Effect '=' 2 %
P11387 BXGT007696 DNA topoisomerase 1 reviewed Enzyme TOP1 Effect '=' 8 %
O42713 BXGT004563 Polyphenol oxidase 2 reviewed - PPO2 IC50 '>' 1000000 nM
P35396 BXGT009824 Peroxisome proliferator-activated receptor delta reviewed - Ppard FC '=' 2 -
Q03181 BXGT012701 Peroxisome proliferator-activated receptor delta reviewed Nuclear receptor PPARD Kd '=' 27620 nM
O43524 BXGT004599 Forkhead box protein O3 reviewed - FOXO3 Activity - - -
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF00004 Kiwi Actinidia chinensis Fruits
BXGF00012 Pineapple Ananas comosus Fruits
BXGF00021 Asparagus Asparagus officinalis Vegetables
BXGF00022 Oat Avena sativa Cereals and cereal products
BXGF00079 Common buckwheat Fagopyrum esculentum Cereals and cereal products
BXGF00088 Barley Hordeum vulgare Cereals and cereal products
BXGF00105 Apple Malus pumila Fruits
BXGF00114 Medlar Mespilus germanica Fruits
BXGF00151 Pomegranate Punica granatum Fruits
BXGF00169 Rye Secale cereale Cereals and cereal products
BXGF00170 Sesame Sesamum orientale Herbs and Spices
BXGF00173 Garden tomato (var.) Solanum lycopersicum var. lycopersicum Vegetables
BXGF00174 Eggplant Solanum melongena Vegetables
BXGF00187 Common wheat Triticum aestivum Cereals and cereal products
BXGF00245 Radish (var.) Raphanus sativus var. sativus Vegetables
BXGF00301 Cherimoya Annona cherimola Fruits
BXGF00337 Ginkgo nuts Ginkgo biloba Herbs and Spices
BXGF00557 Black salsify Scorzonera hispanica Vegetables
BXGF00570 Grape wine Beverages
BXGF00651 Tofu Soy
BXGF00912 Plectranthus nummularius Plectranthus nummularius Medicinal Plant
BXGF00979 Cistanche deserticola Cistanche deserticola Medicinal Plant
BXGF01028 Machilus odoratissima Machilus odoratissima Medicinal Plant
BXGF01031 Epimedium sagittatum Epimedium sagittatum Medicinal Plant
BXGF01060 Baccharis grandicapitulata Baccharis grandicapitulata Others
BXGF01064 Lepidium apetalum Lepidium apetalum Medicinal Plant
BXGF01071 Sideritis perfoliata Sideritis perfoliata Human Edible Plant
BXGF01077 Entada polystachya Entada polystachya Others
BXGF01079 Renealmia alpinia Renealmia alpinia Human Edible Plant
BXGF01083 Elymus repens Elymus repens Medicinal Plant
BXGF01098 Gynochthodes parvifolia Gynochthodes parvifolia Medicinal Plant
BXGF01148 Arachniodes mutica Arachniodes mutica Others
BXGF01163 Entada africana Entada africana Medicinal Plant
BXGF01207 Morella pensylvanica Morella pensylvanica Others
BXGF01213 Iberis sempervirens Iberis sempervirens Others
BXGF01237 Magnolia obovata Magnolia obovata Medicinal Plant
BXGF01260 Eleutherococcus senticosus Eleutherococcus senticosus Medicinal Plant
BXGF01267 Dendrobium chrysanthum Dendrobium chrysanthum Medicinal Plant
BXGF01276 Delphinium giraldii Delphinium giraldii Medicinal Plant
BXGF01315 Ipomoea purpurea Ipomoea purpurea Medicinal Plant
BXGF01320 Jasione montana Jasione montana Others
BXGF01324 Albizia julibrissin Albizia julibrissin Medicinal Plant
BXGF01337 Stellaria media Stellaria media Medicinal Plant
BXGF01359 Daphne feddei Daphne feddei Others
BXGF01369 Descurainia sophia Descurainia sophia Medicinal Plant
BXGF01399 Psiadia anchusifolia Psiadia anchusifolia Others
BXGF01476 Stephania tetrandra Stephania tetrandra Medicinal Plant
BXGF01493 Curcuma aeruginosa Curcuma aeruginosa Medicinal Plant
BXGF01495 Pleione yunnanensis Pleione yunnanensis Others
BXGF01528 Corydalis conspersa Corydalis conspersa Others
BXGF01549 Sinomenium acutum Sinomenium acutum Medicinal Plant
BXGF01603 Piper brachystachyum Piper brachystachyum Medicinal Plant
BXGF01607 Arcangelisia gusanlung Arcangelisia gusanlung Human Edible Plant
BXGF01608 Schumanniophyton magnificum Schumanniophyton magnificum Others
BXGF01609 Epimedium sempervirens Epimedium sempervirens Others
BXGF01624 Acacia pachyphloia Acacia pachyphloia Others
BXGF01688 Tephroseris kirilowii Tephroseris kirilowii Medicinal Plant
BXGF01755 Fumaria indica Fumaria indica Medicinal Plant
BXGF01811 Dioscorea gracillima Dioscorea gracillima Medicinal Plant
BXGF01835 Dioscorea nipponica Dioscorea nipponica Medicinal Plant
BXGF01856 Aquilaria sinensis Aquilaria sinensis Medicinal Plant
BXGF01917 Vitex limonifolia Vitex limonifolia Others
BXGF01958 Magnolia denudata Magnolia denudata Medicinal Plant
BXGF01967 Senecio congestus Senecio congestus Medicinal Plant
BXGF01980 Eichhornia crassipes Eichhornia crassipes Medicinal Plant
BXGF02001 Sideritis grandiflora Sideritis grandiflora Others
BXGF02043 Ailanthus altissima Ailanthus altissima Medicinal Plant
BXGF02045 Echium rubrum Echium rubrum Others
BXGF02089 Ligustrum ovalifolium Ligustrum ovalifolium Others
BXGF02111 Mikania luetzelburgii Mikania luetzelburgii Others
BXGF02124 Papaver pseudocanescens Papaver pseudocanescens Others
BXGF02242 Sideritis dasygnaphala Sideritis dasygnaphala Others
BXGF02303 Centipeda cunninghami Centipeda cunninghami Others
BXGF02370 Epimedium pubescens Epimedium pubescens Medicinal Plant
BXGF02382 Gutierrezia dracunculoides Gutierrezia dracunculoides Others
BXGF02388 Ipomoea nil Ipomoea nil Medicinal Plant
BXGF02423 Psidium acutangulum Psidium acutangulum Human Edible Plant
BXGF02440 Beesia calthifolia Beesia calthifolia Others
BXGF02468 Sambucus williamsii Sambucus williamsii Medicinal Plant
BXGF02483 Bursera kerberi Bursera kerberi Others
BXGF02496 Pleione bulbocodioides Pleione bulbocodioides Others
BXGF02499 Cremastra appendiculata Cremastra appendiculata Medicinal Plant
BXGF02514 Helenium integrifolium Helenium integrifolium Others
BXGF02543 Rhododendron mucronulatum Rhododendron mucronulatum Medicinal Plant
BXGF02570 Euonymus fortunei Euonymus fortunei Medicinal Plant
BXGF02613 Phlomis crinita Phlomis crinita Medicinal Plant
BXGF02665 Crotalaria stolzii Crotalaria stolzii Others
BXGF02682 Selinum libanotis Selinum libanotis Others
BXGF02705 Capparis flavicans Capparis flavicans Human Edible Plant
BXGF02718 Melampodium leucanthum Melampodium leucanthum Others
BXGF02734 Clerodendrum trichotomum Clerodendrum trichotomum Medicinal Plant
BXGF02750 Juniperus scopulorum Juniperus scopulorum Medicinal Plant
BXGF02785 Clinacanthus nutans Clinacanthus nutans Medicinal Plant
BXGF02827 Alstonia angustiloba Alstonia angustiloba Others
BXGF02840 Lasianthaea podocephala Lasianthaea podocephala Others
BXGF02855 Eucalyptus albens Eucalyptus albens Others
BXGF02881 Epimedium grandiflorum Epimedium grandiflorum Medicinal Plant
BXGF02908 Pellacalyx axillaris Pellacalyx axillaris Others
BXGF02924 Lavandula dentata Lavandula dentata Medicinal Plant
BXGF02950 Boschniakia rossica Boschniakia rossica Medicinal Plant
BXGF03078 Chrysanthemum x morifolium Chrysanthemum x morifolium Medicinal Plant
BXGF03095 Flueggea microcarpa Flueggea microcarpa Medicinal Plant
BXGF03132 Ancistrocladus korupensis Ancistrocladus korupensis Medicinal Plant
BXGF03161 Dendrobium chrysotoxum Dendrobium chrysotoxum Medicinal Plant
BXGF03245 Pyrus ussuriensis Pyrus ussuriensis Medicinal Plant
BXGF03325 Hyperbaena columbica Hyperbaena columbica Others
BXGF03341 Lycopus lucidus Lycopus lucidus Medicinal Plant
BXGF03346 Dendrobium candidum Dendrobium candidum Others
BXGF03370 Maytenus aquifolium Maytenus aquifolium Others
BXGF03398 Solanum nigrum Solanum nigrum Medicinal Plant
BXGF03411 Valeriana wolgensis Valeriana wolgensis Others
BXGF03432 Chrysanthemum indicum Chrysanthemum indicum Medicinal Plant
BXGF03459 Cyanostegia microphylla Cyanostegia microphylla Others
BXGF03473 Maytenus cuzcoina Maytenus cuzcoina Others
BXGF03484 Ranunculus sceleratus Ranunculus sceleratus Medicinal Plant
BXGF03548 Euphorbia leuconeura Euphorbia leuconeura Others
BXGF03583 Epimedium koreanum Epimedium koreanum Medicinal Plant
BXGF03632 Dendrobium fimbriatum Dendrobium fimbriatum Medicinal Plant
BXGF03652 Cinnamomum kotoense Cinnamomum kotoense Others
BXGF03662 Polygonatum odoratum Polygonatum odoratum Medicinal Plant
BXGF03800 Primula integrifolia Primula integrifolia Others
BXGF03817 Coffea liberica var. dewevrei Coffea liberica var. dewevrei Medicinal Plant
BXGF03908 Hedysarum multijugum maxim Hedysarum multijugum maxim Others
BXGF03941 Mycetia nutans Mycetia nutans Medicinal Plant
BXGF04011 Botrychium ternatum Botrychium ternatum Medicinal Plant
BXGF04109 Saussurea costus Saussurea costus Medicinal Plant
BXGF04222 Viburnum grandifolium Viburnum grandifolium Others
BXGF04453 Idesia polycarpa Idesia polycarpa Medicinal Plant
BXGF04532 Solanum nigrum linn Solanum nigrum linn Others
BXGF04719 Radermachera xylocarpa Radermachera xylocarpa Medicinal Plant
BXGF04802 Hibiscus syriacus Hibiscus syriacus Medicinal Plant
BXGF04817 Euonymus alatus Euonymus alatus Medicinal Plant
BXGF04902 Lupinus cosentinii Lupinus cosentinii Others
BXGF05025 solanum violaceum solanum violaceum Medicinal Plant
BXGF05029 Pittosporum brevicalyx Pittosporum brevicalyx Others
BXGF05072 byrsonima coccolobifolia byrsonima coccolobifolia Human Edible Plant
BXGF05076 Anemone narcissiflora Anemone narcissiflora Medicinal Plant
BXGF05173 Dendrobium nobile Dendrobium nobile Medicinal Plant
BXGF05223 Machilus zuihoensis Machilus zuihoensis Medicinal Plant
BXGF05257 Morinda citrifolia Morinda citrifolia Medicinal Plant
BXGF05264 Magnolia officinalis Magnolia officinalis Medicinal Plant
BXGF05297 Isatis tinctoria Isatis tinctoria Medicinal Plant
BXGF05300 Ungernia victoris Ungernia victoris Others
BXGF05318 Hedysarum gmelini Hedysarum gmelini Others
BXGF05370 Epimedium brevicornu Epimedium brevicornu Others
BXGF05465 Euploca racemosa Euploca racemosa Others
BXGF05575 Zanthoxylum chiloperone Zanthoxylum chiloperone Others
BXGF05596 Glinus oppositifolius Glinus oppositifolius Medicinal Plant
BXGF05599 Solanum euacanthum Solanum euacanthum Others
BXGF05634 Roemeria carica Roemeria carica Others
BXGF05722 Hedysarum polybotrys Hedysarum polybotrys Medicinal Plant
BXGF05729 Jurinea maxima Jurinea maxima Others
BXGF05756 Cistanche tubulosa Cistanche tubulosa Medicinal Plant
BXGF05785 Pilocarpus grandiflorus Pilocarpus grandiflorus Others
BXGF06016 Pteris setuloso-costulata Pteris setuloso-costulata Others
BXGF06039 Gentiana strictiflora Gentiana strictiflora Others
BXGF06069 Dendrobium loddigesii Dendrobium loddigesii Medicinal Plant
BXGF06161 Epimedium wushanense Epimedium wushanense Medicinal Plant
BXGF06170 Asclepias curassavica Asclepias curassavica Medicinal Plant
BXGF06205 Pseuduvaria indochinensis Pseuduvaria indochinensis Others
BXGF06217 Morus mongolica Morus mongolica Medicinal Plant
BXGF06268 Zanthoxylum nitidum Zanthoxylum nitidum Medicinal Plant
BXGF06271 Artemisia pectinata Artemisia pectinata Others
BXGF06282 Daphne genkwa Daphne genkwa Medicinal Plant
BXGF06287 Monomeria barbata Monomeria barbata Others
BXGF06305 Isocoma pluriflora Isocoma pluriflora Others
BXGF06307 Zephyranthes flava Zephyranthes flava Others
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease