acompound

Showing entry for Uric acid

　　　　　　　　　　　　　　　

General Compound Information
BXGC Id	BXGC0008062
Compound Name	Uric acid
Structure
Formula	C5H4N4O3
InchiKey	LEHOTFFKMJEONL-UHFFFAOYSA-N
SMILES	O=C1NC2=C(N1)C(=O)NC(=O)N2
Inchi	InChI=1S/C5H4N4O3/c10-3-1-2(7-4(11)6-1)8-5(12)9-3/h(H4,6,7,8,9,10,11,12)
IUPAC	2,3,6,7,8,9-hexahydro-1H-purine-2,6,8-trione
Molecular Weight	168.11
Pubchem Id	1175
Chembl Id	CHEMBL792

Targets of Information Source

DrugBank

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type

PDB

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
P06737	BXGT006492	Glycogen phosphorylase, liver form	reviewed	PYGL	Enzyme	-	-	550000	-
P22985	BXGT008824	Xanthine dehydrogenase/oxidase	reviewed	Xdh	-	-	-	-	-
D0VWQ1	BXGT002712	Uricase	reviewed	uox	-	-	-	-	-
P80457	BXGT011911	Xanthine dehydrogenase/oxidase	reviewed	XDH	-	-	-	-	-
Q00511	BXGT012529	Uricase	reviewed	uaZ	-	-	-	-	-
A6T923	BXGT001481	FAD-dependent urate hydroxylase	reviewed	hpxO	-	-	-	-	-
Q00511	BXGT012529	Uricase	reviewed	uaZ	-	-	-	-	-

Binding DB

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
reviewed	BXGT022246	Guanine deaminase	reviewed	Enzyme	GDA	4340	-	-	-
reviewed	BXGT018794	Solute carrier family 22 member 8	reviewed	Transporter	SLC22A8	275000	-	-	-

CHEMBL

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
Q4U2R8	BXGT014891	Solute carrier family 22 member 6	reviewed	Transporter	SLC22A6	Activity	-	-	-
O35956	BXGT004543	Solute carrier family 22 member 6	reviewed	-	Slc22a6	Activity	-	-	-
Q8TCC7	BXGT018794	Solute carrier family 22 member 8	reviewed	Transporter	SLC22A8	Ki	'='	275000	nM
Q8TCC7	BXGT018794	Solute carrier family 22 member 8	reviewed	Transporter	SLC22A8	Activity	-	-	-
Q4U2R8	BXGT014891	Solute carrier family 22 member 6	reviewed	Transporter	SLC22A6	Km	'='	947000	nM
Q9Y2T3	BXGT022246	Guanine deaminase	reviewed	Enzyme	GDA	Ki	'='	4340	nM
O88909	BXGT005288	Solute carrier family 22 member 8	reviewed	-	Slc22a8	Activity	'='	19	%

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF00099	Garden cress	Lepidium sativum	Vegetables

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}