acompound

Showing entry for 7-Methylchrysin

General Compound Information
BXGC Id	BXGC0008168
Compound Name	7-Methylchrysin
Structure
Formula	C16H12O4
InchiKey	IRZVHDLBAYNPCT-UHFFFAOYSA-N
SMILES	COC1=CC(O)=C2C(=O)C=C(OC2=C1)C1=CC=CC=C1
Inchi	InChI=1S/C16H12O4/c1-19-11-7-12(17)16-13(18)9-14(20-15(16)8-11)10-5-3-2-4-6-10/h2-9,17H,1H3
IUPAC	5-hydroxy-7-methoxy-2-phenyl-4H-chromen-4-one
Molecular Weight	268.26
Pubchem Id	5281954
Chembl Id	CHEMBL164841

Targets of Information Source

DrugBank

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type

PDB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1

Binding DB

50423793

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
reviewed	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	-	-	6310	-

CHEMBL

CHEMBL164841

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
P30561	BXGT009444	Aryl hydrocarbon receptor	reviewed	-	Ahr	Activity	-	-	-
Q96QE3	BXGT019718	ATPase family AAA domain-containing protein 5	reviewed	-	ATAD5	Potency	-	16353	nM
P08684	BXGT006812	Cytochrome P450 3A4	reviewed	Enzyme	CYP3A4	Potency	'='	10000	nM
P04062	BXGT006140	Lysosomal acid glucosylceramidase	reviewed	-	GBA	Potency	-	28183	nM
Q9NUW8	BXGT021219	Tyrosyl-DNA phosphodiesterase 1	reviewed	Enzyme	TDP1	Potency	-	25929	nM
O75496	BXGT005132	Geminin	reviewed	-	GMNN	Potency	-	4	nM
P30561	BXGT009444	Aryl hydrocarbon receptor	reviewed	-	Ahr	FC	'='	11	-
P16473	BXGT008234	Thyrotropin receptor	reviewed	G-protein coupled receptor	TSHR	Potency	'='	31622	nM
P33261	BXGT009707	Cytochrome P450 2C19	reviewed	-	CYP2C19	Potency	'='	398	nM
P10636	BXGT007596	Microtubule-associated protein tau	reviewed	-	MAPT	Potency	'='	1122	nM
Q9NUW8	BXGT021219	Tyrosyl-DNA phosphodiesterase 1	reviewed	Enzyme	TDP1	Potency	-	8199	nM
O15118	BXGT004127	NPC intracellular cholesterol transporter 1	reviewed	Transporter	NPC1	Potency	'='	5623	nM
Q96QE3	BXGT019718	ATPase family AAA domain-containing protein 5	reviewed	-	ATAD5	Potency	-	23099	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	Kd	'='	6309	nM
P11712	BXGT007738	Cytochrome P450 2C9	reviewed	-	CYP2C9	Potency	'='	2511	nM
Q03431	BXGT012714	Parathyroid hormone/parathyroid hormone-related peptide receptor	reviewed	G-protein coupled receptor	PTH1R	Potency	-	50118	nM
P10636	BXGT007596	Microtubule-associated protein tau	reviewed	-	MAPT	Potency	'='	4466	nM
P08659	BXGT006805	Luciferin 4-monooxygenase	reviewed	-		Potency	-	15101	nM
Q16236	BXGT013624	Nuclear factor erythroid 2-related factor 2	reviewed	Enzyme	NFE2L2	Potency	-	35481	nM
O95398	BXGT005378	Rap guanine nucleotide exchange factor 3	reviewed	Enzyme modulator	RAPGEF3	Potency	-	39810	nM
P37840	BXGT010015	Alpha-synuclein	reviewed	Transporter	SNCA	Potency	-	6309	nM

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF00074	Cardamom	Elettaria cardamomum	Herbs and Spices
BXGF00138	Pine nut	Pinus	Nuts
BXGF00143	Prunus (Cherry, Plum)	Prunus	Fruits
BXGF00145	Sweet cherry	Prunus avium	Fruits
BXGF00146	Sour cherry	Prunus cerasus	Fruits
BXGF00900	Melaleuca cuticularis	Melaleuca cuticularis	Others
BXGF01044	Bellardia viscosa	Bellardia viscosa	Others
BXGF01104	Garcinia cambogia	Garcinia cambogia	Medicinal Plant
BXGF01250	Colchicum filifolium	Colchicum filifolium	Others
BXGF01252	Petasites laevigatus	Petasites laevigatus	Medicinal Plant
BXGF01256	Cynoglossum macrostylum	Cynoglossum macrostylum	Others
BXGF01404	Sphaeranthus confertifolius	Sphaeranthus confertifolius	Others
BXGF01556	Ornithoglossum viride	Ornithoglossum viride	Others
BXGF01606	Schizanthus tricolor	Schizanthus tricolor	Others
BXGF01631	Anodendron affine	Anodendron affine	Medicinal Plant
BXGF01669	Hertia cheirifolia	Hertia cheirifolia	Others
BXGF01686	Pulsatilla chinensis	Pulsatilla chinensis	Medicinal Plant
BXGF01720	Cedrela salvadorensis	Cedrela salvadorensis	Others
BXGF01775	Phagnalon rupestre	Phagnalon rupestre	Medicinal Plant
BXGF02206	Mucuna holtonii	Mucuna holtonii	Others
BXGF02233	Quercus marilandica	Quercus marilandica	Medicinal Plant
BXGF02328	Dalbergia nitidula	Dalbergia nitidula	Medicinal Plant
BXGF02333	Saposhnikovia divaricata	Saposhnikovia divaricata	Medicinal Plant
BXGF02437	Piliostigma thonningii	Piliostigma thonningii	Medicinal Plant
BXGF02446	Centaurea scoparia	Centaurea scoparia	Others
BXGF02461	Kopsia lapidilecta	Kopsia lapidilecta	Others
BXGF02492	Dryopteris arguta	Dryopteris arguta	Human Edible Plant
BXGF02771	Plenckia populnea	Plenckia populnea	Others
BXGF02775	Aconitum contortum	Aconitum contortum	Others
BXGF02938	Uvaria lucida	Uvaria lucida	Human Edible Plant
BXGF03054	Mimosa pigra	Mimosa pigra	Medicinal Plant
BXGF03103	Cheilanthes fragrans	Cheilanthes fragrans	Medicinal Plant
BXGF03216	Neolitsea villosa	Neolitsea villosa	Others
BXGF03239	Fadogia agrestis	Fadogia agrestis	Medicinal Plant
BXGF03289	Ostrya carpinifolia	Ostrya carpinifolia	Medicinal Plant
BXGF03293	Crinum giganteum	Crinum giganteum	Others
BXGF03305	Aconitum variegatum	Aconitum variegatum	Medicinal Plant
BXGF03333	Nuxia sphaerocephala	Nuxia sphaerocephala	Medicinal Plant
BXGF03454	Saussurea salicifolia	Saussurea salicifolia	Others
BXGF03477	Stephania dielsiana	Stephania dielsiana	Medicinal Plant
BXGF03507	Pinus aristata	Pinus aristata	Medicinal Plant
BXGF03527	Alpinia oxyphylla	Alpinia oxyphylla	Medicinal Plant
BXGF03591	Ammodendron karelinii	Ammodendron karelinii	Others
BXGF03600	Callistemon coccineus	Callistemon coccineus	Others
BXGF03601	Maclura cochinchinensis	Maclura cochinchinensis	Medicinal Plant
BXGF03622	Justicia betonica	Justicia betonica	Medicinal Plant
BXGF03636	Hypericum reptans	Hypericum reptans	Others
BXGF03655	Uncaria africana	Uncaria africana	Medicinal Plant
BXGF03670	Strychnos amazonica	Strychnos amazonica	Medicinal Plant
BXGF03687	Alpinia zerumbet	Alpinia zerumbet	Medicinal Plant
BXGF03701	Escontria chiotilla	Escontria chiotilla	Human Edible Plant
BXGF03719	Rubus laciniatus	Rubus laciniatus	Medicinal Plant
BXGF03752	Buglossoides arvensis	Buglossoides arvensis	Medicinal Plant
BXGF03755	Eucryphia cordifolia	Eucryphia cordifolia	Others
BXGF03770	Buxus hildebrandtii	Buxus hildebrandtii	Others
BXGF03778	Drypetes tessmanniana	Drypetes tessmanniana	Others
BXGF03790	Pteryxia terebinthina	Pteryxia terebinthina	Others
BXGF03805	Gratiola officinalis	Gratiola officinalis	Medicinal Plant
BXGF03818	Rhizophora tagal	Rhizophora tagal	Others
BXGF03825	Salvia lavandulifolia	Salvia lavandulifolia	Medicinal Plant
BXGF03835	Echinacea simulata	Echinacea simulata	Others
BXGF03850	Cotinus coggygria	Cotinus coggygria	Medicinal Plant
BXGF03854	Grindelia discoidea	Grindelia discoidea	Others
BXGF03869	Eremurus chinensis	Eremurus chinensis	Others
BXGF03900	Pachygone dasycarpa	Pachygone dasycarpa	Others
BXGF03905	Croton geayi	Croton geayi	Others
BXGF03918	Callicarpa acuminata	Callicarpa acuminata	Human Edible Plant
BXGF03923	Ageratum mexicanum	Ageratum mexicanum	Others
BXGF03936	Petunia nyctaginiflora	Petunia nyctaginiflora	Medicinal Plant
BXGF03956	Arnica parryi	Arnica parryi	Others
BXGF03983	Kalanchoe spathulata	Kalanchoe spathulata	Medicinal Plant
BXGF04035	Campanula choziatowskyi	Campanula choziatowskyi	Others
BXGF04208	Salvia patens	Salvia patens	Others
BXGF04214	Dialium excelsum	Dialium excelsum	Others
BXGF04372	Kniphofia foliosa	Kniphofia foliosa	Human Edible Plant
BXGF04380	Euphorbia hylonoma	Euphorbia hylonoma	Others
BXGF04409	Senecio platyphylloides	Senecio platyphylloides	Others
BXGF04418	Drymaria cordata	Drymaria cordata	Medicinal Plant
BXGF04442	Boesenbergia pandurata	Boesenbergia pandurata	Medicinal Plant
BXGF04447	Helleborus macranthus	Helleborus macranthus	Others
BXGF04448	Salix rosmarinifolia	Salix rosmarinifolia	Others
BXGF04455	Heliotropium scabrum	Heliotropium scabrum	Others
BXGF04457	Podocarpus dacrydioides	Podocarpus dacrydioides	Medicinal Plant
BXGF04469	Centaurea sonchifolia	Centaurea sonchifolia	Others
BXGF04472	Matricaria sabulosa	Matricaria sabulosa	Others
BXGF04489	Pterocaulon serrulatum	Pterocaulon serrulatum	Medicinal Plant
BXGF04502	Mimusops laurifolia	Mimusops laurifolia	Human Edible Plant
BXGF04504	Boswellia ovalifoliolata	Boswellia ovalifoliolata	Medicinal Plant
BXGF04515	Hardenbergia violacea	Hardenbergia violacea	Medicinal Plant
BXGF04529	Lonchocarpus chiricanus	Lonchocarpus chiricanus	Others
BXGF04530	Salvia pisidica	Salvia pisidica	Medicinal Plant
BXGF04533	Astragalus circassicus	Astragalus circassicus	Others
BXGF04543	Erythrina hypaphorus	Erythrina hypaphorus	Others
BXGF04548	Beilschmiedia madang	Beilschmiedia madang	Medicinal Plant
BXGF04549	Pentachondra pumila	Pentachondra pumila	Medicinal Plant
BXGF04555	Salvia lavanduloides	Salvia lavanduloides	Others
BXGF04565	Ursinia speciosa	Ursinia speciosa	Others
BXGF04573	Rubia akane	Rubia akane	Medicinal Plant
BXGF04575	Anacyclus pyrethrum	Anacyclus pyrethrum	Medicinal Plant
BXGF04581	Brachylaena perrieri	Brachylaena perrieri	Others
BXGF04586	Aniba santalodora	Aniba santalodora	Others
BXGF04596	Diplotropis ferruginea	Diplotropis ferruginea	Others
BXGF04604	Viguiera pinnatilobata	Viguiera pinnatilobata	Others
BXGF04608	Phlomis ostrowskiana	Phlomis ostrowskiana	Others
BXGF04618	Mentzelia decapetala	Mentzelia decapetala	Human Edible Plant
BXGF04622	Uncaria longiflora	Uncaria longiflora	Medicinal Plant
BXGF04628	Pimpinella peregrina	Pimpinella peregrina	Human Edible Plant
BXGF04648	Amorphophallus konjac	Amorphophallus konjac	Human Edible Plant
BXGF04649	Medicosma fareana	Medicosma fareana	Others
BXGF04656	Solanum crinitum	Solanum crinitum	Others
BXGF04663	Mentha sylvestris	Mentha sylvestris	Medicinal Plant
BXGF04668	Euphrasia regelii	Euphrasia regelii	Medicinal Plant
BXGF04671	Hortonia angustifolia	Hortonia angustifolia	Others
BXGF04688	Julbernardia globifera	Julbernardia globifera	Others
BXGF04691	Oroxylum indicum	Oroxylum indicum	Medicinal Plant
BXGF04697	Phlox decussata	Phlox decussata	Others
BXGF04704	Tubocapsicum anomalum	Tubocapsicum anomalum	Human Edible Plant
BXGF04711	Cuscuta australis	Cuscuta australis	Medicinal Plant
BXGF04713	Aster tataricus	Aster tataricus	Medicinal Plant
BXGF04717	Salvia lanigera	Salvia lanigera	Medicinal Plant
BXGF04722	Othonna macrophylla	Othonna macrophylla	Others
BXGF04724	Miliusa balansae	Miliusa balansae	Others
BXGF04726	Eucalyptus viminalis	Eucalyptus viminalis	Medicinal Plant
BXGF04732	Laggera pterodonta	Laggera pterodonta	Medicinal Plant
BXGF04740	Acronychia haplophylla	Acronychia haplophylla	Medicinal Plant
BXGF04745	Salix petiolaris	Salix petiolaris	Others
BXGF04750	Scutellaria baicalensis	Scutellaria baicalensis	Medicinal Plant
BXGF04752	Pinus monticola	Pinus monticola	Medicinal Plant
BXGF04763	Myrrhis odorata	Myrrhis odorata	Medicinal Plant
BXGF04849	Pinus excelsa	Pinus excelsa	Medicinal Plant
BXGF04897	Alstonia spectabilis	Alstonia spectabilis	Medicinal Plant
BXGF04947	Derris indica	Derris indica	Medicinal Plant
BXGF05231	Salvia virgata	Salvia virgata	Human Edible Plant
BXGF05436	Rubia tetragona	Rubia tetragona	Others
BXGF05459	Vachellia pennatula	Vachellia pennatula	Medicinal Plant
BXGF05566	Petunia axillaris subsp. parodii	Petunia axillaris subsp. parodii	Medicinal Plant
BXGF05858	Ormosia hosiei	Ormosia hosiei	Medicinal Plant
BXGF06122	Bethencourtia palmensis	Bethencourtia palmensis	Others
BXGF06203	Lepechinia urbanii	Lepechinia urbanii	Others
BXGF06250	Licaria chrysophylla	Licaria chrysophylla	Others
BXGF06298	Hippocrepis emerus	Hippocrepis emerus	Others
BXGF06301	Oricia gabonensis	Oricia gabonensis	Others

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}