acompound

Showing entry for 2'-Methylisoliquiritigenin

General Compound Information
BXGC Id	BXGC0008710
Compound Name	2'-Methylisoliquiritigenin
Structure
Formula	C16H14O4
InchiKey	PACBGANPVNHGNP-RUDMXATFSA-N
SMILES	COC1=C(C=CC(O)=C1)C(=O)\C=C\C1=CC=C(O)C=C1
Inchi	InChI=1S/C16H14O4/c1-20-16-10-13(18)7-8-14(16)15(19)9-4-11-2-5-12(17)6-3-11/h2-10,17-18H,1H3/b9-4+
IUPAC	(2E)-1-(4-hydroxy-2-methoxyphenyl)-3-(4-hydroxyphenyl)prop-2-en-1-one
Molecular Weight	270.28
Pubchem Id	5319688
Chembl Id	CHEMBL253777

Targets of Information Source

DrugBank

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type

PDB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1

Binding DB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM

CHEMBL

CHEMBL253777

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
B4URF0	BXGT002146	Neuraminidase	unreviewed	-	NA	IC50	'='	24300	nM
P00533	BXGT005575	Epidermal growth factor receptor	reviewed	Kinase	EGFR	Inhibition	'='	0	%
P12931	BXGT007859	Proto-oncogene tyrosine-protein kinase Src	reviewed	Kinase	SRC	Inhibition	'='	1	%
P08581	BXGT006794	Hepatocyte growth factor receptor	reviewed	Kinase	MET	Inhibition	-	-	-
P35968	BXGT009887	Vascular endothelial growth factor receptor 2	reviewed	Kinase	KDR	Inhibition	'='	12	%
P21802	BXGT008691	Fibroblast growth factor receptor 2	reviewed	Kinase	FGFR2	Inhibition	'='	0	%
P10721	BXGT007605	Mast/stem cell growth factor receptor Kit	reviewed	Kinase	KIT	Inhibition	'='	1	%
P11362	BXGT007693	Fibroblast growth factor receptor 1	reviewed	Kinase	FGFR1	Inhibition	'='	28	%

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF00141	Common pea	Pisum sativum	Pulses
BXGF00199	Gram bean	Vigna mungo	Pulses
BXGF00503	Rowal	Pangium edule	Herbs and Spices
BXGF00819	Pulses		Pulses
BXGF00857	Mitracarpus scaber	Mitracarpus scaber	Others
BXGF01051	Callicarpa japonica	Callicarpa japonica	Medicinal Plant
BXGF01061	Avrainvillea longicaulis	Avrainvillea longicaulis	Others
BXGF01460	Dracaena cochinchinensis	Dracaena cochinchinensis	Medicinal Plant
BXGF01539	Euphrasia stricta	Euphrasia stricta	Others
BXGF01599	Helichrysum cephaloideum	Helichrysum cephaloideum	Medicinal Plant
BXGF01684	Hemionitis japonica	Hemionitis japonica	Others
BXGF01793	Sedum obtuso-lineare	Sedum obtuso-lineare	Others
BXGF01890	Trollius chinensis	Trollius chinensis	Medicinal Plant
BXGF02053	Hypericum balearicum	Hypericum balearicum	Others
BXGF02155	Chrysanthemum uliginosum	Chrysanthemum uliginosum	Others
BXGF02199	Bryum argenteum	Bryum argenteum	Medicinal Plant
BXGF02341	Euphorbia amygdaloides	Euphorbia amygdaloides	Medicinal Plant
BXGF02380	Entada phaseoloides	Entada phaseoloides	Medicinal Plant
BXGF02421	Hesperis matronalis	Hesperis matronalis	Medicinal Plant
BXGF02449	Jatropha macrorhiza	Jatropha macrorhiza	Others
BXGF02540	Jackiella javanica	Jackiella javanica	Medicinal Plant
BXGF02587	Rhus vulgaris	Rhus vulgaris	Human Edible Plant
BXGF02610	Cladrastis platycarpa	Cladrastis platycarpa	Others
BXGF02626	Dalbergia odorifera	Dalbergia odorifera	Medicinal Plant
BXGF02646	Eremanthus seidelii	Eremanthus seidelii	Others
BXGF02732	Senecio adenophyllus	Senecio adenophyllus	Others
BXGF02768	Lilium umbellatum	Lilium umbellatum	Others
BXGF02784	Artemisia rehan	Artemisia rehan	Others
BXGF02807	Elephantopus hirtiflorus	Elephantopus hirtiflorus	Others
BXGF02828	Nematolepis phebalioides	Nematolepis phebalioides	Others
BXGF02839	Solidago flexicaulis	Solidago flexicaulis	Human Edible Plant
BXGF02854	Ligularia cymbulifera	Ligularia cymbulifera	Others
BXGF02877	Coprosma areolata	Coprosma areolata	Medicinal Plant
BXGF02907	Oreopteris quelpaertensis	Oreopteris quelpaertensis	Others
BXGF02940	Conyza japonica	Conyza japonica	Medicinal Plant
BXGF02948	Viguiera linearis	Viguiera linearis	Others
BXGF03142	Soymida febrifuga	Soymida febrifuga	Medicinal Plant
BXGF03313	Magnolia montana	Magnolia montana	Medicinal Plant
BXGF03346	Dendrobium candidum	Dendrobium candidum	Others
BXGF03504	Sterculia foetida	Sterculia foetida	Medicinal Plant
BXGF03672	Erysimum siliculosum	Erysimum siliculosum	Others
BXGF04046	Biancaea sappan	Biancaea sappan	Medicinal Plant
BXGF04255	Gmelina asiatica	Gmelina asiatica	Medicinal Plant
BXGF04659	Phyllanthus emblica	Phyllanthus emblica	Medicinal Plant
BXGF04923	Caesalpinia sappan	Caesalpinia sappan	Medicinal Plant
BXGF05285	Aglaia formosana	Aglaia formosana	Others
BXGF05720	Camchaya loloana	Camchaya loloana	Others
BXGF05790	Glycyrrhiza uralensis	Glycyrrhiza uralensis	Medicinal Plant
BXGF06115	Kaempferia rotunda	Kaempferia rotunda	Medicinal Plant

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}