acompound

Showing entry for Tetramethylquercetin

General Compound Information
BXGC Id	BXGC0009207
Compound Name	Tetramethylquercetin
Structure
Formula	C19H18O7
InchiKey	HHGPYJLEJGNWJA-UHFFFAOYSA-N
SMILES	COC1=CC(O)=C2C(=O)C(OC)=C(OC2=C1)C1=CC=C(OC)C(OC)=C1
Inchi	InChI=1S/C19H18O7/c1-22-11-8-12(20)16-15(9-11)26-18(19(25-4)17(16)21)10-5-6-13(23-2)14(7-10)24-3/h5-9,20H,1-4H3
IUPAC	2-(3,4-dimethoxyphenyl)-5-hydroxy-3,7-dimethoxy-4H-chromen-4-one
Molecular Weight	358.34
Pubchem Id	5352005
Chembl Id	CHEMBL77966

Targets of Information Source

DrugBank

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type

PDB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1

Binding DB

50338974

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
reviewed	BXGT009728	Multidrug resistance-associated protein 1	reviewed	Transporter	ABCC1	-	50000	-	-
reviewed	BXGT021792	ATP-binding cassette sub-family G member 2	reviewed	Transporter	ABCG2	-	390	-	-
reviewed	BXGT021792	ATP-binding cassette sub-family G member 2	reviewed	Transporter	ABCG2	-	900	-	-
reviewed	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	-	16000	-	-
reviewed	BXGT021792	ATP-binding cassette sub-family G member 2	reviewed	Transporter	ABCG2	-	570	-	-
reviewed	BXGT021792	ATP-binding cassette sub-family G member 2	reviewed	Transporter	ABCG2	-	540	-	-

CHEMBL

CHEMBL77966

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
Q28731	BXGT013954	Thrombin	unreviewed	-	thrombin	PT	'='	5	s
Q9UNQ0	BXGT021792	ATP-binding cassette sub-family G member 2	reviewed	Transporter	ABCG2	Inhibition	-	-	-
Q9UNQ0	BXGT021792	ATP-binding cassette sub-family G member 2	reviewed	Transporter	ABCG2	FC	'='	19	-
Q9UNQ0	BXGT021792	ATP-binding cassette sub-family G member 2	reviewed	Transporter	ABCG2	IC50	'='	900	nM
P08183	BXGT006741	ATP-dependent translocase ABCB1	reviewed	Transporter	ABCB1	IC50	'='	16000	nM
P33527	BXGT009728	Multidrug resistance-associated protein 1	reviewed	Transporter	ABCC1	IC50	'='	50000	nM
Q9UNQ0	BXGT021792	ATP-binding cassette sub-family G member 2	reviewed	Transporter	ABCG2	IC50	'='	390	nM
Q965D6	BXGT019601	3-oxoacyl-acyl-carrier protein reductase	unreviewed	-	fabG	Activity	-	-	-
P33527	BXGT009728	Multidrug resistance-associated protein 1	reviewed	Transporter	ABCC1	FC	'='	0	-
Q86831	BXGT017584	Polyprotein II	unreviewed	-		Inhibition	'='	9	%
Q965D5	BXGT019600	Enoyl-acyl-carrier protein reductase	unreviewed	-	fabI	Activity	-	-	-
Q965D7	BXGT019602	Beta-hydroxyacyl-ACP dehydratase	unreviewed	-	fabZ	Activity	-	-	-
Q9UNQ0	BXGT021792	ATP-binding cassette sub-family G member 2	reviewed	Transporter	ABCG2	IC50	'='	540	nM
Q9UNQ0	BXGT021792	ATP-binding cassette sub-family G member 2	reviewed	Transporter	ABCG2	FC	'='	13	-
Q28731	BXGT013954	Thrombin	unreviewed	-	thrombin	APTT	'='	42	s
Q28731	BXGT013954	Thrombin	unreviewed	-	thrombin	Activity	'='	8	g/L
Q28731	BXGT013954	Thrombin	unreviewed	-	thrombin	TT	'='	14	s
Q9UNQ0	BXGT021792	ATP-binding cassette sub-family G member 2	reviewed	Transporter	ABCG2	IC50	'='	570	nM

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF00056	Mandarin orange (Clementine, Tangerine)	Citrus reticulata	Fruits
BXGF00124	Common oregano	Origanum vulgare	Herbs and Spices
BXGF00966	Tristania conferta	Tristania conferta	Others
BXGF00972	Plectranthus myrianthus	Plectranthus myrianthus	Others
BXGF01024	Pentaclethra macrophylla	Pentaclethra macrophylla	Medicinal Plant
BXGF01085	Veronica polita	Veronica polita	Medicinal Plant
BXGF01183	Glycosmis macrophylla	Glycosmis macrophylla	Others
BXGF01250	Colchicum filifolium	Colchicum filifolium	Others
BXGF01253	Stephania zippeliana	Stephania zippeliana	Others
BXGF01256	Cynoglossum macrostylum	Cynoglossum macrostylum	Others
BXGF01329	Eucalyptus apodophylla	Eucalyptus apodophylla	Medicinal Plant
BXGF01416	Hypericum polyanthemum	Hypericum polyanthemum	Others
BXGF01418	Distephanus angulifolius	Distephanus angulifolius	Others
BXGF01480	Periploca sepium	Periploca sepium	Medicinal Plant
BXGF01548	Campylotropis hirtella	Campylotropis hirtella	Medicinal Plant
BXGF01686	Pulsatilla chinensis	Pulsatilla chinensis	Medicinal Plant
BXGF02206	Mucuna holtonii	Mucuna holtonii	Others
BXGF02233	Quercus marilandica	Quercus marilandica	Medicinal Plant
BXGF02351	Libanothamnus occultus	Libanothamnus occultus	Others
BXGF02446	Centaurea scoparia	Centaurea scoparia	Others
BXGF02633	Breonia chinensis	Breonia chinensis	Medicinal Plant
BXGF03043	Melicope semecarpifolia	Melicope semecarpifolia	Medicinal Plant
BXGF03054	Mimosa pigra	Mimosa pigra	Medicinal Plant
BXGF03103	Cheilanthes fragrans	Cheilanthes fragrans	Medicinal Plant
BXGF03209	Senecio retrorsus	Senecio retrorsus	Medicinal Plant
BXGF03239	Fadogia agrestis	Fadogia agrestis	Medicinal Plant
BXGF03289	Ostrya carpinifolia	Ostrya carpinifolia	Medicinal Plant
BXGF03305	Aconitum variegatum	Aconitum variegatum	Medicinal Plant
BXGF03477	Stephania dielsiana	Stephania dielsiana	Medicinal Plant
BXGF03514	Pteris bella	Pteris bella	Medicinal Plant
BXGF03518	Mentha cardiaca	Mentha cardiaca	Others
BXGF03601	Maclura cochinchinensis	Maclura cochinchinensis	Medicinal Plant
BXGF03626	Trichilia heudelotii	Trichilia heudelotii	Others
BXGF03637	Rhodiola semenovii	Rhodiola semenovii	Others
BXGF03644	Andromeda polifolia	Andromeda polifolia	Medicinal Plant
BXGF03753	Scapania bolanderi	Scapania bolanderi	Others
BXGF03776	Argyrochosma pilifera	Argyrochosma pilifera	Others
BXGF03836	Gymnopetalum integrifolium	Gymnopetalum integrifolium	Medicinal Plant
BXGF03852	Genista lydia	Genista lydia	Others
BXGF03959	Vincetoxicum forrestii	Vincetoxicum forrestii	Others
BXGF04035	Campanula choziatowskyi	Campanula choziatowskyi	Others
BXGF04208	Salvia patens	Salvia patens	Others
BXGF04214	Dialium excelsum	Dialium excelsum	Others
BXGF04380	Euphorbia hylonoma	Euphorbia hylonoma	Others
BXGF04409	Senecio platyphylloides	Senecio platyphylloides	Others
BXGF04418	Drymaria cordata	Drymaria cordata	Medicinal Plant
BXGF04442	Boesenbergia pandurata	Boesenbergia pandurata	Medicinal Plant
BXGF04447	Helleborus macranthus	Helleborus macranthus	Others
BXGF04448	Salix rosmarinifolia	Salix rosmarinifolia	Others
BXGF04455	Heliotropium scabrum	Heliotropium scabrum	Others
BXGF04457	Podocarpus dacrydioides	Podocarpus dacrydioides	Medicinal Plant
BXGF04469	Centaurea sonchifolia	Centaurea sonchifolia	Others
BXGF04472	Matricaria sabulosa	Matricaria sabulosa	Others
BXGF04489	Pterocaulon serrulatum	Pterocaulon serrulatum	Medicinal Plant
BXGF04504	Boswellia ovalifoliolata	Boswellia ovalifoliolata	Medicinal Plant
BXGF04515	Hardenbergia violacea	Hardenbergia violacea	Medicinal Plant
BXGF04529	Lonchocarpus chiricanus	Lonchocarpus chiricanus	Others
BXGF04533	Astragalus circassicus	Astragalus circassicus	Others
BXGF04543	Erythrina hypaphorus	Erythrina hypaphorus	Others
BXGF04548	Beilschmiedia madang	Beilschmiedia madang	Medicinal Plant
BXGF04555	Salvia lavanduloides	Salvia lavanduloides	Others
BXGF04573	Rubia akane	Rubia akane	Medicinal Plant
BXGF04586	Aniba santalodora	Aniba santalodora	Others
BXGF04618	Mentzelia decapetala	Mentzelia decapetala	Human Edible Plant
BXGF04648	Amorphophallus konjac	Amorphophallus konjac	Human Edible Plant
BXGF04889	Pogostemon cablin	Pogostemon cablin	Medicinal Plant
BXGF05081	Agastache rugosus	Agastache rugosus	Medicinal Plant
BXGF05137	Acalypha australis	Acalypha australis	Medicinal Plant
BXGF05170	Crotalaria candicans	Crotalaria candicans	Others
BXGF05231	Salvia virgata	Salvia virgata	Human Edible Plant
BXGF05385	Eria japonica	Eria japonica	Others
BXGF05427	Salvia sessei	Salvia sessei	Others
BXGF05466	Juniperus drupacea	Juniperus drupacea	Medicinal Plant
BXGF05566	Petunia axillaris subsp. parodii	Petunia axillaris subsp. parodii	Medicinal Plant
BXGF05615	Ceropegia dichotoma	Ceropegia dichotoma	Garden Plant
BXGF05708	Ononis spinosa	Ononis spinosa	Medicinal Plant
BXGF05903	Crinum moorei	Crinum moorei	Others
BXGF05913	Eucalyptus globulus subsp. bicostata	Eucalyptus globulus subsp. bicostata	Medicinal Plant
BXGF06069	Dendrobium loddigesii	Dendrobium loddigesii	Medicinal Plant
BXGF06119	Gypsophila perfoliata	Gypsophila perfoliata	Others
BXGF06122	Bethencourtia palmensis	Bethencourtia palmensis	Others
BXGF06195	Pterocaulon virgatum	Pterocaulon virgatum	Medicinal Plant
BXGF06203	Lepechinia urbanii	Lepechinia urbanii	Others
BXGF06241	Vernonia cistifolia	Vernonia cistifolia	Others
BXGF06274	Sonneratia caseolaris	Sonneratia caseolaris	Medicinal Plant

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}