Showing entry for Cytokinin B


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0010354
Compound NameCytokinin B
Structure
FormulaC12H11N5
InchiKeyNWBJYWHLCVSVIJ-UHFFFAOYSA-N
SMILESC(NC1=C2N=CNC2=NC=N1)C1=CC=CC=C1
InchiInChI=1S/C12H11N5/c1-2-4-9(5-3-1)6-13-11-10-12(15-7-14-10)17-8-16-11/h1-5,7-8H,6H2,(H2,13,14,15,16,17)
IUPACN-benzyl-9H-purin-6-amine
Molecular Weight225.25
Pubchem Id62389
Chembl IdCHEMBL228862
Targets of Information Source
DrugBank n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
PDB EMU
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Q9T0N8 BXGT021617 Cytokinin dehydrogenase 1 reviewed CKX1 - - - - -
Q9C5U0 BXGT020221 Histidine kinase 4 reviewed AHK4 - - - - -
P93330 BXGT012120 Nodulin-13 reviewed N13 - - - - -
P28482 BXGT009263 Mitogen-activated protein kinase 1 reviewed MAPK1 Kinase - - - -
P00517 BXGT005568 cAMP-dependent protein kinase catalytic subunit alpha reviewed PRKACA - - - - -
Binding DB 50205363
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
reviewed BXGT006445 Cyclin-dependent kinase 1 reviewed Kinase CDK1 - 200000 - -
reviewed BXGT009263 Mitogen-activated protein kinase 1 reviewed Kinase MAPK1 - - 247000 -
reviewed BXGT020127 Phosphatidylinositol 4-kinase type 2-alpha reviewed Kinase PI4K2A 199000 - - -
reviewed BXGT020127 Phosphatidylinositol 4-kinase type 2-alpha reviewed Kinase PI4K2A - 240400 - -
CHEMBL CHEMBL228862
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
P16473 BXGT008234 Thyrotropin receptor reviewed G-protein coupled receptor TSHR Potency '=' 1995 nM
O75496 BXGT005132 Geminin reviewed - GMNN Potency - 891 nM
P27695 BXGT009199 DNA-(apurinic or apyrimidinic site) lyase reviewed - APEX1 Potency - 10 nM
P28482 BXGT009263 Mitogen-activated protein kinase 1 reviewed Kinase MAPK1 Kd '=' 247000 nM
P10635 BXGT007595 Cytochrome P450 2D6 reviewed - CYP2D6 AC50 '=' 12589 nM
P42356 BXGT010305 Phosphatidylinositol 4-kinase alpha reviewed Kinase PI4KA Ki '=' 199000 nM
Q9UBF8 BXGT021653 Phosphatidylinositol 4-kinase beta reviewed Kinase PI4KB Ki '=' 199000 nM
Q8TCG2 BXGT018798 Phosphatidylinositol 4-kinase type 2-beta reviewed Enzyme PI4K2B Ki '=' 199000 nM
Q9BTU6 BXGT020127 Phosphatidylinositol 4-kinase type 2-alpha reviewed Kinase PI4K2A Ki '=' 199000 nM
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 35481 nM
P06493 BXGT006445 Cyclin-dependent kinase 1 reviewed Kinase CDK1 IC50 '=' 200000 nM
P42356 BXGT010305 Phosphatidylinositol 4-kinase alpha reviewed Kinase PI4KA IC50 '=' 240400 nM
Q9UBF8 BXGT021653 Phosphatidylinositol 4-kinase beta reviewed Kinase PI4KB IC50 '=' 240400 nM
Q8TCG2 BXGT018798 Phosphatidylinositol 4-kinase type 2-beta reviewed Enzyme PI4K2B IC50 '=' 240400 nM
Q9BTU6 BXGT020127 Phosphatidylinositol 4-kinase type 2-alpha reviewed Kinase PI4K2A IC50 '=' 240400 nM
P02791 BXGT005965 Ferritin light chain reviewed - FTL Potency '=' 50118 nM
Q9T0N8 BXGT021617 Cytokinin dehydrogenase 1 reviewed - CKX1 Km '=' 29600 nM
P42356 BXGT010305 Phosphatidylinositol 4-kinase alpha reviewed Kinase PI4KA Km '=' 239000 nM
Q9UBF8 BXGT021653 Phosphatidylinositol 4-kinase beta reviewed Kinase PI4KB Km '=' 239000 nM
Q8TCG2 BXGT018798 Phosphatidylinositol 4-kinase type 2-beta reviewed Enzyme PI4K2B Km '=' 239000 nM
Q9BTU6 BXGT020127 Phosphatidylinositol 4-kinase type 2-alpha reviewed Kinase PI4K2A Km '=' 239000 nM
P05177 BXGT006336 Cytochrome P450 1A2 reviewed Enzyme CYP1A2 AC50 '=' 5011 nM
Q9T0N8 BXGT021617 Cytokinin dehydrogenase 1 reviewed - CKX1 Kcat '=' 0 /s
P02545 BXGT005889 Prelamin-A/C reviewed - LMNA Potency '=' 3162 nM
P11712 BXGT007738 Cytochrome P450 2C9 reviewed - CYP2C9 AC50 - - -
P33261 BXGT009707 Cytochrome P450 2C19 reviewed - CYP2C19 AC50 - - -
P10635 BXGT007595 Cytochrome P450 2D6 reviewed - CYP2D6 Potency '=' 12589 nM
P24941 BXGT009002 Cyclin-dependent kinase 2 reviewed Kinase CDK2 Kd '=' 62000 nM
P49902 BXGT010758 Cytosolic purine 5'-nucleotidase reviewed Enzyme NT5C2 Inhibition '=' 20 %
Q9T0N8 BXGT021617 Cytokinin dehydrogenase 1 reviewed - CKX1 Kcat/Km '=' 0 -
P08684 BXGT006812 Cytochrome P450 3A4 reviewed Enzyme CYP3A4 AC50 - - -
O60885 BXGT004906 Bromodomain-containing protein 4 reviewed Epigenetic regulator BRD4 Inhibition - - -
P24941 BXGT009002 Cyclin-dependent kinase 2 reviewed Kinase CDK2 Activity - - -
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF00015 Wild celery Apium graveolens Herbs and Spices
BXGF00173 Garden tomato (var.) Solanum lycopersicum var. lycopersicum Vegetables
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease