acompound

Showing entry for tetrahydropalmatine

General Compound Information
BXGC Id	BXGC0013190
Compound Name	tetrahydropalmatine
Structure
Formula	C21H25NO4
InchiKey	AEQDJSLRWYMAQI-QGZVFWFLSA-N
SMILES	COc1cc2CCN3[C@@H](c2cc1OC)Cc1c(C3)c(OC)c(cc1)OC
Inchi	InChI=1S/C21H25NO4/c1-23-18-6-5-13-9-17-15-11-20(25-3)19(24-2)10-14(15)7-8-22(17)12-16(13)21(18)26-4/h5-6,10-11,17H,7-9,12H2,1-4H3/t17-/m1/s1
IUPAC	(13aR)-2,3,9,10-tetramethoxy-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinoline
Molecular Weight	355.18
Pubchem Id	969488
Chembl Id	CHEMBL2334889

Targets of Information Source

DrugBank

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type

PDB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1

Binding DB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM

CHEMBL

CHEMBL2334889

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
P28223	BXGT009239	5-hydroxytryptamine receptor 2A	reviewed	G-protein coupled receptor	HTR2A	Inhibition	'='	29	%
P21728	BXGT008686	D(1A) dopamine receptor	reviewed	G-protein coupled receptor	DRD1	Ki	-	-	-
P14416	BXGT008011	D(2) dopamine receptor	reviewed	G-protein coupled receptor	DRD2	Ki	-	-	-
P08908	BXGT006837	5-hydroxytryptamine receptor 1A	reviewed	G-protein coupled receptor	HTR1A	Inhibition	'='	30	%
P14416	BXGT008011	D(2) dopamine receptor	reviewed	G-protein coupled receptor	DRD2	Inhibition	'='	20	%
P21728	BXGT008686	D(1A) dopamine receptor	reviewed	G-protein coupled receptor	DRD1	Inhibition	'='	39	%
P08908	BXGT006837	5-hydroxytryptamine receptor 1A	reviewed	G-protein coupled receptor	HTR1A	Ki	-	-	-
P28223	BXGT009239	5-hydroxytryptamine receptor 2A	reviewed	G-protein coupled receptor	HTR2A	Ki	-	-	-

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF01696	Coptis japonica	Coptis japonica	Medicinal Plant
BXGF01731	Corydalis turtschaninovii	Corydalis turtschaninovii	Human Edible Plant
BXGF01752	Corydalis decumbens	Corydalis decumbens	Medicinal Plant
BXGF02810	Passiflora coccinea	Passiflora coccinea	Human Edible Plant
BXGF03427	Phellodendron chinense	Phellodendron chinense	Medicinal Plant
BXGF03498	Coptis deltoidea	Coptis deltoidea	Medicinal Plant
BXGF03535	Horsfieldia iryaghedhi	Horsfieldia iryaghedhi	Others
BXGF03640	Fibraurea recisa	Fibraurea recisa	Medicinal Plant
BXGF03642	Karwinskia subcordata	Karwinskia subcordata	Others
BXGF03651	Medicago hispida	Medicago hispida	Human Edible Plant
BXGF03673	Maytenus octogona	Maytenus octogona	Others
BXGF03728	Agathosma bisulca	Agathosma bisulca	Others
BXGF03759	Stephania glabra	Stephania glabra	Medicinal Plant
BXGF03775	Brickellia dentata	Brickellia dentata	Others
BXGF03808	Hymenoxys ivesiana	Hymenoxys ivesiana	Others
BXGF03828	Phellodendron amurense	Phellodendron amurense	Medicinal Plant
BXGF04006	Corydalis ternata	Corydalis ternata	Others
BXGF04256	Phellodendron chinese	Phellodendron chinese	Others
BXGF04761	Corydalis tuberosa	Corydalis tuberosa	Medicinal Plant
BXGF04784	Coptis teeta	Coptis teeta	Medicinal Plant
BXGF04808	Dovyalis hebecarpa	Dovyalis hebecarpa	Human Edible Plant
BXGF04841	Lycopodium chinense	Lycopodium chinense	Others
BXGF04852	Ixeris repens	Ixeris repens	Medicinal Plant
BXGF04883	Eremophila oppositifolia	Eremophila oppositifolia	Others
BXGF04892	Achyrocline satureioides	Achyrocline satureioides	Medicinal Plant
BXGF04894	Taxillus yadoriki	Taxillus yadoriki	Others
BXGF04912	Corydalis rhizoma	Corydalis rhizoma	Others
BXGF05506	Coptis chinensis	Coptis chinensis	Medicinal Plant
BXGF05994	Corydalis yanhusuo	Corydalis yanhusuo	Medicinal Plant

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}