acompound

Showing entry for (Z)-3-(3,4-Dihydroxyphenyl)Prop-2-Enoic Acid

General Compound Information
BXGC Id	BXGC0013359
Compound Name	(Z)-3-(3,4-Dihydroxyphenyl)Prop-2-Enoic Acid
Structure
Formula	C9H8O4
InchiKey	QAIPRVGONGVQAS-RQOWECAXSA-N
SMILES	OC(=O)/C=C\c1ccc(c(c1)O)O
Inchi	InChI=1S/C9H8O4/c10-7-3-1-6(5-8(7)11)2-4-9(12)13/h1-5,10-11H,(H,12,13)/b4-2-
IUPAC	(Z)-3-(3,4-dihydroxyphenyl)prop-2-enoic acid
Molecular Weight	180.04
Pubchem Id	1549111
Chembl Id	CHEMBL1320034

Targets of Information Source

DrugBank

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type

PDB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1

Binding DB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM

CHEMBL

CHEMBL1320034

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
P16473	BXGT008234	Thyrotropin receptor	reviewed	G-protein coupled receptor	TSHR	Potency	'='	794	nM
B2RXH2	BXGT002006	Lysine-specific demethylase 4E	reviewed	-	KDM4E	Potency	'='	11220	nM
Q99714	BXGT019954	3-hydroxyacyl-CoA dehydrogenase type-2	reviewed	Enzyme	HSD17B10	Potency	'='	10000	nM
Q9F4F7	BXGT020344	4'-phosphopantetheinyl transferase ffp	reviewed	-	ffp	Potency	'='	35481	nM
Q16665	BXGT013653	Hypoxia-inducible factor 1-alpha	reviewed	Transcription factor	HIF1A	Potency	'='	7943	nM
P11712	BXGT007738	Cytochrome P450 2C9	reviewed	-	CYP2C9	AC50	'='	15848	nM
P11712	BXGT007738	Cytochrome P450 2C9	reviewed	-	CYP2C9	Potency	'='	15848	nM
Q96KQ7	BXGT019687	Histone-lysine N-methyltransferase EHMT2	reviewed	Epigenetic regulator	EHMT2	Potency	-	2511	nM
Q99714	BXGT019954	3-hydroxyacyl-CoA dehydrogenase type-2	reviewed	Enzyme	HSD17B10	Potency	'='	158	nM
P05177	BXGT006336	Cytochrome P450 1A2	reviewed	Enzyme	CYP1A2	AC50	-	-	-
P10635	BXGT007595	Cytochrome P450 2D6	reviewed	-	CYP2D6	AC50	-	-	-
Q99714	BXGT019954	3-hydroxyacyl-CoA dehydrogenase type-2	reviewed	Enzyme	HSD17B10	Potency	'='	1258	nM
P15917	BXGT008169	Lethal factor	reviewed	-	lef	Potency	'='	12589	nM
P16473	BXGT008234	Thyrotropin receptor	reviewed	G-protein coupled receptor	TSHR	Potency	'='	7943	nM
P08684	BXGT006812	Cytochrome P450 3A4	reviewed	Enzyme	CYP3A4	AC50	-	-	-
Q99714	BXGT019954	3-hydroxyacyl-CoA dehydrogenase type-2	reviewed	Enzyme	HSD17B10	Potency	'='	50	nM
P33261	BXGT009707	Cytochrome P450 2C19	reviewed	-	CYP2C19	AC50	-	-	-

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF00004	Kiwi	Actinidia chinensis	Fruits
BXGF00008	Garlic	Allium sativum	Herbs and Spices
BXGF00017	Burdock	Arctium lappa	Vegetables
BXGF00027	Chinese mustard	Brassica juncea	Vegetables
BXGF00042	Safflower	Carthamus tinctorius	Herbs and Spices
BXGF00046	Roman camomile	Chamaemelum nobile	Herbs and Spices
BXGF00049	Chicory	Cichorium intybus	Vegetables
BXGF00054	Lemon	Citrus limon	Fruits
BXGF00055	Pummelo	Citrus maxima	Fruits
BXGF00056	Mandarin orange (Clementine, Tangerine)	Citrus reticulata	Fruits
BXGF00063	Saffron	Crocus sativus	Herbs and Spices
BXGF00087	Sea-buckthornberry	Hippophae rhamnoides	Fruits
BXGF00101	Flaxseed	Linum usitatissimum	Herbs and Spices
BXGF00111	Cornmint	Mentha arvensis	Herbs and Spices
BXGF00118	Nutmeg	Myristica fragrans	Herbs and Spices
BXGF00142	Purslane	Portulaca oleracea	Herbs and Spices
BXGF00151	Pomegranate	Punica granatum	Fruits
BXGF00179	Cloves	Syzygium aromaticum	Herbs and Spices
BXGF00181	Dandelion	Taraxacum officinale	Herbs and Spices
BXGF00183	Common thyme	Thymus vulgaris	Herbs and Spices
BXGF00337	Ginkgo nuts	Ginkgo biloba	Herbs and Spices
BXGF00369	Sacred lotus	Nelumbo nucifera	Vegetables
BXGF00380	White mustard	Sinapis alba	Herbs and Spices
BXGF00402	Opium poppy	Papaver somniferum	Herbs and Spices
BXGF00871	Citrus unshiu	Citrus unshiu	Medicinal Plant
BXGF00872	Equisetum hyemale	Equisetum hyemale	Medicinal Plant
BXGF00886	Abutilon theophrasti	Abutilon theophrasti	Medicinal Plant
BXGF00910	Glechoma longituba	Glechoma longituba	Medicinal Plant
BXGF00948	Artemisia apiacea	Artemisia apiacea	Medicinal Plant
BXGF01009	Dipsacus asper	Dipsacus asper	Others
BXGF01031	Epimedium sagittatum	Epimedium sagittatum	Medicinal Plant
BXGF01065	Artemisia capillaris	Artemisia capillaris	Medicinal Plant
BXGF01074	Centella asiatica	Centella asiatica	Medicinal Plant
BXGF01126	Polygonum cuspidatum	Polygonum cuspidatum	Medicinal Plant
BXGF01140	Angelica gigas	Angelica gigas	Medicinal Plant
BXGF01147	Chelidonium majus	Chelidonium majus	Medicinal Plant
BXGF01185	Aloe vera	Aloe vera	Medicinal Plant
BXGF01230	Lithospermum erythrorhizon	Lithospermum erythrorhizon	Medicinal Plant
BXGF01260	Eleutherococcus senticosus	Eleutherococcus senticosus	Medicinal Plant
BXGF01283	Crataegus pinnatifida	Crataegus pinnatifida	Medicinal Plant
BXGF01315	Ipomoea purpurea	Ipomoea purpurea	Medicinal Plant
BXGF01325	Murraya exotica	Murraya exotica	Medicinal Plant
BXGF01341	Trachelospermum jasminoides	Trachelospermum jasminoides	Medicinal Plant
BXGF01391	Dodonaea viscosa	Dodonaea viscosa	Medicinal Plant
BXGF01423	Sauromatum giganteum	Sauromatum giganteum	Others
BXGF01426	Cornus officinalis	Cornus officinalis	Medicinal Plant
BXGF01506	Thymus quinquecostatus	Thymus quinquecostatus	Medicinal Plant
BXGF01530	Lophatherum gracile	Lophatherum gracile	Medicinal Plant
BXGF01609	Epimedium sempervirens	Epimedium sempervirens	Others
BXGF01668	Taraxacum platycarpum	Taraxacum platycarpum	Medicinal Plant
BXGF01716	Mentha canadensis	Mentha canadensis	Medicinal Plant
BXGF01743	Uncaria macrophylla	Uncaria macrophylla	Medicinal Plant
BXGF01767	Uncaria rhynchophylla	Uncaria rhynchophylla	Medicinal Plant
BXGF01780	Selaginella tamariscina	Selaginella tamariscina	Medicinal Plant
BXGF01868	Vitex negundo	Vitex negundo	Medicinal Plant
BXGF01896	Lilium brownii	Lilium brownii	Medicinal Plant
BXGF01900	Aloe ferox	Aloe ferox	Medicinal Plant
BXGF01910	Trachelospermum asiaticum	Trachelospermum asiaticum	Medicinal Plant
BXGF01973	Lonicera japonica	Lonicera japonica	Medicinal Plant
BXGF01987	Fraxinus chinensis	Fraxinus chinensis	Medicinal Plant
BXGF01991	Rosa rugosa	Rosa rugosa	Medicinal Plant
BXGF02024	Actaea dahurica	Actaea dahurica	Human Edible Plant
BXGF02049	Angelica sinensis	Angelica sinensis	Medicinal Plant
BXGF02143	Actaea cimicifuga	Actaea cimicifuga	Medicinal Plant
BXGF02152	Taraxacum borealisinense	Taraxacum borealisinense	Others
BXGF02204	Apocynum venetum	Apocynum venetum	Medicinal Plant
BXGF02359	Eucommia ulmoides	Eucommia ulmoides	Medicinal Plant
BXGF02361	Hypericum laricifolium	Hypericum laricifolium	Medicinal Plant
BXGF02370	Epimedium pubescens	Epimedium pubescens	Medicinal Plant
BXGF02377	Cichorium glandulosum	Cichorium glandulosum	Others
BXGF02388	Ipomoea nil	Ipomoea nil	Medicinal Plant
BXGF02393	Lonicera macranthoides	Lonicera macranthoides	Medicinal Plant
BXGF02444	Valeriana officinalis	Valeriana officinalis	Medicinal Plant
BXGF02481	Prunella vulgaris	Prunella vulgaris	Medicinal Plant
BXGF02509	Xanthium sibiricum	Xanthium sibiricum	Medicinal Plant
BXGF02542	Inula helenium	Inula helenium	Medicinal Plant
BXGF02551	Inula britannica	Inula britannica	Medicinal Plant
BXGF02567	Lycium chinense	Lycium chinense	Medicinal Plant
BXGF02612	Mosla chinensis	Mosla chinensis	Medicinal Plant
BXGF02620	Rosa chinensis	Rosa chinensis	Medicinal Plant
BXGF02731	Saussurea involucrata	Saussurea involucrata	Medicinal Plant
BXGF02786	Rubus coreanus	Rubus coreanus	Human Edible Plant
BXGF02787	Melia azedarach	Melia azedarach	Medicinal Plant
BXGF02792	Ligusticum sinense	Ligusticum sinense	Medicinal Plant
BXGF02881	Epimedium grandiflorum	Epimedium grandiflorum	Medicinal Plant
BXGF02937	Senecio scandens	Senecio scandens	Medicinal Plant
BXGF02956	Forsythia viridissima	Forsythia viridissima	Medicinal Plant
BXGF03023	Actinidia polygama	Actinidia polygama	Medicinal Plant
BXGF03078	Chrysanthemum x morifolium	Chrysanthemum x morifolium	Medicinal Plant
BXGF03110	Gleditsia sinensis	Gleditsia sinensis	Medicinal Plant
BXGF03158	Rheum officinale	Rheum officinale	Medicinal Plant
BXGF03189	Rhododendron dauricum	Rhododendron dauricum	Medicinal Plant
BXGF03240	Lonicera hypoglauca	Lonicera hypoglauca	Medicinal Plant
BXGF03243	Elsholtzia ciliata	Elsholtzia ciliata	Medicinal Plant
BXGF03253	Forsythia suspensa	Forsythia suspensa	Medicinal Plant
BXGF03255	Datura inoxia	Datura inoxia	Medicinal Plant
BXGF03341	Lycopus lucidus	Lycopus lucidus	Medicinal Plant
BXGF03379	Cnidium officinale	Cnidium officinale	Medicinal Plant
BXGF03398	Solanum nigrum	Solanum nigrum	Medicinal Plant
BXGF03432	Chrysanthemum indicum	Chrysanthemum indicum	Medicinal Plant
BXGF03576	Actinidia deliciosa	Actinidia deliciosa	Medicinal Plant
BXGF03580	Urtica dioica	Urtica dioica	Medicinal Plant
BXGF03583	Epimedium koreanum	Epimedium koreanum	Medicinal Plant
BXGF03602	Orobanche coerulescens	Orobanche coerulescens	Medicinal Plant
BXGF03630	Taraxacum coreanum	Taraxacum coreanum	Others
BXGF03645	Lycium barbarum	Lycium barbarum	Medicinal Plant
BXGF03710	Solidago decurrens	Solidago decurrens	Others
BXGF03765	Alcea rosea	Alcea rosea	Medicinal Plant
BXGF03766	Drynaria fortunei	Drynaria fortunei	Medicinal Plant
BXGF03769	Artemisia iwayomogi	Artemisia iwayomogi	Others
BXGF03889	Lonicera fulvotomentosa	Lonicera fulvotomentosa	Medicinal Plant
BXGF03891	Rhodiola sacra	Rhodiola sacra	Medicinal Plant
BXGF03895	Cibotium barometz	Cibotium barometz	Medicinal Plant
BXGF03908	Hedysarum multijugum maxim	Hedysarum multijugum maxim	Others
BXGF03919	Xanthium strumarium	Xanthium strumarium	Medicinal Plant
BXGF03933	Achillea millefolium	Achillea millefolium	Medicinal Plant
BXGF03960	Conium maculatum	Conium maculatum	Medicinal Plant
BXGF03988	Rheum coreanum	Rheum coreanum	Others
BXGF04053	Smilax china	Smilax china	Medicinal Plant
BXGF04122	Glechoma grandis	Glechoma grandis	Medicinal Plant
BXGF04200	Euphorbia hirta	Euphorbia hirta	Medicinal Plant
BXGF04209	Chaenomeles sinensis	Chaenomeles sinensis	Medicinal Plant
BXGF04211	Actinidia arguta	Actinidia arguta	Medicinal Plant
BXGF04235	Rubus chingii	Rubus chingii	Food Plant
BXGF04271	Artemisia annua	Artemisia annua	Medicinal Plant
BXGF04310	Taraxacum mongolicum	Taraxacum mongolicum	Medicinal Plant
BXGF04323	Orobanche pycnostachya	Orobanche pycnostachya	Others
BXGF04382	Murraya paniculata	Murraya paniculata	Medicinal Plant
BXGF04402	Actaea simplex	Actaea simplex	Others
BXGF04539	Rheum palmatum	Rheum palmatum	Medicinal Plant
BXGF04588	Valeriana jatamansii	Valeriana jatamansii	Medicinal Plant
BXGF04607	Morus alba	Morus alba	Medicinal Plant
BXGF04631	Aloe spicata	Aloe spicata	Medicinal Plant
BXGF04643	Selaginella pulvinata	Selaginella pulvinata	Medicinal Plant
BXGF04698	Isodon rubescens	Isodon rubescens	Others
BXGF04711	Cuscuta australis	Cuscuta australis	Medicinal Plant
BXGF04712	Prunus mume	Prunus mume	Medicinal Plant
BXGF04817	Euonymus alatus	Euonymus alatus	Medicinal Plant
BXGF04842	Angelica acutiloba	Angelica acutiloba	Medicinal Plant
BXGF04845	Sarcandra glabra	Sarcandra glabra	Medicinal Plant
BXGF04864	Uncaria sinensis	Uncaria sinensis	Medicinal Plant
BXGF04881	Fallopia multiflora	Fallopia multiflora	Medicinal Plant
BXGF04889	Pogostemon cablin	Pogostemon cablin	Medicinal Plant
BXGF04926	Aloe africana	Aloe africana	Medicinal Plant
BXGF04953	Polygonum aviculare	Polygonum aviculare	Medicinal Plant
BXGF05041	Desmodium styracifolium	Desmodium styracifolium	Medicinal Plant
BXGF05112	Fraxinus stylosa	Fraxinus stylosa	Medicinal Plant
BXGF05160	Chaenomeles speciosa	Chaenomeles speciosa	Medicinal Plant
BXGF05204	Erigeron breviscapus	Erigeron breviscapus	Medicinal Plant
BXGF05235	Phlomoides rotata	Phlomoides rotata	Others
BXGF05269	Hypericum perforatum	Hypericum perforatum	Medicinal Plant
BXGF05274	Lilium lancifolium	Lilium lancifolium	Medicinal Plant
BXGF05276	Digitalis purpurea	Digitalis purpurea	Medicinal Plant
BXGF05297	Isatis tinctoria	Isatis tinctoria	Medicinal Plant
BXGF05304	Lonicera confusa	Lonicera confusa	Medicinal Plant
BXGF05345	Phlomis umbrosa	Phlomis umbrosa	Medicinal Plant
BXGF05367	Toxicodendron vernicifluum	Toxicodendron vernicifluum	Medicinal Plant
BXGF05370	Epimedium brevicornu	Epimedium brevicornu	Others
BXGF05421	Tussilago farfara	Tussilago farfara	Medicinal Plant
BXGF05444	Aconitum koreanum	Aconitum koreanum	Medicinal Plant
BXGF05491	Harpagophytum procumbens	Harpagophytum procumbens	Medicinal Plant
BXGF05525	Phellodendron japonicum	Phellodendron japonicum	Medicinal Plant
BXGF05526	Salvia miltiorrhiza	Salvia miltiorrhiza	Medicinal Plant
BXGF05554	Hibiscus taiwanensis	Hibiscus taiwanensis	Medicinal Plant
BXGF05571	Ziziphus jujuba	Ziziphus jujuba	Medicinal Plant
BXGF05670	Scrophularia buergeriana	Scrophularia buergeriana	Medicinal Plant
BXGF05787	Smilax glabra	Smilax glabra	Medicinal Plant
BXGF05876	Gleditsia japonica	Gleditsia japonica	Medicinal Plant
BXGF05877	Rheum tanguticum	Rheum tanguticum	Medicinal Plant
BXGF05931	Lilium pumilum	Lilium pumilum	Medicinal Plant
BXGF05936	Commelina communis	Commelina communis	Medicinal Plant
BXGF06070	Perilla frutescens	Perilla frutescens	Medicinal Plant
BXGF06107	Glehnia littoralis	Glehnia littoralis	Medicinal Plant
BXGF06108	Centipeda minima	Centipeda minima	Medicinal Plant
BXGF06143	Persicaria tinctoria	Persicaria tinctoria	Medicinal Plant
BXGF06156	Inula japonica	Inula japonica	Medicinal Plant
BXGF06161	Epimedium wushanense	Epimedium wushanense	Medicinal Plant
BXGF06238	Gardenia jasminoides	Gardenia jasminoides	Medicinal Plant
BXGF06269	Fraxinus szaboana	Fraxinus szaboana	Medicinal Plant

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}