acompound

General Compound Information
BXGC Id	BXGC0015499
Compound Name	Euphorbiasteroid
Structure
Formula	C32H40O8
InchiKey	SDGDWRYYHQOQOJ-XXMLZKCSSA-N
SMILES	O=C(O[C@H]1[C@@H](C)C[C@]2([C@H]1[C@H](OC(=O)C)[C@@]1(CC[C@H]3[C@@H](/C=C(/C2=O)\C)C3(C)C)CO1)OC(=O)C)Cc1ccccc1
Inchi	InChI=1S/C32H40O8/c1-18-14-24-23(30(24,5)6)12-13-31(17-37-31)29(38-20(3)33)26-27(39-25(35)15-22-10-8-7-9-11-22)19(2)16-32(26,28(18)36)40-21(4)34/h7-11,14,19,23-24,26-27,29H,12-13,15-17H2,1-6H3/b18-14+/t19-,23-,24+,26+,27-,29-,31+,32+/m0/s1
IUPAC
Molecular Weight	552.27
Pubchem Id	15940183
Chembl Id	CHEMBL1437184

Targets of Information Source

DrugBank

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type

PDB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1

Binding DB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM

CHEMBL

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
Q9UBT6	BXGT021664	DNA polymerase kappa	reviewed	-	POLK	Potency	-	39810	nM
P25779	BXGT009067	Cruzipain	reviewed	-		Potency	'='	22387	nM
P10636	BXGT007596	Microtubule-associated protein tau	reviewed	-	MAPT	Potency	'='	19952	nM
P51450	BXGT010847	Nuclear receptor ROR-gamma	reviewed	-	Rorc	Potency	'='	15848	nM
P81908	BXGT011959	Cholinesterase	reviewed	-	BCHE	Inhibition	'='	-5	%
O42275	BXGT004559	Acetylcholinesterase	reviewed	-	ache	Inhibition	'='	-2	%

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF00849	Thymus transcaucasicus	Thymus transcaucasicus	Others
BXGF00860	Bruguiera cylindrica	Bruguiera cylindrica	Medicinal Plant
BXGF00988	Plantago uniflora	Plantago uniflora	Others
BXGF01027	Kalanchoe marmorata	Kalanchoe marmorata	Others
BXGF01265	Macaranga tanarius	Macaranga tanarius	Medicinal Plant
BXGF01306	Swartzia madagascariensis	Swartzia madagascariensis	Medicinal Plant
BXGF01978	Jacobaea adonidifolia	Jacobaea adonidifolia	Others
BXGF03860	Machilus robusta	Machilus robusta	Others
BXGF04950	Vitex pinnata	Vitex pinnata	Medicinal Plant
BXGF05092	Elaeocarpus fuscoides	Elaeocarpus fuscoides	Others
BXGF05243	Thymus magnus	Thymus magnus	Medicinal Plant
BXGF05284	Ecbolium linneanum	Ecbolium linneanum	Medicinal Plant
BXGF05416	Euphorbia lathyris	Euphorbia lathyris	Medicinal Plant
BXGF05447	Calodendrum capense	Calodendrum capense	Medicinal Plant
BXGF05479	Stevia purpurea	Stevia purpurea	Others
BXGF05493	Jacobaea arnautorum	Jacobaea arnautorum	Others
BXGF05624	Croton caudatus	Croton caudatus	Medicinal Plant
BXGF05781	Oxera splendida	Oxera splendida	Others
BXGF05996	Pseudophegopteris subaurita	Pseudophegopteris subaurita	Medicinal Plant
BXGF06046	Meconopsis horridula	Meconopsis horridula	Medicinal Plant
BXGF06303	Symphytum tuberosum	Symphytum tuberosum	Medicinal Plant

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}