acompound

Showing entry for Costatolide

　　　　　　　　　　　　　　　

General Compound Information
BXGC Id	BXGC0018173
Compound Name	Costatolide
Structure
Formula	C22H26O5
InchiKey	NIDRYBLTWYFCFV-PZROIBLQSA-N
SMILES	CCCc1cc(=O)oc2c1c1OC(C)(C)C=Cc1c1c2[C@@H](O)[C@H]([C@@H](O1)C)C
Inchi	InChI=1S/C22H26O5/c1-6-7-13-10-15(23)26-21-16(13)20-14(8-9-22(4,5)27-20)19-17(21)18(24)11(2)12(3)25-19/h8-12,18,24H,6-7H2,1-5H3/t11-,12-,18-/m0/s1
IUPAC
Molecular Weight	370.18
Pubchem Id	461128
Chembl Id	CHEMBL7187

Targets of Information Source

DrugBank

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type

PDB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1

Binding DB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM

CHEMBL

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
P0A8V2	BXGT007156	DNA-directed RNA polymerase subunit beta	reviewed	-	rpoB	IC50	-	-	-
Q72547	BXGT016709	Reverse transcriptase/RNaseH	unreviewed	-	pol	IC50	-	-	-
P0A8V2	BXGT007156	DNA-directed RNA polymerase subunit beta	reviewed	-	rpoB	Inhibition	'='	12	%
Q72874	BXGT016711	Pol polyprotein	unreviewed	-	pol	Inhibition	'='	68	%
Q72547	BXGT016709	Reverse transcriptase/RNaseH	unreviewed	-	pol	Inhibition	'='	5	%
Q72874	BXGT016711	Pol polyprotein	unreviewed	-	pol	Inhibition	'='	52	%
Q72874	BXGT016711	Pol polyprotein	unreviewed	-	pol	IC50	-	-	-
Q72874	BXGT016711	Pol polyprotein	unreviewed	-	pol	Inhibition	'='	0	%
Q72874	BXGT016711	Pol polyprotein	unreviewed	-	pol	IC50	'='	27800	nM
Q72874	BXGT016711	Pol polyprotein	unreviewed	-	pol	IC50	'='	155700	nM
Q9WKE8	BXGT021921	Reverse transcriptase	unreviewed	-	reverse	IC50	'='	290	nM
Q9WKE8	BXGT021921	Reverse transcriptase	unreviewed	-	reverse	IC50	'='	1400	nM

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF02462	Calophyllum lanigerum	Calophyllum lanigerum	Others

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}