acompound

Showing entry for Gf

　　　　　　　　　　　　　　　

General Compound Information
BXGC Id	BXGC0021265
Compound Name	Gf
Structure
Formula	C11H14N2O3
InchiKey	JBCLFWXMTIKCCB-VIFPVBQESA-N
SMILES	NCC(=N[C@H](C(=O)O)Cc1ccccc1)O
Inchi	InChI=1S/C11H14N2O3/c12-7-10(14)13-9(11(15)16)6-8-4-2-1-3-5-8/h1-5,9H,6-7,12H2,(H,13,14)(H,15,16)/t9-/m0/s1
IUPAC	(2S)-2-[(2-azaniumylacetyl)amino]-3-phenylpropanoate
Molecular Weight	222.1
Pubchem Id	92953
Chembl Id	CHEMBL299889

Targets of Information Source

DrugBank

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type

PDB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1

Binding DB

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
reviewed	BXGT007849	Angiotensin-converting enzyme	reviewed	Enzyme	ACE	-	2.75E+11	-	-
reviewed	BXGT010500	Solute carrier family 15 member 1	reviewed	Transporter	SLC15A1	-	-	-	130000
reviewed	BXGT010500	Solute carrier family 15 member 1	reviewed	Transporter	SLC15A1	-	170000	-	-
reviewed	BXGT007849	Angiotensin-converting enzyme	reviewed	Enzyme	ACE	-	602560	-	-
reviewed	BXGT007849	Angiotensin-converting enzyme	reviewed	Enzyme	ACE	-	630957.34	-	-

CHEMBL

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
P19145	BXGT008463	General amino-acid permease GAP1	reviewed	-	GAP1	Inhibition	'>='	30	%
P12821	BXGT007849	Angiotensin-converting enzyme	reviewed	Enzyme	ACE	IC50	'='	630957	nM
P19145	BXGT008463	General amino-acid permease GAP1	reviewed	-	GAP1	Activity	'<'	15	%
P46059	BXGT010500	Solute carrier family 15 member 1	reviewed	Transporter	SLC15A1	EC50	'='	130000	nM
Q63424	BXGT016071	Solute carrier family 15 member 2	reviewed	-	Slc15a2	Ki	'='	8000	nM
P12821	BXGT007849	Angiotensin-converting enzyme	reviewed	Enzyme	ACE	IC50	'='	602559	nM
P46059	BXGT010500	Solute carrier family 15 member 1	reviewed	Transporter	SLC15A1	IC50	'='	170000	nM
Q64560	BXGT016125	Tripeptidyl-peptidase 2	reviewed	-	Tpp2	Ki	'='	470000	nM
P46059	BXGT010500	Solute carrier family 15 member 1	reviewed	Transporter	SLC15A1	Ratio	'='	830	-
P46059	BXGT010500	Solute carrier family 15 member 1	reviewed	Transporter	SLC15A1	max activation	'='	111	%
P51574	BXGT010860	Solute carrier family 15 member 1	reviewed	-	Slc15a1	Ki	'='	170000	nM
Q63424	BXGT016071	Solute carrier family 15 member 2	reviewed	-	Slc15a2	Activity	-	-	-
P12821	BXGT007849	Angiotensin-converting enzyme	reviewed	Enzyme	ACE	logIC50	'='	2	-
Q16348	BXGT013627	Solute carrier family 15 member 2	reviewed	Transporter	SLC15A2	Activity	'='	0	%

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF03363	Hypericum japonicum	Hypericum japonicum	Medicinal Plant

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}