Showing entry for 3-hydroxypyridine


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0022674
Compound Name3-hydroxypyridine
Structure
FormulaC5H5NO
InchiKeyGRFNBEZIAWKNCO-UHFFFAOYSA-N
SMILESOc1cccnc1
InchiInChI=1S/C5H5NO/c7-5-2-1-3-6-4-5/h1-4,7H
IUPACpyridin-3-ol
Molecular Weight95.04
Pubchem Id7971
Chembl IdCHEMBL237847
Targets of Information Source
DrugBank n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
PDB 71A
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform reviewed PIK3CA Kinase - - - -
Binding DB 50225189
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
reviewed BXGT006812 Cytochrome P450 3A4 reviewed Enzyme CYP3A4 - 767400 - -
CHEMBL CHEMBL237847
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
P08684 BXGT006812 Cytochrome P450 3A4 reviewed Enzyme CYP3A4 IC50 '=' 767361 nM
P0A0J7 BXGT006970 Quinolone resistance protein NorA reviewed - norA Activity '>' 128 ug ml-1
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform reviewed Kinase PIK3CA Inhibition '<' 25 %
P27986 BXGT009216 Phosphatidylinositol 3-kinase regulatory subunit alpha reviewed Kinase PIK3R1 Inhibition '<' 25 %
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform reviewed Kinase PIK3CA Inhibition '<' 25 %
O42275 BXGT004559 Acetylcholinesterase reviewed - ache Activity - - -
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF00040 Pepper (C. annuum) Capsicum annuum Vegetables
BXGF04909 Hippophae fructus Hippophae fructus Others
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease