acompound

Showing entry for 4,4'-Dihydroxychalcone

　　　　　　　　　　　　　　　

General Compound Information
BXGC Id	BXGC0022789
Compound Name	4,4'-Dihydroxychalcone
Structure
Formula	C15H12O3
InchiKey	FZQLEXXZAVVCCA-XCVCLJGOSA-N
SMILES	Oc1ccc(cc1)/C=C/C(=O)c1ccc(cc1)O
Inchi	InChI=1S/C15H12O3/c16-13-6-1-11(2-7-13)3-10-15(18)12-4-8-14(17)9-5-12/h1-10,16-17H/b10-3+
IUPAC	(E)-1,3-bis(4-hydroxyphenyl)prop-2-en-1-one
Molecular Weight	240.08
Pubchem Id	5467477
Chembl Id	CHEMBL145927

Targets of Information Source

DrugBank

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type

PDB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1

Binding DB

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
reviewed	BXGT004563	Polyphenol oxidase 2	reviewed		PPO2	-	4800	-	-
reviewed	BXGT004563	Polyphenol oxidase 2	reviewed		PPO2	2900	-	-	-

CHEMBL

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
O42713	BXGT004563	Polyphenol oxidase 2	reviewed	-	PPO2	IC50	'='	4800	nM
P06278	BXGT006431	Alpha-amylase	reviewed	-	amyS	Activity	-	-	-
P16098	BXGT008191	Beta-amylase	reviewed	-	BMY1	Activity	-	-	-
O42713	BXGT004563	Polyphenol oxidase 2	reviewed	-	PPO2	Ki	'='	2900	nM
P13726	BXGT007950	Tissue factor	reviewed	Receptor	F3	IC50	'='	0	nM
P80457	BXGT011911	Xanthine dehydrogenase/oxidase	reviewed	-	XDH	IC50	'='	117000	nM

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF05730	Alpinia blepharocalyx	Alpinia blepharocalyx	Medicinal Plant

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}