Showing entry for (S)-2-Aminoadipic Acid


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0023948
Compound Name(S)-2-Aminoadipic Acid
Structure
FormulaC6H11NO4
InchiKeyOYIFNHCXNCRBQI-BYPYZUCNSA-N
SMILESOC(=O)CCC[C@@H](C(=O)O)N
InchiInChI=1S/C6H11NO4/c7-4(6(10)11)2-1-3-5(8)9/h4H,1-3,7H2,(H,8,9)(H,10,11)/t4-/m0/s1
IUPAC(2S)-2-azaniumyl-6-hydroxy-6-oxohexanoate
Molecular Weight161.07
Pubchem Id92136
Chembl IdCHEMBL88804
Targets of Information Source
DrugBank n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
PDB UN1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Q5SH22 BXGT015667 Alpha-aminoadipate carrier protein LysW reviewed lysW - - - - -
P49419 BXGT010705 Alpha-aminoadipic semialdehyde dehydrogenase reviewed ALDH7A1 Enzyme - - - -
Q9ZND7 BXGT022472 Alpha-aminoadipate carrier protein LysW unreviewed orfF - - - - -
Q5JFV9 BXGT015440 Probable lysine biosynthesis protein unreviewed TK0279 - - - - -
Q5JFW0 BXGT015441 RimK-related lysine biosynthesis protein unreviewed TK0278 - - - - -
A0A1D8PMC5 BXGT024202 Aromatic-amino-acid:2-oxoglutarate transaminase unreviewed ARO9 - - - - -
O85725 BXGT025482 Semialdehyde dehydrogenase Pcd unreviewed pcd - - - - -
Binding DB 50052553
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
reviewed BXGT009542 Metabotropic glutamate receptor 5 reviewed Grm5 - - - >1000000
reviewed BXGT013468 Metabotropic glutamate receptor 2 reviewed G-protein coupled receptor GRM2 - - - 35000
reviewed BXGT009541 Metabotropic glutamate receptor 4 reviewed Grm4 - - - >3000000
reviewed BXGT008861 Metabotropic glutamate receptor 1 reviewed Grm1 - - - >1000000
reviewed BXGT013508 Metabotropic glutamate receptor 4 reviewed G-protein coupled receptor GRM4 - - - >3000000
reviewed BXGT004150 Metabotropic glutamate receptor 6 reviewed G-protein coupled receptor GRM6 - - - 140000
reviewed BXGT013332 Metabotropic glutamate receptor 1 reviewed G-protein coupled receptor GRM1 - - - >1000000
reviewed BXGT009815 Metabotropic glutamate receptor 6 reviewed Grm6 - - - 140000
reviewed BXGT010266 Metabotropic glutamate receptor 5 reviewed G-protein coupled receptor GRM5 >1000000 - - -
reviewed BXGT004150 Metabotropic glutamate receptor 6 reviewed G-protein coupled receptor GRM6 140000 - - -
reviewed BXGT013332 Metabotropic glutamate receptor 1 reviewed G-protein coupled receptor GRM1 >1000000 - - -
reviewed BXGT013508 Metabotropic glutamate receptor 4 reviewed G-protein coupled receptor GRM4 >3000000 - - -
reviewed BXGT013468 Metabotropic glutamate receptor 2 reviewed G-protein coupled receptor GRM2 35000 - - -
CHEMBL CHEMBL88804
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
P31423 BXGT009541 Metabotropic glutamate receptor 4 reviewed - Grm4 EC50 '>' 3000000 nM
P31421 BXGT009539 Metabotropic glutamate receptor 2 reviewed - Grm2 EC50 '=' 35000 nM
O15648 BXGT004185 ATP-dependent 6-phosphofructokinase reviewed - pfk Potency - 849 nM
Q13951 BXGT013407 Core-binding factor subunit beta reviewed - CBFB Potency - 8912 nM
Q01196 BXGT012575 Runt-related transcription factor 1 reviewed Transcription factor RUNX1 Potency - 8912 nM
Q13255 BXGT013332 Metabotropic glutamate receptor 1 reviewed G-protein coupled receptor GRM1 EC50 '>' 1000000 nM
P31424 BXGT009542 Metabotropic glutamate receptor 5 reviewed - Grm5 EC50 '>' 1000000 nM
P41594 BXGT010266 Metabotropic glutamate receptor 5 reviewed G-protein coupled receptor GRM5 Ki '>' 1000000 nM
P25779 BXGT009067 Cruzipain reviewed - Potency '=' 3162 nM
Q13255 BXGT013332 Metabotropic glutamate receptor 1 reviewed G-protein coupled receptor GRM1 Ki '>' 1000000 nM
Q96KQ7 BXGT019687 Histone-lysine N-methyltransferase EHMT2 reviewed Epigenetic regulator EHMT2 Potency - 70794 nM
Q14833 BXGT013508 Metabotropic glutamate receptor 4 reviewed G-protein coupled receptor GRM4 EC50 '>' 3000000 nM
O15303 BXGT004150 Metabotropic glutamate receptor 6 reviewed G-protein coupled receptor GRM6 EC50 '=' 140000 nM
P23385 BXGT008861 Metabotropic glutamate receptor 1 reviewed - Grm1 EC50 '>' 1000000 nM
Q14416 BXGT013468 Metabotropic glutamate receptor 2 reviewed G-protein coupled receptor GRM2 Ki '=' 35000 nM
O15303 BXGT004150 Metabotropic glutamate receptor 6 reviewed G-protein coupled receptor GRM6 Ki '=' 140000 nM
Q14416 BXGT013468 Metabotropic glutamate receptor 2 reviewed G-protein coupled receptor GRM2 EC50 '=' 35000 nM
O89049 BXGT005293 Thioredoxin reductase 1, cytoplasmic reviewed - Txnrd1 Potency - 100 nM
Q14833 BXGT013508 Metabotropic glutamate receptor 4 reviewed G-protein coupled receptor GRM4 Ki '>' 3000000 nM
P35349 BXGT009815 Metabotropic glutamate receptor 6 reviewed - Grm6 EC50 '=' 140000 nM
Q96KQ7 BXGT019687 Histone-lysine N-methyltransferase EHMT2 reviewed Epigenetic regulator EHMT2 Potency - 26679 nM
P54132 BXGT011032 Bloom syndrome protein reviewed - BLM Potency '=' 15 nM
P21728 BXGT008686 D(1A) dopamine receptor reviewed G-protein coupled receptor DRD1 Potency - 29 nM
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF00264 Alfalfa Medicago sativa Herbs and Spices
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease