acompound

Showing entry for dihydroartemisinin

　　　　　　　　　　　　　　　

General Compound Information
BXGC Id	BXGC0027583
Compound Name	dihydroartemisinin
Structure
Formula	C15H24O5
InchiKey	BJDCWCLMFKKGEE-UHFFFAOYSA-N
SMILES	OC1OC2OC3(C)CCC4C2(C(C1C)CCC4C)OO3
Inchi	InChI=1S/C15H24O5/c1-8-4-5-11-9(2)12(16)17-13-15(11)10(8)6-7-14(3,18-13)19-20-15/h8-13,16H,4-7H2,1-3H3
IUPAC
Molecular Weight	284.16
Pubchem Id	540327
Chembl Id	CHEMBL600715

Targets of Information Source

DrugBank

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type

PDB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1

Binding DB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM

CHEMBL

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
P25094	BXGT009014	Peripheral myelin protein 22	reviewed	-	Pmp22	Potency	-	1018	nM
Q16637	BXGT013646	Survival motor neuron protein	reviewed	Epigenetic regulator	SMN1	Potency	'='	7943	nM
P00352	BXGT005510	Retinal dehydrogenase 1	reviewed	Enzyme	ALDH1A1	Potency	'='	44668	nM
P04637	BXGT006243	Cellular tumor antigen p53	reviewed	Transcription factor	TP53	Potency	'='	25118	nM
P08684	BXGT006812	Cytochrome P450 3A4	reviewed	Enzyme	CYP3A4	Potency	'='	12589	nM
P02545	BXGT005889	Prelamin-A/C	reviewed	-	LMNA	Potency	'='	10000	nM
P42858	BXGT010341	Huntingtin	reviewed	-	HTT	Potency	'='	1995	nM
O75496	BXGT005132	Geminin	reviewed	-	GMNN	Potency	-	33498	nM
P11021	BXGT007644	Endoplasmic reticulum chaperone BiP	reviewed	-	HSPA5	Potency	-	50118	nM

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF00948	Artemisia apiacea	Artemisia apiacea	Medicinal Plant
BXGF04271	Artemisia annua	Artemisia annua	Medicinal Plant

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}