acompound

Showing entry for Disogenin

General Compound Information
BXGC Id	BXGC0032207
Compound Name	Disogenin
Structure
Formula	C27H42O3
InchiKey	WQLVFSAGQJTQCK-VKROHFNGSA-N
SMILES	C[C@@H]1CC[C@@]2(OC1)O[C@@H]1[C@H]([C@@H]2C)[C@@]2([C@@H](C1)[C@@H]1CC=C3[C@]([C@H]1CC2)(C)CC[C@@H](C3)O)C
Inchi	InChI=1S/C27H42O3/c1-16-7-12-27(29-15-16)17(2)24-23(30-27)14-22-20-6-5-18-13-19(28)8-10-25(18,3)21(20)9-11-26(22,24)4/h5,16-17,19-24,28H,6-15H2,1-4H3/t16-,17+,19+,20-,21+,22+,23+,24+,25+,26+,27-/m1/s1
IUPAC
Molecular Weight	414.31
Pubchem Id	99474
Chembl Id	CHEMBL412437

Targets of Information Source

DrugBank

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type

PDB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1

Binding DB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM

CHEMBL

CHEMBL412437

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
P22310	BXGT008754	UDP-glucuronosyltransferase 1-4	reviewed	-	UGT1A4	Km	'='	13000	nM
P35503	BXGT009840	UDP-glucuronosyltransferase 1-3	reviewed	-	UGT1A3	Activity	'='	0	pm/min/mg
P40763	BXGT010202	Signal transducer and activator of transcription 3	reviewed	Nucleic acid binding	STAT3	Inhibition	-	-	-
P22309	BXGT008753	UDP-glucuronosyltransferase 1-1	reviewed	-	UGT1A1	Activity	'='	0	pm/min/mg
Q9NPD5	BXGT021151	Solute carrier organic anion transporter family member 1B3	reviewed	Transporter	SLCO1B3	Inhibition	'='	85	%
Q9Y6L6	BXGT022334	Solute carrier organic anion transporter family member 1B1	reviewed	Transporter	SLCO1B1	Inhibition	'='	85	%
P22310	BXGT008754	UDP-glucuronosyltransferase 1-4	reviewed	-	UGT1A4	Activity	'='	173	pm/min/mg
Q9HAW9	BXGT020510	UDP-glucuronosyltransferase 1-8	reviewed	-	UGT1A8	Activity	'='	0	pm/min/mg
P40763	BXGT010202	Signal transducer and activator of transcription 3	reviewed	Nucleic acid binding	STAT3	Activity	-	-	-

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF00178	Spinach	Spinacia oleracea	Vegetables
BXGF00186	Fenugreek	Trigonella foenum-graecum	Herbs and Spices
BXGF00879	Anemone raddeana	Anemone raddeana	Others
BXGF00941	Clerodendrum infortunatum	Clerodendrum infortunatum	Medicinal Plant
BXGF01045	Dioscorea japonica	Dioscorea japonica	Medicinal Plant
BXGF01209	Solanum virginianum	Solanum virginianum	Medicinal Plant
BXGF01312	Aconitum forrestii	Aconitum forrestii	Others
BXGF01453	Phragmites australis	Phragmites australis	Medicinal Plant
BXGF01500	Sarcococca hookeriana	Sarcococca hookeriana	Others
BXGF01618	Adenium obesum	Adenium obesum	Medicinal Plant
BXGF01719	Ranunculus bulbosus	Ranunculus bulbosus	Medicinal Plant
BXGF01762	Persea kusanoi	Persea kusanoi	Others
BXGF01805	Borassus flabellifer	Borassus flabellifer	Medicinal Plant
BXGF01835	Dioscorea nipponica	Dioscorea nipponica	Medicinal Plant
BXGF01909	Calocedrus macrolepis	Calocedrus macrolepis	Others
BXGF01982	Salvia horminum	Salvia horminum	Others
BXGF02049	Angelica sinensis	Angelica sinensis	Medicinal Plant
BXGF02141	Microlepia marginata	Microlepia marginata	Others
BXGF02205	Neoboutonia glabrescens	Neoboutonia glabrescens	Others
BXGF02288	Canarium muelleri	Canarium muelleri	Human Edible Plant
BXGF02291	Primula denticulata	Primula denticulata	Medicinal Plant
BXGF02321	Campanula pendula	Campanula pendula	Others
BXGF02459	Asperula odorata	Asperula odorata	Medicinal Plant
BXGF02462	Calophyllum lanigerum	Calophyllum lanigerum	Others
BXGF02485	Gentiana bellidifolia	Gentiana bellidifolia	Others
BXGF02512	Rabdosia excisa	Rabdosia excisa	Medicinal Plant
BXGF02519	Dioscorea septemloba	Dioscorea septemloba	Others
BXGF02525	Sansevieria ehrenbergii	Sansevieria ehrenbergii	Human Edible Plant
BXGF02556	Parkia javanica	Parkia javanica	Medicinal Plant
BXGF02615	Lycopodium paniculatum	Lycopodium paniculatum	Others
BXGF02630	Euphorbia cattimandoo	Euphorbia cattimandoo	Others
BXGF02648	Mikania oblongifolia	Mikania oblongifolia	Others
BXGF02671	Mollugo cerviana	Mollugo cerviana	Human Edible Plant
BXGF02685	Capsicum baccatum	Capsicum baccatum	Medicinal Plant
BXGF02709	Berkheya radula	Berkheya radula	Others
BXGF02720	Fagopyrum cymosum	Fagopyrum cymosum	Medicinal Plant
BXGF02738	Piper puberulum	Piper puberulum	Others
BXGF02752	Paullinia pinnata	Paullinia pinnata	Medicinal Plant
BXGF02790	Selinum papyraceum	Selinum papyraceum	Others
BXGF02856	Garcinia latissima	Garcinia latissima	Others
BXGF02866	Albizia schimperana	Albizia schimperana	Others
BXGF02878	Podocarpus blumei	Podocarpus blumei	Others
BXGF02888	Daphniphyllum subverticillatum	Daphniphyllum subverticillatum	Others
BXGF02911	Marchantia polymorpha	Marchantia polymorpha	Others
BXGF02951	Arum montanum	Arum montanum	Others
BXGF02961	Sideritis condensata	Sideritis condensata	Human Edible Plant
BXGF03153	Lygodium pinnatifidum	Lygodium pinnatifidum	Others
BXGF03444	Gastrodia elata	Gastrodia elata	Medicinal Plant
BXGF03500	Croton megistocarpus	Croton megistocarpus	Others
BXGF03523	Solanum melongena l	Solanum melongena l	Others
BXGF03551	Buxus rolfei	Buxus rolfei	Others
BXGF03638	Turnera ulmifolia	Turnera ulmifolia	Medicinal Plant
BXGF03768	Teucrium cossonii	Teucrium cossonii	Others
BXGF03898	Dioscorea polystachya	Dioscorea polystachya	Medicinal Plant
BXGF04053	Smilax china	Smilax china	Medicinal Plant
BXGF04303	Anemarrhena asphodeloides	Anemarrhena asphodeloides	Medicinal Plant
BXGF04396	Dysosma pleiantha	Dysosma pleiantha	Others
BXGF04426	Daiswa polyphylla	Daiswa polyphylla	Medicinal Plant
BXGF04532	Solanum nigrum linn	Solanum nigrum linn	Others
BXGF04938	Achillea pratensis	Achillea pratensis	Others
BXGF05025	solanum violaceum	solanum violaceum	Medicinal Plant
BXGF05093	Eucalyptus campanulata	Eucalyptus campanulata	Others
BXGF05107	Cinnamomum pedunculatum	Cinnamomum pedunculatum	Others
BXGF05177	Alcea nudiflora	Alcea nudiflora	Others
BXGF05211	Boronia lanceolata	Boronia lanceolata	Others
BXGF05221	Corydalis crystallina	Corydalis crystallina	Others
BXGF05236	Ochradenus baccatus	Ochradenus baccatus	Human Edible Plant
BXGF05258	Geranium sibiricum	Geranium sibiricum	Medicinal Plant
BXGF05262	Chlorella pyrenoidosa	Chlorella pyrenoidosa	Others
BXGF05273	Plantago ovata	Plantago ovata	Medicinal Plant
BXGF05301	Baphicacanthus cusia	Baphicacanthus cusia	Medicinal Plant
BXGF05303	Lagerstroemia indica	Lagerstroemia indica	Medicinal Plant
BXGF05347	Lasianthus wallichii	Lasianthus wallichii	Others
BXGF05411	Mercurialis leiocarpa	Mercurialis leiocarpa	Others
BXGF05484	Thuja dolabrata	Thuja dolabrata	Others
BXGF05523	Rubus foliolosus	Rubus foliolosus	Human Edible Plant
BXGF05546	Lomandra hastilis	Lomandra hastilis	Others
BXGF05588	Acacia lemmoni	Acacia lemmoni	Others
BXGF05628	Podocarpus sellowii	Podocarpus sellowii	Others
BXGF05646	Neolitsea sericea	Neolitsea sericea	Medicinal Plant
BXGF05706	Anaphalis margaritacea	Anaphalis margaritacea	Medicinal Plant
BXGF05787	Smilax glabra	Smilax glabra	Medicinal Plant
BXGF05794	Capparis angulata	Capparis angulata	Others
BXGF05832	Hemiphragma heterophyllum	Hemiphragma heterophyllum	Medicinal Plant
BXGF05878	Senecio isatideus	Senecio isatideus	Others
BXGF05879	Klaseopsis chinensis	Klaseopsis chinensis	Others
BXGF05919	Dioscorea opposita	Dioscorea opposita	Human Edible Plant
BXGF05941	Chloranthus holostegius	Chloranthus holostegius	Others
BXGF06086	Euphorbia wallichii	Euphorbia wallichii	Others
BXGF06153	Carissa spinarum	Carissa spinarum	Medicinal Plant

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}