acompound

General Compound Information
BXGC Id	BXGC0033451
Compound Name	Caftaric Acid
Structure
Formula	C13H12O9
InchiKey	SWGKAHCIOQPKFW-JTNORFRNSA-N
SMILES	O=C(O[C@H]([C@H](C(=O)O)O)C(=O)O)/C=C/c1ccc(c(c1)O)O
Inchi	InChI=1S/C13H12O9/c14-7-3-1-6(5-8(7)15)2-4-9(16)22-11(13(20)21)10(17)12(18)19/h1-5,10-11,14-15,17H,(H,18,19)(H,20,21)/b4-2+/t10-,11-/m1/s1
IUPAC	(2R,3R)-2-[(E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy-3-hydroxybutanedioic acid
Molecular Weight	312.05
Pubchem Id	6440397
Chembl Id	CHEMBL558557

Targets of Information Source

DrugBank

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type

PDB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1

Binding DB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM

CHEMBL

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
P12931	BXGT007859	Proto-oncogene tyrosine-protein kinase Src	reviewed	Kinase	SRC	FC	'='	2	-
P42224	BXGT010286	Signal transducer and activator of transcription 1-alpha/beta	reviewed	Nucleic acid binding	STAT1	Inhibition	'='	19	%
P06239	BXGT006427	Tyrosine-protein kinase Lck	reviewed	Kinase	LCK	FC	'='	2	-
P40763	BXGT010202	Signal transducer and activator of transcription 3	reviewed	Nucleic acid binding	STAT3	Inhibition	'='	30	%
P51692	BXGT010885	Signal transducer and activator of transcription 5B	reviewed	Nucleic acid binding	STAT5B	Inhibition	'='	31	%
P12931	BXGT007859	Proto-oncogene tyrosine-protein kinase Src	reviewed	Kinase	SRC	IC50	'='	74000	nM
P06239	BXGT006427	Tyrosine-protein kinase Lck	reviewed	Kinase	LCK	IC50	'='	118000	nM

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF00049	Chicory	Cichorium intybus	Vegetables
BXGF00125	Rice	Oryza sativa	Cereals and cereal products
BXGF00181	Dandelion	Taraxacum officinale	Herbs and Spices
BXGF00868	Clusia torresii	Clusia torresii	Others
BXGF01037	Ferula assa-foetida	Ferula assa-foetida	Medicinal Plant
BXGF01094	Asplenium nidus	Asplenium nidus	Human Edible Plant
BXGF01668	Taraxacum platycarpum	Taraxacum platycarpum	Medicinal Plant
BXGF01758	Cirsium helenioides	Cirsium helenioides	Others
BXGF01904	Orthosiphon aristatus	Orthosiphon aristatus	Medicinal Plant
BXGF01924	Handroanthus guayacan	Handroanthus guayacan	Others
BXGF02152	Taraxacum borealisinense	Taraxacum borealisinense	Others
BXGF02249	Ulmus laciniata	Ulmus laciniata	Medicinal Plant
BXGF02377	Cichorium glandulosum	Cichorium glandulosum	Others
BXGF03630	Taraxacum coreanum	Taraxacum coreanum	Others
BXGF03928	Celmisia petriei	Celmisia petriei	Others
BXGF04310	Taraxacum mongolicum	Taraxacum mongolicum	Medicinal Plant
BXGF04698	Isodon rubescens	Isodon rubescens	Others
BXGF04844	Primula veris	Primula veris	Medicinal Plant
BXGF05481	Populus tremula	Populus tremula	Medicinal Plant
BXGF05553	Astragalus inopinatus	Astragalus inopinatus	Others
BXGF06125	Senecio integerrimus	Senecio integerrimus	Others

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}