acompound

Showing entry for (Z)-2-(3,4-Dihydroxybenzylidene)-6,7-Dihydroxybenzofuran-3(2H)-One

　　　　　　　　　　　　　　　

General Compound Information
BXGC Id	BXGC0034725
Compound Name	(Z)-2-(3,4-Dihydroxybenzylidene)-6,7-Dihydroxybenzofuran-3(2H)-One
Structure
Formula	C15H10O6
InchiKey	PNIFOHGQPKXLJE-SDQBBNPISA-N
SMILES	O=C1/C(=C/c2ccc(c(c2)O)O)/Oc2c1ccc(c2O)O
Inchi	InChI=1S/C15H10O6/c16-9-3-1-7(5-11(9)18)6-12-13(19)8-2-4-10(17)14(20)15(8)21-12/h1-6,16-18,20H/b12-6-
IUPAC	(2Z)-2-[(3,4-dihydroxyphenyl)methylidene]-6,7-dihydroxy-1-benzofuran-3-one
Molecular Weight	286.05
Pubchem Id	5281292
Chembl Id	CHEMBL3298066

Targets of Information Source

DrugBank

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type

PDB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1

Binding DB

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
reviewed	BXGT006306	Amyloid-beta precursor protein	reviewed	Enzyme modulator	APP	-	2700	-	-

CHEMBL

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
P05067	BXGT006306	Amyloid-beta precursor protein	reviewed	Enzyme modulator	APP	Activity	'='	18	%
P05067	BXGT006306	Amyloid-beta precursor protein	reviewed	Enzyme modulator	APP	IC50	'='	2700	nM
P05067	BXGT006306	Amyloid-beta precursor protein	reviewed	Enzyme modulator	APP	Inhibition	-	-	-

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF02311	Cirsium chinense	Cirsium chinense	Medicinal Plant
BXGF04244	Coreopsis tinctoria	Coreopsis tinctoria	Medicinal Plant

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}