Showing entry for Piceatannol


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0042870
Compound NamePiceatannol
Structure
FormulaC14H12O4
InchiKeyCDRPUGZCRXZLFL-OWOJBTEDSA-N
SMILESOc1cc(/C=C/c2ccc(c(c2)O)O)cc(c1)O
InchiInChI=1S/C14H12O4/c15-11-5-10(6-12(16)8-11)2-1-9-3-4-13(17)14(18)7-9/h1-8,15-18H/b2-1+
IUPAC4-[(E)-2-(3,5-dihydroxyphenyl)ethenyl]benzene-1,2-diol
Molecular Weight244.07
Pubchem Id667639
Chembl IdCHEMBL69863
Targets of Information Source
DrugBank DB08399
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
P25705 BXGT009060 ATP synthase subunit alpha, mitochondrial reviewed Transporter ATP5F1A experimental -
P06576 BXGT006454 ATP synthase subunit beta, mitochondrial reviewed Transporter ATP5F1B experimental -
P36542 BXGT009925 ATP synthase subunit gamma, mitochondrial reviewed Transporter ATP5F1C experimental -
PDB PIT
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
P05631 BXGT006372 ATP synthase subunit gamma, mitochondrial reviewed ATP5F1C - - - - -
Q9NTG7 BXGT021211 NAD-dependent protein deacetylase sirtuin-3, mitochondrial reviewed SIRT3 Epigenetic regulator - - - -
Q7S860 BXGT017096 Carotenoid oxygenase 1 unreviewed cao-1 - - - - -
Binding DB 50045936
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
reviewed BXGT020189 Serine/threonine-protein kinase 33 reviewed Kinase STK33 - - - 12790
reviewed BXGT007302 Endoribonuclease toxin MazF reviewed mazF - - - >99000
reviewed BXGT006427 Tyrosine-protein kinase Lck reviewed Kinase LCK - 66000 - -
reviewed BXGT006427 Tyrosine-protein kinase Lck reviewed Kinase LCK - 5000 - -
reviewed BXGT013591 Myosin light chain kinase, smooth muscle reviewed Kinase MYLK - 12000 - -
reviewed BXGT006427 Tyrosine-protein kinase Lck reviewed Kinase LCK - 20 - -
reviewed BXGT006427 Tyrosine-protein kinase Lck reviewed Kinase LCK - 82000 - -
reviewed BXGT010386 Tyrosine-protein kinase SYK reviewed Kinase SYK - 38000 - -
reviewed BXGT009301 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 reviewed Enzyme CD38 - >100000 - -
reviewed BXGT010386 Tyrosine-protein kinase SYK reviewed Kinase SYK - 10000 - -
reviewed BXGT010386 Tyrosine-protein kinase SYK reviewed Kinase SYK - - - 25000
reviewed BXGT010386 Tyrosine-protein kinase SYK reviewed Kinase SYK - - - 5000
CHEMBL CHEMBL69863
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
Q9UBT6 BXGT021664 DNA polymerase kappa reviewed - POLK Potency - 2818 nM
P83916 BXGT012025 Chromobox protein homolog 1 reviewed Epigenetic regulator CBX1 Potency - 44668 nM
P00352 BXGT005510 Retinal dehydrogenase 1 reviewed Enzyme ALDH1A1 Potency '=' 10000 nM
P10636 BXGT007596 Microtubule-associated protein tau reviewed - MAPT Potency '=' 8912 nM
Q962Y6 BXGT019597 Thioredoxin glutathione reductase unreviewed - TGR Potency '=' 22387 nM
Q8IXJ6 BXGT018362 NAD-dependent protein deacetylase sirtuin-2 reviewed Epigenetic regulator SIRT2 Inhibition '>' 60 %
Q13951 BXGT013407 Core-binding factor subunit beta reviewed - CBFB Potency - 15848 nM
Q01196 BXGT012575 Runt-related transcription factor 1 reviewed Transcription factor RUNX1 Potency - 15848 nM
P38398 BXGT010037 Breast cancer type 1 susceptibility protein reviewed Enzyme BRCA1 Potency - 17782 nM
Q9UBT6 BXGT021664 DNA polymerase kappa reviewed - POLK Potency - 21192 nM
P42345 BXGT010304 Serine/threonine-protein kinase mTOR reviewed Kinase MTOR Potency '=' 23280 nM
P12931 BXGT007859 Proto-oncogene tyrosine-protein kinase Src reviewed Kinase SRC Inhibition '=' 41 %
P02545 BXGT005889 Prelamin-A/C reviewed - LMNA Potency '=' 14125 nM
O75496 BXGT005132 Geminin reviewed - GMNN Potency - 29092 nM
Q00532 BXGT012532 Cyclin-dependent kinase-like 1 reviewed Kinase CDKL1 Thermal melting change '=' 0 degrees C
P36507 BXGT009923 Dual specificity mitogen-activated protein kinase kinase 2 reviewed Kinase MAP2K2 Thermal melting change '=' 0 degrees C
P04637 BXGT006243 Cellular tumor antigen p53 reviewed Transcription factor TP53 Potency - 10000 nM
O15118 BXGT004127 NPC intracellular cholesterol transporter 1 reviewed Transporter NPC1 Potency '=' 6513 nM
Q94696 BXGT019553 Luciferase unreviewed - luc Potency '=' 12589 nM
P10636 BXGT007596 Microtubule-associated protein tau reviewed - MAPT Potency '=' 14125 nM
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 reviewed Enzyme NFE2L2 Potency - 16360 nM
O15648 BXGT004185 ATP-dependent 6-phosphofructokinase reviewed - pfk Potency - 3793 nM
Q99700 BXGT019949 Ataxin-2 reviewed Nucleic acid binding ATXN2 Potency - 3162 nM
P00352 BXGT005510 Retinal dehydrogenase 1 reviewed Enzyme ALDH1A1 Potency '=' 28183 nM
O43293 BXGT004584 Death-associated protein kinase 3 reviewed Kinase DAPK3 Thermal melting change '=' 4 degrees C
Q57TT1 BXGT015153 Uncharacterized protein unreviewed - Tb927.8.6820 Potency - 12589 nM
B2RXH2 BXGT002006 Lysine-specific demethylase 4E reviewed - KDM4E Potency '=' 22387 nM
Q9UBT6 BXGT021664 DNA polymerase kappa reviewed - POLK Potency - 31622 nM
P54132 BXGT011032 Bloom syndrome protein reviewed - BLM Potency '=' 25118 nM
P06239 BXGT006427 Tyrosine-protein kinase Lck reviewed Kinase LCK Activity '=' 2 %
Q96KB5 BXGT019685 Lymphokine-activated killer T-cell-originated protein kinase reviewed Kinase PBK Thermal melting change '=' 0 degrees C
P39748 BXGT010134 Flap endonuclease 1 reviewed Enzyme FEN1 Potency - 843 nM
P11021 BXGT007644 Endoplasmic reticulum chaperone BiP reviewed - HSPA5 Potency - 116 nM
P43405 BXGT010386 Tyrosine-protein kinase SYK reviewed Kinase SYK IC50 '=' 10000 nM
P06239 BXGT006427 Tyrosine-protein kinase Lck reviewed Kinase LCK IC50 '=' 66000 nM
Q16637 BXGT013646 Survival motor neuron protein reviewed Epigenetic regulator SMN1 Potency '=' 25118 nM
O96013 BXGT005414 Serine/threonine-protein kinase PAK 4 reviewed Kinase PAK4 Thermal melting change '=' 1 degrees C
Q8IV63 BXGT018341 Inactive serine/threonine-protein kinase VRK3 reviewed Kinase VRK3 Thermal melting change '=' 0 degrees C
O75496 BXGT005132 Geminin reviewed - GMNN Potency '=' 3162 nM
P49798 BXGT010745 Regulator of G-protein signaling 4 reviewed Enzyme modulator RGS4 Potency - 843 nM
Q15746 BXGT013591 Myosin light chain kinase, smooth muscle reviewed Kinase MYLK IC50 '=' 12000 nM
Q9F4F7 BXGT020344 4'-phosphopantetheinyl transferase ffp reviewed - ffp Potency '=' 39810 nM
P18054 BXGT008370 Arachidonate 12-lipoxygenase, 12S-type reviewed Enzyme ALOX12 Potency '=' 4466 nM
O89049 BXGT005293 Thioredoxin reductase 1, cytoplasmic reviewed - Txnrd1 Potency - 7519 nM
Q9UEE5 BXGT021671 Serine/threonine-protein kinase 17A reviewed Kinase STK17A Thermal melting change '=' 0 degrees C
Q99986 BXGT019980 Serine/threonine-protein kinase VRK1 reviewed Kinase VRK1 Thermal melting change '=' 0 degrees C
P49760 BXGT010735 Dual specificity protein kinase CLK2 reviewed Kinase CLK2 Thermal melting change '=' 0 degrees C
Q9NQU5 BXGT021169 Serine/threonine-protein kinase PAK 6 reviewed - PAK6 Thermal melting change '=' 0 degrees C
Q92830 BXGT019379 Histone acetyltransferase KAT2A reviewed - KAT2A Potency - 39810 nM
Q9UNA4 BXGT021785 DNA polymerase iota reviewed - POLI Potency - 15848 nM
Q99549 BXGT019932 M-phase phosphoprotein 8 reviewed Epigenetic regulator MPHOSPH8 Potency - 21192 nM
Q01453 BXGT012588 Peripheral myelin protein 22 reviewed Cellular structure PMP22 Potency '=' 30131 nM
P43405 BXGT010386 Tyrosine-protein kinase SYK reviewed Kinase SYK EC50 '=' 5000 nM
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency '=' 2818 nM
P10636 BXGT007596 Microtubule-associated protein tau reviewed - MAPT Potency '=' 5011 nM
Q99549 BXGT019932 M-phase phosphoprotein 8 reviewed Epigenetic regulator MPHOSPH8 Potency - 39810 nM
O15648 BXGT004185 ATP-dependent 6-phosphofructokinase reviewed - pfk Potency - 8492 nM
P23458 BXGT008868 Tyrosine-protein kinase JAK1 reviewed Kinase JAK1 Thermal melting change '=' 2 degrees C
Q15759 BXGT013595 Mitogen-activated protein kinase 11 reviewed Kinase MAPK11 Thermal melting change '=' 0 degrees C
Q86V86 BXGT017617 Serine/threonine-protein kinase pim-3 reviewed - PIM3 Thermal melting change '=' 3 degrees C
P53350 BXGT010984 Serine/threonine-protein kinase PLK1 reviewed Kinase PLK1 Thermal melting change '=' 2 degrees C
P04062 BXGT006140 Lysosomal acid glucosylceramidase reviewed - GBA Potency - 19952 nM
P10636 BXGT007596 Microtubule-associated protein tau reviewed - MAPT Potency '=' 11220 nM
A0T123 BXGT000970 Calcium dependent protein kinase unreviewed - CDPK IC50 '=' 19000 nM
Q96KQ7 BXGT019687 Histone-lysine N-methyltransferase EHMT2 reviewed Epigenetic regulator EHMT2 Potency - 316 nM
P07378 BXGT006616 Phosphoglycerate kinase, glycosomal reviewed - Potency - 22387 nM
Q92830 BXGT019379 Histone acetyltransferase KAT2A reviewed - KAT2A Potency - 25118 nM
P06239 BXGT006427 Tyrosine-protein kinase Lck reviewed Kinase LCK Inhibition '=' 100 %
P10636 BXGT007596 Microtubule-associated protein tau reviewed - MAPT Potency '=' 7079 nM
P08659 BXGT006805 Luciferin 4-monooxygenase reviewed - Potency - 9528 nM
Q03431 BXGT012714 Parathyroid hormone/parathyroid hormone-related peptide receptor reviewed G-protein coupled receptor PTH1R Potency - 5623 nM
Q9UNA4 BXGT021785 DNA polymerase iota reviewed - POLI Potency - 89125 nM
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 9200 nM
Q96KQ7 BXGT019687 Histone-lysine N-methyltransferase EHMT2 reviewed Epigenetic regulator EHMT2 Potency - 2818 nM
Q04760 BXGT012782 Lactoylglutathione lyase reviewed - GLO1 Inhibition - - -
P10828 BXGT007624 Thyroid hormone receptor beta reviewed Nuclear receptor THRB Potency '=' 70794 nM
P49798 BXGT010745 Regulator of G-protein signaling 4 reviewed Enzyme modulator RGS4 Potency - 75 nM
O75762 BXGT005151 Transient receptor potential cation channel subfamily A member 1 reviewed Ion channel TRPA1 FC '=' 0 -
P10636 BXGT007596 Microtubule-associated protein tau reviewed - MAPT Potency '=' 1778 nM
Q00534 BXGT012533 Cyclin-dependent kinase 6 reviewed Kinase CDK6 Thermal melting change '=' 0 degrees C
Q9BVS4 BXGT020147 Serine/threonine-protein kinase RIO2 reviewed Kinase RIOK2 Thermal melting change '=' 0 degrees C
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 reviewed Enzyme NFE2L2 Potency - 32642 nM
Q9UQM7 BXGT021814 Calcium/calmodulin-dependent protein kinase type II subunit alpha reviewed Kinase CAMK2A Thermal melting change '=' 0 degrees C
Q03164 BXGT012700 Histone-lysine N-methyltransferase 2A reviewed - KMT2A Potency '=' 4466 nM
O00255 BXGT003903 Menin reviewed - MEN1 Potency '=' 4466 nM
O75874 BXGT005157 Isocitrate dehydrogenase [NADP] cytoplasmic reviewed - IDH1 Potency - 23109 nM
P81908 BXGT011959 Cholinesterase reviewed - BCHE Inhibition '=' 2 %
Q9Y253 BXGT022216 DNA polymerase eta reviewed - POLH Potency - 17782 nM
Q9UIF8 BXGT021718 Bromodomain adjacent to zinc finger domain protein 2B reviewed - BAZ2B Potency - 50118 nM
Q96QE3 BXGT019718 ATPase family AAA domain-containing protein 5 reviewed - ATAD5 Potency - 12589 nM
P10828 BXGT007624 Thyroid hormone receptor beta reviewed Nuclear receptor THRB Potency '=' 50118 nM
P51151 BXGT010837 Ras-related protein Rab-9A reviewed - RAB9A Potency '=' 58047 nM
P06239 BXGT006427 Tyrosine-protein kinase Lck reviewed Kinase LCK IC50 '=' 20 ug.mL-1
Q9F4F7 BXGT020344 4'-phosphopantetheinyl transferase ffp reviewed - ffp Potency '=' 50118 nM
P27361 BXGT009176 Mitogen-activated protein kinase 3 reviewed Kinase MAPK3 Thermal melting change '=' 0 degrees C
P02545 BXGT005889 Prelamin-A/C reviewed - LMNA Potency '=' 56 nM
P06239 BXGT006427 Tyrosine-protein kinase Lck reviewed Kinase LCK IC50 '=' 82000 nM
Q13555 BXGT013375 Calcium/calmodulin-dependent protein kinase type II subunit gamma reviewed Kinase CAMK2G Thermal melting change '=' 0 degrees C
P06239 BXGT006427 Tyrosine-protein kinase Lck reviewed Kinase LCK IC50 '=' 5000 nM
Q03164 BXGT012700 Histone-lysine N-methyltransferase 2A reviewed - KMT2A Potency '=' 25118 nM
O00255 BXGT003903 Menin reviewed - MEN1 Potency '=' 25118 nM
O15296 BXGT004148 Arachidonate 15-lipoxygenase B reviewed Enzyme ALOX15B Potency - 4466 nM
P83916 BXGT012025 Chromobox protein homolog 1 reviewed Epigenetic regulator CBX1 Potency - 15848 nM
Q96QE3 BXGT019718 ATPase family AAA domain-containing protein 5 reviewed - ATAD5 Potency - 1157 nM
Q9HC16 BXGT020525 DNA dC->dU-editing enzyme APOBEC-3G reviewed Enzyme APOBEC3G Potency - 35481 nM
Q96QE3 BXGT019718 ATPase family AAA domain-containing protein 5 reviewed - ATAD5 Potency - 5171 nM
P0AE70 BXGT007302 Endoribonuclease toxin MazF reviewed - mazF EC50 '>' 99000 nM
P06746 BXGT006496 DNA polymerase beta reviewed Enzyme POLB Potency '=' 7943 nM
P27695 BXGT009199 DNA-(apurinic or apyrimidinic site) lyase reviewed - APEX1 Potency - 5623 nM
Q9Y468 BXGT022270 Lethal(3)malignant brain tumor-like protein 1 reviewed Epigenetic regulator L3MBTL1 Potency '=' 31622 nM
Q16637 BXGT013646 Survival motor neuron protein reviewed Epigenetic regulator SMN1 Potency '=' 31622 nM
P10636 BXGT007596 Microtubule-associated protein tau reviewed - MAPT Potency '=' 6309 nM
Q9F4F7 BXGT020344 4'-phosphopantetheinyl transferase ffp reviewed - ffp Potency '=' 44668 nM
P49761 BXGT010736 Dual specificity protein kinase CLK3 reviewed Kinase CLK3 Thermal melting change '=' 0 degrees C
P78368 BXGT011840 Casein kinase I isoform gamma-2 reviewed Kinase CSNK1G2 Thermal melting change '=' 0 degrees C
Q9Y6M4 BXGT022335 Casein kinase I isoform gamma-3 reviewed Kinase CSNK1G3 Thermal melting change '=' 0 degrees C
Q9H2G2 BXGT020452 STE20-like serine/threonine-protein kinase reviewed Kinase SLK Thermal melting change '=' 1 degrees C
Q9P289 BXGT021300 Serine/threonine-protein kinase 26 reviewed Kinase STK26 Thermal melting change '=' 1 degrees C
Q99700 BXGT019949 Ataxin-2 reviewed Nucleic acid binding ATXN2 Potency - 31622 nM
Q96KQ7 BXGT019687 Histone-lysine N-methyltransferase EHMT2 reviewed Epigenetic regulator EHMT2 Potency - 1584 nM
P10636 BXGT007596 Microtubule-associated protein tau reviewed - MAPT Potency '=' 7943 nM
Q8IU85 BXGT018333 Calcium/calmodulin-dependent protein kinase type 1D reviewed Kinase CAMK1D Thermal melting change '=' 1 degrees C
O00506 BXGT003932 Serine/threonine-protein kinase 25 reviewed Kinase STK25 Thermal melting change - - -
P28907 BXGT009301 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 reviewed Enzyme CD38 IC50 '>' 100000 nM
O42275 BXGT004559 Acetylcholinesterase reviewed - ache Inhibition '=' 17 %
Q96QE3 BXGT019718 ATPase family AAA domain-containing protein 5 reviewed - ATAD5 Potency - 3661 nM
Q96KQ7 BXGT019687 Histone-lysine N-methyltransferase EHMT2 reviewed Epigenetic regulator EHMT2 Potency - 1412 nM
O97447 BXGT005436 Putative fructose-1,6-bisphosphate aldolase unreviewed - ald Potency '=' 15811 nM
Q16637 BXGT013646 Survival motor neuron protein reviewed Epigenetic regulator SMN1 Potency '=' 15848 nM
Q9UKE5 BXGT021741 TRAF2 and NCK-interacting protein kinase reviewed Kinase TNIK Thermal melting change '=' 0 degrees C
P27695 BXGT009199 DNA-(apurinic or apyrimidinic site) lyase reviewed - APEX1 Potency - 35481 nM
Q9UBT6 BXGT021664 DNA polymerase kappa reviewed - POLK Potency - 1000 nM
P27695 BXGT009199 DNA-(apurinic or apyrimidinic site) lyase reviewed - APEX1 Potency - 28183 nM
Q8WZA2 BXGT019025 Rap guanine nucleotide exchange factor 4 reviewed Enzyme modulator RAPGEF4 Potency - 50118 nM
P49798 BXGT010745 Regulator of G-protein signaling 4 reviewed Enzyme modulator RGS4 Potency - 21192 nM
P02791 BXGT005965 Ferritin light chain reviewed - FTL Potency '=' 39810 nM
P43405 BXGT010386 Tyrosine-protein kinase SYK reviewed Kinase SYK IC50 '=' 5 ug.mL-1
P15428 BXGT008121 15-hydroxyprostaglandin dehydrogenase [NAD(+)] reviewed - HPGD Potency '=' 28183 nM
Q9NR56 BXGT021179 Muscleblind-like protein 1 reviewed Nucleic acid binding MBNL1 Potency - 17782 nM
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 10322 nM
P15428 BXGT008121 15-hydroxyprostaglandin dehydrogenase [NAD(+)] reviewed - HPGD Potency '=' 3162 nM
P43405 BXGT010386 Tyrosine-protein kinase SYK reviewed Kinase SYK IC50 '=' 38000 nM
Q99700 BXGT019949 Ataxin-2 reviewed Nucleic acid binding ATXN2 Potency - 22387 nM
O94925 BXGT005342 Glutaminase kidney isoform, mitochondrial reviewed Enzyme GLS Potency - 35481 nM
P17405 BXGT008304 Sphingomyelin phosphodiesterase reviewed Enzyme SMPD1 Potency - 25118 nM
Q13557 BXGT013376 Calcium/calmodulin-dependent protein kinase type II subunit delta reviewed Kinase CAMK2D Thermal melting change '=' 0 degrees C
Q63470 BXGT016073 Dual specificity tyrosine-phosphorylation-regulated kinase 1A reviewed - Dyrk1a AC50 '=' 7534 nM
P55789 BXGT011126 FAD-linked sulfhydryl oxidase ALR reviewed Enzyme GFER AC50 '=' 689 nM
Q13554 BXGT013374 Calcium/calmodulin-dependent protein kinase type II subunit beta reviewed Kinase CAMK2B Thermal melting change '=' 0 degrees C
Q96KQ7 BXGT019687 Histone-lysine N-methyltransferase EHMT2 reviewed Epigenetic regulator EHMT2 Potency - 670 nM
P07378 BXGT006616 Phosphoglycerate kinase, glycosomal reviewed - Potency - 23934 nM
O89049 BXGT005293 Thioredoxin reductase 1, cytoplasmic reviewed - Txnrd1 Potency - 19952 nM
Q9UBT6 BXGT021664 DNA polymerase kappa reviewed - POLK Potency - 79432 nM
P49841 BXGT010750 Glycogen synthase kinase-3 beta reviewed Kinase GSK3B Thermal melting change '=' 0 degrees C
Q9P286 BXGT021299 Serine/threonine-protein kinase PAK 5 reviewed Kinase PAK5 Thermal melting change '=' 0 degrees C
Q09013 BXGT013023 Myotonin-protein kinase reviewed Kinase DMPK Thermal melting change '=' 0 degrees C
Q9P289 BXGT021300 Serine/threonine-protein kinase 26 reviewed Kinase STK26 Thermal melting change '=' 0 degrees C
P51812 BXGT010893 Ribosomal protein S6 kinase alpha-3 reviewed Kinase RPS6KA3 Thermal melting change '=' 0 degrees C
O75716 BXGT005147 Serine/threonine-protein kinase 16 reviewed Kinase STK16 Thermal melting change '=' 4 degrees C
P03070 BXGT006016 Large T antigen reviewed - IC50 - 16350 nM
O96017 BXGT005415 Serine/threonine-protein kinase Chk2 reviewed Kinase CHEK2 Thermal melting change '=' 1 degrees C
P52564 BXGT010932 Dual specificity mitogen-activated protein kinase kinase 6 reviewed Kinase MAP2K6 Thermal melting change '=' 0 degrees C
Q9NUW8 BXGT021219 Tyrosyl-DNA phosphodiesterase 1 reviewed Enzyme TDP1 Potency - 651 nM
P54646 BXGT011062 5'-AMP-activated protein kinase catalytic subunit alpha-2 reviewed Kinase PRKAA2 Thermal melting change '=' 0 degrees C
Q16659 BXGT013652 Mitogen-activated protein kinase 6 reviewed Kinase MAPK6 Thermal melting change '=' 0 degrees C
P11309 BXGT007685 Serine/threonine-protein kinase pim-1 reviewed Kinase PIM1 Thermal melting change '=' 3 degrees C
P17612 BXGT008322 cAMP-dependent protein kinase catalytic subunit alpha reviewed Kinase PRKACA Thermal melting change '=' 2 degrees C
Q04760 BXGT012782 Lactoylglutathione lyase reviewed - GLO1 Ratio IC50 '=' 14 -
P51812 BXGT010893 Ribosomal protein S6 kinase alpha-3 reviewed Kinase RPS6KA3 Thermal melting change '=' 0 degrees C
Q15208 BXGT013550 Serine/threonine-protein kinase 38 reviewed Kinase STK38 Thermal melting change '=' 1 degrees C
Q9HCP0 BXGT020536 Casein kinase I isoform gamma-1 reviewed Kinase CSNK1G1 Thermal melting change '=' 0 degrees C
O95747 BXGT005393 Serine/threonine-protein kinase OSR1 reviewed Kinase OXSR1 Thermal melting change '=' 1 degrees C
P27695 BXGT009199 DNA-(apurinic or apyrimidinic site) lyase reviewed - APEX1 Potency - 794 nM
P24941 BXGT009002 Cyclin-dependent kinase 2 reviewed Kinase CDK2 Thermal melting change '=' 1 degrees C
Q99683 BXGT019947 Mitogen-activated protein kinase kinase kinase 5 reviewed Kinase MAP3K5 Thermal melting change '=' 0 degrees C
Q9HC98 BXGT020528 Serine/threonine-protein kinase Nek6 reviewed Kinase NEK6 Thermal melting change '=' 0 degrees C
O94804 BXGT005334 Serine/threonine-protein kinase 10 reviewed Kinase STK10 Thermal melting change '=' 0 degrees C
P51955 BXGT010908 Serine/threonine-protein kinase Nek2 reviewed Kinase NEK2 Thermal melting change '=' 1 degrees C
O15530 BXGT004177 3-phosphoinositide-dependent protein kinase 1 reviewed Kinase PDPK1 Thermal melting change '=' 0 degrees C
Q96NX5 BXGT019702 Calcium/calmodulin-dependent protein kinase type 1G reviewed Kinase CAMK1G Thermal melting change '=' 0 degrees C
Q16566 BXGT013639 Calcium/calmodulin-dependent protein kinase type IV reviewed Kinase CAMK4 Thermal melting change '=' 0 degrees C
P43405 BXGT010386 Tyrosine-protein kinase SYK reviewed Kinase SYK EC50 '=' 25000 nM
O75164 BXGT005104 Lysine-specific demethylase 4A reviewed - KDM4A Potency - 44668 nM
Q86Y07 BXGT017631 Serine/threonine-protein kinase VRK2 reviewed Kinase VRK2 Thermal melting change '=' 0 degrees C
P15289 BXGT008102 Arylsulfatase A reviewed Enzyme ARSA Potency - 23934 nM
O75762 BXGT005151 Transient receptor potential cation channel subfamily A member 1 reviewed Ion channel TRPA1 FC '=' 0 -
Q00536 BXGT012535 Cyclin-dependent kinase 16 reviewed Kinase CDK16 Thermal melting change '=' 0 degrees C
O00444 BXGT003921 Serine/threonine-protein kinase PLK4 reviewed Kinase PLK4 Thermal melting change '=' 1 degrees C
P49759 BXGT010734 Dual specificity protein kinase CLK1 reviewed Kinase CLK1 Thermal melting change '=' 0 degrees C
Q9P1W9 BXGT021296 Serine/threonine-protein kinase pim-2 reviewed Kinase PIM2 Thermal melting change '=' 2 degrees C
Q13043 BXGT013307 Serine/threonine-protein kinase 4 reviewed Kinase STK4 Thermal melting change '=' 0 degrees C
Q04760 BXGT012782 Lactoylglutathione lyase reviewed - GLO1 IC50 '=' 760 nM
Q96RR4 BXGT019734 Calcium/calmodulin-dependent protein kinase kinase 2 reviewed Kinase CAMKK2 Thermal melting change '=' 0 degrees C
P21728 BXGT008686 D(1A) dopamine receptor reviewed G-protein coupled receptor DRD1 Potency - 580 nM
Q96KQ7 BXGT019687 Histone-lysine N-methyltransferase EHMT2 reviewed Epigenetic regulator EHMT2 Potency - 1778 nM
P03372 BXGT006059 Estrogen receptor reviewed Nuclear receptor ESR1 FC '=' 0 -
Q92731 BXGT019366 Estrogen receptor beta reviewed Nuclear receptor ESR2 FC '=' 0 -
P03372 BXGT006059 Estrogen receptor reviewed Nuclear receptor ESR1 FC '=' 0 -
Q92731 BXGT019366 Estrogen receptor beta reviewed Nuclear receptor ESR2 FC '=' 0 -
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF00129 Parsnip Pastinaca sativa Vegetables
BXGF00204 Common grape Vitis vinifera Fruits
BXGF00213 European cranberry Vaccinium oxycoccos Fruits
BXGF00401 American pokeweed Phytolacca americana Vegetables
BXGF00931 Ipomoea digitata Ipomoea digitata Medicinal Plant
BXGF01034 Annona cornifolia Annona cornifolia Human Edible Plant
BXGF01126 Polygonum cuspidatum Polygonum cuspidatum Medicinal Plant
BXGF01174 Salvia syriaca Salvia syriaca Others
BXGF01204 Solanum laxum Solanum laxum Medicinal Plant
BXGF01228 Ageratina adenophora Ageratina adenophora Medicinal Plant
BXGF01241 Eleutherococcus sessiliflorus Eleutherococcus sessiliflorus Medicinal Plant
BXGF01456 Eucalyptus melliodora Eucalyptus melliodora Others
BXGF01555 Scutellaria amoena Scutellaria amoena Medicinal Plant
BXGF01614 Goniothalamus malayanus Goniothalamus malayanus Others
BXGF01834 Lysimachia mauritiana Lysimachia mauritiana Others
BXGF01883 Swertia franchetiana Swertia franchetiana Medicinal Plant
BXGF01989 Helipterum roseum Helipterum roseum Others
BXGF02050 Hedysarum connatum Hedysarum connatum Others
BXGF02088 Zanthoxylum tetraspermum Zanthoxylum tetraspermum Medicinal Plant
BXGF02125 Artemisia assoana Artemisia assoana Others
BXGF02183 Dumortiera hirsuta Dumortiera hirsuta Medicinal Plant
BXGF02246 Lepisorus ussuriensis Lepisorus ussuriensis Medicinal Plant
BXGF02295 Alstonia spathulata Alstonia spathulata Others
BXGF02326 Phoebe pittieri Phoebe pittieri Others
BXGF02361 Hypericum laricifolium Hypericum laricifolium Medicinal Plant
BXGF02400 Hylotelephium telephium Hylotelephium telephium Medicinal Plant
BXGF02410 Adiantum lunulatum Adiantum lunulatum Medicinal Plant
BXGF02460 Peltostigma guatemalense Peltostigma guatemalense Others
BXGF02491 Acacia adunca Acacia adunca Others
BXGF02515 Viguiera incana Viguiera incana Others
BXGF02529 Astragalus sempervirens Astragalus sempervirens Others
BXGF02531 Caragana tibetica Caragana tibetica Medicinal Plant
BXGF02554 Marrubium anisodon Marrubium anisodon Medicinal Plant
BXGF02593 Wikstroemia retusa Wikstroemia retusa Others
BXGF02606 Naucleopsis ternstroemiiflora Naucleopsis ternstroemiiflora Others
BXGF02662 Rheum wittrocki Rheum wittrocki Medicinal Plant
BXGF02773 Carica pennata Carica pennata Others
BXGF03131 Astragalus cibarius Astragalus cibarius Medicinal Plant
BXGF03158 Rheum officinale Rheum officinale Medicinal Plant
BXGF03205 Veratrum dahuricum Veratrum dahuricum Others
BXGF03291 Vernonia menthaefolia Vernonia menthaefolia Others
BXGF03318 Capsicum tetragonum Capsicum tetragonum Others
BXGF03353 Aconitum heterophylloides Aconitum heterophylloides Others
BXGF03446 Vouacapoua macropetala Vouacapoua macropetala Medicinal Plant
BXGF03739 Gymnosporia diversifolia Gymnosporia diversifolia Others
BXGF03934 Lycoris traubii Lycoris traubii Others
BXGF03947 Rumex maritimus Rumex maritimus Medicinal Plant
BXGF03988 Rheum coreanum Rheum coreanum Others
BXGF04053 Smilax china Smilax china Medicinal Plant
BXGF04209 Chaenomeles sinensis Chaenomeles sinensis Medicinal Plant
BXGF04350 Lygodium flexuosum Lygodium flexuosum Medicinal Plant
BXGF04539 Rheum palmatum Rheum palmatum Medicinal Plant
BXGF04709 Strychnos staudtii Strychnos staudtii Others
BXGF04727 Dictyoloma incanescens Dictyoloma incanescens Others
BXGF04738 Saccharum spontaneum Saccharum spontaneum Medicinal Plant
BXGF04746 Crotalaria anagyroides Crotalaria anagyroides Medicinal Plant
BXGF04778 Dasymaschalon sootepense Dasymaschalon sootepense Others
BXGF04782 Croton poilanei Croton poilanei Others
BXGF04794 Tsuga mertensiana Tsuga mertensiana Medicinal Plant
BXGF04820 Panax ginseng Panax ginseng 0
BXGF04834 Guatteria melosma Guatteria melosma Others
BXGF04860 Securinega melanthesoides Securinega melanthesoides Others
BXGF04865 Euonymus sachalinensis Euonymus sachalinensis Medicinal Plant
BXGF04870 Felicia erigeroides Felicia erigeroides Others
BXGF04879 Lupinus paniculatus Lupinus paniculatus Others
BXGF04886 Boehmeria nivea Boehmeria nivea Medicinal Plant
BXGF05046 stuhlmannia moavi stuhlmannia moavi Others
BXGF05187 Calostephane divaricata Calostephane divaricata Others
BXGF05398 Fritillaria persica Fritillaria persica Medicinal Plant
BXGF05616 Trinia scabra Trinia scabra Others
BXGF05693 Picea jezoensis var. jezoensis Picea jezoensis var. jezoensis Medicinal Plant
BXGF05742 Caragana aurantiaca Caragana aurantiaca Others
BXGF05787 Smilax glabra Smilax glabra Medicinal Plant
BXGF05862 Premna odorata Premna odorata Medicinal Plant
BXGF05877 Rheum tanguticum Rheum tanguticum Medicinal Plant
BXGF05899 Coprosma lucida Coprosma lucida Medicinal Plant
BXGF06037 Cotyledon secunda Cotyledon secunda Others
BXGF06095 Rheum undulatum Rheum undulatum Medicinal Plant
BXGF06165 Phalaenopsis cornu-cervi Phalaenopsis cornu-cervi Others
BXGF06227 Rauvolfia vomitoria Rauvolfia vomitoria Medicinal Plant
BXGF06237 Gnetum latifolium Gnetum latifolium Medicinal Plant
BXGF06239 Pericopsis angolensis Pericopsis angolensis Medicinal Plant
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease