acompound

General Compound Information
BXGC Id	BXGC0044019
Compound Name	(R)-Reticuline
Structure
Formula	C19H23NO4
InchiKey	BHLYRWXGMIUIHG-OAHLLOKOSA-N
SMILES	COc1ccc(cc1O)C[C@H]1N(C)CCc2c1cc(O)c(c2)OC
Inchi	InChI=1S/C19H23NO4/c1-20-7-6-13-10-19(24-3)17(22)11-14(13)15(20)8-12-4-5-18(23-2)16(21)9-12/h4-5,9-11,15,21-22H,6-8H2,1-3H3/t15-/m1/s1
IUPAC	(1R)-1-[(3-hydroxy-4-methoxyphenyl)methyl]-6-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-ol
Molecular Weight	329.16
Pubchem Id	440586
Chembl Id	CHEMBL401501

Targets of Information Source

DrugBank

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type

PDB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1

Binding DB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM

CHEMBL

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
P35372	BXGT009823	Mu-type opioid receptor	reviewed	G-protein coupled receptor	OPRM1	EC50	-	-	-
O42275	BXGT004559	Acetylcholinesterase	reviewed	-	ache	Inhibition	'='	61	%
P35372	BXGT009823	Mu-type opioid receptor	reviewed	G-protein coupled receptor	OPRM1	Emax	'='	15	%
P35372	BXGT009823	Mu-type opioid receptor	reviewed	G-protein coupled receptor	OPRM1	Ki	-	-	-
P81908	BXGT011959	Cholinesterase	reviewed	-	BCHE	Inhibition	-	-	-
O42275	BXGT004559	Acetylcholinesterase	reviewed	-	ache	IC50	-	-	-
O42275	BXGT004559	Acetylcholinesterase	reviewed	-	ache	Inhibition	-	-	-

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF00014	Custard apple	Annona reticulata	Fruits
BXGF00402	Opium poppy	Papaver somniferum	Herbs and Spices
BXGF00446	Sugar apple	Annona squamosa	Fruits
BXGF00850	Tinospora capillipes	Tinospora capillipes	Others
BXGF00883	Chrozophora prostrata	Chrozophora prostrata	Medicinal Plant
BXGF00891	Artabotrys uncinatus	Artabotrys uncinatus	Others
BXGF00962	Machilus thunbergii	Machilus thunbergii	Medicinal Plant
BXGF01237	Magnolia obovata	Magnolia obovata	Medicinal Plant
BXGF01660	Thalictrum foliolosum	Thalictrum foliolosum	Medicinal Plant
BXGF02557	Lamprocapnos spectabilis	Lamprocapnos spectabilis	Others
BXGF02736	Larix decidua	Larix decidua	Medicinal Plant
BXGF03870	Aloe microstigma	Aloe microstigma	Others
BXGF04006	Corydalis ternata	Corydalis ternata	Others
BXGF04085	Paratinospora sagittata	Paratinospora sagittata	Others
BXGF04921	Dicentra spectabilis	Dicentra spectabilis	Medicinal Plant
BXGF05264	Magnolia officinalis	Magnolia officinalis	Medicinal Plant
BXGF05319	Lindera aggregata	Lindera aggregata	Others
BXGF05622	Corydalis incisa	Corydalis incisa	Medicinal Plant
BXGF05626	Annona glabra	Annona glabra	Medicinal Plant
BXGF05702	Cinnamomum camphora	Cinnamomum camphora	Medicinal Plant
BXGF05994	Corydalis yanhusuo	Corydalis yanhusuo	Medicinal Plant
BXGF06188	Swertia mussotii	Swertia mussotii	Medicinal Plant

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}