Showing entry for Lactose, Anhydrous


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0048001
Compound NameLactose, Anhydrous
Structure
FormulaC12H22O11
InchiKeyGUBGYTABKSRVRQ-DCSYEGIMSA-N
SMILESOC[C@H]1O[C@@H](O)[C@@H]([C@H]([C@@H]1O[C@@H]1O[C@H](CO)[C@@H]([C@@H]([C@H]1O)O)O)O)O
InchiInChI=1S/C12H22O11/c13-1-3-5(15)6(16)9(19)12(22-3)23-10-4(2-14)21-11(20)8(18)7(10)17/h3-20H,1-2H2/t3-,4-,5+,6+,7-,8-,9-,10-,11-,12+/m1/s1
IUPAC(2R,3R,4S,5R,6S)-2-(hydroxymethyl)-6-[(2R,3S,4R,5R,6R)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxane-3,4,5-triol
Molecular Weight342.12
Pubchem Id6134
Chembl IdCHEMBL417016
Targets of Information Source
DrugBank n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
PDB LAT
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
P04958 BXGT006288 Tetanus toxin reviewed tetX - - - - -
P14769 BXGT008050 N-acetyllactosaminide alpha-1,3-galactosyltransferase reviewed GGTA1 - - - 2680000 -
P83410 BXGT011990 Lectin reviewed - - - - -
P83410 BXGT011990 Lectin reviewed - - - 320000 -
Q9YIC2 BXGT022388 Congerin-2 reviewed - - - - -
Q7SI98 BXGT017100 Beta-xylanase unreviewed - - - - -
P00722 BXGT005626 Beta-galactosidase reviewed lacZ - - - - -
P26514 BXGT009118 Endo-1,4-beta-xylanase A reviewed xlnA - - - - -
Q26966 BXGT013922 Trans-sialidase unreviewed - - - - -
P14769 BXGT008050 N-acetyllactosaminide alpha-1,3-galactosyltransferase reviewed GGTA1 - - - 2690000 -
P81446 BXGT011949 Beta-galactoside-specific lectin 1 reviewed - - - - -
P02872 BXGT005978 Galactose-binding lectin reviewed - - - - -
P01552 BXGT005764 Enterotoxin type B reviewed entB - - - - -
P16404 BXGT008223 Lectin reviewed - - - - -
Q9NZD2 BXGT021270 Glycolipid transfer protein reviewed GLTP Transporter - - - -
Q6YD91 BXGT016620 Lectin unreviewed ECL - - - - -
P14769 BXGT008050 N-acetyllactosaminide alpha-1,3-galactosyltransferase reviewed GGTA1 - - - - -
P09382 BXGT006882 Galectin-1 reviewed LGALS1 Signaling - - - 2200
Q7LIJ0 BXGT017000 Glucanase unreviewed cbh1-4 - - - 77000 -
Q9CP67 BXGT020246 Uncharacterized protein unreviewed PM0188 - - - - -
P17931 BXGT008356 Galectin-3 reviewed LGALS3 Signaling - - 260000 -
P02872 BXGT005978 Galactose-binding lectin reviewed - 1370000 - - -
Q7Z8V1 BXGT017263 Hemolytic lectin LSLa unreviewed lsla - - - - -
E1C0Z4 BXGT003070 Galectin unreviewed LGALS2 - - - - 6000
O00214 BXGT003897 Galectin-8 reviewed LGALS8 Signaling - - - -
Q6WY08 BXGT016601 Anti-tumor lectin reviewed - - - - -
P17931 BXGT008356 Galectin-3 reviewed LGALS3 Signaling - - - -
P33183 BXGT009700 Nigrin b reviewed - - - - -
O00182 BXGT003889 Galectin-9 reviewed LGALS9 Signaling - - - -
P11762 BXGT007744 Galectin-1 reviewed Lgals1 - - - - -
B2ZRS9 BXGT002022 Ricin B-like lectin reviewed - - - - -
D9J2T9 BXGT003028 Ribosome inactivating protein unreviewed RIP - - - - -
A3DD67 BXGT001129 Ricin B lectin unreviewed Cthe_0661 - - - - -
P17931 BXGT008356 Galectin-3 reviewed LGALS3 Signaling - - 231000 -
Q6VBJ0 BXGT016578 Epa1p unreviewed EPA1 - - - 31900 -
O00214 BXGT003897 Galectin-8 reviewed LGALS8 Signaling - - - 13000
Q6FX55 BXGT016291 Uncharacterized protein unreviewed EPA6 - - - - -
B4UMX2 BXGT002144 Uncharacterized protein unreviewed EPA9 - - - - -
P62694 BXGT011449 Exoglucanase 1 reviewed cbh1 - - - - -
P31522 BXGT009548 pH 6 antigen reviewed psaA - - - - -
R4GRU6 BXGT022495 BEL beta-trefoil unreviewed - - - - -
F6KMV5 BXGT003295 Ricin B-like lectin unreviewed - - - - -
P56470 BXGT011173 Galectin-4 reviewed LGALS4 Signaling - - - -
P56470 BXGT011173 Galectin-4 reviewed LGALS4 Signaling - - 1900000 -
B7X8M2 BXGT002275 rRNA N-glycosidase unreviewed MCL1 - - - - -
P56470 BXGT011173 Galectin-4 reviewed LGALS4 Signaling - - 1300000 -
Q8A6L0 BXGT017842 Retaining alpha-galactosidase reviewed BT_1871 - - - - -
U3KRF8 BXGT022566 Seed lectin (Fragments) reviewed - - - - -
Q05315 BXGT012811 Galectin-10 reviewed CLC Signaling - - - -
A0A2Z5WLM1 BXGT000796 Galactose-specific lectin unreviewed AJLec - - - - 11300
Q9UHV8 BXGT021706 Galactoside-binding soluble lectin 13 reviewed LGALS13 Signaling - - - -
Binding DB 50370453
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
reviewed BXGT008356 Galectin-3 reviewed Signaling LGALS3 - - 230000 -
reviewed BXGT008356 Galectin-3 reviewed Signaling LGALS3 - - 93 -
reviewed BXGT008195 Galectin-3 reviewed Lgals3 - - 222000 -
reviewed BXGT008356 Galectin-3 reviewed Signaling LGALS3 - 800000 - -
reviewed BXGT006882 Galectin-1 reviewed Signaling LGALS1 - 800000 - -
reviewed BXGT003889 Galectin-9 reviewed Signaling LGALS9 - - 23000 -
reviewed BXGT010598 Galectin-7 reviewed Signaling LGALS7 - - 110000 -
reviewed BXGT006882 Galectin-1 reviewed Signaling LGALS1 - - 420000 -
reviewed BXGT008356 Galectin-3 reviewed Signaling LGALS3 - - 110000 -
reviewed BXGT003897 Galectin-8 reviewed Signaling LGALS8 - - 62000 -
reviewed BXGT006641 Beta-galactoside-binding lectin reviewed CG-1B - 4000000 - -
CHEMBL CHEMBL417016
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
Q8KHJ3 BXGT018422 Alpha 1,4 galactosyltransferase unreviewed - lgtC Kcat '=' 160 /s
O00214 BXGT003897 Galectin-8 reviewed Signaling LGALS8 Kd '=' 62000 nM
O00182 BXGT003889 Galectin-9 reviewed Signaling LGALS9 Kd '=' 23000 nM
Q6P4F1 BXGT016448 Alpha-(1,3)-fucosyltransferase 10 reviewed Enzyme FUT10 Relative activity '=' 120 -
P09382 BXGT006882 Galectin-1 reviewed Signaling LGALS1 Kd '=' 420000 nM
Q8KHJ3 BXGT018422 Alpha 1,4 galactosyltransferase unreviewed - lgtC Kcat/Km '=' 240 /mM/min
A4GTP0 BXGT001218 Galectin-3 unreviewed - IC50 '=' 4500000 nM
P09382 BXGT006882 Galectin-1 reviewed Signaling LGALS1 Activity '=' 0 mM
P17931 BXGT008356 Galectin-3 reviewed Signaling LGALS3 Activity '=' 1 -
P17931 BXGT008356 Galectin-3 reviewed Signaling LGALS3 Inhibition - - -
P09382 BXGT006882 Galectin-1 reviewed Signaling LGALS1 IC50 '=' 800000 nM
Q8KHJ3 BXGT018422 Alpha 1,4 galactosyltransferase unreviewed - lgtC Km '=' 40000000 nM
P17931 BXGT008356 Galectin-3 reviewed Signaling LGALS3 Inhibition '=' 44 %
A4GTP0 BXGT001218 Galectin-3 unreviewed - IC50 '=' 1100000 nM
P07583 BXGT006641 Beta-galactoside-binding lectin reviewed - CG-1B IC50 '=' 4000000 nM
P47929 BXGT010598 Galectin-7 reviewed Signaling LGALS7 Kd '=' 110000 nM
A4GTP0 BXGT001218 Galectin-3 unreviewed - Inhibition '=' 67 %
A4GTP0 BXGT001218 Galectin-3 unreviewed - Inhibition '=' 75 %
P16110 BXGT008195 Galectin-3 reviewed - Lgals3 IC50 '=' 1000000 nM
P17931 BXGT008356 Galectin-3 reviewed Signaling LGALS3 Kd '=' 92600 nM
P17931 BXGT008356 Galectin-3 reviewed Signaling LGALS3 Kd '=' 230000 nM
P09382 BXGT006882 Galectin-1 reviewed Signaling LGALS1 Inhibition '=' 54 %
P17931 BXGT008356 Galectin-3 reviewed Signaling LGALS3 Activity '=' 0 mM
P17931 BXGT008356 Galectin-3 reviewed Signaling LGALS3 Kd '=' 110000 nM
P16110 BXGT008195 Galectin-3 reviewed - Lgals3 Kd '=' 222000 nM
P16110 BXGT008195 Galectin-3 reviewed - Lgals3 Affinity '=' 20 -
P09382 BXGT006882 Galectin-1 reviewed Signaling LGALS1 Activity '=' 1 -
O00182 BXGT003889 Galectin-9 reviewed Signaling LGALS9 Inhibition - - -
O00214 BXGT003897 Galectin-8 reviewed Signaling LGALS8 Inhibition - - -
P17931 BXGT008356 Galectin-3 reviewed Signaling LGALS3 IC50 '=' 800000 nM
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF01911 Bupleurum scorzonerifolium Bupleurum scorzonerifolium Medicinal Plant
BXGF04875 Bupleurum chinense Bupleurum chinense Medicinal Plant
BXGF04889 Pogostemon cablin Pogostemon cablin Medicinal Plant
BXGF04981 Bupleurum falcatum Bupleurum falcatum Medicinal Plant
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease