acompound

Showing entry for Cytidine

General Compound Information
BXGC Id	BXGC0048596
Compound Name	Cytidine
Structure
Formula	C9H13N3O5
InchiKey	UHDGCWIWMRVCDJ-XVFCMESISA-N
SMILES	OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1ccc(=N)nc1O
Inchi	InChI=1S/C9H13N3O5/c10-5-1-2-12(9(16)11-5)8-7(15)6(14)4(3-13)17-8/h1-2,4,6-8,13-15H,3H2,(H2,10,11,16)/t4-,6-,7-,8-/m1/s1
IUPAC	4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
Molecular Weight	243.09
Pubchem Id	6175
Chembl Id	CHEMBL95606

Targets of Information Source

DrugBank

DB02097

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Q9BZX2	BXGT020204	Uridine-cytidine kinase 2	reviewed	Kinase	UCK2	experimental	-

PDB

CTN

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Q9BZX2	BXGT020204	Uridine-cytidine kinase 2	reviewed	UCK2	Kinase	-	-	-	-
P56389	BXGT011166	Cytidine deaminase	reviewed	Cda	-	-	-	-	-
O67060	BXGT004974	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase	reviewed	ispE	-	-	-	-	-
A0A0H2VD83	BXGT000290	Uncharacterized protein	unreviewed	c4898	-	-	-	-	-
Q3JRA0	BXGT014460	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	reviewed	ispF	-	-	-	-	-
Q8ZMF7	BXGT019213	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	reviewed	ispF	-	-	-	-	-
P60390	BXGT011301	Ribosomal RNA small subunit methyltransferase H	reviewed	rsmH	-	-	-	-	-
Q5SKR5	BXGT015776	Uridine kinase	reviewed	udk	-	-	-	-	-
P15907	BXGT008168	Beta-galactoside alpha-2,6-sialyltransferase 1	reviewed	ST6GAL1	-	-	-	-	-
D0C9L6	BXGT002668	Peptidyl-tRNA hydrolase	unreviewed	pth	-	-	-	5.3	-
Q2KDX6	BXGT014114	Probable sugar kinase protein	unreviewed	RHE_CH00135	-	-	-	-	-
Q82Y41	BXGT017428	Cytidine and deoxycytidylate deaminase zinc-binding region	unreviewed	NE0047	-	-	-	-	43000
Q9W197	BXGT021910	7-methylguanosine phosphate-specific 5'-nucleotidase	reviewed	cN-IIIB	-	-	-	-	-
Q9KPL5	BXGT020968	Nucleoside permease	unreviewed	VC_2352	-	-	-	-	-
D9J2T9	BXGT003028	Ribosome inactivating protein	unreviewed	RIP	-	-	-	-	-
Q9K4U1	BXGT020874	Uridine phosphorylase	unreviewed	udp	-	-	-	-	-
Q7CP66	BXGT016935	Thymidine phosphorylase	reviewed	deoA	-	-	-	-	-
A0A0U3AGT1	BXGT000619	Purine nucleoside phosphorylase	unreviewed		-	-	-	-	-
P9WPQ5	BXGT012471	ATP-dependent dethiobiotin synthetase BioD	reviewed	bioD	-	-	-	-	-

Binding DB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM

CHEMBL

CHEMBL95606

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
P27707	BXGT009201	Deoxycytidine kinase	reviewed	Kinase	DCK	Kcat	'='	0	/s
P22629	BXGT008788	Streptavidin	reviewed	-		Activity	-	-	-
Q12809	BXGT013267	Potassium voltage-gated channel subfamily H member 2	reviewed	Ion channel	KCNH2	Inhibition	'='	0	%
P62344	BXGT011426	Calcium-dependent protein kinase 1	reviewed	-	CPK1	IC50	'>'	1000	nM
P83916	BXGT012025	Chromobox protein homolog 1	reviewed	Epigenetic regulator	CBX1	Potency	-	56234	nM
P56389	BXGT011166	Cytidine deaminase	reviewed	-	Cda	Relative initial rate	'='	100	-
P27707	BXGT009201	Deoxycytidine kinase	reviewed	Kinase	DCK	Km	'='	6600	nM
Q9HA47	BXGT020503	Uridine-cytidine kinase 1	reviewed	Kinase	UCK1	Kcat	'='	0	/s
P27707	BXGT009201	Deoxycytidine kinase	reviewed	Kinase	DCK	Kcat/Km	'='	0	/uM/s
Q9HA47	BXGT020503	Uridine-cytidine kinase 1	reviewed	Kinase	UCK1	Kcat/Km	'='	0	/uM/s
Q9HA47	BXGT020503	Uridine-cytidine kinase 1	reviewed	Kinase	UCK1	Km	'='	131000	nM
D3ZGQ2	BXGT002918	Thymidine kinase 2	unreviewed	-	Tk2	Inhibition	'='	13	%
P11166	BXGT007661	Solute carrier family 2, facilitated glucose transporter member 1	reviewed	Transporter	SLC2A1	IC50	'>'	12000	nM
P32320	BXGT009622	Cytidine deaminase	reviewed	Enzyme	CDA	Kcat	'='	5	/s
P32320	BXGT009622	Cytidine deaminase	reviewed	Enzyme	CDA	Km	'='	40000	nM
P32320	BXGT009622	Cytidine deaminase	reviewed	Enzyme	CDA	Kcat/Km	'='	0	/uM/s
P27158	BXGT009160	Thymidine kinase, cytosolic	reviewed	-	Tk1	Inhibition	'='	1	%
Q8I5R7	BXGT018228	Proline--tRNA ligase	reviewed	-	proRS	IC50	'>'	2500	nM
O96214	BXGT005421	Uncharacterized protein	unreviewed	-	pk7	IC50	'>'	1000	nM
Q9Y6L6	BXGT022334	Solute carrier organic anion transporter family member 1B1	reviewed	Transporter	SLCO1B1	Inhibition	'='	99	%
Q25917	BXGT013905	Mitogen-activated protein kinase	unreviewed	-	map-2	IC50	'>'	1000	nM
O97467	BXGT005437	Hexose transporter 1	unreviewed	-	ht1	IC50	'>'	12000	nM
Q8IDJ8	BXGT018251	Lysine--tRNA ligase	unreviewed	-	PF3D7_1350100	IC50	'>'	2500	nM
O77239	BXGT005189	Cdk-related protein kinase 6	unreviewed	-	PK6	IC50	'>'	1000	nM
O61059	BXGT004913	Glucose transporter	unreviewed	-	LmGT2	IC50	'>'	12000	nM
Q9NPD5	BXGT021151	Solute carrier organic anion transporter family member 1B3	reviewed	Transporter	SLCO1B3	Inhibition	'='	114	%
Q8IBS5	BXGT018243	Calcium-dependent protein kinase 4	reviewed	-	CPK4	IC50	'>'	1000	nM
P27695	BXGT009199	DNA-(apurinic or apyrimidinic site) lyase	reviewed	-	APEX1	Potency	-	354	nM
Q12809	BXGT013267	Potassium voltage-gated channel subfamily H member 2	reviewed	Ion channel	KCNH2	Inhibition	'='	8	%

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF00337	Ginkgo nuts	Ginkgo biloba	Herbs and Spices
BXGF00522	Narrowleaf cattail	Typha angustifolia	Vegetables
BXGF01093	Fritillaria pallidiflora	Fritillaria pallidiflora	Medicinal Plant
BXGF01347	Fritillaria delavayi	Fritillaria delavayi	Medicinal Plant
BXGF01413	Fritillaria verticillata	Fritillaria verticillata	Medicinal Plant
BXGF01479	Fritillaria cirrhosa	Fritillaria cirrhosa	Medicinal Plant
BXGF01776	Fritillaria prezewalskii	Fritillaria prezewalskii	Others
BXGF01913	Fritillaria unibracteata	Fritillaria unibracteata	Medicinal Plant
BXGF02725	Fritillaria walujewii	Fritillaria walujewii	Medicinal Plant
BXGF02815	Pinellia ternata	Pinellia ternata	Medicinal Plant
BXGF03348	Panax notoginseng	Panax notoginseng	Medicinal Plant
BXGF03439	Fritillaria przewalskii	Fritillaria przewalskii	Medicinal Plant
BXGF03811	Euryale ferox	Euryale ferox	Medicinal Plant
BXGF04103	Fritillaria taipaiensis	Fritillaria taipaiensis	Others
BXGF04600	Typha orientalis	Typha orientalis	Medicinal Plant
BXGF05257	Morinda citrifolia	Morinda citrifolia	Medicinal Plant
BXGF05281	Fritillaria thunbergii	Fritillaria thunbergii	Medicinal Plant
BXGF05297	Isatis tinctoria	Isatis tinctoria	Medicinal Plant
BXGF05505	Fritillaria ussuriensis	Fritillaria ussuriensis	Medicinal Plant
BXGF05571	Ziziphus jujuba	Ziziphus jujuba	Medicinal Plant
BXGF06143	Persicaria tinctoria	Persicaria tinctoria	Medicinal Plant

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}