Showing entry for L-1-Deoxynojirimycin


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0049562
Compound NameL-1-Deoxynojirimycin
Structure
FormulaC6H13NO4
InchiKeyLXBIFEVIBLOUGU-FSIIMWSLSA-N
SMILESOC[C@@H]1NC[C@H]([C@@H]([C@H]1O)O)O
InchiInChI=1S/C6H13NO4/c8-2-3-5(10)6(11)4(9)1-7-3/h3-11H,1-2H2/t3-,4+,5-,6-/m0/s1
IUPAC(2S,3S,4S,5R)-2-(hydroxymethyl)piperidine-3,4,5-triol
Molecular Weight163.08
Pubchem Id44387838
Chembl IdCHEMBL369297
Targets of Information Source
DrugBank n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
PDB n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Binding DB 50163447
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
reviewed BXGT008901 Sucrase-isomaltase, intestinal reviewed Si - 150000 - -
reviewed BXGT015223 Beta-galactosidase reviewed GLB1 - 560000 - -
reviewed BXGT012651 Lactase-phlorizin hydrolase reviewed Lct - 317000 - -
reviewed BXGT008901 Sucrase-isomaltase, intestinal reviewed Si - 18000 - -
reviewed BXGT008901 Sucrase-isomaltase, intestinal reviewed Si - 28000 - -
reviewed BXGT020447 Cytosolic beta-glucosidase reviewed Enzyme GBA3 - 980000 - -
CHEMBL CHEMBL369297
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
Q2KIM0 BXGT014117 Tissue alpha-L-fucosidase reviewed - FUCA1 Inhibition '<' 50 %
Q9LGC6 BXGT021076 Putative alpha-glucosidase unreviewed - P0504H10.9 IC50 '=' 4300 nM
P23739 BXGT008901 Sucrase-isomaltase, intestinal reviewed - Si IC50 '=' 18000 nM
O43451 BXGT004594 Maltase-glucoamylase, intestinal reviewed Enzyme MGAM Inhibition '<' 50 %
Q9SEH8 BXGT021581 alpha-1,2-Mannosidase unreviewed - Man1 Inhibition '<' 50 %
O00462 BXGT003925 Beta-mannosidase reviewed Enzyme MANBA Inhibition '<' 50 %
P04066 BXGT006142 Tissue alpha-L-fucosidase reviewed - FUCA1 Inhibition '<' 50 %
D3ZUM4 BXGT002920 Beta-galactosidase unreviewed - Glb1 Inhibition '<' 50 %
Q9H227 BXGT020447 Cytosolic beta-glucosidase reviewed Enzyme GBA3 IC50 '=' 980000 nM
Q9Y2E5 BXGT022231 Epididymis-specific alpha-mannosidase reviewed - MAN2B2 Inhibition '<' 50 %
O00754 BXGT003944 Lysosomal alpha-mannosidase reviewed - MAN2B1 Inhibition '<' 50 %
P06280 BXGT006433 Alpha-galactosidase A reviewed - GLA Inhibition '<' 50 %
Q58D55 BXGT015223 Beta-galactosidase reviewed - GLB1 IC50 '=' 560000 nM
Q2KHZ8 BXGT014115 Lysosomal acid glucosylceramidase reviewed - GBA Inhibition '<' 50 %
Q5DUH8 BXGT015324 Alpha-galactosidase unreviewed - gal1 Inhibition '<' 50 %
P23739 BXGT008901 Sucrase-isomaltase, intestinal reviewed - Si IC50 '=' 150000 nM
Q4FZV0 BXGT014807 Beta-mannosidase reviewed - Manba Inhibition '<' 50 %
Q9H227 BXGT020447 Cytosolic beta-glucosidase reviewed Enzyme GBA3 Inhibition '<' 50 %
P04062 BXGT006140 Lysosomal acid glucosylceramidase reviewed - GBA Inhibition '<' 50 %
P23739 BXGT008901 Sucrase-isomaltase, intestinal reviewed - Si IC50 '=' 28000 nM
Q9UUZ4 BXGT021832 Alpha-galactosidase C reviewed - aglC Inhibition '<' 50 %
P16278 BXGT008213 Beta-galactosidase reviewed Enzyme GLB1 Inhibition '<' 50 %
Q02401 BXGT012651 Lactase-phlorizin hydrolase reviewed - Lct IC50 '=' 317000 nM
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF02214 Morus bombycis Morus bombycis Medicinal Plant
BXGF03024 Taxillus chinensis Taxillus chinensis Human Edible Plant
BXGF04607 Morus alba Morus alba Medicinal Plant
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease