Showing entry for Fagomine


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Compound Information
BXGC IdBXGC0050608
Compound NameFagomine
Structure
FormulaC6H13NO3
InchiKeyYZNNBIPIQWYLDM-HSUXUTPPSA-N
SMILESOC[C@H]1NCC[C@H]([C@@H]1O)O
InchiInChI=1S/C6H13NO3/c8-3-4-6(10)5(9)1-2-7-4/h4-10H,1-3H2/t4-,5-,6-/m1/s1
IUPAC(2R,3R,4R)-2-(hydroxymethyl)piperidine-3,4-diol
Molecular Weight147.09
Pubchem Id72259
Chembl IdCHEMBL108084
Targets of Information Source
DrugBank n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
Uniport Id BXGT Id Protein Name Status Protein Class Gene Groups Target Type
PDB n.a
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM Ka M-1
Binding DB 50240725
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
Uniport Id BXGT Id Protein Name Status Protein Class Gene Ki nM ic50 nM Kd nM EC50 nM
reviewed BXGT015223 Beta-galactosidase reviewed GLB1 - 38000 - -
reviewed BXGT008901 Sucrase-isomaltase, intestinal reviewed Si - 46000 - -
reviewed BXGT008901 Sucrase-isomaltase, intestinal reviewed Si - 37000 - -
reviewed BXGT008901 Sucrase-isomaltase, intestinal reviewed Si - 34000 - -
reviewed BXGT014115 Lysosomal acid glucosylceramidase reviewed GBA - 250000 - -
reviewed BXGT016460 Lysosomal alpha-glucosidase reviewed Gaa - 820000 - -
reviewed BXGT008901 Sucrase-isomaltase, intestinal reviewed Si - 460000 - -
reviewed BXGT008901 Sucrase-isomaltase, intestinal reviewed Si - 90000 - -
reviewed BXGT009851 Glycogen debranching enzyme reviewed AGL - 2100 - -
reviewed BXGT005280 Ceramide glucosyltransferase reviewed Ugcg - >10000 - -
reviewed BXGT020533 Non-lysosomal glucosylceramidase reviewed GBA2 - >1000000 - -
reviewed BXGT021111 Lysosomal alpha-glucosidase reviewed GAA - 520000 - -
reviewed BXGT017923 Neutral alpha-glucosidase C reviewed Ganc - 460000 - -
reviewed BXGT013501 Neutral alpha-glucosidase AB reviewed Enzyme GANAB - 1000000 - -
reviewed BXGT006142 Tissue alpha-L-fucosidase reviewed FUCA1 - 140000 - -
CHEMBL CHEMBL108084
Uniport Id BXGT Id Protein Name Status Protein Class Gene width="10%">Type Relation value Units
Uniport Id BXGT Id Protein Name Status Protein Class Gene Type Relation value Units
Q14697 BXGT013501 Neutral alpha-glucosidase AB reviewed Enzyme GANAB IC50 - - -
O88693 BXGT005280 Ceramide glucosyltransferase reviewed - Ugcg Inhibition - - -
P04062 BXGT006140 Lysosomal acid glucosylceramidase reviewed - GBA Activity - - -
Q6P7A9 BXGT016460 Lysosomal alpha-glucosidase reviewed - Gaa IC50 '=' 820000 nM
Q58D55 BXGT015223 Beta-galactosidase reviewed - GLB1 IC50 '=' 38000 nM
P23739 BXGT008901 Sucrase-isomaltase, intestinal reviewed - Si IC50 '=' 46000 nM
Q2KHZ8 BXGT014115 Lysosomal acid glucosylceramidase reviewed - GBA IC50 '=' 250000 nM
P10253 BXGT007550 Lysosomal alpha-glucosidase reviewed Enzyme GAA Inhibition '<' 50 %
P23739 BXGT008901 Sucrase-isomaltase, intestinal reviewed - Si IC50 '=' 90000 nM
Q14697 BXGT013501 Neutral alpha-glucosidase AB reviewed Enzyme GANAB Activity - - -
O70282 BXGT005062 Trehalase unreviewed - IC50 - - -
Q58D55 BXGT015223 Beta-galactosidase reviewed - GLB1 IC50 - - -
Q14697 BXGT013501 Neutral alpha-glucosidase AB reviewed Enzyme GANAB IC50 '=' 1000000 nM
P10482 BXGT007574 Beta-glucosidase A reviewed - bglA IC50 - - -
P04066 BXGT006142 Tissue alpha-L-fucosidase reviewed - FUCA1 IC50 '=' 140000 nM
D3ZUM4 BXGT002920 Beta-galactosidase unreviewed - Glb1 IC50 '=' 15000 nM
Q9MYM4 BXGT021111 Lysosomal alpha-glucosidase reviewed - GAA IC50 '=' 520000 nM
P04062 BXGT006140 Lysosomal acid glucosylceramidase reviewed - GBA Inhibition '<' 50 %
P35574 BXGT009851 Glycogen debranching enzyme reviewed - AGL IC50 '=' 2100 nM
Q8BVW0 BXGT017923 Neutral alpha-glucosidase C reviewed - Ganc IC50 '=' 460000 nM
D3ZUM4 BXGT002920 Beta-galactosidase unreviewed - Glb1 IC50 - - -
Q9HCG7 BXGT020533 Non-lysosomal glucosylceramidase reviewed - GBA2 IC50 '>' 1000000 nM
P23739 BXGT008901 Sucrase-isomaltase, intestinal reviewed - Si IC50 '=' 37000 nM
P23739 BXGT008901 Sucrase-isomaltase, intestinal reviewed - Si IC50 '=' 460000 nM
Q6P7A9 BXGT016460 Lysosomal alpha-glucosidase reviewed - Gaa IC50 - - -
Q02401 BXGT012651 Lactase-phlorizin hydrolase reviewed - Lct Inhibition '<' 50 %
Q2KIM0 BXGT014117 Tissue alpha-L-fucosidase reviewed - FUCA1 Inhibition '<' 50 %
P23739 BXGT008901 Sucrase-isomaltase, intestinal reviewed - Si IC50 '=' 34000 nM
O88693 BXGT005280 Ceramide glucosyltransferase reviewed - Ugcg IC50 '>' 10000 nM
Foods  containing  the  compound
Foods
BXGF Id Food Name Scientific Name Food Group
BXGF Id Food Name Scientific Name Food Group
BXGF00845 Castanospermum australe Castanospermum australe Vegetables
BXGF00916 Erythrina speciosa Erythrina speciosa Others
BXGF00978 Prunus prostrata Prunus prostrata Medicinal Plant
BXGF02214 Morus bombycis Morus bombycis Medicinal Plant
BXGF02560 Richteria pyrethroides Richteria pyrethroides Others
BXGF03204 Xanthocercis zambesiaca Xanthocercis zambesiaca Others
BXGF04099 Piper divaricatum Piper divaricatum Others
BXGF04110 Helichrysum drakensbergense Helichrysum drakensbergense Others
BXGF04167 Santolina pectinata Santolina pectinata Others
BXGF04185 Prosopis africana Prosopis africana Medicinal Plant
BXGF04364 Commiphora sphaerocarpa Commiphora sphaerocarpa Others
BXGF04374 Satureja vulgaris Satureja vulgaris Others
BXGF04607 Morus alba Morus alba Medicinal Plant
BXGF05068 aglaonema treubii aglaonema treubii Others
The  compound-realted  diseases
Diseases
BXGD Id Disease Name CUI Disease Id Disease Class Name Number of targets?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease