acompound

Showing entry for (2S,4S)-4-Hydroxyglutamic Acid

　　　　　　　　　　　　　　　

General Compound Information
BXGC Id	BXGC0052372
Compound Name	(2S,4S)-4-Hydroxyglutamic Acid
Structure
Formula	C5H9NO5
InchiKey	HBDWQSHEVMSFGY-HRFVKAFMSA-N
SMILES	OC(=O)[C@H](C[C@@H](C(=O)O)O)N
Inchi	InChI=1S/C5H9NO5/c6-2(4(8)9)1-3(7)5(10)11/h2-3,7H,1,6H2,(H,8,9)(H,10,11)/t2-,3-/m0/s1
IUPAC	(2S,4S)-2-amino-4-hydroxypentanedioic acid
Molecular Weight	163.05
Pubchem Id	192790
Chembl Id	CHEMBL197110

Targets of Information Source

DrugBank

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Groups	Target Type

PDB

n.a

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	Ka M-1

Binding DB

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Ki nM	ic50 nM	Kd nM	EC50 nM
reviewed	BXGT009539	Metabotropic glutamate receptor 2	reviewed		Grm2	-	-	-	137000
reviewed	BXGT008861	Metabotropic glutamate receptor 1	reviewed		Grm1	-	-	-	11000
reviewed	BXGT011675	Metabotropic glutamate receptor 8	reviewed		Grm8	-	-	-	53000

CHEMBL

Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	width="10%">Type	Relation	value	Units
Uniport Id	BXGT Id	Protein Name	Status	Protein Class	Gene	Type	Relation	value	Units
P43005	BXGT010349	Excitatory amino acid transporter 3	reviewed	Transporter	SLC1A1	Km	'='	81000	nM
P43003	BXGT010347	Excitatory amino acid transporter 1	reviewed	Transporter	SLC1A3	pKm	'='	4	-
P43004	BXGT010348	Excitatory amino acid transporter 2	reviewed	Transporter	SLC1A2	pKm	'='	4	-
P43004	BXGT010348	Excitatory amino acid transporter 2	reviewed	Transporter	SLC1A2	Km	'='	67000	nM
P31421	BXGT009539	Metabotropic glutamate receptor 2	reviewed	-	Grm2	Rmax	'='	60	mM
P70579	BXGT011675	Metabotropic glutamate receptor 8	reviewed	-	Grm8	Rmax	'='	94	mM
P31421	BXGT009539	Metabotropic glutamate receptor 2	reviewed	-	Grm2	EC50	'='	137000	nM
P23385	BXGT008861	Metabotropic glutamate receptor 1	reviewed	-	Grm1	Rmax	'='	95	mM
P23385	BXGT008861	Metabotropic glutamate receptor 1	reviewed	-	Grm1	EC50	'='	11000	nM
P70579	BXGT011675	Metabotropic glutamate receptor 8	reviewed	-	Grm8	EC50	'='	53000	nM
P43003	BXGT010347	Excitatory amino acid transporter 1	reviewed	Transporter	SLC1A3	Km	'='	140000	nM
P43005	BXGT010349	Excitatory amino acid transporter 3	reviewed	Transporter	SLC1A1	pKm	'='	4	-

Foods containing the compound

Foods

BXGF Id	Food Name	Scientific Name	Food Group
BXGF Id	Food Name	Scientific Name	Food Group
BXGF02548	Hemerocallis fulva	Hemerocallis fulva	Medicinal Plant

The compound-realted diseases

Diseases

BXGD Id	Disease Name	CUI Disease Id	Disease Class Name	Number of targets^{?Number of targets related to compound connecting disease, higher numbers indicate the compound is more associated with the disease}