adisease

Showing entry for Gingivitis

General Disease Information
BXGD Id	BXGD001122
Disease Name	Gingivitis
Disease CUI Id	C0017574
MeSH Codes	C01 C07
Disease Class Name	Infections; Stomatognathic Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id	HP:0000152
Human Phenotype Ontology Term	Abnormality of head or neck
Disease Ontology Id	DOID:7
Disease Ontology Class Name	disease of anatomical entity
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O00206	BXGT003894	Toll-like receptor 4	7099	reviewed
O14788	BXGT004100	Tumor necrosis factor ligand superfamily member 11	8600	reviewed	Signaling
O60603	BXGT004887	Toll-like receptor 2	7097	reviewed
P00747	BXGT005639	Plasminogen	5340	reviewed	Enzyme
P01034	BXGT005721	Cystatin-C	1471	reviewed
P01137	BXGT005737	Transforming growth factor beta-1 proprotein	7040	reviewed	Signaling
P01215	BXGT005743	Glycoprotein hormones alpha chain	1081	reviewed
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01579	BXGT005770	Interferon gamma	3458	reviewed
P01583	BXGT005771	Interleukin-1 alpha	3552	reviewed
P01584	BXGT005772	Interleukin-1 beta	3553	reviewed
P01589	BXGT005773	Interleukin-2 receptor subunit alpha	3559	reviewed	Receptor
P02461	BXGT005880	Collagen alpha-1(III) chain	1281	reviewed
P02538	BXGT005888	Keratin, type II cytoskeletal 6A	3853	reviewed
P02741	BXGT005936	C-reactive protein	1401	reviewed
P02765	BXGT005952	Alpha-2-HS-glycoprotein	197	reviewed	Enzyme modulator
P03372	BXGT006059	Estrogen receptor	2099	reviewed	Nuclear receptor
P03956	BXGT006120	Interstitial collagenase	4312	reviewed	Enzyme
P04083	BXGT006147	Annexin A1	301	reviewed
P04839	BXGT006273	Cytochrome b-245 heavy chain	1536	reviewed	Ion channel
P05107	BXGT006316	Integrin beta-2	3689	reviewed	Receptor
P05164	BXGT006333	Myeloperoxidase	4353	reviewed	Enzyme
P05231	BXGT006345	Interleukin-6	3569	reviewed
P06702	BXGT006476	Protein S100-A9	6280	reviewed	Calcium-binding protein
P07225	BXGT006572	Vitamin K-dependent protein S	5627	reviewed
P08246	BXGT006756	Neutrophil elastase	1991	reviewed	Enzyme
P09429	BXGT006889	High mobility group protein B1	3146	reviewed	Nucleic acid binding
P0DN79	BXGT007511	Cystathionine beta-synthase-like protein	875	reviewed
P10147	BXGT007543	C-C motif chemokine 3	6348	reviewed	Signaling
P10809	BXGT007617	60 kDa heat shock protein, mitochondrial	3329	reviewed
P11166	BXGT007661	Solute carrier family 2, facilitated glucose transporter member 1	6513	reviewed	Transporter
P11215	BXGT007672	Integrin alpha-M	3684	reviewed
P11473	BXGT007709	Vitamin D3 receptor	7421	reviewed	Nuclear receptor
P13500	BXGT007916	C-C motif chemokine 2	6347	reviewed	Signaling
P14210	BXGT007994	Hepatocyte growth factor	3082	reviewed	Enzyme
P14598	BXGT008024	Neutrophil cytosol factor 1	653361	reviewed
P14780	BXGT008053	Matrix metalloproteinase-9	4318	reviewed	Enzyme
P15328	BXGT008108	Folate receptor alpha	2348	reviewed
P15692	BXGT008147	Vascular endothelial growth factor A	7422	reviewed	Signaling
P16581	BXGT008245	E-selectin	6401	reviewed
P19021	BXGT008449	Peptidyl-glycine alpha-amidating monooxygenase	5066	reviewed	Enzyme
P20701	BXGT008591	Integrin alpha-L	3683	reviewed
P21579	BXGT008665	Synaptotagmin-1	6857	reviewed	Transporter
P21980	BXGT008715	Protein-glutamine gamma-glutamyltransferase 2	7052	reviewed	Enzyme
P22894	BXGT008815	Neutrophil collagenase	4317	reviewed	Enzyme
P29034	BXGT009309	Protein S100-A2	6273	reviewed	Calcium-binding protein
P29466	BXGT009349	Caspase-1	834	reviewed	Enzyme
P29965	BXGT009388	CD40 ligand	959	reviewed	Signaling
P30556	BXGT009441	Type-1 angiotensin II receptor	185	reviewed	G-protein coupled receptor
P35228	BXGT009800	Nitric oxide synthase, inducible	4843	reviewed
P35354	BXGT009816	Prostaglandin G/H synthase 2	5743	reviewed	Enzyme
P35520	BXGT009842	Cystathionine beta-synthase	875	reviewed
P35869	BXGT009877	Aryl hydrocarbon receptor	196	reviewed	Transcription factor
P40763	BXGT010202	Signal transducer and activator of transcription 3	6774	reviewed	Nucleic acid binding
P45452	BXGT010462	Collagenase 3	4322	reviewed	Enzyme
P49902	BXGT010758	Cytosolic purine 5'-nucleotidase	22978	reviewed	Enzyme
P51679	BXGT010877	C-C chemokine receptor type 4	1233	reviewed	G-protein coupled receptor
P51684	BXGT010880	C-C chemokine receptor type 6	1235	reviewed	G-protein coupled receptor
P53634	BXGT011007	Dipeptidyl peptidase 1	1075	reviewed	Enzyme
P60022	BXGT011285	Beta-defensin 1	1672	reviewed
P61011	BXGT011346	Signal recognition particle 54 kDa protein	6729	reviewed	Nucleic acid binding
P61626	BXGT011382	Lysozyme C	4069	reviewed
P78325	BXGT011832	Disintegrin and metalloproteinase domain-containing protein 8	101	reviewed	Enzyme
P78536	BXGT011847	Disintegrin and metalloproteinase domain-containing protein 17	6868	reviewed
P80511	BXGT011914	Protein S100-A12	6283	reviewed	Calcium-binding protein
Q01968	BXGT012626	Inositol polyphosphate 5-phosphatase OCRL-1	4952	reviewed	Enzyme
Q04206	BXGT012754	Transcription factor p65	5970	reviewed	Transcription factor
Q13085	BXGT013309	Acetyl-CoA carboxylase 1	31	reviewed
Q14116	BXGT013442	Interleukin-18	3606	reviewed
Q15078	BXGT013534	Cyclin-dependent kinase 5 activator 1	8851	reviewed	Enzyme modulator
Q15080	BXGT013535	Neutrophil cytosol factor 4	4689	reviewed
Q15485	BXGT013574	Ficolin-2	2220	reviewed	Signaling
Q16665	BXGT013653	Hypoxia-inducible factor 1-alpha	3091	reviewed	Transcription factor
Q6NYC1	BXGT016436	Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6	23210	reviewed	Receptor
Q6ZMJ4	BXGT016628	Interleukin-34	146433	reviewed
Q92743	BXGT019368	Serine protease HTRA1	5654	reviewed	Enzyme
Q96AZ6	BXGT019621	Interferon-stimulated gene 20 kDa protein	3669	reviewed
Q96P20	BXGT019704	NACHT, LRR and PYD domains-containing protein 3	114548	reviewed
Q96PD4	BXGT019705	Interleukin-17F	112744	reviewed
Q9BQ65	BXGT020107	U6 snRNA phosphodiesterase	79650	reviewed
Q9BZS1	BXGT020203	Forkhead box protein P3	50943	reviewed
Q9H4A3	BXGT020473	Serine/threonine-protein kinase WNK1	65125	reviewed	Kinase
Q9NR12	BXGT021174	PDZ and LIM domain protein 7	9260	reviewed	Cellular structure
Q9NRW3	BXGT021195	DNA dC->dU-editing enzyme APOBEC-3C	27350	reviewed	Enzyme
Q9UBV7	BXGT021665	Beta-1,4-galactosyltransferase 7	11285	reviewed
Q9UM07	BXGT021771	Protein-arginine deiminase type-4	23569	reviewed
Q9Y2J8	BXGT022237	Protein-arginine deiminase type-2	11240	reviewed
O60502	BXGT023392	Protein O-GlcNAcase	10724	reviewed
Q16552	BXGT023419	Interleukin-17A	3605	reviewed
Q9BQQ3	BXGT024065	Golgi reassembly-stacking protein 1	64689	reviewed
Q695T7	BXGT024794	Sodium-dependent neutral amino acid transporter B(0)AT1	340024	reviewed
P20809	BXGT025043	Interleukin-11	3589	reviewed
Q9UQE7	BXGT025899	Structural maintenance of chromosomes protein 3	9126	reviewed
P00403	BXGT026137	Cytochrome c oxidase subunit 2	4513	reviewed	Enzyme

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}