Showing entry for Heart valve disease


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD001237
Disease NameHeart valve disease
Disease CUI IdC0018824
MeSH Codes C14  
Disease Class NameCardiovascular Diseases
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id HP:0001626  
Human Phenotype Ontology TermAbnormality of the cardiovascular system
Disease Ontology Id DOID:7  
Disease Ontology Class Namedisease of anatomical entity
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00180 BXGT003888 Potassium channel subfamily K member 1 3775 reviewed Ion channel
O60674 BXGT004892 Tyrosine-protein kinase JAK2 3717 reviewed Kinase
P00734 BXGT005630 Prothrombin 2147 reviewed Enzyme
P00742 BXGT005636 Coagulation factor X 2159 reviewed Enzyme
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P01270 BXGT005746 Parathyroid hormone 5741 reviewed
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P02452 BXGT005878 Collagen alpha-1(I) chain 1277 reviewed
P02649 BXGT005909 Apolipoprotein E 348 reviewed
P02741 BXGT005936 C-reactive protein 1401 reviewed
P02751 BXGT005943 Fibronectin 2335 reviewed Signaling
P02818 BXGT005969 Osteocalcin 632 reviewed
P04275 BXGT006180 von Willebrand factor 7450 reviewed Enzyme modulator
P05107 BXGT006316 Integrin beta-2 3689 reviewed Receptor
P07101 BXGT006547 Tyrosine 3-monooxygenase 7054 reviewed
P11362 BXGT007693 Fibroblast growth factor receptor 1 2260 reviewed Kinase
P12314 BXGT007798 High affinity immunoglobulin gamma Fc receptor I 2209 reviewed Cell adhesion
P12643 BXGT007830 Bone morphogenetic protein 2 650 reviewed Signaling
P12821 BXGT007849 Angiotensin-converting enzyme 1636 reviewed Enzyme
P13500 BXGT007916 C-C motif chemokine 2 6347 reviewed Signaling
P13671 BXGT007941 Complement component C6 729 reviewed
P14324 BXGT008005 Farnesyl pyrophosphate synthase 2224 reviewed Enzyme
P17655 BXGT008325 Calpain-2 catalytic subunit 824 reviewed Enzyme
P21333 BXGT008638 Filamin-A 2316 reviewed
P22304 BXGT008752 Iduronate 2-sulfatase 3423 reviewed
P27169 BXGT009161 Serum paraoxonase/arylesterase 1 5444 reviewed
P27797 BXGT009206 Calreticulin 811 reviewed Calcium-binding protein
P28222 BXGT009238 5-hydroxytryptamine receptor 1B 3351 reviewed G-protein coupled receptor
P29350 BXGT009335 Tyrosine-protein phosphatase non-receptor type 6 5777 reviewed
P29474 BXGT009352 Nitric oxide synthase, endothelial 4846 reviewed
P30988 BXGT009491 Calcitonin receptor 799 reviewed G-protein coupled receptor
P31645 BXGT009558 Sodium-dependent serotonin transporter 6532 reviewed Transporter
P35414 BXGT009829 Apelin receptor 187 reviewed G-protein coupled receptor
P39060 BXGT010088 Collagen alpha-1(XVIII) chain 80781 reviewed
P41595 BXGT010267 5-hydroxytryptamine receptor 2B 3357 reviewed G-protein coupled receptor
P42574 BXGT010317 Caspase-3 836 reviewed Enzyme
P46531 BXGT010526 Neurogenic locus notch homolog protein 1 4851 reviewed
P48029 BXGT010606 Sodium- and chloride-dependent creatine transporter 1 6535 reviewed Transporter
P80188 BXGT011882 Neutrophil gelatinase-associated lipocalin 3934 reviewed Enzyme
Q13085 BXGT013309 Acetyl-CoA carboxylase 1 31 reviewed
Q14116 BXGT013442 Interleukin-18 3606 reviewed
Q15063 BXGT013531 Periostin 10631 reviewed Signaling
Q92736 BXGT019367 Ryanodine receptor 2 6262 reviewed Ion channel
Q96HC4 BXGT019671 PDZ and LIM domain protein 5 10611 reviewed Cellular structure
Q9BQB6 BXGT020108 Vitamin K epoxide reductase complex subunit 1 79001 reviewed Enzyme
Q9UL51 BXGT021754 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 610 reviewed Ion channel
Q9Y572 BXGT022289 Receptor-interacting serine/threonine-protein kinase 3 11035 reviewed Kinase
Q16552 BXGT023419 Interleukin-17A 3605 reviewed
P08123 BXGT024477 Collagen alpha-2(I) chain 1278 reviewed
P19474 BXGT025520 E3 ubiquitin-protein ligase TRIM21 6737 reviewed
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease