Showing entry for Acute myelomonocytic leukemia


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD001663
Disease NameAcute myelomonocytic leukemia
Disease CUI IdC0023479
MeSH Codes C04  
Disease Class NameNeoplasms
Semantic TypeNeoplastic Process
Human Phenotype Ontology Id HP:0002715   HP:0002664   HP:0001871  
Human Phenotype Ontology TermAbnormality of the immune system; Neoplasm; Abnormality of blood and blood-forming tissues
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
P00374 BXGT005520 Dihydrofolate reductase 1719 reviewed Enzyme
P00519 BXGT005570 Tyrosine-protein kinase ABL1 25 reviewed Kinase
P01111 BXGT005731 GTPase NRas 4893 reviewed Enzyme modulator
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P02751 BXGT005943 Fibronectin 2335 reviewed Signaling
P02786 BXGT005961 Transferrin receptor protein 1 7037 reviewed Enzyme
P04637 BXGT006243 Cellular tumor antigen p53 7157 reviewed Transcription factor
P04792 BXGT006264 Heat shock protein beta-1 3315 reviewed
P04839 BXGT006273 Cytochrome b-245 heavy chain 1536 reviewed Ion channel
P05164 BXGT006333 Myeloperoxidase 4353 reviewed Enzyme
P06730 BXGT006487 Eukaryotic translation initiation factor 4E 1977 reviewed Nucleic acid binding
P06748 BXGT006497 Nucleophosmin 4869 reviewed Chaperone
P07101 BXGT006547 Tyrosine 3-monooxygenase 7054 reviewed
P07333 BXGT006602 Macrophage colony-stimulating factor 1 receptor 1436 reviewed Kinase
P07949 BXGT006703 Proto-oncogene tyrosine-protein kinase receptor Ret 5979 reviewed Kinase
P10721 BXGT007605 Mast/stem cell growth factor receptor Kit 3815 reviewed Kinase
P11215 BXGT007672 Integrin alpha-M 3684 reviewed
P11274 BXGT007681 Breakpoint cluster region protein 613 reviewed Enzyme modulator
P11362 BXGT007693 Fibroblast growth factor receptor 1 2260 reviewed Kinase
P12314 BXGT007798 High affinity immunoglobulin gamma Fc receptor I 2209 reviewed Cell adhesion
P14598 BXGT008024 Neutrophil cytosol factor 1 653361 reviewed
P14780 BXGT008053 Matrix metalloproteinase-9 4318 reviewed Enzyme
P14921 BXGT008068 Protein C-ets-1 2113 reviewed Transcription factor
P15941 BXGT008176 Mucin-1 4582 reviewed
P20309 BXGT008562 Muscarinic acetylcholine receptor M3 1131 reviewed G-protein coupled receptor
P21333 BXGT008638 Filamin-A 2316 reviewed
P22083 BXGT008727 Alpha-(1,3)-fucosyltransferase 4 2526 reviewed Enzyme
P22303 BXGT008751 Acetylcholinesterase 43 reviewed Enzyme
P28068 BXGT009229 HLA class II histocompatibility antigen, DM beta chain 3109 reviewed Immune response
P28482 BXGT009263 Mitogen-activated protein kinase 1 5594 reviewed Kinase
P28907 BXGT009301 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 952 reviewed Enzyme
P30281 BXGT009416 G1/S-specific cyclin-D3 896 reviewed Enzyme modulator
P30304 BXGT009418 M-phase inducer phosphatase 1 993 reviewed Enzyme
P35869 BXGT009877 Aryl hydrocarbon receptor 196 reviewed Transcription factor
P36888 BXGT009938 Receptor-type tyrosine-protein kinase FLT3 2322 reviewed Kinase
P46531 BXGT010526 Neurogenic locus notch homolog protein 1 4851 reviewed
P49792 BXGT010743 E3 SUMO-protein ligase RanBP2 5903 reviewed Enzyme modulator
P61073 BXGT011352 C-X-C chemokine receptor type 4 7852 reviewed G-protein coupled receptor
Q00987 BXGT012559 E3 ubiquitin-protein ligase Mdm2 4193 reviewed Nucleic acid binding
Q01196 BXGT012575 Runt-related transcription factor 1 861 reviewed Transcription factor
Q03164 BXGT012700 Histone-lysine N-methyltransferase 2A 4297 reviewed
Q06124 BXGT012856 Tyrosine-protein phosphatase non-receptor type 11 5781 reviewed
Q07820 BXGT012942 Induced myeloid leukemia cell differentiation protein Mcl-1 4170 reviewed Signaling
Q13315 BXGT013339 Serine-protein kinase ATM 472 reviewed Kinase
Q13951 BXGT013407 Core-binding factor subunit beta 865 reviewed
Q14141 BXGT013447 Septin-6 23157 reviewed Enzyme modulator
Q14289 BXGT013459 Protein-tyrosine kinase 2-beta 2185 reviewed Kinase
Q14542 BXGT013482 Equilibrative nucleoside transporter 2 3177 reviewed Transporter
Q15118 BXGT013540 [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial 5163 reviewed Kinase
Q15596 BXGT013582 Nuclear receptor coactivator 2 10499 reviewed Enzyme
Q15848 BXGT013609 Adiponectin 9370 reviewed
Q8NG31 BXGT018565 Kinetochore scaffold 1 57082 reviewed
Q92793 BXGT019374 CREB-binding protein 1387 reviewed
Q92794 BXGT019375 Histone acetyltransferase KAT6A 7994 reviewed Enzyme
Q9UHD8 BXGT021698 Septin-9 10801 reviewed Enzyme modulator
Q9UM73 BXGT021773 ALK tyrosine kinase receptor 238 reviewed Kinase
Q9Y6K1 BXGT022331 DNA (cytosine-5)-methyltransferase 3A 1788 reviewed
Q96L73 BXGT024676 Histone-lysine N-methyltransferase, H3 lysine-36 specific 64324 reviewed Epigenetic regulator
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease