Showing entry for Mitral Valve Stenosis


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD001897
Disease NameMitral Valve Stenosis
Disease CUI IdC0026269
MeSH Codes C14  
Disease Class NameCardiovascular Diseases
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id HP:0001626  
Human Phenotype Ontology TermAbnormality of the cardiovascular system
Disease Ontology Id DOID:7  
Disease Ontology Class Namedisease of anatomical entity
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00206 BXGT003894 Toll-like receptor 4 7099 reviewed
O00222 BXGT003899 Metabotropic glutamate receptor 8 2918 reviewed G-protein coupled receptor
O14788 BXGT004100 Tumor necrosis factor ligand superfamily member 11 8600 reviewed Signaling
O14994 BXGT004120 Synapsin-3 8224 reviewed Cellular structure
O15350 BXGT004154 Tumor protein p73 7161 reviewed Transcription factor
O95150 BXGT005351 Tumor necrosis factor ligand superfamily member 15 9966 reviewed Signaling
O95255 BXGT005363 Multidrug resistance-associated protein 6 368 reviewed Transporter
P00441 BXGT005540 Superoxide dismutase [Cu-Zn] 6647 reviewed Enzyme
P00709 BXGT005621 Alpha-lactalbumin 3906 reviewed
P00750 BXGT005642 Tissue-type plasminogen activator 5327 reviewed Enzyme
P01009 BXGT005714 Alpha-1-antitrypsin 5265 reviewed Enzyme modulator
P01024 BXGT005719 Complement C3 718 reviewed Enzyme modulator
P01042 BXGT005722 Kininogen-1 3827 reviewed Enzyme modulator
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P01236 BXGT005744 Prolactin 5617 reviewed Signaling
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01574 BXGT005768 Interferon beta 3456 reviewed
P01579 BXGT005770 Interferon gamma 3458 reviewed
P01583 BXGT005771 Interleukin-1 alpha 3552 reviewed
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P01589 BXGT005773 Interleukin-2 receptor subunit alpha 3559 reviewed Receptor
P01909 BXGT005815 HLA class II histocompatibility antigen, DQ alpha 1 chain 3117 reviewed Immune response
P01911 BXGT005816 HLA class II histocompatibility antigen, DRB1-15 beta chain 3123 reviewed Immune response
P02144 BXGT005853 Myoglobin 4151 reviewed
P02458 BXGT005879 Collagen alpha-1(II) chain 1280 reviewed
P02649 BXGT005909 Apolipoprotein E 348 reviewed
P02741 BXGT005936 C-reactive protein 1401 reviewed
P02768 BXGT005955 Serum albumin 213 reviewed Transporter
P04040 BXGT006132 Catalase 847 reviewed Enzyme
P04062 BXGT006140 Lysosomal acid glucosylceramidase 2629 reviewed
P04440 BXGT006216 HLA class II histocompatibility antigen, DP beta 1 chain 3115 reviewed Immune response
P05121 BXGT006320 Plasminogen activator inhibitor 1 5054 reviewed Enzyme modulator
P05164 BXGT006333 Myeloperoxidase 4353 reviewed Enzyme
P05231 BXGT006345 Interleukin-6 3569 reviewed
P07101 BXGT006547 Tyrosine 3-monooxygenase 7054 reviewed
P07550 BXGT006636 Beta-2 adrenergic receptor 154 reviewed G-protein coupled receptor
P08253 BXGT006757 72 kDa type IV collagenase 4313 reviewed Enzyme
P08254 BXGT006758 Stromelysin-1 4314 reviewed Enzyme
P08700 BXGT006816 Interleukin-3 3562 reviewed
P09601 BXGT006909 Heme oxygenase 1 3162 reviewed
P10600 BXGT007584 Transforming growth factor beta-3 proprotein 7043 reviewed Signaling
P10644 BXGT007597 cAMP-dependent protein kinase type I-alpha regulatory subunit 5573 reviewed
P11308 BXGT007684 Transcriptional regulator ERG 2078 reviewed Transcription factor
P11473 BXGT007709 Vitamin D3 receptor 7421 reviewed Nuclear receptor
P12821 BXGT007849 Angiotensin-converting enzyme 1636 reviewed Enzyme
P12955 BXGT007865 Xaa-Pro dipeptidase 5184 reviewed Enzyme
P13500 BXGT007916 C-C motif chemokine 2 6347 reviewed Signaling
P13612 BXGT007928 Integrin alpha-4 3676 reviewed
P14174 BXGT007991 Macrophage migration inhibitory factor 4282 reviewed
P14672 BXGT008037 Solute carrier family 2, facilitated glucose transporter member 4 6517 reviewed Transporter
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P15813 BXGT008158 Antigen-presenting glycoprotein CD1d 912 reviewed
P17706 BXGT008330 Tyrosine-protein phosphatase non-receptor type 2 5771 reviewed
P19438 BXGT008480 Tumor necrosis factor receptor superfamily member 1A 7132 reviewed
P19838 BXGT008526 Nuclear factor NF-kappa-B p105 subunit 4790 reviewed Transcription factor
P20591 BXGT008586 Interferon-induced GTP-binding protein Mx1 4599 reviewed Enzyme modulator
P21964 BXGT008714 Catechol O-methyltransferase 1312 reviewed Enzyme
P23560 BXGT008883 Brain-derived neurotrophic factor 627 reviewed Signaling
P27169 BXGT009161 Serum paraoxonase/arylesterase 1 5444 reviewed
P27487 BXGT009187 Dipeptidyl peptidase 4 1803 reviewed Enzyme
P28072 BXGT009231 Proteasome subunit beta type-6 5694 reviewed
P28482 BXGT009263 Mitogen-activated protein kinase 1 5594 reviewed Kinase
P29323 BXGT009334 Ephrin type-B receptor 2 2048 reviewed Kinase
P35555 BXGT009845 Fibrillin-1 2200 reviewed Calcium-binding protein
P36222 BXGT009914 Chitinase-3-like protein 1 1116 reviewed
P37840 BXGT010015 Alpha-synuclein 6622 reviewed Transporter
P40189 BXGT010164 Interleukin-6 receptor subunit beta 3572 reviewed Signaling
P46531 BXGT010526 Neurogenic locus notch homolog protein 1 4851 reviewed
P46663 BXGT010531 B1 bradykinin receptor 623 reviewed G-protein coupled receptor
P48551 BXGT010645 Interferon alpha/beta receptor 2 3455 reviewed Receptor
P49888 BXGT010756 Estrogen sulfotransferase 6783 reviewed
P51681 BXGT010878 C-C chemokine receptor type 5 1234 reviewed G-protein coupled receptor
P52952 BXGT010966 Homeobox protein Nkx-2.5 1482 reviewed Transcription factor
P61769 BXGT011383 Beta-2-microglobulin 567 reviewed Immune response
P78556 BXGT011849 C-C motif chemokine 20 6364 reviewed Signaling
Q01538 BXGT012597 Myelin transcription factor 1 4661 reviewed Transcription factor
Q04721 BXGT012777 Neurogenic locus notch homolog protein 2 4853 reviewed
Q12918 BXGT013280 Killer cell lectin-like receptor subfamily B member 1 3820 reviewed
Q13393 BXGT013346 Phospholipase D1 5337 reviewed
Q14116 BXGT013442 Interleukin-18 3606 reviewed
Q14833 BXGT013508 Metabotropic glutamate receptor 4 2914 reviewed G-protein coupled receptor
Q15109 BXGT013537 Advanced glycosylation end product-specific receptor 177 reviewed Receptor
Q15848 BXGT013609 Adiponectin 9370 reviewed
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 4780 reviewed Enzyme
Q30154 BXGT014296 HLA class II histocompatibility antigen, DR beta 5 chain 3127 reviewed Immune response
Q6VVX0 BXGT016585 Vitamin D 25-hydroxylase 120227 reviewed
Q8TDQ0 BXGT018810 Hepatitis A virus cellular receptor 2 84868 reviewed
Q8TDS4 BXGT018812 Hydroxycarboxylic acid receptor 2 338442 reviewed
Q96AZ6 BXGT019621 Interferon-stimulated gene 20 kDa protein 3669 reviewed
Q96EB6 BXGT019646 NAD-dependent protein deacetylase sirtuin-1 23411 reviewed Epigenetic regulator
Q96IY4 BXGT019678 Carboxypeptidase B2 1361 reviewed Enzyme
Q96RI1 BXGT019727 Bile acid receptor 9971 reviewed Nuclear receptor
Q99707 BXGT019952 Methionine synthase 4548 reviewed
Q9BZS1 BXGT020203 Forkhead box protein P3 50943 reviewed
Q9GZX6 BXGT020428 Interleukin-22 50616 reviewed
Q16552 BXGT023419 Interleukin-17A 3605 reviewed
P29590 BXGT024350 Protein PML 5371 reviewed
Q969H8 BXGT025606 Myeloid-derived growth factor 56005 reviewed
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease