adisease

Showing entry for Otosclerosis

General Disease Information
BXGD Id	BXGD002180
Disease Name	Otosclerosis
Disease CUI Id	C0029899
MeSH Codes	C09
Disease Class Name	Otorhinolaryngologic Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id	HP:0000598
Human Phenotype Ontology Term	Abnormality of the ear
Disease Ontology Id	DOID:7
Disease Ontology Class Name	disease of anatomical entity
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O15123	BXGT004130	Angiopoietin-2	285	reviewed	Signaling
P00450	BXGT005544	Ceruloplasmin	1356	reviewed	Enzyme
P00797	BXGT005658	Renin	5972	reviewed	Enzyme
P01019	BXGT005717	Angiotensinogen	183	reviewed	Enzyme modulator
P01137	BXGT005737	Transforming growth factor beta-1 proprotein	7040	reviewed	Signaling
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01889	BXGT005809	HLA class I histocompatibility antigen, B-7 alpha chain	3106	reviewed
P02452	BXGT005878	Collagen alpha-1(I) chain	1277	reviewed
P02774	BXGT005959	Vitamin D-binding protein	2638	reviewed	Transporter
P05231	BXGT006345	Interleukin-6	3569	reviewed
P06756	BXGT006499	Integrin alpha-V	3685	reviewed
P08047	BXGT006720	Transcription factor Sp1	6667	reviewed	Nucleic acid binding
P09429	BXGT006889	High mobility group protein B1	3146	reviewed	Nucleic acid binding
P11473	BXGT007709	Vitamin D3 receptor	7421	reviewed	Nuclear receptor
P12643	BXGT007830	Bone morphogenetic protein 2	650	reviewed	Signaling
P12821	BXGT007849	Angiotensin-converting enzyme	1636	reviewed	Enzyme
P15529	BXGT008134	Membrane cofactor protein	4179	reviewed
P27169	BXGT009161	Serum paraoxonase/arylesterase 1	5444	reviewed
P27361	BXGT009176	Mitogen-activated protein kinase 3	5595	reviewed	Kinase
P30556	BXGT009441	Type-1 angiotensin II receptor	185	reviewed	G-protein coupled receptor
P36955	BXGT009946	Pigment epithelium-derived factor	5176	reviewed	Enzyme modulator
P41235	BXGT010241	Hepatocyte nuclear factor 4-alpha	3172	reviewed	Nuclear receptor
Q12830	BXGT013268	Nucleosome-remodeling factor subunit BPTF	2186	reviewed
P04439	BXGT022649	HLA class I histocompatibility antigen, A-3 alpha chain	3105	reviewed
P08123	BXGT024477	Collagen alpha-2(I) chain	1278	reviewed

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}