adisease

Showing entry for Pyruvate Dehydrogenase Complex Deficiency Disease

　　　　　　　　　　　　　　　　

General Disease Information
BXGD Id	BXGD002477
Disease Name	Pyruvate Dehydrogenase Complex Deficiency Disease
Disease CUI Id	C0034345
MeSH Codes	C16 C18 C10
Disease Class Name	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Nutritional and Metabolic Diseases; Nervous System Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id	DOID:0014667 DOID:630
Disease Ontology Class Name	disease of metabolism; genetic disease
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O00330	BXGT003910	Pyruvate dehydrogenase protein X component, mitochondrial	8050	reviewed	Enzyme
O43708	BXGT004617	Maleylacetoacetate isomerase	2954	reviewed
P08559	BXGT006788	Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial	5160	reviewed
P11177	BXGT007666	Pyruvate dehydrogenase E1 component subunit beta, mitochondrial	5162	reviewed
P12821	BXGT007849	Angiotensin-converting enzyme	1636	reviewed	Enzyme
P30084	BXGT009398	Enoyl-CoA hydratase, mitochondrial	1892	reviewed	Enzyme
Q16654	BXGT013650	[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial	5166	reviewed	Kinase
Q9Y234	BXGT022211	Lipoyltransferase 1, mitochondrial	51601	reviewed	Enzyme
P09622	BXGT023116	Dihydrolipoyl dehydrogenase, mitochondrial	1738	reviewed	Enzyme
Q86SQ9	BXGT025875	Dehydrodolichyl diphosphate synthase complex subunit DHDDS	79947	reviewed	Enzyme

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}