adisease

Showing entry for Localized scleroderma

General Disease Information
BXGD Id	BXGD002612
Disease Name	Localized scleroderma
Disease CUI Id	C0036420
MeSH Codes	C17
Disease Class Name	Skin and Connective Tissue Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id	DOID:7
Disease Ontology Class Name	disease of anatomical entity
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
P00519	BXGT005570	Tyrosine-protein kinase ABL1	25	reviewed	Kinase
P01137	BXGT005737	Transforming growth factor beta-1 proprotein	7040	reviewed	Signaling
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01574	BXGT005768	Interferon beta	3456	reviewed
P01579	BXGT005770	Interferon gamma	3458	reviewed
P01583	BXGT005771	Interleukin-1 alpha	3552	reviewed
P02545	BXGT005889	Prelamin-A/C	4000	reviewed
P03956	BXGT006120	Interstitial collagenase	4312	reviewed	Enzyme
P04637	BXGT006243	Cellular tumor antigen p53	7157	reviewed	Transcription factor
P05231	BXGT006345	Interleukin-6	3569	reviewed
P06756	BXGT006499	Integrin alpha-V	3685	reviewed
P08670	BXGT006810	Vimentin	7431	reviewed
P09486	BXGT006897	SPARC	6678	reviewed	Signaling
P10145	BXGT007542	Interleukin-8	3576	reviewed	Signaling
P10415	BXGT007567	Apoptosis regulator Bcl-2	596	reviewed	Signaling
P13501	BXGT007917	C-C motif chemokine 5	6352	reviewed	Signaling
P16581	BXGT008245	E-selectin	6401	reviewed
P22004	BXGT008718	Bone morphogenetic protein 6	654	reviewed	Signaling
P40763	BXGT010202	Signal transducer and activator of transcription 3	6774	reviewed	Nucleic acid binding
P49747	BXGT010732	Cartilage oligomeric matrix protein	1311	reviewed
P55774	BXGT011124	C-C motif chemokine 18	6362	reviewed	Signaling
P60568	BXGT011315	Interleukin-2	3558	reviewed
P60709	BXGT011322	Actin, cytoplasmic 1	60	reviewed	Cellular structure
Q15063	BXGT013531	Periostin	10631	reviewed	Signaling
Q01543	BXGT023137	Friend leukemia integration 1 transcription factor	2313	reviewed	Transcription factor
P08123	BXGT024477	Collagen alpha-2(I) chain	1278	reviewed

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}