adisease

Showing entry for Low Vision

General Disease Information
BXGD Id	BXGD003003
Disease Name	Low Vision
Disease CUI Id	C0042798
MeSH Codes	C23 C11 C10
Disease Class Name	Pathological Conditions, Signs and Symptoms; Eye Diseases; Nervous System Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id	HP:0000478
Human Phenotype Ontology Term	Abnormality of the eye
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
A0A024RAV5	BXGT000013	V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b	3845	unreviewed
O14773	BXGT004096	Tripeptidyl-peptidase 1	1200	reviewed	Enzyme
O14994	BXGT004120	Synapsin-3	8224	reviewed	Cellular structure
O15305	BXGT004152	Phosphomannomutase 2	5373	reviewed	Enzyme
O43617	BXGT004607	Trafficking protein particle complex subunit 3	27095	reviewed
O60313	BXGT004871	Dynamin-like 120 kDa protein, mitochondrial	4976	reviewed	Enzyme modulator
O75469	BXGT005128	Nuclear receptor subfamily 1 group I member 2	8856	reviewed	Nuclear receptor
O76039	BXGT005171	Cyclin-dependent kinase-like 5	6792	reviewed	Kinase
P00813	BXGT005667	Adenosine deaminase	100	reviewed	Enzyme
P01116	BXGT005733	GTPase KRas	3845	reviewed	Enzyme modulator
P02462	BXGT005881	Collagen alpha-1(IV) chain	1282	reviewed
P02511	BXGT005885	Alpha-crystallin B chain	1410	reviewed
P04049	BXGT006133	RAF proto-oncogene serine/threonine-protein kinase	5894	reviewed	Kinase
P04181	BXGT006165	Ornithine aminotransferase, mitochondrial	4942	reviewed	Enzyme
P05771	BXGT006384	Protein kinase C beta type	5579	reviewed	Kinase
P06850	BXGT006511	Corticoliberin	1392	reviewed	Signaling
P06865	BXGT006516	Beta-hexosaminidase subunit alpha	3073	reviewed	Enzyme
P08243	BXGT006755	Asparagine synthetase [glutamine-hydrolyzing]	440	reviewed	Enzyme
P08603	BXGT006798	Complement factor H	3075	reviewed
P09619	BXGT006911	Platelet-derived growth factor receptor beta	5159	reviewed	Kinase
P10646	BXGT007598	Tissue factor pathway inhibitor	7035	reviewed	Enzyme modulator
P10745	BXGT007608	Retinol-binding protein 3	5949	reviewed
P11308	BXGT007684	Transcriptional regulator ERG	2078	reviewed	Transcription factor
P15692	BXGT008147	Vascular endothelial growth factor A	7422	reviewed	Signaling
P17252	BXGT008294	Protein kinase C alpha type	5578	reviewed	Kinase
P25116	BXGT009025	Proteinase-activated receptor 1	2149	reviewed	G-protein coupled receptor
P27448	BXGT009183	MAP/microtubule affinity-regulating kinase 3	4140	reviewed	Kinase
P29317	BXGT009331	Ephrin type-A receptor 2	1969	reviewed	Kinase
P29965	BXGT009388	CD40 ligand	959	reviewed	Signaling
P33981	BXGT009744	Dual specificity protein kinase TTK	7272	reviewed	Kinase
P35475	BXGT009837	Alpha-L-iduronidase	3425	reviewed	Enzyme
P36955	BXGT009946	Pigment epithelium-derived factor	5176	reviewed	Enzyme modulator
P39060	BXGT010088	Collagen alpha-1(XVIII) chain	80781	reviewed
P43005	BXGT010349	Excitatory amino acid transporter 3	6505	reviewed	Transporter
P50897	BXGT010823	Palmitoyl-protein thioesterase 1	5538	reviewed	Enzyme
P51787	BXGT010889	Potassium voltage-gated channel subfamily KQT member 1	3784	reviewed	Ion channel
P52803	BXGT010958	Ephrin-A5	1946	reviewed	Signaling
P53041	BXGT010968	Serine/threonine-protein phosphatase 5	5536	reviewed
P55087	BXGT011105	Aquaporin-4	361	reviewed	Ion channel
P60709	BXGT011322	Actin, cytoplasmic 1	60	reviewed	Cellular structure
P98164	BXGT012230	Low-density lipoprotein receptor-related protein 2	4036	reviewed
Q00604	BXGT012538	Norrin	4693	reviewed
Q12866	BXGT013273	Tyrosine-protein kinase Mer	10461	reviewed	Kinase
Q13402	BXGT013348	Unconventional myosin-VIIa	4647	reviewed	Cellular structure
Q14683	BXGT013500	Structural maintenance of chromosomes protein 1A	8243	reviewed
Q15046	BXGT013527	Lysine--tRNA ligase	3735	reviewed	Enzyme
Q15582	BXGT013581	Transforming growth factor-beta-induced protein ig-h3	7045	reviewed	Signaling
Q2M385	BXGT014131	Macrophage-expressed gene 1 protein	219972	reviewed
Q5JTZ9	BXGT015458	Alanine--tRNA ligase, mitochondrial	57505	reviewed	Nucleic acid binding
Q5S007	BXGT015650	Leucine-rich repeat serine/threonine-protein kinase 2	120892	reviewed	Kinase
Q7KZI7	BXGT016990	Serine/threonine-protein kinase MARK2	2011	reviewed	Kinase
Q8N3R9	BXGT018507	MAGUK p55 subfamily member 5	64398	reviewed	Enzyme
Q92743	BXGT019368	Serine protease HTRA1	5654	reviewed	Enzyme
Q96KB5	BXGT019685	Lymphokine-activated killer T-cell-originated protein kinase	55872	reviewed	Kinase
Q99700	BXGT019949	Ataxin-2	6311	reviewed	Nucleic acid binding
Q99972	BXGT019979	Myocilin	4653	reviewed	Cellular structure
Q9H251	BXGT020449	Cadherin-23	64072	reviewed
Q9H3M7	BXGT020462	Thioredoxin-interacting protein	10628	reviewed
Q9H8P0	BXGT020497	Polyprenol reductase	79644	reviewed
Q9NYA1	BXGT021254	Sphingosine kinase 1	8877	reviewed	Kinase
Q9NZN9	BXGT021280	Aryl-hydrocarbon-interacting protein-like 1	23746	reviewed	Chaperone
Q9Y5X4	BXGT022306	Photoreceptor-specific nuclear receptor	10002	reviewed	Nuclear receptor
Q96KN7	BXGT022801	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1	57096	reviewed	Enzyme modulator
Q6P4Q7	BXGT024061	Metal transporter CNNM4	26504	reviewed
Q9BYE2	BXGT024631	Transmembrane protease serine 13	84000	reviewed	Enzyme
P51608	BXGT025073	Methyl-CpG-binding protein 2	4204	reviewed	Epigenetic regulator
Q9BV73	BXGT025119	Centrosome-associated protein CEP250	11190	reviewed	Enzyme modulator
P51798	BXGT026083	H(+)/Cl(-) exchange transporter 7	1186	reviewed	Ion channel

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}