Showing entry for Congenital diaphragmatic hernia


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD004775
Disease NameCongenital diaphragmatic hernia
Disease CUI IdC0235833
MeSH Codes C23   C16  
Disease Class NamePathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities
Semantic TypeCongenital Abnormality
Human Phenotype Ontology Id HP:0003549   HP:0003011  
Human Phenotype Ontology TermAbnormality of connective tissue; Abnormality of the musculature
Disease Ontology Id DOID:7  
Disease Ontology Class Namedisease of anatomical entity
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O15305 BXGT004152 Phosphomannomutase 2 5373 reviewed Enzyme
O15550 BXGT004179 Lysine-specific demethylase 6A 7403 reviewed Epigenetic regulator
O43854 BXGT004630 EGF-like repeat and discoidin I-like domain-containing protein 3 10085 reviewed Enzyme
O75460 BXGT005127 Serine/threonine-protein kinase/endoribonuclease IRE1 2081 reviewed Kinase
O94788 BXGT005333 Retinal dehydrogenase 2 8854 reviewed Enzyme
O96028 BXGT005417 Histone-lysine N-methyltransferase NSD2 7468 reviewed Epigenetic regulator
P00519 BXGT005570 Tyrosine-protein kinase ABL1 25 reviewed Kinase
P01019 BXGT005717 Angiotensinogen 183 reviewed Enzyme modulator
P01133 BXGT005736 Pro-epidermal growth factor 1950 reviewed
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P02452 BXGT005878 Collagen alpha-1(I) chain 1277 reviewed
P02741 BXGT005936 C-reactive protein 1401 reviewed
P02787 BXGT005962 Serotransferrin 7018 reviewed Enzyme
P03372 BXGT006059 Estrogen receptor 2099 reviewed Nuclear receptor
P04150 BXGT006154 Glucocorticoid receptor 2908 reviewed Nuclear receptor
P05181 BXGT006337 Cytochrome P450 2E1 1571 reviewed
P06213 BXGT006425 Insulin receptor 3643 reviewed Kinase
P06744 BXGT006494 Glucose-6-phosphate isomerase 2821 reviewed Enzyme
P07510 BXGT006631 Acetylcholine receptor subunit gamma 1146 reviewed Ion channel
P08069 BXGT006723 Insulin-like growth factor 1 receptor 3480 reviewed Kinase
P08253 BXGT006757 72 kDa type IV collagenase 4313 reviewed Enzyme
P09488 BXGT006899 Glutathione S-transferase Mu 1 2944 reviewed
P10826 BXGT007622 Retinoic acid receptor beta 5915 reviewed Nuclear receptor
P11309 BXGT007685 Serine/threonine-protein kinase pim-1 5292 reviewed Kinase
P11717 BXGT007740 Cation-independent mannose-6-phosphate receptor 3482 reviewed Receptor
P11912 BXGT007758 B-cell antigen receptor complex-associated protein alpha chain 973 reviewed Receptor
P12004 BXGT007766 Proliferating cell nuclear antigen 5111 reviewed Nucleic acid binding
P12821 BXGT007849 Angiotensin-converting enzyme 1636 reviewed Enzyme
P13500 BXGT007916 C-C motif chemokine 2 6347 reviewed Signaling
P14174 BXGT007991 Macrophage migration inhibitory factor 4282 reviewed
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P15884 BXGT008166 Transcription factor 4 6925 reviewed Transcription factor
P16070 BXGT008186 CD44 antigen 960 reviewed
P19544 BXGT008494 Wilms tumor protein 7490 reviewed Nucleic acid binding
P21333 BXGT008638 Filamin-A 2316 reviewed
P21917 BXGT008707 D(4) dopamine receptor 1815 reviewed G-protein coupled receptor
P24468 BXGT008969 COUP transcription factor 2 7026 reviewed Nuclear receptor
P24530 BXGT008975 Endothelin receptor type B 1910 reviewed G-protein coupled receptor
P25101 BXGT009018 Endothelin-1 receptor 1909 reviewed G-protein coupled receptor
P29033 BXGT009308 Gap junction beta-2 protein 2706 reviewed Cell-cell junction
P29474 BXGT009352 Nitric oxide synthase, endothelial 4846 reviewed
P30556 BXGT009441 Type-1 angiotensin II receptor 185 reviewed G-protein coupled receptor
P31040 BXGT009503 Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial 6389 reviewed Enzyme
P31749 BXGT009574 RAC-alpha serine/threonine-protein kinase 207 reviewed Kinase
P35247 BXGT009804 Pulmonary surfactant-associated protein D 6441 reviewed Surfactant
P35555 BXGT009845 Fibrillin-1 2200 reviewed Calcium-binding protein
P39019 BXGT010082 40S ribosomal protein S19 6223 reviewed Nucleic acid binding
P40763 BXGT010202 Signal transducer and activator of transcription 3 6774 reviewed Nucleic acid binding
P41180 BXGT010230 Extracellular calcium-sensing receptor 846 reviewed G-protein coupled receptor
P42345 BXGT010304 Serine/threonine-protein kinase mTOR 2475 reviewed Kinase
P43026 BXGT010351 Growth/differentiation factor 5 8200 reviewed Signaling
P49281 BXGT010689 Natural resistance-associated macrophage protein 2 4891 reviewed Transporter
P49336 BXGT010697 Cyclin-dependent kinase 8 1024 reviewed Kinase
P51532 BXGT010852 Transcription activator BRG1 6597 reviewed Epigenetic regulator
P52799 BXGT010956 Ephrin-B2 1948 reviewed Signaling
P54760 BXGT011075 Ephrin type-B receptor 4 2050 reviewed Kinase
P55789 BXGT011126 FAD-linked sulfhydryl oxidase ALR 2671 reviewed Enzyme
P56524 BXGT011176 Histone deacetylase 4 9759 reviewed Epigenetic regulator
P60709 BXGT011322 Actin, cytoplasmic 1 60 reviewed Cellular structure
P61224 BXGT011370 Ras-related protein Rap-1b 5908 reviewed Enzyme modulator
P61586 BXGT011375 Transforming protein RhoA 387 reviewed Enzyme modulator
P62736 BXGT011452 Actin, aortic smooth muscle 59 reviewed Cellular structure
P62834 BXGT011464 Ras-related protein Rap-1A 5906 reviewed Enzyme modulator
P62857 BXGT011466 40S ribosomal protein S28 6234 reviewed Nucleic acid binding
P63000 BXGT011481 Ras-related C3 botulinum toxin substrate 1 5879 reviewed Enzyme modulator
P68363 BXGT011594 Tubulin alpha-1B chain 10376 reviewed Cellular structure
P80188 BXGT011882 Neutrophil gelatinase-associated lipocalin 3934 reviewed Enzyme
P98164 BXGT012230 Low-density lipoprotein receptor-related protein 2 4036 reviewed
Q01959 BXGT012624 Sodium-dependent dopamine transporter 6531 reviewed Transporter
Q02763 BXGT012667 Angiopoietin-1 receptor 7010 reviewed Kinase
Q03164 BXGT012700 Histone-lysine N-methyltransferase 2A 4297 reviewed
Q09470 BXGT013037 Potassium voltage-gated channel subfamily A member 1 3736 reviewed Ion channel
Q13873 BXGT013398 Bone morphogenetic protein receptor type-2 659 reviewed Kinase
Q14332 BXGT013462 Frizzled-2 2535 reviewed G-protein coupled receptor
Q14683 BXGT013500 Structural maintenance of chromosomes protein 1A 8243 reviewed
Q15109 BXGT013537 Advanced glycosylation end product-specific receptor 177 reviewed Receptor
Q15389 BXGT013564 Angiopoietin-1 284 reviewed Signaling
Q15796 BXGT013599 Mothers against decapentaplegic homolog 2 4087 reviewed Transcription factor
Q2M1P5 BXGT014129 Kinesin-like protein KIF7 374654 reviewed
Q8NFD5 BXGT018560 AT-rich interactive domain-containing protein 1B 57492 reviewed
Q969G3 BXGT019607 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 6605 reviewed
Q969S2 BXGT019612 Endonuclease 8-like 2 252969 reviewed
Q99593 BXGT019939 T-box transcription factor TBX5 6910 reviewed Transcription factor
Q99814 BXGT019965 Endothelial PAS domain-containing protein 1 2034 reviewed Transcription factor
Q9BY41 BXGT020180 Histone deacetylase 8 55869 reviewed Epigenetic regulator
Q9H6Z9 BXGT020488 Egl nine homolog 3 112399 reviewed
Q9NR71 BXGT021180 Neutral ceramidase 56624 reviewed
Q9NRF2 BXGT021185 SH2B adapter protein 1 25970 reviewed
Q9NX14 BXGT021242 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial 54539 reviewed Enzyme
Q9UBM7 BXGT021657 7-dehydrocholesterol reductase 1717 reviewed Enzyme
Q9UMX1 BXGT021778 Suppressor of fused homolog 51684 reviewed
Q9Y2Q3 BXGT022242 Glutathione S-transferase kappa 1 373156 reviewed
Q92785 BXGT023424 Zinc finger protein ubi-d4 5977 reviewed Enzyme
Q99958 BXGT023732 Forkhead box protein C2 2303 reviewed Transcription factor
Q14807 BXGT024966 Kinesin-like protein KIF22 3835 reviewed Cellular structure
Q9UQE7 BXGT025899 Structural maintenance of chromosomes protein 3 9126 reviewed
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease