Showing entry for Erectile dysfunction


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD005154
Disease NameErectile dysfunction
Disease CUI IdC0242350
MeSH Codes C12   F03  
Disease Class NameMale Urogenital Diseases; Mental Disorders
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id HP:0000119  
Human Phenotype Ontology TermAbnormality of the genitourinary system
Disease Ontology Id DOID:150  
Disease Ontology Class Namedisease of mental health
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00206 BXGT003894 Toll-like receptor 4 7099 reviewed
O00255 BXGT003903 Menin 4221 reviewed
O00329 BXGT003909 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 5293 reviewed Kinase
O00748 BXGT003942 Cocaine esterase 8824 reviewed Enzyme
O14578 BXGT004072 Citron Rho-interacting kinase 11113 reviewed Kinase
O14746 BXGT004091 Telomerase reverse transcriptase 7015 reviewed Enzyme
O15123 BXGT004130 Angiopoietin-2 285 reviewed Signaling
O15379 BXGT004159 Histone deacetylase 3 8841 reviewed Epigenetic regulator
O15439 BXGT004169 Multidrug resistance-associated protein 4 10257 reviewed Transporter
O43497 BXGT004596 Voltage-dependent T-type calcium channel subunit alpha-1G 8913 reviewed Ion channel
O75116 BXGT005100 Rho-associated protein kinase 2 9475 reviewed Kinase
O76074 BXGT005174 cGMP-specific 3',5'-cyclic phosphodiesterase 8654 reviewed
O94760 BXGT005328 N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 23576 reviewed Enzyme
O95865 BXGT005404 N(G),N(G)-dimethylarginine dimethylaminohydrolase 2 23564 reviewed Enzyme
P01019 BXGT005717 Angiotensinogen 183 reviewed Enzyme modulator
P01133 BXGT005736 Pro-epidermal growth factor 1950 reviewed
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P01138 BXGT005738 Beta-nerve growth factor 4803 reviewed Signaling
P01148 BXGT005739 Progonadoliberin-1 2796 reviewed
P01189 BXGT005742 Pro-opiomelanocortin 5443 reviewed
P01236 BXGT005744 Prolactin 5617 reviewed Signaling
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P02741 BXGT005936 C-reactive protein 1401 reviewed
P02760 BXGT005948 Protein AMBP 259 reviewed
P02765 BXGT005952 Alpha-2-HS-glycoprotein 197 reviewed Enzyme modulator
P02766 BXGT005953 Transthyretin 7276 reviewed Transporter
P02768 BXGT005955 Serum albumin 213 reviewed Transporter
P02818 BXGT005969 Osteocalcin 632 reviewed
P04275 BXGT006180 von Willebrand factor 7450 reviewed Enzyme modulator
P04278 BXGT006182 Sex hormone-binding globulin 6462 reviewed
P05089 BXGT006310 Arginase-1 383 reviewed Enzyme
P05109 BXGT006318 Protein S100-A8 6279 reviewed Calcium-binding protein
P05231 BXGT006345 Interleukin-6 3569 reviewed
P06858 BXGT006515 Lipoprotein lipase 4023 reviewed Enzyme
P06870 BXGT006518 Kallikrein-1 3816 reviewed Enzyme
P07288 BXGT006591 Prostate-specific antigen 354 reviewed Enzyme
P07686 BXGT006657 Beta-hexosaminidase subunit beta 3074 reviewed Enzyme
P08922 BXGT006843 Proto-oncogene tyrosine-protein kinase ROS 6098 reviewed Kinase
P09038 BXGT006851 Fibroblast growth factor 2 2247 reviewed Signaling
P09104 BXGT006856 Gamma-enolase 2026 reviewed Enzyme
P09466 BXGT006892 Glycodelin 5047 reviewed Enzyme
P10275 BXGT007552 Androgen receptor 367 reviewed Nuclear receptor
P10415 BXGT007567 Apoptosis regulator Bcl-2 596 reviewed Signaling
P11166 BXGT007661 Solute carrier family 2, facilitated glucose transporter member 1 6513 reviewed Transporter
P11362 BXGT007693 Fibroblast growth factor receptor 1 2260 reviewed Kinase
P11511 BXGT007717 Aromatase 1588 reviewed Enzyme
P12643 BXGT007830 Bone morphogenetic protein 2 650 reviewed Signaling
P12821 BXGT007849 Angiotensin-converting enzyme 1636 reviewed Enzyme
P12931 BXGT007859 Proto-oncogene tyrosine-protein kinase Src 6714 reviewed Kinase
P13569 BXGT007923 Cystic fibrosis transmembrane conductance regulator 1080 reviewed Ion channel
P13945 BXGT007972 Beta-3 adrenergic receptor 155 reviewed G-protein coupled receptor
P14416 BXGT008011 D(2) dopamine receptor 1813 reviewed G-protein coupled receptor
P15090 BXGT008079 Fatty acid-binding protein, adipocyte 2167 reviewed
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P16066 BXGT008185 Atrial natriuretic peptide receptor 1 4881 reviewed Kinase
P16871 BXGT008269 Interleukin-7 receptor subunit alpha 3575 reviewed Receptor
P17643 BXGT008323 5,6-dihydroxyindole-2-carboxylic acid oxidase 7306 reviewed Enzyme
P17936 BXGT008357 Insulin-like growth factor-binding protein 3 3486 reviewed Enzyme modulator
P18827 BXGT008427 Syndecan-1 6382 reviewed Extracellular structure
P19429 BXGT008479 Troponin I, cardiac muscle 7137 reviewed Cellular structure
P21333 BXGT008638 Filamin-A 2316 reviewed
P21554 BXGT008662 Cannabinoid receptor 1 1268 reviewed G-protein coupled receptor
P21917 BXGT008707 D(4) dopamine receptor 1815 reviewed G-protein coupled receptor
P22303 BXGT008751 Acetylcholinesterase 43 reviewed Enzyme
P23297 BXGT008848 Protein S100-A1 6271 reviewed Calcium-binding protein
P23528 BXGT008879 Cofilin-1 1072 reviewed
P23560 BXGT008883 Brain-derived neurotrophic factor 627 reviewed Signaling
P23945 BXGT008931 Follicle-stimulating hormone receptor 2492 reviewed G-protein coupled receptor
P24298 BXGT008960 Alanine aminotransferase 1 2875 reviewed Enzyme
P24385 BXGT008965 G1/S-specific cyclin-D1 595 reviewed Enzyme modulator
P25098 BXGT009015 Beta-adrenergic receptor kinase 1 156 reviewed Kinase
P25101 BXGT009018 Endothelin-1 receptor 1909 reviewed G-protein coupled receptor
P25105 BXGT009021 Platelet-activating factor receptor 5724 reviewed G-protein coupled receptor
P25942 BXGT009079 Tumor necrosis factor receptor superfamily member 5 958 reviewed
P27169 BXGT009161 Serum paraoxonase/arylesterase 1 5444 reviewed
P28300 BXGT009243 Protein-lysine 6-oxidase 4015 reviewed
P29466 BXGT009349 Caspase-1 834 reviewed Enzyme
P29474 BXGT009352 Nitric oxide synthase, endothelial 4846 reviewed
P29475 BXGT009353 Nitric oxide synthase, brain 4842 reviewed
P30279 BXGT009415 G1/S-specific cyclin-D2 894 reviewed Enzyme modulator
P30559 BXGT009442 Oxytocin receptor 5021 reviewed G-protein coupled receptor
P31639 BXGT009556 Sodium/glucose cotransporter 2 6524 reviewed Transporter
P31749 BXGT009574 RAC-alpha serine/threonine-protein kinase 207 reviewed Kinase
P35228 BXGT009800 Nitric oxide synthase, inducible 4843 reviewed
P35348 BXGT009814 Alpha-1A adrenergic receptor 148 reviewed G-protein coupled receptor
P35610 BXGT009855 Sterol O-acyltransferase 1 6646 reviewed Enzyme
P35968 BXGT009887 Vascular endothelial growth factor receptor 2 3791 reviewed Kinase
P36955 BXGT009946 Pigment epithelium-derived factor 5176 reviewed Enzyme modulator
P40225 BXGT010168 Thrombopoietin 7066 reviewed
P40337 BXGT010174 von Hippel-Lindau disease tumor suppressor 7428 reviewed Enzyme
P41231 BXGT010240 P2Y purinoceptor 2 5029 reviewed G-protein coupled receptor
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 5290 reviewed Kinase
P42338 BXGT010303 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 5291 reviewed Kinase
P42574 BXGT010317 Caspase-3 836 reviewed Enzyme
P42898 BXGT010344 Methylenetetrahydrofolate reductase 4524 reviewed
P45983 BXGT010494 Mitogen-activated protein kinase 8 5599 reviewed Kinase
P47900 BXGT010595 P2Y purinoceptor 1 5028 reviewed G-protein coupled receptor
P48061 BXGT010616 Stromal cell-derived factor 1 6387 reviewed
P48736 BXGT010658 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 5294 reviewed Kinase
P49419 BXGT010705 Alpha-aminoadipic semialdehyde dehydrogenase 501 reviewed Enzyme
P49585 BXGT010712 Choline-phosphate cytidylyltransferase A 5130 reviewed
P49747 BXGT010732 Cartilage oligomeric matrix protein 1311 reviewed
P49902 BXGT010758 Cytosolic purine 5'-nucleotidase 22978 reviewed Enzyme
P49913 BXGT010761 Cathelicidin antimicrobial peptide 820 reviewed
P53667 BXGT011008 LIM domain kinase 1 3984 reviewed Kinase
P53671 BXGT011009 LIM domain kinase 2 3985 reviewed Kinase
P54868 BXGT011090 Hydroxymethylglutaryl-CoA synthase, mitochondrial 3158 reviewed
P60709 BXGT011322 Actin, cytoplasmic 1 60 reviewed Cellular structure
P63000 BXGT011481 Ras-related C3 botulinum toxin substrate 1 5879 reviewed Enzyme modulator
P78540 BXGT011848 Arginase-2, mitochondrial 384 reviewed Enzyme
P81172 BXGT011935 Hepcidin 57817 reviewed
Q02108 BXGT012634 Guanylate cyclase soluble subunit alpha-1 2982 reviewed
Q06787 BXGT012890 Synaptic functional regulator FMR1 2332 reviewed Nucleic acid binding
Q07812 BXGT012940 Apoptosis regulator BAX 581 reviewed Signaling
Q07817 BXGT012941 Bcl-2-like protein 1 598 reviewed Signaling
Q12791 BXGT013264 Calcium-activated potassium channel subunit alpha-1 3778 reviewed Ion channel
Q13315 BXGT013339 Serine-protein kinase ATM 472 reviewed Kinase
Q13418 BXGT013351 Integrin-linked protein kinase 3611 reviewed Kinase
Q13464 BXGT013357 Rho-associated protein kinase 1 6093 reviewed Kinase
Q13976 BXGT013409 cGMP-dependent protein kinase 1 5592 reviewed Kinase
Q14289 BXGT013459 Protein-tyrosine kinase 2-beta 2185 reviewed Kinase
Q14432 BXGT013469 cGMP-inhibited 3',5'-cyclic phosphodiesterase A 5139 reviewed
Q15109 BXGT013537 Advanced glycosylation end product-specific receptor 177 reviewed Receptor
Q15223 BXGT013551 Nectin-1 5818 reviewed
Q15389 BXGT013564 Angiopoietin-1 284 reviewed Signaling
Q15465 BXGT013573 Sonic hedgehog protein 6469 reviewed
Q15848 BXGT013609 Adiponectin 9370 reviewed
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 4780 reviewed Enzyme
Q16698 BXGT013659 2,4-dienoyl-CoA reductase, mitochondrial 1666 reviewed Enzyme
Q16828 BXGT013676 Dual specificity protein phosphatase 6 1848 reviewed
Q30201 BXGT014297 Hereditary hemochromatosis protein 3077 reviewed
Q59FK2 BXGT015276 Selenocysteine lyase variant 51540 unreviewed
Q6ZVN8 BXGT016641 Hemojuvelin 148738 reviewed
Q7Z2W7 BXGT017248 Transient receptor potential cation channel subfamily M member 8 79054 reviewed Ion channel
Q8NBP7 BXGT018541 Proprotein convertase subtilisin/kexin type 9 255738 reviewed Enzyme
Q8NCC3 BXGT018546 Group XV phospholipase A2 23659 reviewed Enzyme
Q8TCU5 BXGT018802 Glutamate receptor ionotropic, NMDA 3A 116443 reviewed Ion channel
Q8WY64 BXGT019017 E3 ubiquitin-protein ligase MYLIP 29116 reviewed
Q92934 BXGT019396 Bcl2-associated agonist of cell death 572 reviewed
Q96EB6 BXGT019646 NAD-dependent protein deacetylase sirtuin-1 23411 reviewed Epigenetic regulator
Q96I15 BXGT019674 Selenocysteine lyase 51540 reviewed Enzyme
Q99836 BXGT019970 Myeloid differentiation primary response protein MyD88 4615 reviewed Enzyme modulator
Q9BY08 BXGT020177 Emopamil-binding protein-like 84650 reviewed Enzyme
Q9H251 BXGT020449 Cadherin-23 64072 reviewed
Q9NR19 BXGT021175 Acetyl-coenzyme A synthetase, cytoplasmic 55902 reviewed Enzyme
Q9NZJ4 BXGT021274 Sacsin 26278 reviewed
Q9UHF0 BXGT021699 Tachykinin-3 6866 reviewed
Q9UMX1 BXGT021778 Suppressor of fused homolog 51684 reviewed
P35240 BXGT022927 Merlin 4771 reviewed
O14793 BXGT023280 Growth/differentiation factor 8 2660 reviewed Signaling
P63167 BXGT024120 Dynein light chain 1, cytoplasmic 8655 reviewed Cellular structure
Q02153 BXGT024538 Guanylate cyclase soluble subunit beta-1 2983 reviewed
P00403 BXGT026137 Cytochrome c oxidase subunit 2 4513 reviewed Enzyme
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease