adisease

Showing entry for Acute Lung Injury

General Disease Information
BXGD Id	BXGD005170
Disease Name	Acute Lung Injury
Disease CUI Id	C0242488
MeSH Codes	C08
Disease Class Name	Respiratory Tract Diseases
Semantic Type	Injury or Poisoning
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O00206	BXGT003894	Toll-like receptor 4	7099	reviewed
O60313	BXGT004871	Dynamin-like 120 kDa protein, mitochondrial	4976	reviewed	Enzyme modulator
P00390	BXGT005526	Glutathione reductase, mitochondrial	2936	reviewed	Enzyme
P00734	BXGT005630	Prothrombin	2147	reviewed	Enzyme
P00749	BXGT005641	Urokinase-type plasminogen activator	5328	reviewed	Enzyme
P01024	BXGT005719	Complement C3	718	reviewed	Enzyme modulator
P01137	BXGT005737	Transforming growth factor beta-1 proprotein	7040	reviewed	Signaling
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01579	BXGT005770	Interferon gamma	3458	reviewed
P01584	BXGT005772	Interleukin-1 beta	3553	reviewed
P02647	BXGT005908	Apolipoprotein A-I	335	reviewed
P02671	BXGT005914	Fibrinogen alpha chain	2243	reviewed
P02768	BXGT005955	Serum albumin	213	reviewed	Transporter
P04040	BXGT006132	Catalase	847	reviewed	Enzyme
P04155	BXGT006155	Trefoil factor 1	7031	reviewed	Signaling
P04798	BXGT006265	Cytochrome P450 1A1	1543	reviewed	Enzyme
P05107	BXGT006316	Integrin beta-2	3689	reviewed	Receptor
P05121	BXGT006320	Plasminogen activator inhibitor 1	5054	reviewed	Enzyme modulator
P05231	BXGT006345	Interleukin-6	3569	reviewed
P05362	BXGT006350	Intercellular adhesion molecule 1	3383	reviewed
P07099	BXGT006546	Epoxide hydrolase 1	2052	reviewed
P07204	BXGT006567	Thrombomodulin	7056	reviewed
P08246	BXGT006756	Neutrophil elastase	1991	reviewed	Enzyme
P08253	BXGT006757	72 kDa type IV collagenase	4313	reviewed	Enzyme
P08913	BXGT006841	Alpha-2A adrenergic receptor	150	reviewed	G-protein coupled receptor
P09237	BXGT006874	Matrilysin	4316	reviewed	Enzyme
P09429	BXGT006889	High mobility group protein B1	3146	reviewed	Nucleic acid binding
P09601	BXGT006909	Heme oxygenase 1	3162	reviewed
P10415	BXGT007567	Apoptosis regulator Bcl-2	596	reviewed	Signaling
P10599	BXGT007583	Thioredoxin	7295	reviewed
P12314	BXGT007798	High affinity immunoglobulin gamma Fc receptor I	2209	reviewed	Cell adhesion
P12318	BXGT007799	Low affinity immunoglobulin gamma Fc region receptor II-a	2212	reviewed	Cell adhesion
P13236	BXGT007891	C-C motif chemokine 4	6351	reviewed
P13500	BXGT007916	C-C motif chemokine 2	6347	reviewed	Signaling
P13726	BXGT007950	Tissue factor	2152	reviewed	Receptor
P14555	BXGT008020	Phospholipase A2, membrane associated	5320	reviewed	Enzyme
P14780	BXGT008053	Matrix metalloproteinase-9	4318	reviewed	Enzyme
P15559	BXGT008139	NAD(P)H dehydrogenase [quinone] 1	1728	reviewed
P15692	BXGT008147	Vascular endothelial growth factor A	7422	reviewed	Signaling
P17174	BXGT008289	Aspartate aminotransferase, cytoplasmic	2805	reviewed
P17948	BXGT008358	Vascular endothelial growth factor receptor 1	2321	reviewed	Kinase
P34913	BXGT009770	Bifunctional epoxide hydrolase 2	2053	reviewed	Enzyme
P35228	BXGT009800	Nitric oxide synthase, inducible	4843	reviewed
P35247	BXGT009804	Pulmonary surfactant-associated protein D	6441	reviewed	Surfactant
P35354	BXGT009816	Prostaglandin G/H synthase 2	5743	reviewed	Enzyme
P35968	BXGT009887	Vascular endothelial growth factor receptor 2	3791	reviewed	Kinase
P37231	BXGT009972	Peroxisome proliferator-activated receptor gamma	5468	reviewed	Nuclear receptor
P42574	BXGT010317	Caspase-3	836	reviewed	Enzyme
P47989	BXGT010602	Xanthine dehydrogenase/oxidase	7498	reviewed	Enzyme
P48023	BXGT010604	Tumor necrosis factor ligand superfamily member 6	356	reviewed	Signaling
P55265	BXGT011117	Double-stranded RNA-specific adenosine deaminase	103	reviewed	Enzyme
P60568	BXGT011315	Interleukin-2	3558	reviewed
P98066	BXGT012225	Tumor necrosis factor-inducible gene 6 protein	7130	reviewed
Q03403	BXGT012712	Trefoil factor 2	7032	reviewed	Signaling
Q04771	BXGT012783	Activin receptor type-1	90	reviewed	Kinase
Q04912	BXGT012790	Macrophage-stimulating protein receptor	4486	reviewed	Kinase
Q07812	BXGT012940	Apoptosis regulator BAX	581	reviewed	Signaling
Q13153	BXGT013319	Serine/threonine-protein kinase PAK 1	5058	reviewed	Kinase
Q14116	BXGT013442	Interleukin-18	3606	reviewed
Q14790	BXGT013505	Caspase-8	841	reviewed	Enzyme
Q15109	BXGT013537	Advanced glycosylation end product-specific receptor	177	reviewed	Receptor
Q15746	BXGT013591	Myosin light chain kinase, smooth muscle	4638	reviewed	Kinase
Q16236	BXGT013624	Nuclear factor erythroid 2-related factor 2	4780	reviewed	Enzyme
Q8IWA4	BXGT018353	Mitofusin-1	55669	reviewed	Enzyme
Q9H244	BXGT020448	P2Y purinoceptor 12	64805	reviewed	G-protein coupled receptor
Q9HC29	BXGT020526	Nucleotide-binding oligomerization domain-containing protein 2	64127	reviewed	Enzyme
Q9UNN8	BXGT021791	Endothelial protein C receptor	10544	reviewed	Enzyme modulator
P16284	BXGT022972	Platelet endothelial cell adhesion molecule	5175	reviewed	Cell adhesion
P19875	BXGT023294	C-X-C motif chemokine 2	2920	reviewed	Signaling
P31994	BXGT023298	Low affinity immunoglobulin gamma Fc region receptor II-b	2213	reviewed	Cell adhesion
Q16552	BXGT023419	Interleukin-17A	3605	reviewed
O95140	BXGT024482	Mitofusin-2	9927	reviewed	Enzyme

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}