Showing entry for Systemic Inflammatory Response Syndrome


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD005201
Disease NameSystemic Inflammatory Response Syndrome
Disease CUI IdC0242966
MeSH Codes C23  
Disease Class NamePathological Conditions, Signs and Symptoms
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00187 BXGT003890 Mannan-binding lectin serine protease 2 10747 reviewed Enzyme
O00206 BXGT003894 Toll-like receptor 4 7099 reviewed
O00329 BXGT003909 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 5293 reviewed Kinase
O14786 BXGT004099 Neuropilin-1 8829 reviewed
O14964 BXGT004116 Hepatocyte growth factor-regulated tyrosine kinase substrate 9146 reviewed
O15553 BXGT004181 Pyrin 4210 reviewed
O43854 BXGT004630 EGF-like repeat and discoidin I-like domain-containing protein 3 10085 reviewed Enzyme
O60603 BXGT004887 Toll-like receptor 2 7097 reviewed
O60858 BXGT004903 E3 ubiquitin-protein ligase TRIM13 10206 reviewed
O75636 BXGT005141 Ficolin-3 8547 reviewed Signaling
O95405 BXGT005379 Zinc finger FYVE domain-containing protein 9 9372 reviewed
P00480 BXGT005551 Ornithine carbamoyltransferase, mitochondrial 5009 reviewed
P00734 BXGT005630 Prothrombin 2147 reviewed Enzyme
P00747 BXGT005639 Plasminogen 5340 reviewed Enzyme
P01009 BXGT005714 Alpha-1-antitrypsin 5265 reviewed Enzyme modulator
P01270 BXGT005746 Parathyroid hormone 5741 reviewed
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01579 BXGT005770 Interferon gamma 3458 reviewed
P01583 BXGT005771 Interleukin-1 alpha 3552 reviewed
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P02741 BXGT005936 C-reactive protein 1401 reviewed
P02768 BXGT005955 Serum albumin 213 reviewed Transporter
P02775 BXGT005960 Platelet basic protein 5473 reviewed Signaling
P03372 BXGT006059 Estrogen receptor 2099 reviewed Nuclear receptor
P04150 BXGT006154 Glucocorticoid receptor 2908 reviewed Nuclear receptor
P04839 BXGT006273 Cytochrome b-245 heavy chain 1536 reviewed Ion channel
P05091 BXGT006312 Aldehyde dehydrogenase, mitochondrial 217 reviewed Enzyme
P05107 BXGT006316 Integrin beta-2 3689 reviewed Receptor
P05121 BXGT006320 Plasminogen activator inhibitor 1 5054 reviewed Enzyme modulator
P05187 BXGT006339 Alkaline phosphatase, placental type 250 reviewed Enzyme
P05231 BXGT006345 Interleukin-6 3569 reviewed
P05362 BXGT006350 Intercellular adhesion molecule 1 3383 reviewed
P05556 BXGT006368 Integrin beta-1 3688 reviewed Receptor
P06396 BXGT006435 Gelsolin 2934 reviewed Cellular structure
P07204 BXGT006567 Thrombomodulin 7056 reviewed
P07288 BXGT006591 Prostate-specific antigen 354 reviewed Enzyme
P07384 BXGT006619 Calpain-1 catalytic subunit 823 reviewed Enzyme
P07550 BXGT006636 Beta-2 adrenergic receptor 154 reviewed G-protein coupled receptor
P07900 BXGT006696 Heat shock protein HSP 90-alpha 3320 reviewed Chaperone
P08603 BXGT006798 Complement factor H 3075 reviewed
P09429 BXGT006889 High mobility group protein B1 3146 reviewed Nucleic acid binding
P09601 BXGT006909 Heme oxygenase 1 3162 reviewed
P0DMV8 BXGT007509 Heat shock 70 kDa protein 1A 3304 reviewed
P0DMV9 BXGT007510 Heat shock 70 kDa protein 1B 3304 reviewed
P10145 BXGT007542 Interleukin-8 3576 reviewed Signaling
P10644 BXGT007597 cAMP-dependent protein kinase type I-alpha regulatory subunit 5573 reviewed
P10747 BXGT007609 T-cell-specific surface glycoprotein CD28 940 reviewed
P11226 BXGT007675 Mannose-binding protein C 4153 reviewed Receptor
P12081 BXGT007772 Histidine--tRNA ligase, cytoplasmic 3035 reviewed Enzyme
P12273 BXGT007787 Prolactin-inducible protein 5304 reviewed
P12314 BXGT007798 High affinity immunoglobulin gamma Fc receptor I 2209 reviewed Cell adhesion
P13500 BXGT007916 C-C motif chemokine 2 6347 reviewed Signaling
P13726 BXGT007950 Tissue factor 2152 reviewed Receptor
P14151 BXGT007990 L-selectin 6402 reviewed
P14174 BXGT007991 Macrophage migration inhibitory factor 4282 reviewed
P14210 BXGT007994 Hepatocyte growth factor 3082 reviewed Enzyme
P15169 BXGT008093 Carboxypeptidase N catalytic chain 1369 reviewed
P16581 BXGT008245 E-selectin 6401 reviewed
P19429 BXGT008479 Troponin I, cardiac muscle 7137 reviewed Cellular structure
P19838 BXGT008526 Nuclear factor NF-kappa-B p105 subunit 4790 reviewed Transcription factor
P21580 BXGT008666 Tumor necrosis factor alpha-induced protein 3 7128 reviewed Enzyme
P21730 BXGT008687 C5a anaphylatoxin chemotactic receptor 1 728 reviewed G-protein coupled receptor
P25024 BXGT009005 C-X-C chemokine receptor type 1 3577 reviewed G-protein coupled receptor
P29466 BXGT009349 Caspase-1 834 reviewed Enzyme
P34932 BXGT009772 Heat shock 70 kDa protein 4 3308 reviewed
P35228 BXGT009800 Nitric oxide synthase, inducible 4843 reviewed
P36222 BXGT009914 Chitinase-3-like protein 1 1116 reviewed
P36544 BXGT009926 Neuronal acetylcholine receptor subunit alpha-7 89832 reviewed
P41180 BXGT010230 Extracellular calcium-sensing receptor 846 reviewed G-protein coupled receptor
P42336 BXGT010302 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 5290 reviewed Kinase
P42338 BXGT010303 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 5291 reviewed Kinase
P43652 BXGT010405 Afamin 173 reviewed Transporter
P48544 BXGT010641 G protein-activated inward rectifier potassium channel 4 3762 reviewed Ion channel
P48736 BXGT010658 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 5294 reviewed Kinase
P49589 BXGT010714 Cysteine--tRNA ligase, cytoplasmic 833 reviewed Enzyme
P50750 BXGT010818 Cyclin-dependent kinase 9 1025 reviewed Kinase
P52594 BXGT010936 Arf-GAP domain and FG repeat-containing protein 1 3267 reviewed
P60484 BXGT011307 Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN 5728 reviewed Enzyme
P62937 BXGT011471 Peptidyl-prolyl cis-trans isomerase A 5478 reviewed
P62942 BXGT011474 Peptidyl-prolyl cis-trans isomerase FKBP1A 2280 reviewed Enzyme
P78310 BXGT011830 Coxsackievirus and adenovirus receptor 1525 reviewed
P80188 BXGT011882 Neutrophil gelatinase-associated lipocalin 3934 reviewed Enzyme
Q01726 BXGT012610 Melanocyte-stimulating hormone receptor 4157 reviewed G-protein coupled receptor
Q13546 BXGT013372 Receptor-interacting serine/threonine-protein kinase 1 8737 reviewed Kinase
Q14994 BXGT013519 Nuclear receptor subfamily 1 group I member 3 9970 reviewed Nuclear receptor
Q16236 BXGT013624 Nuclear factor erythroid 2-related factor 2 4780 reviewed Enzyme
Q7L266 BXGT016993 Isoaspartyl peptidase/L-asparaginase 80150 reviewed Enzyme
Q8IXJ6 BXGT018362 NAD-dependent protein deacetylase sirtuin-2 22933 reviewed Epigenetic regulator
Q96P20 BXGT019704 NACHT, LRR and PYD domains-containing protein 3 114548 reviewed
Q9BWP8 BXGT020153 Collectin-11 78989 reviewed Surfactant
Q9H0A0 BXGT020434 RNA cytidine acetyltransferase 55226 reviewed
Q9HC29 BXGT020526 Nucleotide-binding oligomerization domain-containing protein 2 64127 reviewed Enzyme
Q9NR96 BXGT021181 Toll-like receptor 9 54106 reviewed
Q9NWZ3 BXGT021239 Interleukin-1 receptor-associated kinase 4 51135 reviewed Kinase
Q9NZQ7 BXGT021281 Programmed cell death 1 ligand 1 29126 reviewed Receptor
Q9P246 BXGT021298 Stromal interaction molecule 2 57620 reviewed
Q9UM07 BXGT021771 Protein-arginine deiminase type-4 23569 reviewed
Q9Y4B6 BXGT022272 DDB1- and CUL4-associated factor 1 9730 reviewed
Q9Y572 BXGT022289 Receptor-interacting serine/threonine-protein kinase 3 11035 reviewed Kinase
Q9Y5Y9 BXGT022309 Sodium channel protein type 10 subunit alpha 6336 reviewed Ion channel
Q9Y6Y9 BXGT022346 Lymphocyte antigen 96 23643 reviewed Receptor
P00738 BXGT022874 Haptoglobin 3240 reviewed Enzyme
Q9UM82 BXGT023181 Spermatogenesis-associated protein 2 9825 reviewed
P00395 BXGT023596 Cytochrome c oxidase subunit 1 4512 reviewed Enzyme
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease