adisease

Showing entry for Seckel syndrome

General Disease Information
BXGD Id	BXGD005461
Disease Name	Seckel syndrome
Disease CUI Id	C0265202
MeSH Codes	C23 C16 C05 C10 C19
Disease Class Name	Pathological Conditions, Signs and Symptoms; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Musculoskeletal Diseases; Nervous System Diseases; Endocrine System Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id	DOID:630 DOID:7 DOID:225 DOID:150
Disease Ontology Class Name	genetic disease; disease of anatomical entity; syndrome; disease of mental health
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
A0A024RAV5	BXGT000013	V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b	3845	unreviewed
O00444	BXGT003921	Serine/threonine-protein kinase PLK4	10733	reviewed	Kinase
O14757	BXGT004092	Serine/threonine-protein kinase Chk1	1111	reviewed	Kinase
O43929	BXGT004638	Origin recognition complex subunit 4	5000	reviewed	Nucleic acid binding
O75496	BXGT005132	Geminin	51053	reviewed
P01116	BXGT005733	GTPase KRas	3845	reviewed	Enzyme modulator
P04049	BXGT006133	RAF proto-oncogene serine/threonine-protein kinase	5894	reviewed	Kinase
P16930	BXGT008272	Fumarylacetoacetase	2184	reviewed
P26358	BXGT009104	DNA (cytosine-5)-methyltransferase 1	1786	reviewed	Epigenetic regulator
P28482	BXGT009263	Mitogen-activated protein kinase 1	5594	reviewed	Kinase
P38398	BXGT010037	Breast cancer type 1 susceptibility protein	672	reviewed	Enzyme
P46108	BXGT010509	Adapter molecule crk	1398	reviewed
P49917	BXGT010765	DNA ligase 4	3981	reviewed
Q02224	BXGT012643	Centromere-associated protein E	1062	reviewed	Cellular structure
Q06124	BXGT012856	Tyrosine-protein phosphatase non-receptor type 11	5781	reviewed
Q07108	BXGT012919	Early activation antigen CD69	969	reviewed
Q07889	BXGT012946	Son of sevenless homolog 1	6654	reviewed	Enzyme modulator
Q13155	BXGT013320	Aminoacyl tRNA synthase complex-interacting multifunctional protein 2	7965	reviewed
Q13315	BXGT013339	Serine-protein kinase ATM	472	reviewed	Kinase
Q13415	BXGT013350	Origin recognition complex subunit 1	4998	reviewed	Nucleic acid binding
Q13426	BXGT013353	DNA repair protein XRCC4	7518	reviewed
Q13535	BXGT013370	Serine/threonine-protein kinase ATR	545	reviewed	Kinase
Q16539	BXGT013634	Mitogen-activated protein kinase 14	1432	reviewed	Kinase
Q4G0J3	BXGT014809	La-related protein 7	51574	reviewed	Nucleic acid binding
Q8NEM0	BXGT018555	Microcephalin	79648	reviewed	Nucleic acid binding
Q92963	BXGT019401	GTP-binding protein Rit1	6016	reviewed	Enzyme modulator
Q96T60	BXGT019745	Bifunctional polynucleotide phosphatase/kinase	11284	reviewed
Q9Y6K1	BXGT022331	DNA (cytosine-5)-methyltransferase 3A	1788	reviewed
P16104	BXGT024571	Histone H2AX	3014	reviewed	Nucleic acid binding

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}