Showing entry for Idiopathic generalized epilepsy


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD006117
Disease NameIdiopathic generalized epilepsy
Disease CUI IdC0270850
MeSH Codes C10  
Disease Class NameNervous System Diseases
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id DOID:7  
Disease Ontology Class Namedisease of anatomical entity
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00222 BXGT003899 Metabotropic glutamate receptor 8 2918 reviewed G-protein coupled receptor
O00305 BXGT003907 Voltage-dependent L-type calcium channel subunit beta-4 785 reviewed Ion channel
O00555 BXGT003936 Voltage-dependent P/Q-type calcium channel subunit alpha-1A 773 reviewed Ion channel
O14764 BXGT004094 Gamma-aminobutyric acid receptor subunit delta 2563 reviewed Ion channel
O43497 BXGT004596 Voltage-dependent T-type calcium channel subunit alpha-1G 8913 reviewed Ion channel
O60741 BXGT004897 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 348980 reviewed
O75311 BXGT005109 Glycine receptor subunit alpha-3 8001 reviewed Ion channel
O95180 BXGT005358 Voltage-dependent T-type calcium channel subunit alpha-1H 8912 reviewed Ion channel
O95970 BXGT005409 Leucine-rich glioma-inactivated protein 1 9211 reviewed
P00488 BXGT005552 Coagulation factor XIII A chain 2162 reviewed Enzyme
P01583 BXGT005771 Interleukin-1 alpha 3552 reviewed
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P02741 BXGT005936 C-reactive protein 1401 reviewed
P05231 BXGT006345 Interleukin-6 3569 reviewed
P07225 BXGT006572 Vitamin K-dependent protein S 5627 reviewed
P11166 BXGT007661 Solute carrier family 2, facilitated glucose transporter member 1 6513 reviewed Transporter
P14867 BXGT008061 Gamma-aminobutyric acid receptor subunit alpha-1 2554 reviewed Ion channel
P17787 BXGT008341 Neuronal acetylcholine receptor subunit beta-2 1141 reviewed Ion channel
P18507 BXGT008411 Gamma-aminobutyric acid receptor subunit gamma-2 2566 reviewed Ion channel
P20807 BXGT008601 Calpain-3 825 reviewed Enzyme
P21397 BXGT008644 Amine oxidase [flavin-containing] A 4128 reviewed
P23368 BXGT008856 NAD-dependent malic enzyme, mitochondrial 4200 reviewed Enzyme
P24666 BXGT008986 Low molecular weight phosphotyrosine protein phosphatase 52 reviewed
P25440 BXGT009044 Bromodomain-containing protein 2 6046 reviewed Epigenetic regulator
P28335 BXGT009255 5-hydroxytryptamine receptor 2C 3358 reviewed G-protein coupled receptor
P28472 BXGT009260 Gamma-aminobutyric acid receptor subunit beta-3 2562 reviewed Ion channel
P30711 BXGT009460 Glutathione S-transferase theta-1 2952 reviewed
P35372 BXGT009823 Mu-type opioid receptor 4988 reviewed G-protein coupled receptor
P35498 BXGT009838 Sodium channel protein type 1 subunit alpha 6323 reviewed Ion channel
P36544 BXGT009926 Neuronal acetylcholine receptor subunit alpha-7 89832 reviewed
P39086 BXGT010093 Glutamate receptor ionotropic, kainate 1 2897 reviewed Ion channel
P40763 BXGT010202 Signal transducer and activator of transcription 3 6774 reviewed Nucleic acid binding
P41180 BXGT010230 Extracellular calcium-sensing receptor 846 reviewed G-protein coupled receptor
P43004 BXGT010348 Excitatory amino acid transporter 2 6506 reviewed Transporter
P43405 BXGT010386 Tyrosine-protein kinase SYK 6850 reviewed Kinase
P43681 BXGT010407 Neuronal acetylcholine receptor subunit alpha-4 1137 reviewed Ion channel
P48051 BXGT010611 G protein-activated inward rectifier potassium channel 2 3763 reviewed Ion channel
P48549 BXGT010644 G protein-activated inward rectifier potassium channel 1 3760 reviewed Ion channel
P50993 BXGT010826 Sodium/potassium-transporting ATPase subunit alpha-2 477 reviewed Transporter
P51649 BXGT010872 Succinate-semialdehyde dehydrogenase, mitochondrial 7915 reviewed Enzyme
P58400 BXGT011235 Neurexin-1-beta 9378 reviewed
P78508 BXGT011845 ATP-sensitive inward rectifier potassium channel 10 3766 reviewed Ion channel
Q01959 BXGT012624 Sodium-dependent dopamine transporter 6531 reviewed Transporter
Q05901 BXGT012842 Neuronal acetylcholine receptor subunit beta-3 1142 reviewed Ion channel
Q12879 BXGT013275 Glutamate receptor ionotropic, NMDA 2A 2903 reviewed Ion channel
Q14116 BXGT013442 Interleukin-18 3606 reviewed
Q14831 BXGT013506 Metabotropic glutamate receptor 7 2917 reviewed G-protein coupled receptor
Q14833 BXGT013508 Metabotropic glutamate receptor 4 2914 reviewed G-protein coupled receptor
Q16445 BXGT013629 Gamma-aminobutyric acid receptor subunit alpha-6 2559 reviewed Ion channel
Q86Y07 BXGT017631 Serine/threonine-protein kinase VRK2 7444 reviewed Kinase
Q92736 BXGT019367 Ryanodine receptor 2 6262 reviewed Ion channel
Q99250 BXGT019913 Sodium channel protein type 2 subunit alpha 6326 reviewed Ion channel
Q9BXD5 BXGT020166 N-acetylneuraminate lyase 80896 reviewed Enzyme
Q9H2X9 BXGT020459 Solute carrier family 12 member 5 57468 reviewed Transporter
Q9NQX3 BXGT021172 Gephyrin 10243 reviewed
Q9NVS9 BXGT021228 Pyridoxine-5'-phosphate oxidase 55163 reviewed Enzyme
Q9NWB1 BXGT021231 RNA binding protein fox-1 homolog 1 54715 reviewed Nucleic acid binding
Q9UBS5 BXGT021662 Gamma-aminobutyric acid type B receptor subunit 1 2550 reviewed G-protein coupled receptor
Q9UK17 BXGT021735 Potassium voltage-gated channel subfamily D member 3 3752 reviewed Ion channel
Q9UL51 BXGT021754 Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 610 reviewed Ion channel
P00738 BXGT022874 Haptoglobin 3240 reviewed Enzyme
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease