Showing entry for Hypogonadotropic hypogonadism


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD006222
Disease NameHypogonadotropic hypogonadism
Disease CUI IdC0271623
MeSH Codes C19  
Disease Class NameEndocrine System Diseases
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id HP:0000119   HP:0000818  
Human Phenotype Ontology TermAbnormality of the genitourinary system; Abnormality of the endocrine system
Disease Ontology Id DOID:630   DOID:7  
Disease Ontology Class Namegenetic disease; disease of anatomical entity
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
A0A024RAV5 BXGT000013 V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog, isoform CRA_b 3845 unreviewed
O00255 BXGT003903 Menin 4221 reviewed
O14786 BXGT004099 Neuropilin-1 8829 reviewed
O15305 BXGT004152 Phosphomannomutase 2 5373 reviewed Enzyme
O43323 BXGT004587 Desert hedgehog protein 50846 reviewed
O60260 BXGT004864 E3 ubiquitin-protein ligase parkin 5071 reviewed Enzyme
O60462 BXGT004876 Neuropilin-2 8828 reviewed
O75844 BXGT005156 CAAX prenyl protease 1 homolog 10269 reviewed Enzyme
O76074 BXGT005174 cGMP-specific 3',5'-cyclic phosphodiesterase 8654 reviewed
O95631 BXGT005387 Netrin-1 9423 reviewed Enzyme modulator
O95718 BXGT005392 Steroid hormone receptor ERR2 2103 reviewed Nuclear receptor
P01111 BXGT005731 GTPase NRas 4893 reviewed Enzyme modulator
P01116 BXGT005733 GTPase KRas 3845 reviewed Enzyme modulator
P01138 BXGT005738 Beta-nerve growth factor 4803 reviewed Signaling
P01148 BXGT005739 Progonadoliberin-1 2796 reviewed
P01189 BXGT005742 Pro-opiomelanocortin 5443 reviewed
P01236 BXGT005744 Prolactin 5617 reviewed Signaling
P02545 BXGT005889 Prelamin-A/C 4000 reviewed
P04049 BXGT006133 RAF proto-oncogene serine/threonine-protein kinase 5894 reviewed Kinase
P04278 BXGT006182 Sex hormone-binding globulin 6462 reviewed
P05093 BXGT006313 Steroid 17-alpha-hydroxylase/17,20 lyase 1586 reviewed
P09038 BXGT006851 Fibroblast growth factor 2 2247 reviewed Signaling
P10070 BXGT007534 Zinc finger protein GLI2 2736 reviewed
P10275 BXGT007552 Androgen receptor 367 reviewed Nuclear receptor
P10301 BXGT007556 Ras-related protein R-Ras 6237 reviewed Enzyme modulator
P11362 BXGT007693 Fibroblast growth factor receptor 1 2260 reviewed Kinase
P11473 BXGT007709 Vitamin D3 receptor 7421 reviewed Nuclear receptor
P11511 BXGT007717 Aromatase 1588 reviewed Enzyme
P11766 BXGT007745 Alcohol dehydrogenase class-3 128 reviewed Enzyme
P12643 BXGT007830 Bone morphogenetic protein 2 650 reviewed Signaling
P15056 BXGT008075 Serine/threonine-protein kinase B-raf 673 reviewed Kinase
P16157 BXGT008203 Ankyrin-1 286 reviewed
P16410 BXGT008224 Cytotoxic T-lymphocyte protein 4 1493 reviewed
P19544 BXGT008494 Wilms tumor protein 7490 reviewed Nucleic acid binding
P19971 BXGT008537 Thymidine phosphorylase 1890 reviewed Enzyme
P21453 BXGT008654 Sphingosine 1-phosphate receptor 1 1901 reviewed G-protein coupled receptor
P21589 BXGT008669 5'-nucleotidase 4907 reviewed Enzyme
P25440 BXGT009044 Bromodomain-containing protein 2 6046 reviewed Epigenetic regulator
P26447 BXGT009114 Protein S100-A4 6275 reviewed Calcium-binding protein
P29033 BXGT009308 Gap junction beta-2 protein 2706 reviewed Cell-cell junction
P29622 BXGT009370 Kallistatin 5267 reviewed Enzyme modulator
P30530 BXGT009431 Tyrosine-protein kinase receptor UFO 558 reviewed Kinase
P32245 BXGT009614 Melanocortin receptor 4 4160 reviewed G-protein coupled receptor
P35222 BXGT009799 Catenin beta-1 1499 reviewed
P37058 BXGT009956 Testosterone 17-beta-dehydrogenase 3 3293 reviewed
P48357 BXGT010627 Leptin receptor 3953 reviewed Signaling
P51843 BXGT010897 Nuclear receptor subfamily 0 group B member 1 190 reviewed Nuclear receptor
P53667 BXGT011008 LIM domain kinase 1 3984 reviewed Kinase
P54098 BXGT011030 DNA polymerase subunit gamma-1 5428 reviewed Enzyme
Q01453 BXGT012588 Peripheral myelin protein 22 5376 reviewed Cellular structure
Q06124 BXGT012856 Tyrosine-protein phosphatase non-receptor type 11 5781 reviewed
Q06418 BXGT012875 Tyrosine-protein kinase receptor TYRO3 7301 reviewed Kinase
Q06609 BXGT012884 DNA repair protein RAD51 homolog 1 5888 reviewed
Q07889 BXGT012946 Son of sevenless homolog 1 6654 reviewed Enzyme modulator
Q13233 BXGT013330 Mitogen-activated protein kinase kinase kinase 1 4214 reviewed Kinase
Q13285 BXGT013335 Steroidogenic factor 1 2516 reviewed Nuclear receptor
Q13509 BXGT013366 Tubulin beta-3 chain 10381 reviewed Cellular structure
Q14457 BXGT013472 Beclin-1 8678 reviewed Enzyme modulator
Q16828 BXGT013676 Dual specificity protein phosphatase 6 1848 reviewed
Q30201 BXGT014297 Hereditary hemochromatosis protein 3077 reviewed
Q6WRI0 BXGT016596 Immunoglobulin superfamily member 10 285313 reviewed
Q6ZVN8 BXGT016641 Hemojuvelin 148738 reviewed
Q7LG56 BXGT016999 Ribonucleoside-diphosphate reductase subunit M2 B 50484 reviewed Enzyme
Q92963 BXGT019401 GTP-binding protein Rit1 6016 reviewed Enzyme modulator
Q9BY41 BXGT020180 Histone deacetylase 8 55869 reviewed Epigenetic regulator
Q9H251 BXGT020449 Cadherin-23 64072 reviewed
Q9NZQ7 BXGT021281 Programmed cell death 1 ligand 1 29126 reviewed Receptor
Q9UHF0 BXGT021699 Tachykinin-3 6866 reviewed
Q9UMX1 BXGT021778 Suppressor of fused homolog 51684 reviewed
Q9Y4D7 BXGT022275 Plexin-D1 23129 reviewed
P43146 BXGT022852 Netrin receptor DCC 1630 reviewed
P35240 BXGT022927 Merlin 4771 reviewed
O14793 BXGT023280 Growth/differentiation factor 8 2660 reviewed Signaling
Q13635 BXGT024910 Protein patched homolog 1 5727 reviewed
P35250 BXGT025854 Replication factor C subunit 2 5982 reviewed Enzyme
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease