adisease

Showing entry for Adult Ependymoma

General Disease Information
BXGD Id	BXGD006605
Disease Name	Adult Ependymoma
Disease CUI Id	C0278874
MeSH Codes	C04
Disease Class Name	Neoplasms
Semantic Type	Neoplastic Process
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O00329	BXGT003909	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	5293	reviewed	Kinase
O14745	BXGT004090	Na(+)/H(+) exchange regulatory cofactor NHE-RF1	9368	reviewed
O75874	BXGT005157	Isocitrate dehydrogenase [NADP] cytoplasmic	3417	reviewed
P00533	BXGT005575	Epidermal growth factor receptor	1956	reviewed	Kinase
P00747	BXGT005639	Plasminogen	5340	reviewed	Enzyme
P02766	BXGT005953	Transthyretin	7276	reviewed	Transporter
P04271	BXGT006177	Protein S100-B	6285	reviewed	Calcium-binding protein
P04637	BXGT006243	Cellular tumor antigen p53	7157	reviewed	Transcription factor
P05231	BXGT006345	Interleukin-6	3569	reviewed
P06703	BXGT006477	Protein S100-A6	6277	reviewed	Calcium-binding protein
P08183	BXGT006741	ATP-dependent translocase ABCB1	5243	reviewed	Transporter
P08473	BXGT006773	Neprilysin	4311	reviewed	Enzyme
P08581	BXGT006794	Hepatocyte growth factor receptor	4233	reviewed	Kinase
P09619	BXGT006911	Platelet-derived growth factor receptor beta	5159	reviewed	Kinase
P10145	BXGT007542	Interleukin-8	3576	reviewed	Signaling
P10721	BXGT007605	Mast/stem cell growth factor receptor Kit	3815	reviewed	Kinase
P11137	BXGT007656	Microtubule-associated protein 2	4133	reviewed
P11362	BXGT007693	Fibroblast growth factor receptor 1	2260	reviewed	Kinase
P12314	BXGT007798	High affinity immunoglobulin gamma Fc receptor I	2209	reviewed	Cell adhesion
P14416	BXGT008011	D(2) dopamine receptor	1813	reviewed	G-protein coupled receptor
P14550	BXGT008019	Aldo-keto reductase family 1 member A1	10327	reviewed	Enzyme
P15153	BXGT008090	Ras-related C3 botulinum toxin substrate 2	5880	reviewed	Enzyme modulator
P15692	BXGT008147	Vascular endothelial growth factor A	7422	reviewed	Signaling
P15941	BXGT008176	Mucin-1	4582	reviewed
P16070	BXGT008186	CD44 antigen	960	reviewed
P16234	BXGT008209	Platelet-derived growth factor receptor alpha	5156	reviewed	Kinase
P16455	BXGT008229	Methylated-DNA--protein-cysteine methyltransferase	4255	reviewed
P21728	BXGT008686	D(1A) dopamine receptor	1812	reviewed	G-protein coupled receptor
P22607	BXGT008784	Fibroblast growth factor receptor 3	2261	reviewed	Kinase
P23297	BXGT008848	Protein S100-A1	6271	reviewed	Calcium-binding protein
P23921	BXGT008927	Ribonucleoside-diphosphate reductase large subunit	6240	reviewed	Enzyme
P24385	BXGT008965	G1/S-specific cyclin-D1	595	reviewed	Enzyme modulator
P26447	BXGT009114	Protein S100-A4	6275	reviewed	Calcium-binding protein
P27797	BXGT009206	Calreticulin	811	reviewed	Calcium-binding protein
P28222	BXGT009238	5-hydroxytryptamine receptor 1B	3351	reviewed	G-protein coupled receptor
P29034	BXGT009309	Protein S100-A2	6273	reviewed	Calcium-binding protein
P29323	BXGT009334	Ephrin type-B receptor 2	2048	reviewed	Kinase
P30988	BXGT009491	Calcitonin receptor	799	reviewed	G-protein coupled receptor
P32004	BXGT009594	Neural cell adhesion molecule L1	3897	reviewed
P35968	BXGT009887	Vascular endothelial growth factor receptor 2	3791	reviewed	Kinase
P36222	BXGT009914	Chitinase-3-like protein 1	1116	reviewed
P37840	BXGT010015	Alpha-synuclein	6622	reviewed	Transporter
P40763	BXGT010202	Signal transducer and activator of transcription 3	6774	reviewed	Nucleic acid binding
P42336	BXGT010302	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	5290	reviewed	Kinase
P42338	BXGT010303	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	5291	reviewed	Kinase
P46100	BXGT010508	Transcriptional regulator ATRX	546	reviewed
P46531	BXGT010526	Neurogenic locus notch homolog protein 1	4851	reviewed
P46937	BXGT010554	Transcriptional coactivator YAP1	10413	reviewed	Enzyme modulator
P48029	BXGT010606	Sodium- and chloride-dependent creatine transporter 1	6535	reviewed	Transporter
P48736	BXGT010658	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	5294	reviewed	Kinase
P53355	BXGT010985	Death-associated protein kinase 1	1612	reviewed	Kinase
P57059	BXGT011210	Serine/threonine-protein kinase SIK1	150094	reviewed
P60484	BXGT011307	Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN	5728	reviewed	Enzyme
P78504	BXGT011844	Protein jagged-1	182	reviewed
Q00534	BXGT012533	Cyclin-dependent kinase 6	1021	reviewed	Kinase
Q00987	BXGT012559	E3 ubiquitin-protein ligase Mdm2	4193	reviewed	Nucleic acid binding
Q04206	BXGT012754	Transcription factor p65	5970	reviewed	Transcription factor
Q09428	BXGT013036	ATP-binding cassette sub-family C member 8	6833	reviewed	Transporter
Q13509	BXGT013366	Tubulin beta-3 chain	10381	reviewed	Cellular structure
Q13510	BXGT013367	Acid ceramidase	427	reviewed	Enzyme
Q13569	BXGT013378	G/T mismatch-specific thymine DNA glycosylase	6996	reviewed
Q13938	BXGT013405	Calcyphosin	828	reviewed
Q14790	BXGT013505	Caspase-8	841	reviewed	Enzyme
Q15465	BXGT013573	Sonic hedgehog protein	6469	reviewed
Q15910	BXGT013612	Histone-lysine N-methyltransferase EZH2	2146	reviewed	Epigenetic regulator
Q16637	BXGT013646	Survival motor neuron protein	6607	reviewed	Epigenetic regulator
Q6N021	BXGT016378	Methylcytosine dioxygenase TET2	54790	reviewed
Q6ZQY3	BXGT016636	Acidic amino acid decarboxylase GADL1	339896	reviewed
Q96A70	BXGT019615	Antizyme inhibitor 2	113451	reviewed	Enzyme
Q9NZQ7	BXGT021281	Programmed cell death 1 ligand 1	29126	reviewed	Receptor
Q9UI32	BXGT021711	Glutaminase liver isoform, mitochondrial	27165	reviewed	Enzyme
Q9Y219	BXGT022206	Protein jagged-2	3714	reviewed
P35240	BXGT022927	Merlin	4771	reviewed
P25054	BXGT022961	Adenomatous polyposis coli protein	324	reviewed
P09471	BXGT026153	Guanine nucleotide-binding protein G(o) subunit alpha	2775	reviewed	Enzyme modulator

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}