adisease

Showing entry for early pregnancy

General Disease Information
BXGD Id	BXGD010184
Disease Name	early pregnancy
Disease CUI Id	C0747845
MeSH Codes
Disease Class Name
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id
Disease Ontology Class Name
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
O00141	BXGT003882	Serine/threonine-protein kinase Sgk1	6446	reviewed	Kinase
O00182	BXGT003889	Galectin-9	3965	reviewed	Signaling
O00206	BXGT003894	Toll-like receptor 4	7099	reviewed
O00238	BXGT003900	Bone morphogenetic protein receptor type-1B	658	reviewed	Kinase
O00329	BXGT003909	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	5293	reviewed	Kinase
O00519	BXGT003934	Fatty-acid amide hydrolase 1	2166	reviewed
O15123	BXGT004130	Angiopoietin-2	285	reviewed	Signaling
O43157	BXGT004572	Plexin-B1	5364	reviewed
O43524	BXGT004599	Forkhead box protein O3	2309	reviewed
O43915	BXGT004636	Vascular endothelial growth factor D	2277	reviewed	Signaling
O75015	BXGT005095	Low affinity immunoglobulin gamma Fc region receptor III-B	2215	reviewed	Cell adhesion
O75460	BXGT005127	Serine/threonine-protein kinase/endoribonuclease IRE1	2081	reviewed	Kinase
O94813	BXGT005337	Slit homolog 2 protein	9353	reviewed
O94907	BXGT005340	Dickkopf-related protein 1	22943	reviewed
P00374	BXGT005520	Dihydrofolate reductase	1719	reviewed	Enzyme
P00480	BXGT005551	Ornithine carbamoyltransferase, mitochondrial	5009	reviewed
P00533	BXGT005575	Epidermal growth factor receptor	1956	reviewed	Kinase
P01137	BXGT005737	Transforming growth factor beta-1 proprotein	7040	reviewed	Signaling
P01189	BXGT005742	Pro-opiomelanocortin	5443	reviewed
P01215	BXGT005743	Glycoprotein hormones alpha chain	1081	reviewed
P01236	BXGT005744	Prolactin	5617	reviewed	Signaling
P01375	BXGT005753	Tumor necrosis factor	7124	reviewed	Signaling
P01579	BXGT005770	Interferon gamma	3458	reviewed
P01584	BXGT005772	Interleukin-1 beta	3553	reviewed
P02741	BXGT005936	C-reactive protein	1401	reviewed
P03372	BXGT006059	Estrogen receptor	2099	reviewed	Nuclear receptor
P04083	BXGT006147	Annexin A1	301	reviewed
P04278	BXGT006182	Sex hormone-binding globulin	6462	reviewed
P04637	BXGT006243	Cellular tumor antigen p53	7157	reviewed	Transcription factor
P04798	BXGT006265	Cytochrome P450 1A1	1543	reviewed	Enzyme
P05108	BXGT006317	Cholesterol side-chain cleavage enzyme, mitochondrial	1583	reviewed
P05109	BXGT006318	Protein S100-A8	6279	reviewed	Calcium-binding protein
P05121	BXGT006320	Plasminogen activator inhibitor 1	5054	reviewed	Enzyme modulator
P05231	BXGT006345	Interleukin-6	3569	reviewed
P06401	BXGT006436	Progesterone receptor	5241	reviewed	Nuclear receptor
P06702	BXGT006476	Protein S100-A9	6280	reviewed	Calcium-binding protein
P06850	BXGT006511	Corticoliberin	1392	reviewed	Signaling
P07202	BXGT006565	Thyroid peroxidase	7173	reviewed	Enzyme
P07996	BXGT006710	Thrombospondin-1	7057	reviewed
P08183	BXGT006741	ATP-dependent translocase ABCB1	5243	reviewed	Transporter
P08253	BXGT006757	72 kDa type IV collagenase	4313	reviewed	Enzyme
P08254	BXGT006758	Stromelysin-1	4314	reviewed	Enzyme
P08637	BXGT006802	Low affinity immunoglobulin gamma Fc region receptor III-A	2214	reviewed	Cell adhesion
P08758	BXGT006821	Annexin A5	308	reviewed
P09038	BXGT006851	Fibroblast growth factor 2	2247	reviewed	Signaling
P09237	BXGT006874	Matrilysin	4316	reviewed	Enzyme
P09238	BXGT006875	Stromelysin-2	4319	reviewed	Enzyme
P09466	BXGT006892	Glycodelin	5047	reviewed	Enzyme
P09488	BXGT006899	Glutathione S-transferase Mu 1	2944	reviewed
P09769	BXGT006917	Tyrosine-protein kinase Fgr	2268	reviewed	Kinase
P10415	BXGT007567	Apoptosis regulator Bcl-2	596	reviewed	Signaling
P10644	BXGT007597	cAMP-dependent protein kinase type I-alpha regulatory subunit	5573	reviewed
P10747	BXGT007609	T-cell-specific surface glycoprotein CD28	940	reviewed
P11166	BXGT007661	Solute carrier family 2, facilitated glucose transporter member 1	6513	reviewed	Transporter
P11362	BXGT007693	Fibroblast growth factor receptor 1	2260	reviewed	Kinase
P11473	BXGT007709	Vitamin D3 receptor	7421	reviewed	Nuclear receptor
P11511	BXGT007717	Aromatase	1588	reviewed	Enzyme
P11926	BXGT007760	Ornithine decarboxylase	4953	reviewed	Enzyme
P12643	BXGT007830	Bone morphogenetic protein 2	650	reviewed	Signaling
P13236	BXGT007891	C-C motif chemokine 4	6351	reviewed
P13500	BXGT007916	C-C motif chemokine 2	6347	reviewed	Signaling
P13501	BXGT007917	C-C motif chemokine 5	6352	reviewed	Signaling
P13861	BXGT007961	cAMP-dependent protein kinase type II-alpha regulatory subunit	5576	reviewed
P14060	BXGT007978	3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1	3283	reviewed	Enzyme
P14780	BXGT008053	Matrix metalloproteinase-9	4318	reviewed	Enzyme
P15090	BXGT008079	Fatty acid-binding protein, adipocyte	2167	reviewed
P15531	BXGT008136	Nucleoside diphosphate kinase A	4830	reviewed	Kinase
P15692	BXGT008147	Vascular endothelial growth factor A	7422	reviewed	Signaling
P17931	BXGT008356	Galectin-3	3958	reviewed	Signaling
P18440	BXGT008404	Arylamine N-acetyltransferase 1	9	reviewed	Enzyme
P19883	BXGT008528	Follistatin	10468	reviewed	Enzyme modulator
P20248	BXGT008554	Cyclin-A2	890	reviewed	Enzyme modulator
P21802	BXGT008691	Fibroblast growth factor receptor 2	2263	reviewed	Kinase
P22083	BXGT008727	Alpha-(1,3)-fucosyltransferase 4	2526	reviewed	Enzyme
P22736	BXGT008800	Nuclear receptor subfamily 4 group A member 1	3164	reviewed	Nuclear receptor
P23560	BXGT008883	Brain-derived neurotrophic factor	627	reviewed	Signaling
P25440	BXGT009044	Bromodomain-containing protein 2	6046	reviewed	Epigenetic regulator
P27797	BXGT009206	Calreticulin	811	reviewed	Calcium-binding protein
P28845	BXGT009297	Corticosteroid 11-beta-dehydrogenase isozyme 1	3290	reviewed
P29474	BXGT009352	Nitric oxide synthase, endothelial	4846	reviewed
P30556	BXGT009441	Type-1 angiotensin II receptor	185	reviewed	G-protein coupled receptor
P30711	BXGT009460	Glutathione S-transferase theta-1	2952	reviewed
P32119	BXGT009600	Peroxiredoxin-2	7001	reviewed	Enzyme
P33681	BXGT009739	T-lymphocyte activation antigen CD80	941	reviewed
P35222	BXGT009799	Catenin beta-1	1499	reviewed
P35354	BXGT009816	Prostaglandin G/H synthase 2	5743	reviewed	Enzyme
P35869	BXGT009877	Aryl hydrocarbon receptor	196	reviewed	Transcription factor
P35968	BXGT009887	Vascular endothelial growth factor receptor 2	3791	reviewed	Kinase
P36894	BXGT009939	Bone morphogenetic protein receptor type-1A	657	reviewed	Kinase
P37231	BXGT009972	Peroxisome proliferator-activated receptor gamma	5468	reviewed	Nuclear receptor
P38484	BXGT010042	Interferon gamma receptor 2	3460	reviewed	Receptor
P41182	BXGT010231	B-cell lymphoma 6 protein	604	reviewed
P42336	BXGT010302	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	5290	reviewed	Kinase
P42338	BXGT010303	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	5291	reviewed	Kinase
P42898	BXGT010344	Methylenetetrahydrofolate reductase	4524	reviewed
P43490	BXGT010395	Nicotinamide phosphoribosyltransferase	10135	reviewed	Signaling
P45452	BXGT010462	Collagenase 3	4322	reviewed	Enzyme
P48061	BXGT010616	Stromal cell-derived factor 1	6387	reviewed
P48736	BXGT010658	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	5294	reviewed	Kinase
P48775	BXGT010662	Tryptophan 2,3-dioxygenase	6999	reviewed	Enzyme
P49763	BXGT010737	Placenta growth factor	5228	reviewed	Signaling
P49908	BXGT010760	Selenoprotein P	6414	reviewed	Extracellular structure
P51114	BXGT010832	Fragile X mental retardation syndrome-related protein 1	8087	reviewed	Nucleic acid binding
P51681	BXGT010878	C-C chemokine receptor type 5	1234	reviewed	G-protein coupled receptor
P51684	BXGT010880	C-C chemokine receptor type 6	1235	reviewed	G-protein coupled receptor
P55087	BXGT011105	Aquaporin-4	361	reviewed	Ion channel
P56937	BXGT011205	3-keto-steroid reductase	51478	reviewed
P60568	BXGT011315	Interleukin-2	3558	reviewed
P61073	BXGT011352	C-X-C chemokine receptor type 4	7852	reviewed	G-protein coupled receptor
P78556	BXGT011849	C-C motif chemokine 20	6364	reviewed	Signaling
P80365	BXGT011895	Corticosteroid 11-beta-dehydrogenase isozyme 2	3291	reviewed	Enzyme
Q00987	BXGT012559	E3 ubiquitin-protein ligase Mdm2	4193	reviewed	Nucleic acid binding
Q02790	BXGT012672	Peptidyl-prolyl cis-trans isomerase FKBP4	2288	reviewed	Enzyme
Q06830	BXGT012894	Peroxiredoxin-1	5052	reviewed	Enzyme
Q07869	BXGT012945	Peroxisome proliferator-activated receptor alpha	5465	reviewed	Nuclear receptor
Q13237	BXGT013331	cGMP-dependent protein kinase 2	5593	reviewed	Kinase
Q13418	BXGT013351	Integrin-linked protein kinase	3611	reviewed	Kinase
Q13873	BXGT013398	Bone morphogenetic protein receptor type-2	659	reviewed	Kinase
Q14126	BXGT013446	Desmoglein-2	1829	reviewed	Cell adhesion
Q14676	BXGT013497	Mediator of DNA damage checkpoint protein 1	9656	reviewed
Q15116	BXGT013539	Programmed cell death protein 1	5133	reviewed
Q15125	BXGT013543	3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	10682	reviewed	Enzyme
Q15303	BXGT013557	Receptor tyrosine-protein kinase erbB-4	2066	reviewed	Kinase
Q15389	BXGT013564	Angiopoietin-1	284	reviewed	Signaling
Q15596	BXGT013582	Nuclear receptor coactivator 2	10499	reviewed	Enzyme
Q15848	BXGT013609	Adiponectin	9370	reviewed
Q16620	BXGT013645	BDNF/NT-3 growth factors receptor	4915	reviewed	Kinase
Q16647	BXGT013648	Prostacyclin synthase	5740	reviewed
Q16665	BXGT013653	Hypoxia-inducible factor 1-alpha	3091	reviewed	Transcription factor
Q16695	BXGT013657	Histone H3.1t	8290	reviewed
Q16875	BXGT013686	6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3	5209	reviewed	Kinase
Q53EL6	BXGT015008	Programmed cell death protein 4	27250	reviewed	Nucleic acid binding
Q6UWP2	BXGT016567	Dehydrogenase/reductase SDR family member 11	79154	reviewed	Enzyme
Q6ZN17	BXGT016631	Protein lin-28 homolog B	389421	reviewed
Q86V24	BXGT017615	Adiponectin receptor protein 2	79602	reviewed	Receptor
Q8TDQ0	BXGT018810	Hepatitis A virus cellular receptor 2	84868	reviewed
Q8WZ42	BXGT019023	Titin	7273	reviewed	Kinase
Q92731	BXGT019366	Estrogen receptor beta	2100	reviewed	Nuclear receptor
Q92769	BXGT019370	Histone deacetylase 2	3066	reviewed	Epigenetic regulator
Q92905	BXGT019393	COP9 signalosome complex subunit 5	10987	reviewed	Enzyme
Q93009	BXGT019455	Ubiquitin carboxyl-terminal hydrolase 7	7874	reviewed	Enzyme
Q99707	BXGT019952	Methionine synthase	4548	reviewed
Q9BSQ5	BXGT020123	Cerebral cavernous malformations 2 protein	83605	reviewed
Q9BZS1	BXGT020203	Forkhead box protein P3	50943	reviewed
Q9C0B1	BXGT020209	Alpha-ketoglutarate-dependent dioxygenase FTO	79068	reviewed
Q9H3M7	BXGT020462	Thioredoxin-interacting protein	10628	reviewed
Q9NZQ7	BXGT021281	Programmed cell death 1 ligand 1	29126	reviewed	Receptor
Q9UBK8	BXGT021655	Methionine synthase reductase	4552	reviewed
Q9UGL1	BXGT021685	Lysine-specific demethylase 5B	10765	reviewed	Epigenetic regulator
Q9UHV8	BXGT021706	Galactoside-binding soluble lectin 13	29124	reviewed	Signaling
Q9UKU7	BXGT021749	Isobutyryl-CoA dehydrogenase, mitochondrial	27034	reviewed	Enzyme
Q9UQF0	BXGT021812	Syncytin-1	30816	reviewed
Q9Y5P4	BXGT022298	Collagen type IV alpha-3-binding protein	10087	reviewed	Transporter
Q9Y6Y9	BXGT022346	Lymphocyte antigen 96	23643	reviewed	Receptor
P16284	BXGT022972	Platelet endothelial cell adhesion molecule	5175	reviewed	Cell adhesion
Q8TBZ3	BXGT023141	WD repeat-containing protein 20	91833	reviewed
Q13007	BXGT023883	Interleukin-24	11009	reviewed
P15260	BXGT023924	Interferon gamma receptor 1	3459	reviewed	Receptor
P29590	BXGT024350	Protein PML	5371	reviewed
Q96A54	BXGT024681	Adiponectin receptor protein 1	51094	reviewed	Receptor
P27918	BXGT025485	Properdin	5199	reviewed
Q969H8	BXGT025606	Myeloid-derived growth factor	56005	reviewed
P00403	BXGT026137	Cytochrome c oxidase subunit 2	4513	reviewed	Enzyme

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}