Showing entry for Acute Coronary Syndrome


　 　 　 　 　 　 　 　 　 　 　 　 　 　 　 　
General Disease Information
BXGD IdBXGD011504
Disease NameAcute Coronary Syndrome
Disease CUI IdC0948089
MeSH Codes C14  
Disease Class NameCardiovascular Diseases
Semantic TypeDisease or Syndrome
Human Phenotype Ontology Id   
Human Phenotype Ontology Term
Disease Ontology Id   
Disease Ontology Class Name
Disorder Network disorder-protein-compound-food associations
The  disease-related  target proteins
Proteins
Uniport Id BXGT Id Protein Name Gene Status Protein Class
Uniport Id BXGT Id Protein name Gene Status Protein class
O00206 BXGT003894 Toll-like receptor 4 7099 reviewed
O14672 BXGT004081 Disintegrin and metalloproteinase domain-containing protein 10 102 reviewed
O15123 BXGT004130 Angiopoietin-2 285 reviewed Signaling
O60427 BXGT004875 Acyl-CoA (8-3)-desaturase 3992 reviewed
O60494 BXGT004879 Cubilin 8029 reviewed
O60603 BXGT004887 Toll-like receptor 2 7097 reviewed
O60674 BXGT004892 Tyrosine-protein kinase JAK2 3717 reviewed Kinase
O75173 BXGT005105 A disintegrin and metalloproteinase with thrombospondin motifs 4 9507 reviewed Enzyme
O94907 BXGT005340 Dickkopf-related protein 1 22943 reviewed
O94925 BXGT005342 Glutaminase kidney isoform, mitochondrial 2744 reviewed Enzyme
O95298 BXGT005371 NADH dehydrogenase [ubiquinone] 1 subunit C2 4718 reviewed Enzyme
O95445 BXGT005381 Apolipoprotein M 55937 reviewed
O95864 BXGT005403 Acyl-CoA 6-desaturase 9415 reviewed
P00450 BXGT005544 Ceruloplasmin 1356 reviewed Enzyme
P00533 BXGT005575 Epidermal growth factor receptor 1956 reviewed Kinase
P00734 BXGT005630 Prothrombin 2147 reviewed Enzyme
P00742 BXGT005636 Coagulation factor X 2159 reviewed Enzyme
P00747 BXGT005639 Plasminogen 5340 reviewed Enzyme
P00748 BXGT005640 Coagulation factor XII 2161 reviewed Enzyme
P00750 BXGT005642 Tissue-type plasminogen activator 5327 reviewed Enzyme
P00797 BXGT005658 Renin 5972 reviewed Enzyme
P01008 BXGT005713 Antithrombin-III 462 reviewed Enzyme modulator
P01019 BXGT005717 Angiotensinogen 183 reviewed Enzyme modulator
P01034 BXGT005721 Cystatin-C 1471 reviewed
P01130 BXGT005735 Low-density lipoprotein receptor 3949 reviewed
P01137 BXGT005737 Transforming growth factor beta-1 proprotein 7040 reviewed Signaling
P01270 BXGT005746 Parathyroid hormone 5741 reviewed
P01375 BXGT005753 Tumor necrosis factor 7124 reviewed Signaling
P01583 BXGT005771 Interleukin-1 alpha 3552 reviewed
P01584 BXGT005772 Interleukin-1 beta 3553 reviewed
P01589 BXGT005773 Interleukin-2 receptor subunit alpha 3559 reviewed Receptor
P01889 BXGT005809 HLA class I histocompatibility antigen, B-7 alpha chain 3106 reviewed
P01911 BXGT005816 HLA class II histocompatibility antigen, DRB1-15 beta chain 3123 reviewed Immune response
P02144 BXGT005853 Myoglobin 4151 reviewed
P02647 BXGT005908 Apolipoprotein A-I 335 reviewed
P02649 BXGT005909 Apolipoprotein E 348 reviewed
P02656 BXGT005913 Apolipoprotein C-III 345 reviewed
P02675 BXGT005916 Fibrinogen beta chain 2244 reviewed Signaling
P02741 BXGT005936 C-reactive protein 1401 reviewed
P02743 BXGT005937 Serum amyloid P-component 325 reviewed
P02766 BXGT005953 Transthyretin 7276 reviewed Transporter
P02768 BXGT005955 Serum albumin 213 reviewed Transporter
P02775 BXGT005960 Platelet basic protein 5473 reviewed Signaling
P03956 BXGT006120 Interstitial collagenase 4312 reviewed Enzyme
P04054 BXGT006136 Phospholipase A2 5319 reviewed Enzyme
P04083 BXGT006147 Annexin A1 301 reviewed
P04150 BXGT006154 Glucocorticoid receptor 2908 reviewed Nuclear receptor
P04179 BXGT006163 Superoxide dismutase [Mn], mitochondrial 6648 reviewed Enzyme
P04180 BXGT006164 Phosphatidylcholine-sterol acyltransferase 3931 reviewed Enzyme
P04275 BXGT006180 von Willebrand factor 7450 reviewed Enzyme modulator
P04278 BXGT006182 Sex hormone-binding globulin 6462 reviewed
P04406 BXGT006207 Glyceraldehyde-3-phosphate dehydrogenase 2597 reviewed Enzyme
P04798 BXGT006265 Cytochrome P450 1A1 1543 reviewed Enzyme
P05091 BXGT006312 Aldehyde dehydrogenase, mitochondrial 217 reviewed Enzyme
P05106 BXGT006315 Integrin beta-3 3690 reviewed Receptor
P05109 BXGT006318 Protein S100-A8 6279 reviewed Calcium-binding protein
P05120 BXGT006319 Plasminogen activator inhibitor 2 5055 reviewed Enzyme modulator
P05121 BXGT006320 Plasminogen activator inhibitor 1 5054 reviewed Enzyme modulator
P05154 BXGT006327 Plasma serine protease inhibitor 5104 reviewed Enzyme modulator
P05164 BXGT006333 Myeloperoxidase 4353 reviewed Enzyme
P05231 BXGT006345 Interleukin-6 3569 reviewed
P05362 BXGT006350 Intercellular adhesion molecule 1 3383 reviewed
P05413 BXGT006355 Fatty acid-binding protein, heart 2170 reviewed
P06396 BXGT006435 Gelsolin 2934 reviewed Cellular structure
P06702 BXGT006476 Protein S100-A9 6280 reviewed Calcium-binding protein
P06732 BXGT006489 Creatine kinase M-type 1158 reviewed Kinase
P06733 BXGT006490 Alpha-enolase 2023 reviewed Enzyme
P06870 BXGT006518 Kallikrein-1 3816 reviewed Enzyme
P07195 BXGT006563 L-lactate dehydrogenase B chain 3945 reviewed Enzyme
P07203 BXGT006566 Glutathione peroxidase 1 2876 reviewed Enzyme
P07204 BXGT006567 Thrombomodulin 7056 reviewed
P07339 BXGT006604 Cathepsin D 1509 reviewed Enzyme
P07550 BXGT006636 Beta-2 adrenergic receptor 154 reviewed G-protein coupled receptor
P07858 BXGT006689 Cathepsin B 1508 reviewed Enzyme
P08183 BXGT006741 ATP-dependent translocase ABCB1 5243 reviewed Transporter
P08235 BXGT006751 Mineralocorticoid receptor 4306 reviewed Nuclear receptor
P08253 BXGT006757 72 kDa type IV collagenase 4313 reviewed Enzyme
P08254 BXGT006758 Stromelysin-1 4314 reviewed Enzyme
P08514 BXGT006781 Integrin alpha-IIb 3674 reviewed
P08588 BXGT006795 Beta-1 adrenergic receptor 153 reviewed G-protein coupled receptor
P08670 BXGT006810 Vimentin 7431 reviewed
P08684 BXGT006812 Cytochrome P450 3A4 1576 reviewed Enzyme
P08709 BXGT006818 Coagulation factor VII 2155 reviewed Enzyme
P08758 BXGT006821 Annexin A5 308 reviewed
P08865 BXGT006832 40S ribosomal protein SA 3921 reviewed Nucleic acid binding
P09211 BXGT006869 Glutathione S-transferase P 2950 reviewed
P09429 BXGT006889 High mobility group protein B1 3146 reviewed Nucleic acid binding
P09601 BXGT006909 Heme oxygenase 1 3162 reviewed
P09917 BXGT006941 Arachidonate 5-lipoxygenase 240 reviewed Enzyme
P10145 BXGT007542 Interleukin-8 3576 reviewed Signaling
P10415 BXGT007567 Apoptosis regulator Bcl-2 596 reviewed Signaling
P10635 BXGT007595 Cytochrome P450 2D6 1565 reviewed
P10646 BXGT007598 Tissue factor pathway inhibitor 7035 reviewed Enzyme modulator
P10747 BXGT007609 T-cell-specific surface glycoprotein CD28 940 reviewed
P10809 BXGT007617 60 kDa heat shock protein, mitochondrial 3329 reviewed
P10909 BXGT007630 Clusterin 1191 reviewed
P11142 BXGT007658 Heat shock cognate 71 kDa protein 3312 reviewed
P11226 BXGT007675 Mannose-binding protein C 4153 reviewed Receptor
P11597 BXGT007727 Cholesteryl ester transfer protein 1071 reviewed
P11712 BXGT007738 Cytochrome P450 2C9 1559 reviewed
P12277 BXGT007789 Creatine kinase B-type 1152 reviewed Kinase
P12821 BXGT007849 Angiotensin-converting enzyme 1636 reviewed Enzyme
P13500 BXGT007916 C-C motif chemokine 2 6347 reviewed Signaling
P13726 BXGT007950 Tissue factor 2152 reviewed Receptor
P13727 BXGT007951 Bone marrow proteoglycan 5553 reviewed Enzyme modulator
P14151 BXGT007990 L-selectin 6402 reviewed
P14174 BXGT007991 Macrophage migration inhibitory factor 4282 reviewed
P14210 BXGT007994 Hepatocyte growth factor 3082 reviewed Enzyme
P14550 BXGT008019 Aldo-keto reductase family 1 member A1 10327 reviewed Enzyme
P14555 BXGT008020 Phospholipase A2, membrane associated 5320 reviewed Enzyme
P14679 BXGT008039 Tyrosinase 7299 reviewed Enzyme
P14780 BXGT008053 Matrix metalloproteinase-9 4318 reviewed Enzyme
P14923 BXGT008069 Junction plakoglobin 3728 reviewed
P15090 BXGT008079 Fatty acid-binding protein, adipocyte 2167 reviewed
P15289 BXGT008102 Arylsulfatase A 410 reviewed Enzyme
P15692 BXGT008147 Vascular endothelial growth factor A 7422 reviewed Signaling
P16066 BXGT008185 Atrial natriuretic peptide receptor 1 4881 reviewed Kinase
P16109 BXGT008194 P-selectin 6403 reviewed
P16435 BXGT008226 NADPH--cytochrome P450 reductase 5447 reviewed
P16442 BXGT008227 Histo-blood group ABO system transferase 28 reviewed Enzyme
P16581 BXGT008245 E-selectin 6401 reviewed
P16662 BXGT008253 UDP-glucuronosyltransferase 2B7 7364 reviewed
P16671 BXGT008255 Platelet glycoprotein 4 948 reviewed Receptor
P16871 BXGT008269 Interleukin-7 receptor subunit alpha 3575 reviewed Receptor
P17342 BXGT008302 Atrial natriuretic peptide receptor 3 4883 reviewed
P17931 BXGT008356 Galectin-3 3958 reviewed Signaling
P17948 BXGT008358 Vascular endothelial growth factor receptor 1 2321 reviewed Kinase
P18089 BXGT008379 Alpha-2B adrenergic receptor 151 reviewed G-protein coupled receptor
P18146 BXGT008384 Early growth response protein 1 1958 reviewed Nucleic acid binding
P18206 BXGT008389 Vinculin 7414 reviewed
P18433 BXGT008403 Receptor-type tyrosine-protein phosphatase alpha 5786 reviewed Enzyme
P18505 BXGT008409 Gamma-aminobutyric acid receptor subunit beta-1 2560 reviewed Ion channel
P19320 BXGT008470 Vascular cell adhesion protein 1 7412 reviewed
P19429 BXGT008479 Troponin I, cardiac muscle 7137 reviewed Cellular structure
P19838 BXGT008526 Nuclear factor NF-kappa-B p105 subunit 4790 reviewed Transcription factor
P20292 BXGT008561 Arachidonate 5-lipoxygenase-activating protein 241 reviewed Enzyme
P20618 BXGT008589 Proteasome subunit beta type-1 5689 reviewed
P20813 BXGT008603 Cytochrome P450 2B6 1555 reviewed
P20815 BXGT008604 Cytochrome P450 3A5 1577 reviewed Enzyme
P21980 BXGT008715 Protein-glutamine gamma-glutamyltransferase 2 7052 reviewed Enzyme
P22891 BXGT008813 Vitamin K-dependent protein Z 8858 reviewed Enzyme
P22894 BXGT008815 Neutrophil collagenase 4317 reviewed Enzyme
P23219 BXGT008837 Prostaglandin G/H synthase 1 5742 reviewed Enzyme
P23560 BXGT008883 Brain-derived neurotrophic factor 627 reviewed Signaling
P24298 BXGT008960 Alanine aminotransferase 1 2875 reviewed Enzyme
P25021 BXGT009004 Histamine H2 receptor 3274 reviewed G-protein coupled receptor
P25116 BXGT009025 Proteinase-activated receptor 1 2149 reviewed G-protein coupled receptor
P25942 BXGT009079 Tumor necrosis factor receptor superfamily member 5 958 reviewed
P27169 BXGT009161 Serum paraoxonase/arylesterase 1 5444 reviewed
P27352 BXGT009174 Cobalamin binding intrinsic factor 2694 reviewed
P27487 BXGT009187 Dipeptidyl peptidase 4 1803 reviewed Enzyme
P27708 BXGT009202 CAD protein 790 reviewed Enzyme
P29466 BXGT009349 Caspase-1 834 reviewed Enzyme
P29474 BXGT009352 Nitric oxide synthase, endothelial 4846 reviewed
P29965 BXGT009388 CD40 ligand 959 reviewed Signaling
P30101 BXGT009402 Protein disulfide-isomerase A3 2923 reviewed
P30556 BXGT009441 Type-1 angiotensin II receptor 185 reviewed G-protein coupled receptor
P30626 BXGT009450 Sorcin 6717 reviewed
P31749 BXGT009574 RAC-alpha serine/threonine-protein kinase 207 reviewed Kinase
P33261 BXGT009707 Cytochrome P450 2C19 1557 reviewed
P33681 BXGT009739 T-lymphocyte activation antigen CD80 941 reviewed
P34913 BXGT009770 Bifunctional epoxide hydrolase 2 2053 reviewed Enzyme
P34932 BXGT009772 Heat shock 70 kDa protein 4 3308 reviewed
P35354 BXGT009816 Prostaglandin G/H synthase 2 5743 reviewed Enzyme
P35557 BXGT009846 Glucokinase 2645 reviewed Kinase
P35613 BXGT009856 Basigin 682 reviewed
P35968 BXGT009887 Vascular endothelial growth factor receptor 2 3791 reviewed Kinase
P36955 BXGT009946 Pigment epithelium-derived factor 5176 reviewed Enzyme modulator
P37231 BXGT009972 Peroxisome proliferator-activated receptor gamma 5468 reviewed Nuclear receptor
P38398 BXGT010037 Breast cancer type 1 susceptibility protein 672 reviewed Enzyme
P40763 BXGT010202 Signal transducer and activator of transcription 3 6774 reviewed Nucleic acid binding
P40933 BXGT010209 Interleukin-15 3600 reviewed
P42898 BXGT010344 Methylenetetrahydrofolate reductase 4524 reviewed
P43116 BXGT010357 Prostaglandin E2 receptor EP2 subtype 5732 reviewed G-protein coupled receptor
P43220 BXGT010367 Glucagon-like peptide 1 receptor 2740 reviewed G-protein coupled receptor
P43489 BXGT010394 Tumor necrosis factor receptor superfamily member 4 7293 reviewed
P45379 BXGT010459 Troponin T, cardiac muscle 7139 reviewed Cellular structure
P45983 BXGT010494 Mitogen-activated protein kinase 8 5599 reviewed Kinase
P47712 BXGT010577 Cytosolic phospholipase A2 5321 reviewed Enzyme
P47900 BXGT010595 P2Y purinoceptor 1 5028 reviewed G-protein coupled receptor
P48023 BXGT010604 Tumor necrosis factor ligand superfamily member 6 356 reviewed Signaling
P48061 BXGT010616 Stromal cell-derived factor 1 6387 reviewed
P49327 BXGT010694 Fatty acid synthase 2194 reviewed Enzyme
P49585 BXGT010712 Choline-phosphate cytidylyltransferase A 5130 reviewed
P49789 BXGT010742 Bis(5'-adenosyl)-triphosphatase 2272 reviewed
P51681 BXGT010878 C-C chemokine receptor type 5 1234 reviewed G-protein coupled receptor
P51692 BXGT010885 Signal transducer and activator of transcription 5B 6777 reviewed Nucleic acid binding
P55040 BXGT011099 GTP-binding protein GEM 2669 reviewed
P60568 BXGT011315 Interleukin-2 3558 reviewed
P61769 BXGT011383 Beta-2-microglobulin 567 reviewed Immune response
P63261 BXGT011512 Actin, cytoplasmic 2 71 reviewed Cellular structure
P67936 BXGT011570 Tropomyosin alpha-4 chain 7171 reviewed Cellular structure
P78380 BXGT011841 Oxidized low-density lipoprotein receptor 1 4973 reviewed
P80188 BXGT011882 Neutrophil gelatinase-associated lipocalin 3934 reviewed Enzyme
P80511 BXGT011914 Protein S100-A12 6283 reviewed Calcium-binding protein
P81172 BXGT011935 Hepcidin 57817 reviewed
P98164 BXGT012230 Low-density lipoprotein receptor-related protein 2 4036 reviewed
Q07011 BXGT012912 Tumor necrosis factor receptor superfamily member 9 3604 reviewed
Q07869 BXGT012945 Peroxisome proliferator-activated receptor alpha 5465 reviewed Nuclear receptor
Q07954 BXGT012950 Prolow-density lipoprotein receptor-related protein 1 4035 reviewed
Q09428 BXGT013036 ATP-binding cassette sub-family C member 8 6833 reviewed Transporter
Q12772 BXGT013262 Sterol regulatory element-binding protein 2 6721 reviewed
Q13093 BXGT013310 Platelet-activating factor acetylhydrolase 7941 reviewed Enzyme
Q13219 BXGT013327 Pappalysin-1 5069 reviewed
Q13315 BXGT013339 Serine-protein kinase ATM 472 reviewed Kinase
Q13427 BXGT013354 Peptidyl-prolyl cis-trans isomerase G 9360 reviewed
Q14116 BXGT013442 Interleukin-18 3606 reviewed
Q14393 BXGT013466 Growth arrest-specific protein 6 2621 reviewed Extracellular structure
Q15848 BXGT013609 Adiponectin 9370 reviewed
Q16539 BXGT013634 Mitogen-activated protein kinase 14 1432 reviewed Kinase
Q86X55 BXGT017627 Histone-arginine methyltransferase CARM1 10498 reviewed Epigenetic regulator
Q8NBP7 BXGT018541 Proprotein convertase subtilisin/kexin type 9 255738 reviewed Enzyme
Q8NCC3 BXGT018546 Group XV phospholipase A2 23659 reviewed Enzyme
Q8TDS5 BXGT018813 Oxoeicosanoid receptor 1 165140 reviewed G-protein coupled receptor
Q8TDV0 BXGT018815 Probable G-protein coupled receptor 151 134391 reviewed G-protein coupled receptor
Q96AZ6 BXGT019621 Interferon-stimulated gene 20 kDa protein 3669 reviewed
Q96D42 BXGT019636 Hepatitis A virus cellular receptor 1 26762 reviewed
Q96EB6 BXGT019646 NAD-dependent protein deacetylase sirtuin-1 23411 reviewed Epigenetic regulator
Q96IY4 BXGT019678 Carboxypeptidase B2 1361 reviewed Enzyme
Q96J66 BXGT019680 ATP-binding cassette sub-family C member 11 85320 reviewed Transporter
Q96P20 BXGT019704 NACHT, LRR and PYD domains-containing protein 3 114548 reviewed
Q9BQB6 BXGT020108 Vitamin K epoxide reductase complex subunit 1 79001 reviewed Enzyme
Q9BQE3 BXGT020109 Tubulin alpha-1C chain 84790 reviewed Cellular structure
Q9BR01 BXGT020115 Sulfotransferase 4A1 25830 reviewed
Q9BYF1 BXGT020186 Angiotensin-converting enzyme 2 59272 reviewed Enzyme
Q9BZS1 BXGT020203 Forkhead box protein P3 50943 reviewed
Q9C0B1 BXGT020209 Alpha-ketoglutarate-dependent dioxygenase FTO 79068 reviewed
Q9H244 BXGT020448 P2Y purinoceptor 12 64805 reviewed G-protein coupled receptor
Q9H4B7 BXGT020475 Tubulin beta-1 chain 81027 reviewed Cellular structure
Q9H9B1 BXGT020501 Histone-lysine N-methyltransferase EHMT1 79813 reviewed Epigenetic regulator
Q9HCN6 BXGT020535 Platelet glycoprotein VI 51206 reviewed Receptor
Q9NP58 BXGT021143 ATP-binding cassette sub-family B member 6, mitochondrial 10058 reviewed Transporter
Q9NR19 BXGT021175 Acetyl-coenzyme A synthetase, cytoplasmic 55902 reviewed Enzyme
Q9UKV0 BXGT021750 Histone deacetylase 9 9734 reviewed Epigenetic regulator
Q9ULC5 BXGT021758 Long-chain-fatty-acid--CoA ligase 5 51703 reviewed Enzyme
Q9ULV1 BXGT021764 Frizzled-4 8322 reviewed G-protein coupled receptor
Q9UM07 BXGT021771 Protein-arginine deiminase type-4 23569 reviewed
Q9Y251 BXGT022215 Heparanase 10855 reviewed Enzyme
Q9Y2R2 BXGT022243 Tyrosine-protein phosphatase non-receptor type 22 26191 reviewed
Q9Y572 BXGT022289 Receptor-interacting serine/threonine-protein kinase 3 11035 reviewed Kinase
Q9Y5X9 BXGT022307 Endothelial lipase 9388 reviewed Enzyme
P04439 BXGT022649 HLA class I histocompatibility antigen, A-3 alpha chain 3105 reviewed
Q9NXB9 BXGT022660 Elongation of very long chain fatty acids protein 2 54898 reviewed Enzyme
P24462 BXGT022674 Cytochrome P450 3A7 1551 reviewed
P16284 BXGT022972 Platelet endothelial cell adhesion molecule 5175 reviewed Cell adhesion
Q16552 BXGT023419 Interleukin-17A 3605 reviewed
P00395 BXGT023596 Cytochrome c oxidase subunit 1 4512 reviewed Enzyme
Q12888 BXGT024878 TP53-binding protein 1 7158 reviewed Epigenetic regulator
Q969H8 BXGT025606 Myeloid-derived growth factor 56005 reviewed
Q9UKU9 BXGT025985 Angiopoietin-related protein 2 23452 reviewed Signaling
P00403 BXGT026137 Cytochrome c oxidase subunit 2 4513 reviewed Enzyme
Q08477 BXGT026164 Docosahexaenoic acid omega-hydroxylase CYP4F3 4051 reviewed Enzyme
The  disease-related  compounds
Compounds
BXGC Id Compound Name Structure Molecular Weight Number of targets?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease
The  disease-related  foods
Foods
BXGF Id Food Name Scientific Name Food Group Number of compounds in food?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease