adisease

Showing entry for Brooke-Spiegler syndrome

General Disease Information
BXGD Id	BXGD015756
Disease Name	Brooke-Spiegler syndrome
Disease CUI Id	C1857941
MeSH Codes	C16 C04 C17
Disease Class Name	Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Neoplasms; Skin and Connective Tissue Diseases
Semantic Type	Disease or Syndrome
Human Phenotype Ontology Id
Human Phenotype Ontology Term
Disease Ontology Id	DOID:630
Disease Ontology Class Name	genetic disease
Disorder Network	disorder-protein-compound-food associations

The disease-related target proteins

Proteins

Uniport Id	BXGT Id	Protein Name	Gene	Status	Protein Class
Uniport Id	BXGT Id	Protein name	Gene	Status	Protein class
P01024	BXGT005719	Complement C3	718	reviewed	Enzyme modulator
P01133	BXGT005736	Pro-epidermal growth factor	1950	reviewed
P01275	BXGT005747	Glucagon	2641	reviewed
P01584	BXGT005772	Interleukin-1 beta	3553	reviewed
P04275	BXGT006180	von Willebrand factor	7450	reviewed	Enzyme modulator
P04637	BXGT006243	Cellular tumor antigen p53	7157	reviewed	Transcription factor
P07359	BXGT006612	Platelet glycoprotein Ib alpha chain	2811	reviewed	Receptor
P10415	BXGT007567	Apoptosis regulator Bcl-2	596	reviewed	Signaling
P11926	BXGT007760	Ornithine decarboxylase	4953	reviewed	Enzyme
P13224	BXGT007890	Platelet glycoprotein Ib beta chain	2812	reviewed
P21802	BXGT008691	Fibroblast growth factor receptor 2	2263	reviewed	Kinase
P21817	BXGT008693	Ryanodine receptor 1	6261	reviewed	Ion channel
P27487	BXGT009187	Dipeptidyl peptidase 4	1803	reviewed	Enzyme
P28482	BXGT009263	Mitogen-activated protein kinase 1	5594	reviewed	Kinase
P29466	BXGT009349	Caspase-1	834	reviewed	Enzyme
P39019	BXGT010082	40S ribosomal protein S19	6223	reviewed	Nucleic acid binding
P43220	BXGT010367	Glucagon-like peptide 1 receptor	2740	reviewed	G-protein coupled receptor
P46059	BXGT010500	Solute carrier family 15 member 1	6564	reviewed	Transporter
P46108	BXGT010509	Adapter molecule crk	1398	reviewed
P50613	BXGT010815	Cyclin-dependent kinase 7	1022	reviewed	Kinase
Q13155	BXGT013320	Aminoacyl tRNA synthase complex-interacting multifunctional protein 2	7965	reviewed
Q15848	BXGT013609	Adiponectin	9370	reviewed
Q16539	BXGT013634	Mitogen-activated protein kinase 14	1432	reviewed	Kinase
Q96P20	BXGT019704	NACHT, LRR and PYD domains-containing protein 3	114548	reviewed
Q9H9B1	BXGT020501	Histone-lysine N-methyltransferase EHMT1	79813	reviewed	Epigenetic regulator
Q9HC29	BXGT020526	Nucleotide-binding oligomerization domain-containing protein 2	64127	reviewed	Enzyme

The disease-related compounds

Compounds

BXGC Id	Compound Name	Structure	Molecular Weight	Number of targets^{?Number of times compound connecting the disease , higher numbers indicate the compound is more associated with the disease}

The disease-related foods

Foods

BXGF Id	Food Name	Scientific Name	Food Group	Number of compounds in food^{?Number of compounds in food that connecting disease, higher numbers indicate the more compounds in food are more associated with the dusease}